Archives
Diet and irritable bowel syndrome: an update from a UK consensus meeting.
19 Sep, 2022 | 12:42h | UTCDiet and irritable bowel syndrome: an update from a UK consensus meeting – BMC Medicine
Related:
M-A | Efficacy of a restrictive diet in irritable bowel syndrome.
10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.
Supplement: Irritable bowel syndrome and related conditions.
RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
Guidelines for the treatment of irritable bowel syndrome
ACG Clinical Guideline: Management of irritable bowel syndrome
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
AAP Policy Statement | Helmet use in preventing head injuries in bicycling, snow sports, and other recreational activities and sports.
19 Sep, 2022 | 12:43h | UTCTechnical Report: Helmet Use in Preventing Head Injuries in Bicycling, Snow Sports, and Other Recreational Activities and Sports – Pediatrics
Commentary: Multifaceted Approach Urged for Promoting Helmet Use for Children – HealthDay
RCT | Open-source automated insulin delivery in Type 1 Diabetes.
19 Sep, 2022 | 12:41h | UTCOpen-Source Automated Insulin Delivery in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Video summary: Open-Source Automated Insulin Delivery in Type 1 Diabetes – NEJM
Commentaries:
Automated Insulin Delivery Ups Time in Target Glucose Range in T1D – HealthDay
RCT | Methotrexate may increase response rates in patients with uncontrolled gout receiving Pegloticase.
19 Sep, 2022 | 12:38h | UTCCommentary: Data Now Out for Pegloticase-MTX Combo Gout Treatment – MedPage Today (free registration required)
Systematic Review | Debulking hysterectomy followed by chemoradiotherapy vs. chemoradiotherapy alone for women with locally advanced cancer of the cervix – not enough evidence to guide recommendations.
19 Sep, 2022 | 12:39h | UTC
M-A of randomized trials | Transanal tube vs. defunctioning stoma after low anterior resection for rectal cancer.
19 Sep, 2022 | 12:37h | UTC
M-A | Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide.
19 Sep, 2022 | 12:36h | UTC
RCT | Olokizumab, a monoclonal antibody against interleukin-6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by tumor necrosis factor inhibitor therapy.
19 Sep, 2022 | 12:35h | UTC
M-A of randomized trials | Ondansetron vs. Metoclopramide for managing hyperemesis gravidarum.
19 Sep, 2022 | 12:34h | UTCCommentary: Ondansetron or metoclopramide, which is better for managing hyperemesis gravidarum? – Medical Dialogues
The risk of subsequent surgery following bowel resection for Crohn’s disease in a national cohort of 19,207 patients.
19 Sep, 2022 | 12:33h | UTCThe risk of subsequent surgery following bowel resection for Crohn’s disease in a national cohort of 19,207 patients – Colorectal Disease (link to abstract – $ for full-text)
Commentary: Investigators Assess Risk of Further Surgery for Crohn’s Disease Patients – HCPLive
RCT | Intensity-modulated radiotherapy vs. stereotactic body radiotherapy for prostate cancer.
19 Sep, 2022 | 12:31h | UTCIntensity-modulated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): 2-year toxicity results from an open-label, randomised, phase 3, non-inferiority trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary from the author on Twitter (thread – click for more)
My first Tweetorial 🧵 2 year toxicity results of PACE B published here. Big thanks to the 🇬🇧🇨🇦 and🇮🇪collaborators and the 874 men with prostate cancer who made this trial possible https://t.co/mERz2ox8TM
— Alison Tree 💙 (@alison_tree) September 14, 2022
Phase 2 RCT | Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma.
19 Sep, 2022 | 12:32h | UTCCombined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial – The Lancet (free registration required for full-text)
ASCO Rapid Recommendation | Systemic therapy update on 177Lutetium-PSMA-617 for metastatic castration-resistant prostate cancer.
19 Sep, 2022 | 12:31h | UTC
Review | Aerosol delivery of lung surfactant and nasal CPAP in the treatment of neonatal respiratory distress syndrome.
