Archives
Are expanding disease definitions unnecessarily labelling women with polycystic ovary syndrome?
30 Aug, 2017 | 18:03h | UTCCommentaries: Why the definition of polycystic ovary syndrome harms women – Medical News Today (free) AND Five commonly over-diagnosed conditions and what we can do about them – The Conversation (free)
Proposal Guidelines for Standardized Operating Procedures of Brain Autopsy
30 Aug, 2017 | 17:58h | UTC
Guideline: Pancreatic Adenocarcinoma
30 Aug, 2017 | 18:00h | UTCPancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology – JNCCN (free)
Related: Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update (free) AND Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Summary (free) AND Locally Advanced Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Summary (free)
Guidelines: Thyroid Nodule Molecular Fine-Needle Aspiration Cytology Diagnostics
30 Aug, 2017 | 17:59h | UTC
#ESCCongress – Study: Oxygen Therapy in Suspected Acute Myocardial Infarction
29 Aug, 2017 | 15:15h | UTCOxygen Therapy in Suspected Acute Myocardial Infarction – New England Journal of Medicine (free)
Editorial: Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer (free)
Commentaries: Oxygen therapy does not improve survival in patients with heart attack symptoms (DETO2X-AMI) – ESC Press Releases (free) AND Supplemental Oxygen Provides No Benefit to Patients With Suspected MI: DETO2X-AMI – TCTMD (free) AND Suspected MI and Normal Oxygen Saturation? Don’t Bother with Supplemental Oxygen – Physician’s First Watch (free)
Wed, August 30 – 10 Stories of The Day!
30 Aug, 2017 | 00:02h | UTC
#ESCCongress – Highlights from the European Society of Cardiology Congress 2017 – Part III
1 – #ESCCongress – Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Revisiting dietary fat guidelines? (PURE) – ESC Press Release (free) AND PURE Investigators: Rethink Diet Guidance to Plug More Fats, Fewer Carbs – TCTMD (free) AND International study shows moderate consumption of fats and carbohydrates best for health – McMaster University, via EurekAlert (free) AND PURE: Findings Could Have Implications For Global Dietary Guidelines – ACC News Story (free) AND Huge Diet Study Questions Conventional Wisdom About Carbs And Fats – Cardiobrief (free)
2 – #ESCCongress – Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Reassessing the benefits of plant-based eating (PURE) – ESC Press Release (free) Fruit, Vegetable, Legume Intake and CVD Events – American College of Cardiology, Latest in Cardiology (free) AND Life-saving fruit and vegetable diet need only be three portions – study – The Guardian (free) AND Less Is More? Health Benefits of Fruits, Vegetables, and Legumes Seen at Lower Intake Levels – TCTMD (free)
3 – #ESCCongress – Study confirms safety of rapid algorithm to rule-out and rule-in myocardial infarction – ESC Press Release (free) (the results have not been published yet)
Commentary: ESC Rapid Rule-In, Rule-Out Algorithm for NSTEMI Safe, Accurate – Medscape (free registration required)
Related guideline: 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (free) AND Other Resources (free)
4 – #ESCCongress – Underweight associated with highest mortality and costs after cardiac catheterization (free) (the results have not been published yet)
Commentaries: Underweight and Overlooked: Low BMI Patients May Be Highest-Risk Post-PCI – TCTMD (free) AND Underweight Patients Fare Worse After Heart Catheterization – Medscape (free registration required) AND ESC 2017: Underweight Is Associated With Highest Mortality and Costs After Cardiac Catheterization – PracticeUpdate (free registration required)
5 – #ESCCongress – Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease – New England Journal of Medicine (free)
Commentaries: Anacetrapib REVEALs ‘Modest’ Effect on Cardiovascular Outcomes – Medscape (free registration required) AND Anacetrapib Finds (Modest) Success Where All Other CETP Inhibitors Failed – TCTMD (free) AND REVEAL Revealed: A Slightly Positive CETP Inhibitor Trial – Cardiobrief (free)
Interesting new drug, but with modest benefits. During the median follow-up period of 4.1 years, the primary outcome occurred in fewer patients in the anacetrapib group than in the placebo group (10.8% vs. 11.8% / absolute risk difference = 1%, meaning 100 patients would have to be treated for 4.1 years to benefit 1 patient)
6 – #ESCCongress – Automatic external defibrillators save lives in amateur sports and fitness centres (free) (the results have not been published yet)
“Neurologically intact survival was 93% for patients treated with an onsite Automatic external defibrillator (AED) compared to 9% without an AED”
7 – Richard Lehman’s journal review, 29 August 2017 – The BMJ Blogs (free)
Richard Lehman reviews the latest research in the top medical journals.
