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RCT: Subcutaneous Tirzepatide added to titrated Insulin Glargine improves glycemic control in patients with Type 2 Diabetes.

10 Feb, 2022 | 10:00h | UTC

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Tirzepatide for Patients With Type 2 Diabetes – JAMA

Commentary: SURPASS-5 Data: Tirzepatide Plus Insulin Glargine Improve Glycemic Control in T2D – AJMC

Related:

RCT: In patients with Type 2 Diabetes, Tirzepatide is associated with reduced weight, improved glycemic control, and lower risk of hypoglycemia compared to insulin glargine.

RCT: Once-weekly tirzepatide vs. once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes.

RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.

RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.

 


2021 Brazilian Thoracic Association recommendations for the management of severe asthma.

10 Feb, 2022 | 08:52h | UTC

2021 Brazilian Thoracic Association recommendations for the management of severe asthma – Jornal Brasileiro de Pneumologia

 


Position statement on the care of the athlete and athletic person with diabetes.

10 Feb, 2022 | 08:49h | UTC

American Medical Society for Sports Medicine Position Statement on the Care of the Athlete and Athletic Person With Diabetes – Clinical Journal of Sport Medicine

 


M-A: In patients with acute coronary syndrome undergoing percutaneous coronary intervention, short duration of dual antiplatelet therapy (DAPT) was comparable to de-escalation regarding all-cause death. De-escalation reduced the risk for adverse cardiovascular events, while short DAPT decreased major bleeding.

10 Feb, 2022 | 08:46h | UTC

Short Duration of DAPT Versus De-Escalation After Percutaneous Coronary Intervention for Acute Coronary Syndromes – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: Short Duration of DAPT vs. De-Escalation After PCI for ACS – American College of Cardiology

 


GOLD Report 2022: Global strategy for prevention, diagnosis and management of COPD.

10 Feb, 2022 | 08:53h | UTC

GOLD Report 2022: Global strategy for prevention, diagnosis and management of COPD

 


Systematic Review: Overuse of diagnostic testing in healthcare.

10 Feb, 2022 | 08:47h | UTC

Overuse of diagnostic testing in healthcare: a systematic review – BMJ Quality & Safety

 


Culprit medications and risk factors associated with Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A population-based nested case–control study.

10 Feb, 2022 | 08:42h | UTC

Culprit Medications and Risk Factors Associated with Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Population-Based Nested Case–Control Study – American Journal of Clinical Dermatology

 


M-A: Time to benefit for stroke reduction after blood pressure treatment in older adults.

10 Feb, 2022 | 08:44h | UTC

Time to benefit for stroke reduction after blood pressure treatment in older adults: A meta-analysis – Journal of the American Geriatrics Society

News Release: New research finds more intensive blood pressure treatment may prevent strokes in older adults – Wiley

 


Primer for artificial intelligence in primary care.

10 Feb, 2022 | 08:36h | UTC

Primer for artificial intelligence in primary care – Canadian Family Physician

Editorial: Artificial intelligence and the family physician

 


Medication management for heart failure with reduced ejection fraction: Clinical pearls for optimizing evidenced-informed therapy.

10 Feb, 2022 | 08:41h | UTC

Medication management for heart failure with reduced ejection fraction – Canadian Family Physician

 


Guide to writing and publishing a scientific manuscript: Part 1—The structure.

10 Feb, 2022 | 08:35h | UTC

Guide to writing and publishing a scientific manuscript: Part 1—The structure – Canadian Journal of Emergency Medicine

 


Short Review: Biologics for episodic and chronic migraines.

10 Feb, 2022 | 08:40h | UTC

Biologics for episodic and chronic migraines – Canadian Family Physician

 


Perioperative approach to precapillary pulmonary hypertension in non-cardiac non-obstetric surgery.

