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Reducing brain injury following cardiopulmonary resuscitation

11 May, 2017 | 18:43h | UTC

Practice guideline summary: Reducing brain injury following cardiopulmonary resuscitation (link to abstract – free PDF available)

Sources: Guideline: Offer Cooling After Cardiac Arrest – MedPage Today (free) AND Body Cooling Recommended for Some Comatose Patients After Cardiac Arrest – Physician’s First Watch (free)

 


Vector control: time for a planetary health approach

12 May, 2017 | 19:26h | UTC

Editorial: Vector control: time for a planetary health approach – The Lancet Global Health (free)

 


Hodgkin Lymphoma – NCCN Clinical Practice Guidelines

12 May, 2017 | 19:31h | UTC

Hodgkin Lymphoma Version 1.2017, NCCN Clinical Practice Guidelines in Oncology (free)

 


Fri, May 12 – 10 Medical Stories of The Day!

12 May, 2017 | 00:01h | UTC

 

1 – Arthroscopic surgery for degenerative knee arthritis and meniscal tears: a clinical practice guideline – The BMJ (free)

Commentaries: This orthopedic surgery is the world’s most common. But patients rarely benefit, a panel says – STAT News (free) AND Guideline Recommends Against Arthroscopy for Most Cases of Degenerative Knee Disease – Journal Watch (free) AND Arthroscopic Surgery Doesn’t Help With Arthritis Knee Pain – NPR Health News (free)

 

2 – Internet-Based Vestibular Rehabilitation for Older Adults With Chronic Dizziness: A Randomized Controlled Trial in Primary Care – Annals of Family Medicine (free)

See also: Balance retraining tool used in the study (free)

Commentaries: Online Rehabilitation Program Reduces Chronic Dizziness – Medscape (free registration required) AND Online Intervention Could Reduce Chronic Dizziness – Physician’s First Watch (free)

 

3 – Can Endgame Tobacco radically reduce cigarette smoking? – Healthy Debate (free) (RT @IrfanDhalla see Tweet)

Related: The tobacco endgame: a qualitative review and synthesis – Tobacco Control (free) AND It’s time to focus on an endgame for tobacco regulation – The Conversation (free)

“The “Tobacco Endgame” concept moves thinking away from the mere control of tobacco towards plans for ending the tobacco pandemic, and foresees a tobacco-free future” (from The Conversation)

 

4 – Review: Countering cognitive biases in minimizing low value care – The Medical Journal of Australia (free)

“How cognitive bias affects clinical decision making and what to do about it. Well written & useful” (RT @carissa_bon and @JulieLeask see Tweet)

 

5 – Using AI to Detect Cancer, Not Just Cats – Wired (free) (RT @EricTopol see Tweet)

Related: Is AI a threat or benefit to health workers? – CMAJ News (free)

More on Artificial Intelligence in Healthcare in our April 28Th issue (see #1) and in our April 10th issue (see #8)

 

6 – NCCN Guidelines Insights: Hepatobiliary Cancers, Version 1.2017 (free)

 

7 – Hodgkin Lymphoma Version 1.2017, NCCN Clinical Practice Guidelines in Oncology (free)

 

8 – Enhanced Recovery After Surgery Program Implementation in 2 Surgical Populations in an Integrated Health Care Delivery System – JAMA Surgery (free)

Invited commentary: Enhanced Surgical Recovery Through Enhanced Research From Integrated Health Systems (free)

See also our selection of Enhanced Recovery After Surgery Free Guidelines and Reviews

In this pre-post difference-in-differences study with 20 medical centers and 15849 surgical patients, implementation of ERAS protocols in patients undergoing elective colorectal resection and patients undergoing emergency hip fracture repair were associated with decreases in hospital length of stay and postoperative complication rates.

