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Global Covid-19 deaths surpass five million.

2 Nov, 2021 | 02:59h | UTC

Global Covid-19 deaths surpass five million – CNN

See also:

The COVID-19 pandemic has now killed 5 million people around the world – NPR

G20 leaders back COVID measures as deaths top 5 million – CIDRAP

Covid-19 deaths pass five million worldwide – BBC

Related:

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Commentary on Twitter

 


Review: Infectious disease in an era of global change.

3 Nov, 2021 | 09:50h | UTC

Infectious disease in an era of global change – Nature Reviews Microbiology

 

Commentary on Twitter

 


In Covid-19 vaccinated people, those with prior infection are likely to have more antibodies.

2 Nov, 2021 | 03:03h | UTC

News release: In Covid-19 Vaccinated People, Those with Prior Infection Likely to Have More Antibodies – Johns Hopkins Medicine

Original Article: Durability of Antibody Levels After Vaccination With mRNA SARS-CoV-2 Vaccine in Individuals With or Without Prior Infection – JAMA

 


ASCO Guideline Update: Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.

2 Nov, 2021 | 02:51h | UTC

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update – Journal of Clinical Oncology

 


A comprehensive review of vascular complications in COVID-19.

2 Nov, 2021 | 03:01h | UTC

A comprehensive review of vascular complications in COVID-19 – Journal of Thrombosis and Thrombolysis

 


J&J Covid-19 vaccination is associated with increased risk of cerebral venous sinus thrombosis.

2 Nov, 2021 | 03:02h | UTC

Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination – JAMA

Commentary: Cerebral Venous Sinus Thrombosis Rate Up After Ad26.COV2.S Shot – HealthDay

 


Deaths in Children and Adolescents Associated With COVID-19 and MIS-C in the United States.

2 Nov, 2021 | 02:58h | UTC

Deaths in Children and Adolescents Associated With COVID-19 and MIS-C in the United States – Pediatrics

Related:

Thirty-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – “Despite negligible fatality, complications including hospitalization, hypoxemia, and pneumonia were more frequent in children and adolescents with COVID-19 than with influenza”.

Deaths from COVID ‘incredibly rare’ among children.

[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

 


Increased temperatures contributed to more than 200,000 cases of kidney disease in 15 years in Brazil alone.

2 Nov, 2021 | 02:46h | UTC

News release: Increased temperatures contributed to more than 200,000 cases of kidney disease in 15 years in Brazil alone, world’s largest study finds – Monash University

Original Study: Association between Ambient Temperature and Hospitalization for Renal Diseases in Brazil during 2000–2015: A Nationwide Case-Crossover Study – The Lancet Regional Health Americas

 


Study shows increased risk of Guillain-Barré syndrome following vaccination with recombinant zoster vaccine – “an attributable risk of 3 cases per million RZV (Shingrix) doses”.

2 Nov, 2021 | 02:45h | UTC

Risk of Guillain-Barré Syndrome Following Recombinant Zoster Vaccine in Medicare Beneficiaries – JAMA Internal Medicine (free for a limited period)

Related: FDA Requires a Warning about Guillain-Barré Syndrome (GBS) be Included in the Prescribing Information for Shingrix

 


Consensus Statement: Preoperative management of gastrointestinal and pulmonary medications.

2 Nov, 2021 | 02:53h | UTC

Preoperative Management of Gastrointestinal and Pulmonary Medications: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement – Mayo Clinic Proceedings

Related articles from Mayo Clinic Proceedings:

Consensus Statement: Preoperative management of endocrine, hormonal, and urologic medications

Consensus statement: Preoperative management of opioid and nonopioid analgesics

Perioperative evaluation and management of patients with diabetes, thyroid disease, and adrenal insufficiency. Use of insulin and noninsulin diabetic medications, management of hyper and hypothyroidism, and use of stress-dose corticosteroids are some of the subjects reviewed

Review: Preoperative Cardiac Risk Assessment

Review | Perioperative cardiac risk reduction in noncardiac surgery.

Systematic Review of Perioperative Cardiac Risk Prediction Indices

Review: Perioperative venous thromboembolism prophylaxis

 


Short Review: Metronidazole-induced neurotoxicity.

2 Nov, 2021 | 02:41h | UTC

Metronidazole-induced neurotoxicity – Canadian medical Association Journal

 

Commentary on Twitter

 


ASCO Guideline: Management of immune-related adverse events in patients treated with Chimeric Antigen Receptor T-Cell Therapy.