10 Feb, 2022 | 08:34h | UTC

Perioperative approach to precapillary pulmonary hypertension in non-cardiac non-obstetric surgery – European Respiratory Review

 


Review: Cognitive-behavioural therapy for children with irritable bowel syndrome.

10 Feb, 2022 | 08:38h | UTC

Cognitive-behavioural therapy for children with irritable bowel syndrome – Canadian Family Physician

 


Abemaciclib with endocrine therapy in the treatment of high-risk early breast cancer: ASCO optimal adjuvant chemotherapy and targeted therapy guideline rapid recommendation update.

10 Feb, 2022 | 08:33h | UTC

Abemaciclib With Endocrine Therapy in the Treatment of High-Risk Early Breast Cancer: ASCO Optimal Adjuvant Chemotherapy and Targeted Therapy Guideline Rapid Recommendation Update – Journal of Clinical Oncology

 


Interstitial pneumonia with autoimmune features: challenges and controversies.

10 Feb, 2022 | 08:33h | UTC

Interstitial pneumonia with autoimmune features: challenges and controversies – European Respiratory Review

 


M-A: Patients generally may return to driving 4 weeks after hip arthroscopy and 6 weeks after knee arthroscopy.

10 Feb, 2022 | 08:31h | UTC

Patients Generally May Return to Driving 4 Weeks After Hip Arthroscopy and 6 Weeks After Knee Arthroscopy: A Systematic Review and Meta-analysis – Arthroscopy, Sports Medicine, and Rehabilitation

 

Commentary on Twitter

 


RCT: Apatinib improves outcomes compared to placebo in patients with locally advanced or metastatic, radioactive iodine–refractory differentiated thyroid cancer.

10 Feb, 2022 | 09:56h | UTC

Apatinib vs Placebo in Patients With Locally Advanced or Metastatic, Radioactive Iodine–Refractory Differentiated Thyroid Cancer: The REALITY Randomized Clinical Trial – JAMA Oncology

 

Commentary on Twitter

 


RCT: Home phototherapy of term neonates improves parental bonding and stress.

10 Feb, 2022 | 08:25h | UTC

Home phototherapy of term neonates improves parental bonding and stress: Findings from a randomised controlled trial – Acta Paediatrica

 

Commentary on Twitter

 


M-A: Pain management in acute pancreatitis.

10 Feb, 2022 | 08:29h | UTC

Pain Management in Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomised Controlled Trials – Frontiers in Medicine

 


Opinion: Development of clinical practice guidelines ‘is a mess’.

9 Feb, 2022 | 10:16h | UTC

Development of clinical practice guidelines ‘is a mess’ – STAT

 


Recommendations for management of childhood psoriasis.

10 Feb, 2022 | 08:26h | UTC

Recommendations for management of childhood psoriasis – Indian Dermatology Online Journal

 


IDSA Updated Covid-19 Guideline now supports the use of convalescent plasma in ambulatory patients with mild to moderate COVID-19 at high risk for progression to severe disease.

9 Feb, 2022 | 10:15h | UTC

IDSA Guidelines on the Treatment and Management of Patients with COVID-19 – Infectious Diseases Society of America

Related: [Preprint] RCT: In symptomatic adults above 18 years positive for SARS-CoV-2, early outpatient treatment with high-titer convalescent plasma significantly reduced hospitalizations.

 

Commentary on Twitter

 


European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

9 Feb, 2022 | 10:18h | UTC

European Society of clinical microbiology and infectious diseases (ESCMID) guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli (endorsed by ESICM –European Society of intensive care Medicine) – Clinical Microbiology and Infection

Related: IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

 


WHO: Two years into COVID pandemic, most countries still face significant health service disruptions.

9 Feb, 2022 | 10:13h | UTC

Two Years into COVID Pandemic, Most Countries Still Face Significant Health Service Disruptions – Health Policy Watch

Original Report: Third round of the global pulse survey on continuity of essential health services during the COVID-19 pandemic – World Health Organization

 


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