Archives
Statins linked to reduced risk of death from COVID-19 in major population study – “Randomized studies will be needed to ascertain whether there is a causal relationship, note the researchers”.
15 Oct, 2021 | 02:47h | UTCNews release: Statins linked to reduced risk of death from COVID-19 in major population study – Karolinska Institutet
Original study: HMG-CoA reductase inhibitors and COVID-19 mortality in Stockholm, Sweden: A registry-based cohort study – PLOS Medicine
Commentaries:
Expert reaction to study looking at statins and risk of death from COVID-19 – Science Media Centre
People taking statins less likely to die from Covid, study suggests – The Guardian
Perspective | Trying to Block SARS-CoV-2 Transmission With Intranasal Vaccines.
15 Oct, 2021 | 02:44h | UTCTrying to Block SARS-CoV-2 Transmission With Intranasal Vaccines – JAMA
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
15 Oct, 2021 | 02:41h | UTCCovid-19 treatments and vaccines must be evaluated in pregnancy – The BMJ
Related:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
Inconsistent messaging from authorities, driven by lack of trial data, has increased covid-19 vaccine hesitancy among pregnant women@DrAllyah and colleagues argue that pregnant women should be included in drug and vaccine development from the outsethttps://t.co/P3v1ouk8tQ
— The BMJ (@bmj_latest) October 14, 2021
FDA panel green-lights Moderna COVID boosters for risk groups.
15 Oct, 2021 | 02:43h | UTCFDA panel green-lights Moderna COVID boosters for risk groups – CIDRAP
FDA issues food industry guidance for reduction of sodium in processed and packaged foods.
15 Oct, 2021 | 02:29h | UTCGuidance for Industry: Voluntary Sodium Reduction Goals – U.S. Food & Drug Administration
Commentaries:
FDA Issues New Guidance on Sodium Targets for Food Industry – TCTMD
Reducing Sodium Intake in the US: Healthier Lives, Healthier Future – JAMA
FDA Reduces Recommended Salt Levels in Americans’ Food – HealthDay
FDA guidance to food industry aims to reduce sodium consumption – American Heart Association
New FDA guidance aims to drastically cut salt in food supply – NBC News
Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.
15 Oct, 2021 | 02:38h | UTCRelated:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter (thread – click for more)
First dataset I have seen for vaccine efficacy in pregnant persons during #Delta era. Impressive aOR for both severe illness (0.11) and infection positivity in general (0.31)! #GetVaccinatedNow 🤰🏻💉 https://t.co/VhBHyeOWjz
— Lauren Hassen, MD MPH (@ljhassen) October 14, 2021
Systematic Review: “Formula milk trials have a high risk of bias, almost always report favorable conclusions, lack transparency, and selectively report findings”.
15 Oct, 2021 | 02:25h | UTCNews release: Formula milk trials are not reliable, warn researchers – Imperial College London
Original study: Conduct and reporting of formula milk trials: systematic review – The BMJ
WHO Report: Tuberculosis deaths rise for the first time in more than a decade due to the COVID-19 pandemic.
15 Oct, 2021 | 02:30h | UTCReport: Global tuberculosis report 2021
Commentary: Tuberculosis deaths rise for 1st time in years, due to COVID – Associated Press
Commentary on Twitter (thread – click for more)
🆕 WHO's Global TB Report reveals deaths from #tuberculosis rise for the first time in more than a decade due to the #COVID19 pandemic.
1.5 million people died in 2020 & the number will continue to rise unless urgent action is taken 👉https://t.co/RFmWYIelhq #EndTB pic.twitter.com/33G7sI8K2J
— World Health Organization (WHO) (@WHO) October 14, 2021
Former CDC director: Low sodium salt could save millions of lives.
15 Oct, 2021 | 02:27h | UTCFormer CDC director: Low sodium salt could save millions of lives – CNN
Related:
Is salt good for you after all? The evidence says no.
Systematic Review: Altered dietary salt intake for people with chronic kidney disease.
New WHO benchmarks help countries reduce salt intake and save lives.
