Archives
RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.
22 Sep, 2021 | 10:03h | UTCEffect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)
Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond.
22 Sep, 2021 | 09:57h | UTC
Cluster RCT: Procalcitonin point-of-care testing may reduce antibiotic prescription for patients with suspected lower respiratory tract infection in primary care.
22 Sep, 2021 | 10:01h | UTC
Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.
22 Sep, 2021 | 10:02h | UTC
[Press release – not published yet] Pfizer announces COVID-19 vaccine in children 5 to 11 years produced strong neutralizing antibody responses.
21 Sep, 2021 | 09:57h | UTCCommentaries:
Pfizer says COVID-19 vaccine safe, effective in younger children – CIDRAP
Commentaries on Twitter
I'm so glad to see that Pfizer has data to submit for their vaccine for 5-11 year olds. But any strong assertions about safety, such as for low incidence side-effects like myocarditis, cannot made from a trial of ~1500 children.
— Eric Topol (@EricTopol) September 20, 2021
(thread – click for more)
BREAKING NEWS: Pfizer releases results of 5-11 year old trial for its vaccine. 2-dose 10 microgram regimen (Pfizer uses 30 mcg for 12 and up) administered 21 days apart (sigh, we now know we need longer duration between doses for better effectiveness)https://t.co/43MHnlZgqg
— Monica Gandhi MD, MPH (@MonicaGandhi9) September 20, 2021
(thread – click for more)
https://twitter.com/hildabast/status/1439976038964940803
Guidelines Summary: Management of Indwelling Pleural Catheters.
22 Sep, 2021 | 10:00h | UTC
Residual excessive daytime sleepiness in patients treated for obstructive sleep apnea: guidance for assessment, diagnosis, and management.
22 Sep, 2021 | 09:56h | UTC
The Evolution of Hemodynamic Monitoring and Support.
22 Sep, 2021 | 09:58h | UTCHemodynamic Monitoring and Support – Critical Care Medicine
Commentary on Twitter
Evolution of hemodynamic monitoring for #CriticalCare#TBT for #SCCM50Years #SCCMSoMe from @jlvincen @BerndSaugel in @CritCareMedhttps://t.co/T4lr1ltGoW pic.twitter.com/mOQ2LhdXLx
— Lauren R. Sorce, PhD, RN, CPNP-AC/PC, FAAN, FCCM (@SCCMPresident) July 22, 2021
M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the standard of care for hospitalized patients with COVID-19 who do not have an indication for therapeutic anticoagulation, irrespective of disease severity.
21 Sep, 2021 | 09:54h | UTC
Commentary on Twitter (thread – click for more)
Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with #COVID-19: A systematic review and meta-analysis of randomized controlled trials https://t.co/Gkdfp9vn75 @ESC_Journals @escardio @ESCardioNews #COVID19
— Luis Ortega Paz (@Ortega_Paz) September 15, 2021
Uncoupling vaccination from politics: a call to action.
21 Sep, 2021 | 09:56h | UTCUncoupling vaccination from politics: a call to action – The Lancet
COVID will likely shift from pandemic to endemic — but what does that mean?
21 Sep, 2021 | 09:49h | UTCCOVID will likely shift from pandemic to endemic — but what does that mean? – The Conversation
An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy.
21 Sep, 2021 | 09:51h | UTC
Case series: Assessment of silicone particle migration among women undergoing removal or revision of silicone breast implants in the Netherlands.
21 Sep, 2021 | 08:59h | UTCInvited commentary: Silicone Breast Implants and Disease—Many Questions Unanswered
Commentary on Twitter
In this case series including women w noncohesive or cohesive silicone gel breast implants, silicone leakage occurred in 98.8% of women, indicating silicone gel bleed, and in 86.6% of women, migration of silicone particles outside the capsule was detected. https://t.co/tyCpLw565Z
— JAMA Network Open (@JAMANetworkOpen) September 20, 2021
Effectiveness and Ethics of Incentives for Research Participation: 2 Randomized Clinical Trials.
