Archives
Review: DRESS: What does the emergency physician need to know?
29 Aug, 2017 | 14:54h | UTCDRESS: What does the emergency physician need to know? – emDocs (free)
What We Are Watching—Top Global Infectious Disease Threats
29 Aug, 2017 | 14:53h | UTCWhat We Are Watching—Top Global Infectious Disease Threats, 2013-2016: An Update from CDC’s Global Disease Detection Operations Center – Health Security (free) (RT @greg_folkers see Tweet)
Tue, August 29 – 10 Stories of The Day!
29 Aug, 2017 | 00:18h | UTC
#ESCCongress – Highlights from the European Society of Cardiology Congress 2017 – Part II
1 – #ESCCongress – Oxygen Therapy in Suspected Acute Myocardial Infarction – New England Journal of Medicine (free)
Editorial: Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer (free)
Commentaries: Oxygen therapy does not improve survival in patients with heart attack symptoms (DETO2X-AMI) – ESC Press Releases (free) AND Supplemental Oxygen Provides No Benefit to Patients With Suspected MI: DETO2X-AMI – TCTMD (free) AND Suspected MI and Normal Oxygen Saturation? Don’t Bother with Supplemental Oxygen – Physician’s First Watch (free)
2 – #ESCCongress – Population screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Screening for vascular disease saves one life for every 169 patients assessed (VIVA) – ESC Press Releases (free) AND VIVA: Could Population-Wide Screening Trial for AAA, PAD, and Hypertension Save Lives at Low Cost? – TCTMD (free) AND VIVA: Overall Mortality Significantly Reduced Among Older Men Receiving Triple Vascular Screening – American College of Cardiology, Latest in Cardiology (free)
3 – #ESCCongress – PATHWAY-2 uncovers main cause of drug-resistant hypertension, finds old drugs work best – ESC Press Releases (free) (the results have not been published yet)
Commentary: Prevention And Treatment of Hypertension With Algorithm based therapY-2 – PATHWAY-2 – American College of Cardiology, Latest in Cardiology (free)
4 – #ESCCongress – Bag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest (CAAM) – ESC Press Releases (free) (the results have not been published yet)
Commentary: CAAM: Is Bag-Mask Ventilation Superior to ETI During CPR? – American College of Cardiology, Latest in Cardiology (free)
5 – #ESCCongress – Closure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)
Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)
6 – #ESCCongress – Risk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance (RACE 3) – ESC Press Releases (free) (the results have not been published yet)
Commentaries: Broad, Early AF Risk-Factor Intervention Preserves Sinus Rhythm: RACE-3 – Medscape (free registration required) AND Routine vs. Aggressive upstream rhythm Control for prevention of Early persistent atrial fibrillation in heart failure study – RACE 3 – American College of Cardiology, Latest in Cardiology (free)
7 – #ESCCongress – The Prognostic Value of Coronary Artery Calcium in the PROMISE Study – Circulation (free PDF)
Editorial: Computed Tomography or Functional Stress Testing for the Prediction of Risk: Can I Have My Cake and Eat It? (free PDF)
Commentary: Prospective Multicenter Imaging Study for Evaluation of Chest Pain – PROMISE – American College of Cardiology, Latest in Cardiology (free)
8 – Why developing countries must improve primary care – The Economist (free) (RT @AnjaNitzscheB see Tweet)
“The changing burden of disease requires a better approach to keeping people healthy”
9 – Necrotizing pancreatitis: Diagnose, treat, consult – Cleveland Clinic Journal of Medicine (free)
Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
10 – Using mesh does not improve results in vaginal prolapse surgery – NIHR Signal (free)
Original article: Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT) – The Lancet (free) AND Commentary: Mesh, graft, or standard repair for prolapse surgery? – The Lancet (free)
“About 12% of vaginal prolapse patients had complications from surgery using mesh” (RT @NIHR_DC see Tweet)
Meta-analysis: Effectiveness of Light Therapy in Cognitively Impaired Persons
29 Aug, 2017 | 14:52h | UTCEffectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials – Journal of The American Geriatric Society (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
#ESCCongress – 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
27 Aug, 2017 | 20:11h | UTC2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) (free) (RT @rafavidalperez see Tweet)
Commentary: ESC Updates Guidelines for Treating STEMI Patients – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
#ESCCongress – 2017 ESC/EACTS Guidelines for the management of valvular heart disease
27 Aug, 2017 | 20:12h | UTC2017 ESC/EACTS Guidelines for the management of valvular heart disease (free) (RT @rafavidalperez see Tweet)
Commentary: European Societies Issue New Valvular Heart Disease Guidelines, With Important Shifts – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
Mon, August 28 – 10 Stories of The Day!
