Archives
Mon, May 29 – 10 Medical Stories of The Day!
29 May, 2017 | 00:01h | UTC
1 – Preparing for the next WHO Campaign: World No Tobacco Day, 31 May 2017 – World Health Organization (free infographics, posters, banners, publications and other resources for the upcoming campaign)
See also: “Tobacco Endgame” policies in our May 12th issue, see #3.
See also: Smoking prevalence and attributable disease burden in 195 countries and territories in our April 7th issue, see #1.
“Wednesday 31 May is World No Tobacco Day. Tweet using #NoTobacco “Protect health, reduce poverty, promote development” (RT @gmacscotland see Tweet)
2 – Type 2 diabetes in adults: management – NICE Guideline (free)
See also: Algorithm for blood glucose lowering therapy in adults with type 2 diabetes (free PDF)
Source: UK NICE Elevates SGLT2 Inhibitors in Diabetes Guidance – Medscape (free registration required)
3 – Viewpoint: Direct-to-Consumer Medical Testing in the Era of Value-Based Care – JAMA (free)
See also a recent discussion on direct-to-consumer genetic testing in our April 10th issue, see #5
Others disagree: “Dissing every consumer medical test as “low value”. Sorry, that’s not true. It’s called paternalism” (RT @EricTopol see Tweet)
4 – The Weight Loss Trap: Why Your Diet Isn’t Working – Time (cover story) (free)
“The challenges of weight loss and obesity – really well addressed” (RT @EricTopol see Tweet)
Commentary: Several non-drug options help with fatigue during, after cancer treatment – Reuters Health News (free)
6 – Countries like German and Italy are adopting mandatory vaccination policies
Germany vaccination: Fines plan as measles cases rise – BBC Health News (free) AND German kindergartens must report parents for refusing vaccine advice under new law – Reuters Health News (free)
See also: Italy makes 12 vaccinations compulsory for children and related commentaries in our May 22nd issue, see #2.
7 – #ATS2017 – Antibiotic therapy for nearly one in four adults with pneumonia does not work – American Thoracic Society, via Science Daily (free) (RT @IDSAInfo see Tweet)
See also: Pneumonia Treatment Failure Rates High – Medscape (free registration required) AND Adults With Pneumonia Often Fail First Antibiotic – MedPage Today (free registration required)
8 – Clinical relevance of thrombocytosis in primary care: a prospective cohort study of cancer incidence using English electronic medical records and cancer registry data – British Journal of General Practice (link to abstract – $ for full-text)
Commentaries: Cautions and caveats help buoy Guardian story on using high platelet count for cancer detection – HealthNewsReview (free) High blood platelet count ‘as good a cancer predictor as a lump in the breast’ – The Guardian (free)
Thrombocytosis seems to be a risk marker of cancer in adults, but questions remain about the clinical usefulness of these findings.
9 – New Guideline Summaries – National Guideline Clearinghouse (US):
1 – Systemic therapy of incurable gastroenteropancreatic neuroendocrine tumours – Cancer Care Ontario (free) AND 2 – Guidelines for the management of severe traumatic brain injury, 4th edition – Brain Trauma Foundation (free) AND 3 – American Gastroenterological Association Institute guideline on the management of Crohn’s disease after surgical resection – National Guideline Clearinghouse (free) AND 4 – Management of adult pancreatic injuries: a practice management guideline from the Eastern Association for the Surgery of Trauma – National Guideline Clearinghouse (free)
10 – Cancer Pain – Updated PDQ Cancer Information Summary, National Cancer Institute (US) (free)
Countries like German and Italy are adopting mandatory vaccination policies
29 May, 2017 | 15:20h | UTCCountries like German and Italy are adopting mandatory vaccination policies
Germany vaccination: Fines plan as measles cases rise – BBC Health News (free) AND German kindergartens must report parents for refusing vaccine advice under new law – Reuters Health News (free)
See also: Italy makes 12 vaccinations compulsory for children and related commentaries in our May 22nd issue, see #2.
Thrombocytosis and cancer
29 May, 2017 | 15:18h | UTCClinical relevance of thrombocytosis in primary care: a prospective cohort study of cancer incidence using English electronic medical records and cancer registry data – British Journal of General Practice (link to abstract – $ for full-text)
Commentaries: Cautions and caveats help buoy Guardian story on using high platelet count for cancer detection – HealthNewsReview (free) High blood platelet count ‘as good a cancer predictor as a lump in the breast’ – The Guardian (free)
Thrombocytosis seems to be a risk marker of cancer in adults, but questions remain about the clinical usefulness of these findings.