21 Sep, 2021 | 08:57h | UTCEffectiveness and Ethics of Incentives for Research Participation: 2 Randomized Clinical Trials – JAMA Internal Medicine (free for a limited period)
Editorial: Evidence for the Ethics of Incentivizing Clinical Trial Enrollment? – JAMA Internal Medicine
Commentary on Twitter
In this study, financial incentives increased trial enrollment in one of two trials, and did not produce undue or unjust inducement or other unintended consequences in either trial https://t.co/SaCk1XinuO
— JAMA Internal Medicine (@JAMAInternalMed) September 20, 2021
AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.
21 Sep, 2021 | 09:03h | UTCNews release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons
Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons
Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline
Six rules that will define our second pandemic winter
21 Sep, 2021 | 09:47h | UTCSix Rules That Will Define Our Second Pandemic Winter – The Atlantic
KDIGO 2021 clinical practice guideline for the management of glomerular diseases.
21 Sep, 2021 | 09:05h | UTCExecutive summary: KDIGO 2021 Guideline for the Management of Glomerular Diseases – Kidney Disease: Improving Global Outcomes
RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.
21 Sep, 2021 | 09:01h | UTCEffect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)
Commentaries:
Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian
Commentary on Twitter
An Australian randomized clinical trial found that ‘pre-emptive’ therapy during infancy reduced #autism diagnostic behaviors and improved language ability across early childhood https://t.co/Sybbu4hRWL
— JAMA Pediatrics (@JAMAPediatrics) September 20, 2021
Editorial: Authorship and Publication Matters: Credit and Credibility.
21 Sep, 2021 | 08:54h | UTCAuthorship and Publication Matters: Credit and Credibility – Anesthesiology
Related: When is ‘self-plagiarism’ OK? New guidelines offer researchers rules for recycling text – Science
Commentary on Twitter
Anesthesiology editors focus on authorship and publication matters in a recent editorial examining journal policies on appropriate recognition for authors and collaborators. https://t.co/2NCpTEkpQW#PeerReviewWeek21 pic.twitter.com/lYtXtZD0l9
— Anesthesiology (@_Anesthesiology) September 20, 2021
Systematic review: Interventions to Reduce Hospital Length of Stay in High-risk Populations.
21 Sep, 2021 | 08:58h | UTC
Review: Transfusion-related acute lung injury in the perioperative patient.
21 Sep, 2021 | 08:56h | UTCTransfusion-related Acute Lung Injury in the Perioperative Patient – Anesthesiology
Podcast: Advance Your Care Planning.
21 Sep, 2021 | 08:51h | UTC#295 Advance Your Care Planning with Dr. Rebecca Sudore – The Curbsiders
5000 alcohol-related cancer deaths could be prevented every year by doubling alcohol taxes in the European Region, says WHO/Europe.
21 Sep, 2021 | 08:52h | UTCRelated:
Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization
The Lancet taskforce on NCDs and economics
To improve global health, tax the things that are killing us – Financial Times
Reducing cardiovascular disease burden through targeted dietary policies
Fiscal policies for the prevention of diseases
CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.
19 Sep, 2021 | 23:48h | UTCCommentaries:
CDC: Moderna COVID vaccine most protective against hospital cases – CIDRAP
CDC data: Moderna vaccine has edge in preventing COVID-19 hospitalizations – UPI
Commentary on Twitter
Turns out all vaccines are not equal! https://t.co/yP6eC6o78i via @CDCgov Among adults without immunocompromising conditions, vaccine effectiveness against COVID-19 hospitalization (Mar 11–Aug 15, 21) was ⬆️for @moderna_tx (93%) than @pfizer (88%) and @JNJNews vaccine (71%).
— Carlos del Rio (@CarlosdelRio7) September 17, 2021
Does everybody need a booster shot? – “Why some people might need Covid-19 booster shots — and some might not”.
19 Sep, 2021 | 23:43h | UTCDoes everybody need a booster shot? – Vox