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels
Systematic Review: There is not enough evidence from randomized trials to inform about the effects of additional antihypertensive drugs in patients with hypertension‐induced left ventricular hypertrophy.
15 Oct, 2021 | 02:20h | UTCPharmacotherapy for hypertension‐induced left ventricular hypertrophy – Cochrane Library
Commentary on Twitter
What are the effects of added #antihypertensive drug therapy on morbidity/mortality of people with #LVH and #hypertension? 💊
Our @CochraneLibrary @CochraneHTN systematic review looks at evidence from 3 RCTs w/ 930 participants with #highbloodpressure
👉🏾https://t.co/d3dakCPW0B pic.twitter.com/ppCqKBU7K0
— Cochrane Hypertension (@CochraneHTN) October 11, 2021
Meta-analysis of cohort studies: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death.
15 Oct, 2021 | 02:22h | UTCNews release: High intake of fatty acid in nuts, seeds and plant oils linked to lower risk of death – The BMJ
Commentaries:
Current evidence on dietary intakes of fatty acids and mortality – The BMJ
Commentary on Twitter
NEW research: A high intake of alpha linolenic acid, found mainly in nuts, seeds, and plant oils, is associated with a lower risk of death from all causes, and specifically from diseases of the heart and blood vessels, finds a study https://t.co/HGvg8dBUUN
— The BMJ (@bmj_latest) October 14, 2021
Trends in use and outcomes of same-day discharge following elective percutaneous coronary intervention.
15 Oct, 2021 | 02:15h | UTCTrends in Use and Outcomes of Same-Day Discharge Following Elective Percutaneous Coronary Intervention – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Commentaries:
Trends in Same-Day Discharge for Elective PCI – American College of Cardiology
M-A: Predictors of permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement.
15 Oct, 2021 | 02:19h | UTC
Commentary on Twitter
Meta-analysis of 78 studies identifies key predictors of pacemaker implantation after TAVR. https://t.co/EYFo1jWj5m #AHAJournals @vakasullah @fischman_david @TJUHospital @TJHeartFellows pic.twitter.com/eu7WbUoTGY
— JAHA (@JAHA_AHA) July 22, 2021
Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomized trials.
15 Oct, 2021 | 02:07h | UTC
Commentary on Twitter
https://twitter.com/NicoleKuderer/status/1423002503138795521
Cohort study: Among women with congenital Long QT, progestin oral contraceptives were linked to a 2.8-fold increased risk of cardiovascular events in those not receiving B-blocker therapy.
15 Oct, 2021 | 02:17h | UTCUse of oral contraceptives in women with congenital long QT syndrome – Heart Rhythm (link to abstract – $ for full-text)
Commentary: Progestin OCs Triple CV Events in Women With Congenital Long QT – TCTMD
Autoimmune encephalitis–related seizures and epilepsy: diagnostic and therapeutic approaches.
15 Oct, 2021 | 02:08h | UTC
Commentary on Twitter
Acute symptomatic seizure secondary to autoimmune encephalitis is a common symptom in patients with autoimmune encephalitis, particularly when the limbic system is involved.https://t.co/amUDoR8fXK pic.twitter.com/Fn0BFCbmhh
— Mayo Clinic Proceedings (@MayoProceedings) August 26, 2021
Ray Moynihan: Ten things I wish I’d been told as a junior academic.
15 Oct, 2021 | 02:13h | UTCRay Moynihan: Ten things I wish I’d been told as a junior academic – The BMJ Opinion
Intracerebral hemorrhage: diagnosis, emergency management, and prognosis.
15 Oct, 2021 | 02:12h | UTCIntracerebral Hemorrhage: Diagnosis, Emergency Management, and Prognosis – emDocs
How to be a good science communicator.
14 Oct, 2021 | 10:13h | UTCHow to be a good science communicator – Nature Medicine
Commentary on Twitter
During the COVID-19 pandemic, the public have turned to scientists and doctors for vital information. But science communication is a skill in itself, so we asked the experts to share their tips.