 

9 – Editorial: Vector control: time for a planetary health approach – The Lancet Global Health (free)

 

10 – Socioeconomic status as an effect modifier of alcohol consumption and harm: analysis of linked cohort data – The Lancet Public Health (free)

Invited commentary: Socioeconomic status and susceptibility to alcohol-related harm (free)

Commentary: Poorest at greater risk from heavy drinking, says study – BBC (free)

 


Improved life expectancy of people living with HIV

11 May, 2017 | 18:39h | UTC

Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies – The Lancet HIV (free)

Invited commentary: Improved life expectancy of people living with HIV: who is left behind? (free)

Source: Treatment now gives some HIV patients a normal life expectancy, study finds – STAT News (free)

 


Multidrug-resistant tuberculosis in India, the Philippines, Russia, and South Africa

11 May, 2017 | 18:41h | UTC

Estimating the future burden of multidrug-resistant and extensively drug-resistant tuberculosis in India, the Philippines, Russia, and South Africa: a mathematical modelling study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentaries: Drug Resistant TB Is Predicted To Steadily Spread In 4 Countries – NPR Goats and Soda (free) AND The Deadliest Form Of Tuberculosis Is Snowballing In Countries That Are Already Hard Hit – Huffington Post (free) AND Researchers Predict Increase in Drug-resistant TB – VOA News (free) AND Drug-resistant tuberculosis strains gain foothold – Science (free)

See also our coverage of #WorldTBDay in our March 24th issue

 


Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Coronary Narrowing

11 May, 2017 | 18:37h | UTC

Meta-Analysis of Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Coronary Narrowing – Journal of The American College of Cardiology (link to abstract – $ for full-text) (source: EvidenceAlerts)

Related recent meta-analysis: Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials – Circulation: Cardiovascular Interventions (free) AND Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis – BMC Medicine (free)

PCI with drug-eluding stents seems to be a safe alternative to CABG in Unprotected Left Main Coronary Artery Stenosis, but it is associated with higher rates of repeat revascularization.


Risk of acute myocardial infarction with NSAIDs

11 May, 2017 | 18:38h | UTC

Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data – The BMJ (free)

Commentaries: Meta-Analysis: Just a Week of NSAID Use Tied to Increased Heart Attack Risk – Journal Watch (free) AND Common painkillers linked to increased risk of heart attack, study says – CNN (free) All NSAIDs Linked to Increased MI Risk – Medscape (free registration required)

Another study suggesting NSAIDs may be associated with increased cardiovascular risk.

 


Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline

11 May, 2017 | 18:35h | UTC

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline (free)

Source: Urologic Groups Offer New Prostate Cancer Management Guideline – Physician’s First Watch (free)

 


Ten Principles of Good Prescribing

11 May, 2017 | 18:42h | UTC

Ten Principles of Good Prescribing – by J K Aronson, Centre for Evidence-Based Medicine (CEBM) (free)

 


Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality

10 May, 2017 | 18:27h | UTC

Meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)

Source: Eating cheese does not raise risk of heart attack or stroke, study finds – The Guardian (free)

Dairy seems to be neutral regarding risks of cardiovascular diseases and all-cause mortality.

 


How To Do A Really Good Job Washing Your Hands

11 May, 2017 | 18:36h | UTC

How To Do A Really Good Job Washing Your Hands – NPR Health News (free)

See also World Health Organization and Centers for Disease Control and Prevention (CDC) “Clean Hands” campaigns in our May 5th issue, see #2.

 


Guidelines for the management of gastrointestinal stromal tumours (GIST)

10 May, 2017 | 18:25h | UTC

UK clinical practice guidelines for the management of gastrointestinal stromal tumours (GIST) – Clinical Sarcoma Research (free)

 


Mortality from different causes associated with meat, heme iron, nitrates, and nitrites

10 May, 2017 | 18:28h | UTC

Meta-analysis: Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study – The BMJ (free)

High intakes of red and processed meat are associated with increased risks of all-cause mortality and death due to nine different causes.

 


Screening for Thyroid Cancer: USPSTF Recommendation Statement

10 May, 2017 | 18:29h | UTC

Screening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)

Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)

Editorial 3: How to Look for Thyroid Cancer (free)

Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)

The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).