28 Aug, 2017 | 00:14h | UTC
#ESCCongress – Highlights from the European Society of Cardiology Congress 2017
1 – 2017 ESC/EACTS Guidelines for the management of valvular heart disease (free) (RT @rafavidalperez see Tweet)
Commentary: European Societies Issue New Valvular Heart Disease Guidelines, With Important Shifts – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
2 – 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) (free) (RT @rafavidalperez see Tweet)
Commentary: ESC Updates Guidelines for Treating STEMI Patients – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
3 – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries (free) (RT @rafavidalperez see Tweet)
See also: #ESCCongress Slides (free PPT file)
4 – 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS (free) (RT @rafavidalperez see Tweet)
See also: #ESCCongress Slides (free PPT file)
Editorial by Dr. Eugene Braunwald: An Important Step for Thrombocardiology (free)
Commentaries: Cardiovascular Outcomes for People Using Anticoagulation Strategies – COMPASS – American College of Cardiology, Latest in Cardiology (free) AND COMPASS: Does Rivaroxaban Plus Aspirin Improve CV Outcomes in Patients With Stable Atherosclerotic Vascular Disease or PAD? – ACC News Story (free) AND Rivaroxaban, Aspirin, or Both in Stable Coronary Disease – Physician’s First Watch (free)
The primary outcome (composite of cardiovascular death, stroke, or myocardial infarction) occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group (4.1% vs. 5.4% / Absolute risk difference = 1.3% / NNT = 76), but major bleeding events occurred in more patients in the rivaroxaban-plus-aspirin group (3.1% vs. 1.9% / Absolute risk difference = 1.2 / NNH = 83).
Commentaries: Randomized Evaluation of Dual Antithrombotic Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention – RE-DUAL PCI – American College of Cardiology, Latest in Cardiology (free) Dual Antithrombotic Therapy Is Safe for Patients with AF and a New Stent – Physician’s First Watch (free) AND When two is better than three: Dual antithrombotic therapy cuts bleeding risk – Brigham and Women’s Hospital, via ScienceDaily (free)
“In summary, several lines of evidence now suggest that it is safe to treat atrial fibrillation patients who undergo coronary revascularization with anticoagulation (warfarin studied in WOEST, rivaroxaban studied in PIONEER AF-PCI, dabigatran studied in RE-DUAL PCI) and clopidogrel monotherapy” (from American College of Cardiology, Latest in Cardiology).
Editorial: Targeting Inflammation in Coronary Artery Disease (free)
Commentaries: Anti-Inflammatory Therapy for Atherosclerotic Disease: A Step Closer? – Physician’s First Watch (free) AND CANTOS: Anti-inflammatory Agent Canakinumab Modestly Reduces Major CVD Events – TCTMD (free) AND CANTOS Validates Role Of Inflammation In Heart Disease – Cardiobrief (free)
“This widely anticipated study delivered some modestly positive results (fewer nonfatal MIs), some worrisome results (increased fatal infections), and some unexpected results (fewer cancer deaths)” (from Physician’s First Watch).
Commentary: CASTLE-AF: Catheter Ablation vs. Conventional Therapy For Patients With AFib and LV Dysfunction – American College of Cardiology, Latest in Cardiology (free)
The study has not been published yet, but the results suggest that patients with symptomatic paroxysmal or persistent AF and heart failure with ejection fraction less than 35% may have a better outcome with catheter ablation.
Commentaries: What Do Implanted Cardiac Monitors Reveal About Atrial Fibrillation? – JAMA Cardiology (free) AND REVEAL AF: Incidence of AFib Could Be Substantial in Older Patients With Stroke Risk Factors – American College of Cardiology, Latest in Cardiology (free) AND Detection of Undiagnosed AF Using Insertable Cardiac Monitors – American College of Cardiology, Latest in Cardiology (free)
Implanted Cardiac Monitors showed the incidence of intermittent atrial fibrillation is extremely common among older individuals with stroke risk factors, but the clinical significance of these findings (do they need to be anticoagulated??) remains to be determined by further trials.