2 Nov, 2021 | 02:47h | UTC

Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline – Journal of Clinical Oncology

 


Short Review: Ketamine for the treatment of acute pain.

2 Nov, 2021 | 02:43h | UTC

Ketamine for the treatment of acute pain – Canadian Medical Association Journal

 

Commentary on Twitter

 


Observational study suggests a third dose of the Pfizer COVID-19 vaccine can prevent severe COVID-19-related outcomes, compared with only two doses received at least 5 months before.

31 Oct, 2021 | 20:14h | UTC

Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study – The Lancet

Invited Commentary: Boosters appear effective, but are they always needed? – The Lancet

 

Commentaries on Twitter

 


Study shows fully vaccinated individuals can still catch SARS-CoV-2 delta variant and efficiently transmit infection in household settings, including to fully vaccinated contacts.

31 Oct, 2021 | 20:16h | UTC

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study – The Lancet Infectious Diseases

Commentaries:

COVID vaccines effective but household transmission of delta a risk for 1 in 4 – Imperial College London

What is the vaccine effect on reducing transmission in the context of the SARS-CoV-2 delta variant? – The Lancet Infectious Diseases

CoVID-19 vaccines lower risk of infection with delta variant, but infection can still be passed on in household settings – the Lancet

COVID vaccines protect against Delta but don’t fully stop disease spread – CIDRAP

Covid: Double vaccinated can still spread virus at home – BBC

 

Commentary on Twitter

 


Editorial: Safety and efficacy of antivirals against SARS-CoV-2 – “we need evidence not optimism”.

31 Oct, 2021 | 20:11h | UTC

Safety and efficacy of antivirals against SARS-CoV-2 – The BMJ

 

Commentary on Twitter

 


CDC Study: COVID-19 vaccine associated with 5 times the protection of ‘natural immunity’.

31 Oct, 2021 | 20:09h | UTC

Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19–Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity — Nine States, January–September 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

COVID-19 vaccine gives 5 times the protection of ‘natural immunity,’ data show – CIDRAP

COVID shots more protective than past infection, study shows – Associated Press

 

Commentary on Twitter

 


Cohort Study: Among patients with ST-segment elevation myocardial infarction, a concomitant Covid-19 diagnosis is associated with increased in-hospital mortality.

31 Oct, 2021 | 20:10h | UTC

Association Between COVID-19 Diagnosis and In-Hospital Mortality in Patients Hospitalized With ST-Segment Elevation Myocardial Infarction – JAMA

Editorial: Myocardial Infarction During the COVID-19 Pandemic – JAMA

Commentary: STEMI and COVID-19 Often a Lethal Combo, Affirms Largest Study Yet – TCTMD

 

Commentary from the author on Twitter (thread – click for more)

 


Opinion | Is Moderna really better than Pfizer—or is it just a higher dose?

31 Oct, 2021 | 20:06h | UTC

Is Moderna Really Better Than Pfizer—Or Is It Just a Higher Dose? – The Atlantic

Related: CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.

 

Commentary on Twitter

 


NICE Guideline | Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management.

31 Oct, 2021 | 20:03h | UTC

Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management – National Institute for Health and Care Excellence

Commentaries:

Chronic fatigue syndrome advice scraps exercise therapy – BBC

ME exercise therapy guidance scrapped by health watchdog Nice – The Guardian

 


RCT: Targeting higher intraoperative blood pressures does not reduce adverse cardiovascular events following noncardiac surgery.

31 Oct, 2021 | 20:00h | UTC

Targeting Higher Intraoperative Blood Pressures Does Not Reduce Adverse Cardiovascular Events Following Noncardiac Surgery – Journal of the American College of Cardiology

 


Cardiovascular clinical examination: the need for an evidence-based approach.

31 Oct, 2021 | 19:57h | UTC

Cardiovascular clinical examination: the need for an evidence-based approach – European Heart Journal

 

Commentary on Twitter

 


Study suggests smoking cessation, but not reduction, is associated with reduced risk of cardiovascular disease.

31 Oct, 2021 | 19:59h | UTC

Smoking cessation, but not reduction, reduces cardiovascular disease incidence – European Heart Journal (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Review: Clinical management of pancreatic premalignant lesions.

31 Oct, 2021 | 19:56h | UTC

Clinical Management of Pancreatic Premalignant Lesions – Gastroenterology

 


Imaging of congenital lung diseases presenting in the adulthood: a pictorial review.

31 Oct, 2021 | 19:53h | UTC

Imaging of congenital lung diseases presenting in the adulthood: a pictorial review – Insights into Imaging

 


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