 


Intravenous fluid therapy in adults in hospital – NICE Guideline

9 May, 2017 | 20:45h | UTC

Intravenous fluid therapy in adults in hospital – Updated National Institute for Health and Care Excellence (NICE – UK) Guideline (free)

 


Guideline for opioid therapy and chronic noncancer pain

10 May, 2017 | 18:26h | UTC

Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)

 


One-Third Of New Drugs Had Safety Problems After FDA Approval

10 May, 2017 | 18:22h | UTC

Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010 – JAMA (link to abstract – $ for full-text)

Commentaries: Nearly 1 In 3 Recent FDA Drug Approvals Followed By Major Safety Actions – Scientific American (free) AND One in Three Newly Approved Drugs Has Safety Issues – MedPage Today (free registration required) AND Safety Events Common in Newly Approved Drugs – Medscape(free registration required) AND New safety risks detected in one-third of FDA-approved drugs – The Washington Post (free) (RT @EricTopol see Tweet) AND One-Third Of New Drugs Had Safety Problems After FDA Approval – NPR Health News (free)

*Newer is not always better.

 


Thu, May 11 – 10 Medical Stories of The Day!

11 May, 2017 | 00:15h | UTC

 

1 – Practice guideline summary: Reducing brain injury following cardiopulmonary resuscitation (link to abstract – free PDF available)

Sources: Guideline: Offer Cooling After Cardiac Arrest – MedPage Today (free) AND Body Cooling Recommended for Some Comatose Patients After Cardiac Arrest – Physician’s First Watch (free)

 

2 – Ten Principles of Good Prescribing – by J K Aronson, Centre for Evidence-Based Medicine (CEBM) (free)

 

3 – Estimating the future burden of multidrug-resistant and extensively drug-resistant tuberculosis in India, the Philippines, Russia, and South Africa: a mathematical modelling study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentaries: Drug Resistant TB Is Predicted To Steadily Spread In 4 Countries – NPR Goats and Soda (free) AND The Deadliest Form Of Tuberculosis Is Snowballing In Countries That Are Already Hard Hit – Huffington Post (free) AND Researchers Predict Increase in Drug-resistant TB – VOA News (free) AND Drug-resistant tuberculosis strains gain foothold – Science (free)

See also our coverage of #WorldTBDay in our March 24th issue

 

4 – Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies – The Lancet HIV (free)

Invited commentary: Improved life expectancy of people living with HIV: who is left behind? (free)

Source: Treatment now gives some HIV patients a normal life expectancy, study finds – STAT News (free)

 

5 – Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data – The BMJ (free)

Commentaries: Meta-Analysis: Just a Week of NSAID Use Tied to Increased Heart Attack Risk – Journal Watch (free) AND Common painkillers linked to increased risk of heart attack, study says – CNN (free) All NSAIDs Linked to Increased MI Risk – Medscape (free registration required)

Another study suggesting NSAIDs may be associated with increased cardiovascular risk.

 

6 – Meta-Analysis of Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Coronary Narrowing – Journal of The American College of Cardiology (link to abstract – $ for full-text) (source: EvidenceAlerts)

Related recent meta-analysis: Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials – Circulation: Cardiovascular Interventions (free) AND Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis – BMC Medicine (free)

PCI with drug-eluding stents seems to be a safe alternative to CABG in Unprotected Left Main Coronary Artery Stenosis, but it is associated with higher rates of repeat revascularization.

 

7 – How To Do A Really Good Job Washing Your Hands – NPR Health News (free)

See also World Health Organization and Centers for Disease Control and Prevention (CDC) “Clean Hands” campaigns in our May 5th issue, see #2.