“Previous long-term monitoring studies have suggested that patients with short episodes of subclinical AF have a lower risk of stroke compared with traditional clinical AF, which raises important questions about the risk-benefit ratio of anticoagulation in this setting” (from Latest in Cardiology).
10 – CI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Patients With Type 1 Diabetes and Multivessel Disease Have Greater Benefit From CABG Than PCI – American College of Cardiology, Latest in Cardiology (free) AND Revascularization in Patients With Type 1 Diabetes – American College of Cardiology, Latest in Cardiology (free) AND CABG Appears Superior to PCI for Patients With Type 1 Diabetes, Multivessel Disease – TCTMD (free)
“The observational findings support existing recommendations favoring surgical revascularization in patients with diabetes” (from TCTMD).
#ESCCongress – Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation
27 Aug, 2017 | 20:07h | UTCCommentaries: Randomized Evaluation of Dual Antithrombotic Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention – RE-DUAL PCI – American College of Cardiology, Latest in Cardiology (free) Dual Antithrombotic Therapy Is Safe for Patients with AF and a New Stent – Physician’s First Watch (free) AND When two is better than three: Dual antithrombotic therapy cuts bleeding risk – Brigham and Women’s Hospital, via ScienceDaily (free)
“In summary, several lines of evidence now suggest that it is safe to treat atrial fibrillation patients who undergo coronary revascularization with anticoagulation (warfarin studied in WOEST, rivaroxaban studied in PIONEER AF-PCI, dabigatran studied in RE-DUAL PCI) and clopidogrel monotherapy” (from American College of Cardiology, Latest in Cardiology).
#ESCCongress – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases
27 Aug, 2017 | 20:10h | UTC2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries (free) (RT @rafavidalperez see Tweet)
See also: #ESCCongress Slides (free PPT file)
#ESCCongress – Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
27 Aug, 2017 | 20:06h | UTCEditorial: Targeting Inflammation in Coronary Artery Disease (free)
Commentaries: Anti-Inflammatory Therapy for Atherosclerotic Disease: A Step Closer? – Physician’s First Watch (free) AND CANTOS: Anti-inflammatory Agent Canakinumab Modestly Reduces Major CVD Events – TCTMD (free) AND CANTOS Validates Role Of Inflammation In Heart Disease – Cardiobrief (free)
“This widely anticipated study delivered some modestly positive results (fewer nonfatal MIs), some worrisome results (increased fatal infections), and some unexpected results (fewer cancer deaths)” (from Physician’s First Watch).
#ESCCongress – 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease
27 Aug, 2017 | 20:09h | UTC2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS (free) (RT @rafavidalperez see Tweet)
See also: #ESCCongress Slides (free PPT file)
#ESCCongress – Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
27 Aug, 2017 | 20:08h | UTCEditorial by Dr. Eugene Braunwald: An Important Step for Thrombocardiology (free)
Commentaries: Cardiovascular Outcomes for People Using Anticoagulation Strategies – COMPASS – American College of Cardiology, Latest in Cardiology (free) AND COMPASS: Does Rivaroxaban Plus Aspirin Improve CV Outcomes in Patients With Stable Atherosclerotic Vascular Disease or PAD? – ACC News Story (free) AND Rivaroxaban, Aspirin, or Both in Stable Coronary Disease – Physician’s First Watch (free)
The primary outcome (composite of cardiovascular death, stroke, or myocardial infarction) occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group (4.1% vs. 5.4% / Absolute risk difference = 1.3% / NNT = 76), but major bleeding events occurred in more patients in the rivaroxaban-plus-aspirin group (3.1% vs. 1.9% / Absolute risk difference = 1.2 / NNH = 83).
Review: Malignant Otitis Externa: Diagnosis and Treatment
26 Aug, 2017 | 20:30h | UTCMalignant Otitis Externa: Diagnosis and Treatment – emDocs (free)
#ESCCongress – Incidence of Previously Undiagnosed Atrial Fibrillation Using Insertable Cardiac Monitors in a High-Risk Population
27 Aug, 2017 | 20:03h | UTCCommentaries: What Do Implanted Cardiac Monitors Reveal About Atrial Fibrillation? – JAMA Cardiology (free) AND REVEAL AF: Incidence of AFib Could Be Substantial in Older Patients With Stroke Risk Factors – American College of Cardiology, Latest in Cardiology (free) AND Detection of Undiagnosed AF Using Insertable Cardiac Monitors – American College of Cardiology, Latest in Cardiology (free)
Implanted Cardiac Monitors showed the incidence of intermittent atrial fibrillation is extremely common among older individuals with stroke risk factors, but the clinical significance of these findings (do they need to be anticoagulated??) remains to be determined by further trials.
