Archives
Guidelines: Diagnosis and management of Raynaud’s phenomenon
27 Sep, 2017 | 14:14h | UTCESVM guidelines: the diagnosis and management of Raynaud’s phenomenon (free PDF)
Guidelines for autopsy investigation of sudden cardiac death
27 Sep, 2017 | 14:16h | UTC
Guidelines for procedural sedation and analgesia in adults
27 Sep, 2017 | 14:17h | UTC
Review: A Test in Context: Lipid Profile, Fasting Versus Nonfasting
27 Sep, 2017 | 14:06h | UTCA Test in Context: Lipid Profile, Fasting Versus Nonfasting – Journal of The American College of Cardiology (link to abstract and free infographic – $ for full-text)
Commentary: Is fasting before a lipid panel necessary? – Cardiovascular Business (free)
Related guideline: Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine (free) AND Commentary: New guidelines simplify cholesterol tests: no fasting needed – STAT (free)
Draft Recommendation Statement: Falls Prevention in Community-Dwelling Older Adults
27 Sep, 2017 | 14:07h | UTCCommentaries: USPSTF Draft Recommendations for Falls and Fracture Prevention – Medscape (free registration required) AND USPSTF Draft Statement: Vitamin D Supplements No Longer Recommended to Prevent Falls in Seniors – Physician’s First Watch (free)
Related guidelines: Falls in older people: assessing risk and prevention – NICE (free) AND Evidence-based guidelines for fall prevention in Korea (free) AND Summary of the Updated American Geriatrics Society/British Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons (free PDF) AND Management of Falls in Community-Dwelling Older Adults: Clinical Guidance Statement From the Academy of Geriatric Physical Therapy of the American Physical Therapy Association (free) AND Prevention of fall-related injuries in the elderly: An Eastern Association for the Surgery of Trauma practice management guideline (free)
Meta-analysis: Efficacy of recommended drugs against soil transmitted helminths
27 Sep, 2017 | 14:04h | UTCCommentary: Reduced Efficacy of Anthelmintic Drugs – MyScience (free)
Effects of a rise in cigarette price on cigarette consumption, tobacco taxation revenues, and of smoking-related deaths
27 Sep, 2017 | 14:05h | UTCSee also: Smoking prevalence and attributable disease burden in 195 countries and territories in our April 7th issue (see #1) AND WHO report on the global tobacco epidemic 2017 in our July 20th issue (see #1) AND “Tobacco Endgame” policies in our May 12th issue (see #3).
Cohort Study: Childhood onset inflammatory bowel disease and risk of cancer
27 Sep, 2017 | 14:03h | UTCEditorial: Increased risk of cancer in children with inflammatory bowel disease (free)
Commentaries: Inflammatory Bowel Disease in Childhood Tied to Higher Cancer Risk Later – Physician’s First Watch (free) AND IBD in Childhood Raises Cancer Risk – Medscape (free registration required)
Pregnant Women Should Still Get The Flu Vaccine, Doctors Advise
27 Sep, 2017 | 13:58h | UTCPregnant Women Should Still Get The Flu Vaccine, Doctors Advise – NPR (free)
Statement: It is Safe to Receive Flu Shot During Pregnancy – American College of Obstetricians and Gynecologists (free)
See original study showing a possible association between flu vaccine and miscarriage in our September 21st issue (see #6)
Clinical Report: Infectious Diseases Associated With Organized Sports and Outbreak Control
27 Sep, 2017 | 14:00h | UTCNews release: AAP Offers New Guidance on Preventing Spread of Infectious Diseases Associated with Organized Sports (free)
Commentary: When Athletes Share Infections – The New York Times (10 articles per month are free)
Randomized Controled Trial: Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control
27 Sep, 2017 | 14:02h | UTCEffect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
Wed, September 27 – 10 Stories of The Day!