 

8 – Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline (free)

Source: Urologic Groups Offer New Prostate Cancer Management Guideline – Physician’s First Watch (free)

 

9 – Antibiotic Prescribing for Nonbacterial Acute Upper Respiratory Infections in Elderly Persons – Annals of Internal Medicine (link to abstract – $ for full-text)

Source: Half of all seniors who went to doctor for common cold prescribed unnecessary antibiotics – Science Magazine (free)

 

10 – Review: Current Trends in the Management of Gastroesophageal Reflux Disease – Gut and Liver (free PDF)

 


Approach to the Patient with Hematochezia

9 May, 2017 | 20:43h | UTC

Review: Approach to the Patient with Hematochezia – Mayo Clinic Proceedings (free) (RT @HMVJC)

 


Guideline for the Management of Fever and Neutropenia in Children

10 May, 2017 | 18:24h | UTC

Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)

 


Noncommunicable diseases: the slow-motion disaster

9 May, 2017 | 18:21h | UTC

Noncommunicable diseases: the slow-motion disaster – World Health Organization (free)

Related WHO resources: Other dimensions of the NCD crisis: from mental health, ageing, dementia and malnutrition to deaths on the roads, violence and disability (free) AND Tools for implementing WHO PEN (Package of essential noncommunicable disease interventions) (free) AND WHO’s work on NCDs (free)

Source: Noncommunicable Diseases: A Global ‘Slow-Motion Disaster’ – Medscape (free registration required)

 


Type 2 diabetes in adults: management – NICE Guideline

9 May, 2017 | 20:44h | UTC

Type 2 diabetes in adults: management – Updated National Institute for Health and Care Excellence (NICE – UK) Guideline (free)

 


Wed, May 10 – 10 Medical Stories of The Day!

10 May, 2017 | 00:01h | UTC

 

1 – Screening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)

Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)

Editorial 3: How to Look for Thyroid Cancer (free)

Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)

The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).

 

2 – Meta-analysis: Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study – The BMJ (free)

High intakes of red and processed meat are associated with increased risks of all-cause mortality and death due to nine different causes.

 

3 – Meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)

Source: Eating cheese does not raise risk of heart attack or stroke, study finds – The Guardian (free)

Dairy seems to be neutral regarding risks of cardiovascular diseases and all-cause mortality.

 

4 – Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)

 

5 – UK clinical practice guidelines for the management of gastrointestinal stromal tumours (GIST) – Clinical Sarcoma Research (free)

 

6 – Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)

 

7 – Viewpoint: Business Model–Related Conflict of Interests in Medicine: Problems and Potential Solutions – JAMA (free)

Source: Doctors should be paid by salary, not fee-for-service, argue behavioral economists – EurekAlert (free)

 

8 – Insights: Finding the Rare Pathogenic Variants in a Human Genome – JAMA (free)

“Prudent perspective on whole genome sequencing for healthy individuals” (RT @EricTopol see Tweet)

Technology allows sequencing of the entire human genome, but for healthy people, it currently has no clear clinical benefit and is inconsistent with a fundamental clinical axiom—to refrain from seeking uninterpretable and misleading information in patients or healthy individuals” .

 

9 – First opinion: The shadow of Big Tobacco looms over e-cigarettes and harm reduction – STAT News (free)

“Should we settle for lesser harms?”. “Examples of harm reduction strategies include providing methadone to heroin users… opening needle exchanges to prevent the spread of HIV and hepatitis among individual who inject drugs…and promoting e-cigarettes or smokeless tobacco as alternatives to smoking combustible cigarettes”.

 

10 – Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010 – JAMA (link to abstract – $ for full-text)

Commentaries: Nearly 1 In 3 Recent FDA Drug Approvals Followed By Major Safety Actions – Scientific American (free) AND One in Three Newly Approved Drugs Has Safety Issues – MedPage Today (free registration required) AND Safety Events Common in Newly Approved Drugs – Medscape (free registration required) AND New safety risks detected in one-third of FDA-approved drugs – The Washington Post (free) (RT @EricTopol see Tweet) AND One-Third Of New Drugs Had Safety Problems After FDA Approval – NPR Health News (free)

*Newer is not always better.

 


Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes

9 May, 2017 | 18:17h | UTC

Review: Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes – Circulation Research (free)

 


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