Feature from @polkajunctionhttps://t.co/eK2HYqs67m
— Nature Medicine (@NatureMedicine) October 13, 2021
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
14 Oct, 2021 | 10:15h | UTCCommentaries:
Most COVID-19 survivors have symptoms 6 months on, review finds – CIDRAP
How many people get ‘long COVID’? More than half, researchers find – Penn State
Related:
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Commentary on Twitter
Most #COVID19 survivors have symptoms 6 months on, review finds
Data on more than 250,000 survivors reveal 54% had at least 1 symptom 6 months or more after diagnosis #LongCovidhttps://t.co/xd0lvhQFfL pic.twitter.com/65mqe7SQPg
— CIDRAP (@CIDRAP) October 13, 2021
Video: Merck’s Covid pill could transform treatment. Here’s how it works.
14 Oct, 2021 | 10:10h | UTCWatch: Merck’s Covid pill could transform treatment. Here’s how it works – STAT
Related:
How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.
What we know — and don’t know — about Merck’s new Covid-19 pill.
Merck’s Covid-19 pill is great news but may not be a game-changer.
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
[Preprint] In RCT with 29,949 participants, the Novavax vaccine demonstrated high overall efficacy (>90%) for the prevention of Covid-19, and all moderate-to-severe cases occurred in placebo recipients.
14 Oct, 2021 | 10:17h | UTCEfficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico – medRxiv
Commentary: Novel vaccine demonstrates high efficacy for prevention of COVID-19 – News Medical
Related:
Opinion | The mRNA vaccines are extraordinary, but Novavax is even better.
RCT: Novavax vaccine is 49.4% effective against B.1.351 SARS-CoV-2 variant.
New COVID-19 vaccines: here’s how the promising Novavax and Johnson & Johnson jabs work
Covid-19: Novavax vaccine efficacy is 86% against UK variant and 60% against South African variant
Commentary on Twitter
Remember Novavax's #COVID vaccine?
Recent data looks really good.
~30K participants enrolled in a prospective clinical trial.
The vaccine appeared to be safe & effective (>90%).
Unclear why approval is taking so long.
Preprint 👉 https://t.co/MQkJXdgJyR pic.twitter.com/217Erw2stC
— Isaac Bogoch (@BogochIsaac) October 12, 2021
WHO provides guidance to address the shortage of quality palliative care services.
14 Oct, 2021 | 09:59h | UTCNews release: WHO takes steps to address glaring shortage of quality palliative care services – World Health Organization
See Guidance:
Commentary on Twitter (thread – click for more)
Today is World Hospice and Palliative Care Day!
DYK❓ Over 5⃣5⃣ million people around the 🌐 are in need of #PalliativeCare but only 12% of the global need is met.
Access to palliative care services is a human right to health 👉https://t.co/MebmzEstql pic.twitter.com/WQ3d40dH6d
— World Health Organization (WHO) (@WHO) October 9, 2021
How Covax failed on its promise to vaccinate the world – “Covax, described as “naively ambitious” by one expert, has contributed just 5% of all vaccines administered globally”.
14 Oct, 2021 | 10:12h | UTCHow Covax failed on its promise to vaccinate the world – The Bureau of Investigative Journalism
Related:
Perspective | A beautiful idea: how COVAX has fallen short.
WHO Launches Strategy to Achieve Global Covid-19 Vaccination by mid-2022.
WHO special envoys: To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe.
WHO COVAX Joint Statement: Call to action to equip COVAX to deliver 2 billion doses in 2021.
Covax: How will Covid vaccines be shared around the world?
Home Hemodialysis: Core Curriculum 2021.
14 Oct, 2021 | 09:55h | UTCHome Hemodialysis: Core Curriculum 2021 – American Journal of Kidney Diseases
Commentary on Twitter
Nephrologists and dialysis providers must embrace new technologies and improve their understanding of home hemodialysis systems. Review the benefits, pitfalls, and challenges of HHD in this Core Curriculum by @ScottDBieber and Bessie Young:https://t.co/TAPiH4wSIA (FREE) pic.twitter.com/dgeX0XKiuL
— AJKD (@AJKDonline) October 5, 2021