27 Sep, 2017 | 00:05h | UTC
1 – Draft Recommendation Statement: Falls Prevention in Community-Dwelling Older Adults: Interventions – U.S. Preventive Services Task Force (free)
Commentaries: USPSTF Draft Recommendations for Falls and Fracture Prevention – Medscape (free registration required) AND USPSTF Draft Statement: Vitamin D Supplements No Longer Recommended to Prevent Falls in Seniors – Physician’s First Watch (free)
Related guidelines: Falls in older people: assessing risk and prevention – NICE (free) AND Evidence-based guidelines for fall prevention in Korea (free) AND Summary of the Updated American Geriatrics Society/British Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons (free PDF) AND Management of Falls in Community-Dwelling Older Adults: Clinical Guidance Statement From the Academy of Geriatric Physical Therapy of the American Physical Therapy Association (free) AND Prevention of fall-related injuries in the elderly: An Eastern Association for the Surgery of Trauma practice management guideline (free)
2 – Review: A Test in Context: Lipid Profile, Fasting Versus Nonfasting – Journal of The American College of Cardiology (link to abstract and free infographic – $ for full-text)
Commentary: Is fasting before a lipid panel necessary? – Cardiovascular Business (free)
Related guideline: Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine (free) AND Commentary: New guidelines simplify cholesterol tests: no fasting needed – STAT (free)
See also: Smoking prevalence and attributable disease burden in 195 countries and territories in our April 7th issue (see #1) AND WHO report on the global tobacco epidemic 2017 in our July 20th issue (see #1) AND “Tobacco Endgame” policies in our May 12th issue (see #3).
Commentary: Reduced Efficacy of Anthelmintic Drugs – MyScience (free)
Editorial: Increased risk of cancer in children with inflammatory bowel disease (free)
Commentaries: Inflammatory Bowel Disease in Childhood Tied to Higher Cancer Risk Later – Physician’s First Watch (free) AND IBD in Childhood Raises Cancer Risk – Medscape (free registration required)
6 – Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
7 – Clinical Report: Infectious Diseases Associated With Organized Sports and Outbreak Control – American Academy of Pediatrics (free)
News release: AAP Offers New Guidance on Preventing Spread of Infectious Diseases Associated with Organized Sports (free)
Commentary: When Athletes Share Infections – The New York Times (10 articles per month are free)
Commentaries: Precision public health: mapping child mortality in Africa – The Lancet (free) AND ‘Precision public health:’ 5 x 5 kilometer mapping identifies significant differences in child deaths throughout Africa – Institute for Health Metrics and Evaluation (free)
9 – Pregnant Women Should Still Get The Flu Vaccine, Doctors Advise – NPR (free)
Statement: It is Safe to Receive Flu Shot During Pregnancy – American College of Obstetricians and Gynecologists (free)
See original study showing a possible association between flu vaccine and miscarriage in our September 21st issue (see #6)
10 – Diagnostic Accuracy of Novel and Traditional Rapid Tests for Influenza Infection Compared With Reverse Transcriptase Polymerase Chain Reaction: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Newer influenza diagnostic tests more accurate than traditional tests – Clinical Advisor (free) AND Rapid tests linked to quicker and more accurate results for influenza diagnosis than traditional tests – 2 Minute Medicine (free)
Mapping under-5 and neonatal mortality in Africa
27 Sep, 2017 | 13:59h | UTCCommentaries: Precision public health: mapping child mortality in Africa – The Lancet (free) AND ‘Precision public health:’ 5 x 5 kilometer mapping identifies significant differences in child deaths throughout Africa – Institute for Health Metrics and Evaluation (free)
Meta-analysis: Diagnostic Accuracy of Tests for Influenza
27 Sep, 2017 | 13:58h | UTCDiagnostic Accuracy of Novel and Traditional Rapid Tests for Influenza Infection Compared With Reverse Transcriptase Polymerase Chain Reaction: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Newer influenza diagnostic tests more accurate than traditional tests – Clinical Advisor (free) AND Rapid tests linked to quicker and more accurate results for influenza diagnosis than traditional tests – 2 Minute Medicine (free)
Draft Guideline: Most common ear infections should not be treated with antibiotics
25 Sep, 2017 | 22:28h | UTCNews release: Draft Guideline: Most common ear infections should not be treated with antibiotics, says NICE (free)
Commentaries: Common ear infections don’t need antibiotics, health watchdog says – The Guardian (free) AND Antibiotics not recommended for acute otitis, says NICE (free)
Tue, September 26 – 10 Stories of The Day!