19 Sep, 2022 | 12:29h | UTC
Nutrition assessment and management in patients with cirrhosis and cognitive impairment: a comprehensive review of literature.
19 Sep, 2022 | 12:29h | UTCCommentary: Review Outlines Nutrition Assessment, Management in Patients With Cirrhosis – AJMC
The Lancet Commission on lessons for the future from the COVID-19 pandemic – “a massive global failure.”
16 Sep, 2022 | 13:03h | UTCHomepage: The Lancet COVID-19 Commission
The Lancet Commission on lessons for the future from the COVID-19 pandemic
Editorial: COVID-19: the case for prosociality
Infographic: COVID-19 response: a massive global failure
Commentaries:
WHO responds to The Lancet COVID-19 Commission – World Health Organization
Covid-19: Commission describes “massive global failures” of pandemic response – The BMJ
Lancet Commission on COVID-19 response: ‘Massive global failure’ – CIDRAP
Update | Management of hepatorenal syndrome in liver cirrhosis.
19 Sep, 2022 | 12:27h | UTC
Guideline Synopsis | AHA/ACC Guideline for the management of heart failure.
16 Sep, 2022 | 13:01h | UTCManagement of Heart Failure – JAMA (free for a limited period)
Original Article: #ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.
The Lancet Commission | Towards the elimination of chronic obstructive pulmonary disease.
16 Sep, 2022 | 13:02h | UTCHomepage: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission – The Lancet
Commission: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission
Editorial: COPD: from an end-stage disease to lifelong lung health
Invited Commentary: Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD
Commentary: Proposed classification of COPD according to major risk factors – News Medical
AHA Scientific Statement | Management of patients at risk for and with left ventricular thrombus.
16 Sep, 2022 | 13:00h | UTC
RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).
16 Sep, 2022 | 12:59h | UTCEfficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary: Dutch team devise less painful ‘drip and drink’ antibiotics treatment for babies – Dutch News
Commentaries on Twitter
*New trial*—early switch to #OralAntibiotics is not inferior to full-course IV antibiotics in #neonates with probable bacterial infection; & adverse events were not increased with use of oral antibiotics
By @IKMReiss @karelallegaert & colleagues
https://t.co/2yzeh3ptuc pic.twitter.com/BgBosxfECC
— The Lancet Child & Adolescent Health (@LancetChildAdol) September 12, 2022
In term and near-term infants <28 days with probable bacterial infection, how safe is it to switch to oral Amox-Clav as opposed to completing a course of intravenous antibiotics? A new RCT in @Lancet tries to answer this question.https://t.co/M2Za54cfxF#EBNeoAlerts#NeoEBM pic.twitter.com/zKpIiW1Whx
— Evidence-Based Neo (@EBNEO) September 12, 2022
(Thread – click for more)
Efficacy & safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) vs full course of IV antibiotics in neonates with probable bacterial infection (RAIN):multicentre, randomised,open-label,non-inferiority trial -The Lancet https://t.co/mcyr9bILRq
— Prof. Dr. Sanjeev Bagai (@BagaiDr) September 13, 2022
Study | The specificity and positive predictive value of high-sensitivity cardiac troponin I for the diagnosis of myocardial infarction are reduced in older individuals.
16 Sep, 2022 | 12:57h | UTCInfluence of Age on the Diagnosis of Myocardial Infarction – Circulation
RCT | Short-term outcomes of laparoscopy-assisted vs. open surgery for patients with low rectal cancer.
16 Sep, 2022 | 12:58h | UTC
Commentary on Twitter
https://twitter.com/JAMAOnc/status/1570532915393744896
Consensus Statement | How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases.
16 Sep, 2022 | 12:56h | UTC
Transesophageal echocardiography in the emergency department: a comprehensive guide for acquisition, implementation, and quality assurance.
16 Sep, 2022 | 12:54h | UTC