Antibiotic therapy for nearly one in four adults with pneumonia does not work
29 May, 2017 | 15:20h | UTC#ATS2017 – Antibiotic therapy for nearly one in four adults with pneumonia does not work – American Thoracic Society, via Science Daily (free) (RT @IDSAInfo see Tweet)
See also: Pneumonia Treatment Failure Rates High – Medscape (free registration required) AND Adults With Pneumonia Often Fail First Antibiotic – MedPage Today (free registration required)
Thrombolysis may reduce complications of deep vein thrombosis
26 May, 2017 | 15:09h | UTCThrombolysis may reduce complications of deep vein thrombosis – NIHR Signal (free)
Original article: Thrombolysis for acute deep vein thrombosis – Cochrane Library (Link to abstract – $ for full-text)
Thrombolysis reduced post-thrombotic syndrome, but lead to more bleeding complications than standard anticoagulation. “Individuals with clots in the pelvis and thigh, which carry higher risk of complications, may be likely to gain most benefit”.
Guidelines on the Management of Intra-Abdominal Infection
26 May, 2017 | 15:10h | UTCRelated: Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free)
Recent articles on payment models published in JAMA
26 May, 2017 | 15:05h | UTCRecent articles on payment models published in JAMA
The Next Generation of Episode-Based Payments – JAMA (free) AND Value-Based Payment Models for Community Health Centers: Time to (Cautiously) Take the Plunge? – JAMA (free) AND Business Model–Related Conflict of Interests in Medicine: Problems and Potential Solutions – JAMA (free)
Reducing Risk After Cancer: Healthy Lifestyle (and Tree Nuts)
26 May, 2017 | 15:06h | UTCAmerican Society of Clinical Oncology (ASCO) 2017 Annual Meeting
Can cashews keep colon cancer patients alive? Study says yes — but cautions abound – STAT News (free) AND Reducing Risk After Cancer: Healthy Lifestyle (and Tree Nuts) – Medscape (free registration required)
Induction of labour within 24 hours, if waters break at 37 weeks of pregnancy, can reduce womb infection
26 May, 2017 | 15:08h | UTCInduction of labour within 24 hours, if waters break at 37 weeks of pregnancy, can reduce womb infection – NIHR Signal (free)
Original article: Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more) – Cochrane Library (Link to abstract – $ for full-text)
“Inducing labour within 24hrs may halve risk of infection in the womb when waters break from 37 weeks” (RT @NIHR_DC see Tweet)
Idiopathic pulmonary fibrosis in adults: diagnosis and management
26 May, 2017 | 15:04h | UTCIdiopathic pulmonary fibrosis in adults: diagnosis and management – NICE Guideline (free)
Diagnostic accuracy of post-mortem CT
26 May, 2017 | 15:07h | UTCEditorial: Targeted coronary post-mortem CT angiography, straight to the heart (free)
Commentary: Digital autopsies should be standard for probable natural deaths, says study – The Guardian (free)
Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease
25 May, 2017 | 14:55h | UTCRecommended: New QRISK-3 2017 Calculator (free)
QRISK-3 risk prediction model was developed with data from 7.89 million patients in the derivation cohort and 2.67 million patients in the validation cohort. QRISK-3 includes more factors than QRISK2 to help enable doctors to identify those at most risk of heart disease and stroke. New risk factors include: 1) Chronic kidney disease, which now includes stage 3 CKD; 2) Migraine; 3) Use of corticosteroids; 4) Systemic lupus erythematosus (SLE); 5) Use of atypical antipsychotics; 6) Severe mental illness; 7) Erectile dysfunction; 8) and Systolic blood pressure variability.
Eating disorders: recognition and treatment
26 May, 2017 | 15:03h | UTCEating disorders: recognition and treatment – NICE Guideline (free)
Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis
25 May, 2017 | 14:53h | UTCEffect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)
Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)
Fri, May 26 – 10 Medical Stories of The Day!
26 May, 2017 | 00:01h | UTC
1 – Cardiovascular Toxicity of Illicit Anabolic-Androgenic Steroid Use – Circulation (link to abstract – $ for full-text)
Commentaries: Anabolic Steroid Use Linked With Myocardial Dysfunction and Accelerated Atherosclerosis – TCTMD (free) AND Chronic anabolic steroid use may damage heart – American Heart Association News (free)
“The findings are a public health concern, given that as many as 1% of young men, not all of them athletes, may use these agents” (from TCTMD above).
Related: Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free)
3 – Thrombolysis may reduce complications of deep vein thrombosis – NIHR Signal (free)
Original article: Thrombolysis for acute deep vein thrombosis – Cochrane Library (Link to abstract – $ for full-text)
Thrombolysis reduced post-thrombotic syndrome, but lead to more bleeding complications than standard anticoagulation. “Individuals with clots in the pelvis and thigh, which carry higher risk of complications, may be likely to gain most benefit”.