26 Sep, 2017 | 00:32h | UTC
1 – News release: Draft Guideline: Most common ear infections should not be treated with antibiotics, says NICE (free)
Commentaries: Common ear infections don’t need antibiotics, health watchdog says – The Guardian (free) AND Antibiotics not recommended for acute otitis, says NICE (free)
2 – Low-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study – Circulation (link to abstract – $ for full-text)
Commentaries: Stopping Aspirin Hikes CV risk – Cardiobrief (free) AND Aspirin Discontinuation Tied to Increased Risk for CV Events – Physician’s First Watch (free)
Related: The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)
4 – Olfaction and incident Parkinson disease in US white and black older adults – Neurology (link to abstract – $ for full-text)
Commentaries: Parkinson’s: Sniff test could predict risk up to a decade earlier – Medical News Today (free) AND Can a Smell Test Predict Parkinson’s? – MedPage Today (free registration required) AND Scratch-and-sniff test could predict Parkinson’s even earlier – Michigan State University, via EurekAlert (free) AND Parkinson’s Disease May Be Diagnosed With Smell Test 10 Years Before Symptoms – Medical Daily (free)
Commentaries: Four questions to ask when reading or writing about water fluoridation and IQ – HealthNewsReview (free) AND High fluoride levels in pregnancy may lower offspring IQ – Medical News Today (free) AND Fluoride exposure in utero linked to lower IQ in kids, study says – CNN (free)
6 – Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: In Pregnant Women with Type 1 Diabetes, Continuous Glucose Monitoring Linked to Better Outcomes – Physician’s First Watch (free) AND All pregnant women with type 1 diabetes should be offered continuous glucose monitoring – OnMedica (free)
7 – Richard Lehman’s journal review, 25 September 2017 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
8 – The path to longer and healthier lives for all Africans by 2030: the Lancet Commission on the future of health in sub-Saharan Africa – The Lancet (free registration required)
Invited commentaries: Africa and health: a Commission to accelerate success (free registration required) AND Longer and healthier lives for all Africans by 2030: perspectives and action of WHO AFRO (free registration required)
9 – Modeling the Cost-Effectiveness of Interventions to Reduce Suicide Risk Among Hospital Emergency Department Patients – Psychiatric Services (link to abstract – $ for full-text)
Commentary: Life-Saving Post-ER Suicide Prevention Strategies are Cost Effective – National Institute of Mental Health (free)
See also related meta-analysis and studies on strategies to prevent suicide in our August 11th issue (see #6 and #7)
10 – Addiction Potential of Cigarettes With Reduced Nicotine Content in Populations With Psychiatric Disorders and Other Vulnerabilities to Tobacco Addiction – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Lowering Nicotine in Cigarettes Could Help Most Vulnerable – MedPage Today (free registration required) AND Could Nicotine Reduction Help Curb Addiction? – Science Newsline (free)
Olfaction and incident Parkinson disease
25 Sep, 2017 | 22:25h | UTCOlfaction and incident Parkinson disease in US white and black older adults – Neurology (link to abstract – $ for full-text)
Commentaries: Parkinson’s: Sniff test could predict risk up to a decade earlier – Medical News Today (free) AND Can a Smell Test Predict Parkinson’s? – MedPage Today (free registration required) AND Scratch-and-sniff test could predict Parkinson’s even earlier – Michigan State University, via EurekAlert (free) AND Parkinson’s Disease May Be Diagnosed With Smell Test 10 Years Before Symptoms – Medical Daily (free)
Cohort Study: Low-Dose Aspirin Discontinuation and Risk of Cardiovascular Events
25 Sep, 2017 | 22:27h | UTCLow-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study – Circulation (link to abstract – $ for full-text)
Commentaries: Stopping Aspirin Hikes CV risk – Cardiobrief (free) AND Aspirin Discontinuation Tied to Increased Risk for CV Events – Physician’s First Watch (free)
This map shows how many years could be added to you life – if the air you breathe was less polluted
25 Sep, 2017 | 22:26h | UTCRelated: The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)
Report: The path to longer and healthier lives for all Africans by 2030
25 Sep, 2017 | 22:21h | UTCThe path to longer and healthier lives for all Africans by 2030: the Lancet Commission on the future of health in sub-Saharan Africa – The Lancet (free registration required)
Invited commentaries: Africa and health: a Commission to accelerate success (free registration required) AND Longer and healthier lives for all Africans by 2030: perspectives and action of WHO AFRO (free registration required)
Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6–12 Years of Age
25 Sep, 2017 | 22:25h | UTCCommentaries: Four questions to ask when reading or writing about water fluoridation and IQ – HealthNewsReview (free) AND High fluoride levels in pregnancy may lower offspring IQ – Medical News Today (free) AND Fluoride exposure in utero linked to lower IQ in kids, study says – CNN (free)
Randomized Controled Trial: Continuous glucose monitoring in pregnant women with type 1 diabetes
25 Sep, 2017 | 22:23h | UTCContinuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: In Pregnant Women with Type 1 Diabetes, Continuous Glucose Monitoring Linked to Better Outcomes – Physician’s First Watch (free) AND All pregnant women with type 1 diabetes should be offered continuous glucose monitoring – OnMedica (free)
Mon, September 25 – 10 Stories of The Day!