Commentary: International Consensus (or Not) on Management of Advanced Prostate Cancer – ASCO Post (free)
10 – Clinical Report: Pediatric Integrative Medicine – American Academy of Pediatrics (free)
AAP News: From acupuncture to yoga, report updates integrative medicine therapies (free)
Commentaries: AAP Recommendations Address Complementary Therapies – Medscape (free registration required) AND AAP: Counsel on Complementary Medicine: Natural doesn’t always mean safe – MedPage Today (free registration required)
#ESCCongress – Study: Screening for vascular disease saves one life for every 169 patients assessed
29 Aug, 2017 | 15:14h | UTCPopulation screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Screening for vascular disease saves one life for every 169 patients assessed (VIVA) – ESC Press Releases (free) AND VIVA: Could Population-Wide Screening Trial for AAA, PAD, and Hypertension Save Lives at Low Cost? – TCTMD (free) AND VIVA: Overall Mortality Significantly Reduced Among Older Men Receiving Triple Vascular Screening – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: drug-resistant hypertension – old drugs work best
29 Aug, 2017 | 15:13h | UTCPATHWAY-2 uncovers main cause of drug-resistant hypertension, finds old drugs work best – ESC Press Releases (free) (the results have not been published yet)
Commentary: Prevention And Treatment of Hypertension With Algorithm based therapY-2 – PATHWAY-2 – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Bag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest
29 Aug, 2017 | 15:11h | UTCBag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest (CAAM) – ESC Press Releases (free) (the results have not been published yet)
Commentary: CAAM: Is Bag-Mask Ventilation Superior to ETI During CPR? – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Risk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance
29 Aug, 2017 | 15:08h | UTCRisk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance (RACE 3) – ESC Press Releases (free) (the results have not been published yet)
Commentaries: Broad, Early AF Risk-Factor Intervention Preserves Sinus Rhythm: RACE-3 – Medscape (free registration required) AND Routine vs. Aggressive upstream rhythm Control for prevention of Early persistent atrial fibrillation in heart failure study – RACE 3 – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: The Prognostic Value of Coronary Artery Calcium
29 Aug, 2017 | 15:07h | UTCThe Prognostic Value of Coronary Artery Calcium in the PROMISE Study – Circulation (free PDF)
Editorial: Computed Tomography or Functional Stress Testing for the Prediction of Risk: Can I Have My Cake and Eat It? (free PDF)
Commentary: Prospective Multicenter Imaging Study for Evaluation of Chest Pain – PROMISE – American College of Cardiology, Latest in Cardiology (free)
#ESCCongress – Study: Closure of left atrial appendage during heart surgery protects the brain
29 Aug, 2017 | 15:09h | UTCClosure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)
Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)
Why developing countries must improve primary care
29 Aug, 2017 | 15:06h | UTCWhy developing countries must improve primary care – The Economist (free) (RT @AnjaNitzscheB see Tweet)
“The changing burden of disease requires a better approach to keeping people healthy”
Guidelines for emergency repair of complicated abdominal wall hernias
29 Aug, 2017 | 15:03h | UTC
Management Guidelines for Metal-on-metal Hip Resurfacing Arthroplasty
29 Aug, 2017 | 15:02h | UTC
Guidelines for the diagnosis of fibromyalgia
29 Aug, 2017 | 15:05h | UTCNew guidelines for the diagnosis of fibromyalgia – Revista Brasileira de Reumatologia (free)
Review: Necrotizing pancreatitis
29 Aug, 2017 | 15:06h | UTCNecrotizing pancreatitis: Diagnose, treat, consult – Cleveland Clinic Journal of Medicine (free)
Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
Systematic Review: Topical Antibiotics for Impetigo
29 Aug, 2017 | 15:01h | UTC
Guideline: diagnosis and treatment of osteoporosis in men
29 Aug, 2017 | 15:04h | UTC
Clinical practice guidelines for congenital hyperinsulinism
29 Aug, 2017 | 15:02h | UTCClinical practice guidelines for congenital hyperinsulinism – Clinical Pediatric Endocrinology (free)
Systematic Review: Deferasirox for managing iron overload in people with thalassaemia
29 Aug, 2017 | 14:56h | UTCDeferasirox for managing iron overload in people with thalassaemia – Cochrane Library (free)
Full review: Deferasirox for managing iron overload in people with thalassaemia – Cochrane Library (link to abstract – $ for full-text)
Iron chelation with oral Deferasirox (instead of injected deferoxamine) may offer an important treatment option for people with thalassaemia and secondary iron overload.
Systematic Review: Benefits and harms of sugammadex versus neostigmine in reversing induced paralysis
29 Aug, 2017 | 14:59h | UTCFull review: Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults – Cochrane Library (link to abstract – $ for full-text)
“sugammadex may work more rapidly than neostigmine to reverse neuromuscular block in adults” (RT @CochraneUK see Tweet)
Study: Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray
29 Aug, 2017 | 14:54h | UTCCommunity-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray: Pathogens, Severity, and Clinical Outcomes – Chest (link to abstract – $ for full-text)
Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
“Adults hospitalized with CAP who had radiologic evidence of pneumonia on CT but not concurrent CXR had similar pathogens, disease severity, and outcomes compared with patients who had signs of pneumonia on CXR”.
Novel Statistical Methods: Bayesian Analysis
29 Aug, 2017 | 14:55h | UTCNovel Statistical Methods: Bayesian Analysis: A Practical Approach to Interpret Clinical Trials and Create Clinical Practice Guidelines – Circulation (free)
Editor’s Perspective: When Bayes Comes to Town (free)
Guideline: Osteoarthritis of the Knee Clical Care Standard
29 Aug, 2017 | 15:00h | UTCOsteoarthritis of the Knee Clical Care Standard – Australian Commission on Safety and Quality in Health Care (PDF Guideline and other resources)
Source: Research Review Australia (free resource to find articles of interest)