“Previous long-term monitoring studies have suggested that patients with short episodes of subclinical AF have a lower risk of stroke compared with traditional clinical AF, which raises important questions about the risk-benefit ratio of anticoagulation in this setting” (from Latest in Cardiology).
#ESCCongress – Catheter ablation improves outcomes in patients with heart failure and atrial fibrillation
27 Aug, 2017 | 20:03h | UTCCommentary: CASTLE-AF: Catheter Ablation vs. Conventional Therapy For Patients With AFib and LV Dysfunction – American College of Cardiology, Latest in Cardiology (free)
The study has not been published yet, but the results suggest that patients with symptomatic paroxysmal or persistent AF and heart failure with ejection fraction less than 35% may have a better outcome with catheter ablation.
Study: Is Parkinson’s Care Via Telemedicine as Effective as Going to the Clinic?
26 Aug, 2017 | 20:24h | UTCNational randomized controlled trial of virtual house calls for Parkinson disease – Neurology (link to abstract – $ for full-text)
Press release: Is Parkinson’s Care Via Telemedicine as Effective as Going to the Clinic? – American Academy of Neurology (free)
Commentaries: How Telemedicine Helps Those With Parkinson’s – Huffington Post (free) AND Telemedicine Equals Office Visits in Parkinson’s – MedPage Today (free registration required)
China’s embrace of embryo selection raises thorny questions
26 Aug, 2017 | 20:08h | UTCChina’s embrace of embryo selection raises thorny questions – Nature News (free)
“Fertility centres are making a massive push to increase preimplantation genetic diagnosis in a bid to eradicate certain diseases”.
#ESCCongress – CI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease
27 Aug, 2017 | 20:02h | UTCCI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Patients With Type 1 Diabetes and Multivessel Disease Have Greater Benefit From CABG Than PCI – American College of Cardiology, Latest in Cardiology (free) AND Revascularization in Patients With Type 1 Diabetes – American College of Cardiology, Latest in Cardiology (free)
CABG Appears Superior to PCI for Patients With Type 1 Diabetes, Multivessel Disease – TCTMD (free)
“The observational findings support existing recommendations favoring surgical revascularization in patients with diabetes” (from TCTMD).
Using mesh does not improve results in vaginal prolapse surgery
26 Aug, 2017 | 19:58h | UTCUsing mesh does not improve results in vaginal prolapse surgery – NIHR Signal (free)
Original article: Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT) – The Lancet (free) AND Commentary: Mesh, graft, or standard repair for prolapse surgery? – The Lancet (free)
“About 12% of vaginal prolapse patients had complications from surgery using mesh” (RT @NIHR_DC see Tweet)
Review: Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally
26 Aug, 2017 | 20:03h | UTCRelated: A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention – STAT (free) CDC keeping a watchful eye on Candida auris – CIDRAP (free) AND CDC reports uptick in Candida auris cases – CIDRAP (free)
Viewpoint: Management of Parkinson Disease in 2017
26 Aug, 2017 | 20:17h | UTCViewpoint: Management of Parkinson Disease in 2017: Personalized Approaches for Patient-Specific Needs – JAMA (free)
Study: Is late-life dependency increasing or not?
26 Aug, 2017 | 17:03h | UTCCommentaries: The burden of triumph: meeting health and social care needs – The Lancet (free) AND Do we really need 200,000 more care home beds? – The Guardian (free) AND Time spent frail in old age ‘doubles’ – BBC (free)
“The amount of time spent needing daily care in late life has doubled in England over the past two decades, a study suggests”. (from BBC)
Review: Predicting Volume Responsiveness in the Emergency Department
26 Aug, 2017 | 19:38h | UTCPredicting Volume Responsiveness in the Emergency Department – emDocs (free)
Systematic review: The typically developing paediatric foot: how flat should it be?
26 Aug, 2017 | 19:42h | UTC
Study: Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis
26 Aug, 2017 | 16:22h | UTCSource: ACP Journal Wise ($)
“Epidural injections of corticosteroid plus lidocaine offered no benefits from 6 weeks to 12 months beyond that of injections of lidocaine alone”