25 Sep, 2017 | 00:06h | UTC
1 – The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study – The Lancet (link to abstract – $ for full-text)
Commentaries: Any type of physical exercise is good for the heart – NHS Choices (free) AND Physical Activity of Any Ilk Cuts CVD, Deaths in Global Study: PURE – TCTMD (free) AND Being active saves lives whether a gym workout, walking to work or washing the floor – McMaster University, via ScienceDaily (free) AND Don’t overthink your exercise: just 2.5 hours per week of any kind could help you live longer – VOX (free) AND A daily half hour’s exercise could prevent 1 in 12 early deaths, study shows – Reuters (free)
2 – The Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis – Psychotherapy and Psychosomatics (link to abstract – $ for full-text)
Commentaries: Antidepressant use associated with higher risk of death – OnMedica (free) AND Antidepressants may raise death risk by a third – Medical News Today (free) AND Antidepressants Tied to a Significantly Increased Risk for Death – Medscape (free registration required) AND Antidepressants Associated with Significantly Elevated Risk of Death, Researchers Find – McMaster University, via NewsWise (free)
3 – Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Study Questions Incremental Benefit of Beta-Blockers After Acute MI – TCTMD (free) AND Beta blockers not needed after heart attack if other medications taken – University of North Carolina at Chapel Hill, via Eurekalert (free) AND Adherence to medications post-MI is below 50%; beta-blockers offer little incremental benefit – Cardiovascular Business (free)
Related study published recently: β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
5 – Homepage: Cardiomyopathy Compendium – Circulation Research
– Cardiomyopathies: An Overview, by Eugene Brawnwald (free)
– Classification, Epidemiology, and Global Burden of Cardiomyopathies (free)
– Dilated Cardiomyopathy: Genetic Determinants and Mechanisms (free)
– Hypertrophic Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy (free)
– Hypertrophic Obstructive Cardiomyopathy: Surgical Myectomy and Septal Ablation (free)
– Arrhythmogenic Cardiomyopathy (free)
– Inflammatory Cardiomyopathic Syndromes (free)
– Restrictive Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy (free)
– Pediatric Cardiomyopathies (free)
– Modern Imaging Techniques in Cardiomyopathies (free)
Source: Critical Care Reviews Newsletter
Commentaries: Montelukast Tied to Psychiatric Adverse Events in Kids, Adults – Medscape (free registration required) AND Asthma Drug, Montelukast, Tied to Nightmares, Depression – Drugs.com (free)
7 – Effect of Post–Cesarean Delivery Oral Cephalexin and Metronidazole on Surgical Site Infection Among Obese Women: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Post-Cesarean Antibiotics Reduce Risk for Surgical Site Infections in Obese Women – Physician’s First Watch (free) AND Antibiotics After C-Section Cut Infections in Obese Women – MedPage Today (free registration required) AND Antibiotics cut infection risk in obese women after caesarean – OnMedica (free)
8 – Interventions for treating tuberculous pericarditis – Cochrane Library (free)
News release: Treatment for tuberculosis infection of the membrane around the heart (free)
“For HIV-negative patients, corticosteroids may reduce death. For HIV-positive patients not on antiretroviral drugs, corticosteroids may reduce constriction. For HIV-positive patients with good antiretroviral drug viral suppression, clinicians may consider the results from HIV-negative patients more relevant”.
9 – Mechanical Thrombectomy Outcomes With and Without Intravenous Thrombolysis in Stroke Patients: A Meta-Analysis – Stroke (link to abstract – $ for full-text)
Commentary: Better outcomes seen in patients who received IV thrombolysis before thrombectomy – ACP Hospitalist (free)
“The results support current guideline recommendations to give intravenous thrombolysis to eligible patients even if they are being considered for mechanical thrombectomy, according to the meta-analysis authors” (from ACP)
10 – Blood test and ECG may safely rule out heart attack – NIHR Signal (free)
Original article: Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text) and Commentary: High-sensitivity troponin T result may help rule out of myocardial infarction – 2 Minute Medicine (free)
Richard Lehman’s journal review – 25 September 2017
25 Sep, 2017 | 22:22h | UTCRichard Lehman’s journal review, 25 September 2017 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Interventions to Reduce Suicide Risk Among Hospital Emergency Department Patients
25 Sep, 2017 | 22:20h | UTCModeling the Cost-Effectiveness of Interventions to Reduce Suicide Risk Among Hospital Emergency Department Patients – Psychiatric Services (link to abstract – $ for full-text)
Commentary: Life-Saving Post-ER Suicide Prevention Strategies are Cost Effective – National Institute of Mental Health (free)
See also related meta-analysis and studies on strategies to prevent suicide in our August 11th issue (see #6 and #7)