4 – Induction of labour within 24 hours, if waters break at 37 weeks of pregnancy, can reduce womb infection – NIHR Signal (free)
Original article: Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more) – Cochrane Library (Link to abstract – $ for full-text)
“Inducing labour within 24hrs may halve risk of infection in the womb when waters break from 37 weeks” (RT @NIHR_DC see Tweet)
Editorial: Targeted coronary post-mortem CT angiography, straight to the heart (free)
Commentary: Digital autopsies should be standard for probable natural deaths, says study – The Guardian (free)
6 – American Society of Clinical Oncology (ASCO) 2017 Annual Meeting
Can cashews keep colon cancer patients alive? Study says yes — but cautions abound – STAT News (free) AND Reducing Risk After Cancer: Healthy Lifestyle (and Tree Nuts) – Medscape (free registration required)
7 – Recent articles on payment models published in JAMA
The Next Generation of Episode-Based Payments – JAMA (free) AND Value-Based Payment Models for Community Health Centers: Time to (Cautiously) Take the Plunge? – JAMA (free) AND Business Model–Related Conflict of Interests in Medicine: Problems and Potential Solutions – JAMA (free)
8 – Idiopathic pulmonary fibrosis in adults: diagnosis and management – NICE Guideline (free)
9 – Eating disorders: recognition and treatment – NICE Guideline (free)
10 – The lap band for weight loss is a tale of medicine gone wrong – VOX (free)
See also a recent study showing high complication rates of laparoscopic gastric band surgeries in our May 23rd issue (see #7)
Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women
25 May, 2017 | 14:52h | UTCOil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study confirms ‘flushing’ blocked fallopian tubes can improve fertility and reduce need for IVF – The Conversation (free) AND Can poppyseed oil help infertile couples conceive? – STAT News (free)
Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation
25 May, 2017 | 14:54h | UTCStroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) – Royal College of Paediatrics and Child Health(free) (RT @bmj_latest see Tweet)
News release: New guidelines launched to help healthcare professionals and parents spot the signs of stroke in children (free)
Other resources: Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) (free)
The lap band for weight loss is a tale of medicine gone wrong
25 May, 2017 | 15:02h | UTCThe lap band for weight loss is a tale of medicine gone wrong – VOX (free)
See also a recent study showing high complication rates of laparoscopic gastric band surgeries in our May 23rd issue (see #7)
Very strict blood sugar control in critically ill children provides no benefit
25 May, 2017 | 14:50h | UTCVery strict blood sugar control in critically ill children provides no benefit – NIHR Signal (free)
Original article (link to abstract – $ for full-text): Tight Glycemic Control in Critically Ill Children – New England Journal of Medicine (free)
Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery
25 May, 2017 | 14:50h | UTCEffect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)
Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)
Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.
Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease
25 May, 2017 | 14:46h | UTCComplete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)
“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”
Human papillomavirus vaccines: WHO position paper
25 May, 2017 | 14:48h | UTC“WHO update on HPV vaccine. Short summary – it’s very safe, very effective, widespread implementation recommended” (RT @michaelgheadsee Tweet)
Factors Associated with Pediatric Mortality from Motor Vehicle Crashes
25 May, 2017 | 14:47h | UTCCommentaries: 43 Percent Of Children Who Died From Car Crashes Were Improperly Restrained – NPR Health News (free)
Thu, May 25 – 10 Medical Stories of The Day!
25 May, 2017 | 00:01h | UTC
Recommended: New QRISK-3 2017 Calculator (free)
QRISK-3 risk prediction model was developed with data from 7.89 million patients in the derivation cohort and 2.67 million patients in the validation cohort. QRISK-3 includes more factors than QRISK2 to help enable doctors to identify those at most risk of heart disease and stroke. New risk factors include: 1) Chronic kidney disease, which now includes stage 3 CKD; 2) Migraine; 3) Use of corticosteroids; 4) Systemic lupus erythematosus (SLE); 5) Use of atypical antipsychotics; 6) Severe mental illness; 7) Erectile dysfunction; 8) and Systolic blood pressure variability.
2 – Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) – Royal College of Paediatrics and Child Health (free PDF) (RT @bmj_latest see Tweet)
News release: New guidelines launched to help healthcare professionals and parents spot the signs of stroke in children (free)
Other resources: Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) (free)
3 – Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)
Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)
4 – Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study confirms ‘flushing’ blocked fallopian tubes can improve fertility and reduce need for IVF – The Conversation (free) AND Can poppyseed oil help infertile couples conceive? – STAT News (free)
5 – Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)
Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)
Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.
6 – Very strict blood sugar control in critically ill children provides no benefit – NIHR Signal (free)
Original article (link to abstract – $ for full-text): Tight Glycemic Control in Critically Ill Children – New England Journal of Medicine (free)
“WHO update on HPV vaccine. Short summary – it’s very safe, very effective, widespread implementation recommended” (RT @michaelghead see Tweet)
Commentaries: 43 Percent Of Children Who Died From Car Crashes Were Improperly Restrained – NPR Health News (free)
9 – Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)
“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”
10 – Angioedema in the emergency department: a practical guide to differential diagnosis and management – International Journal of Emergency Medicine (free) (RT @Gas_Craic see Tweet)
Multiple Myeloma Guidelines
24 May, 2017 | 14:41h | UTCRelated: Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology (free)