Archives

Meta-Analysis: Tranexamic Acid Reduces Blood Loss in Intertrochanteric Fractures

16 Feb, 2018 | 00:26h | UTC

Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials – Medicine (free)

Meta-Analysis: High-intensity interval training versus moderate-intensity continuous training within cardiac rehabilitation

16 Feb, 2018 | 00:28h | UTC

High-intensity interval training versus moderate-intensity continuous training within cardiac rehabilitation: a systematic review and meta-analysis – Open Access Journal of Sports Medicine (free)

Meta-analysis: Standard versus extralevator abdominoperineal excision and oncologic outcomes for patients with distal rectal cancer

16 Feb, 2018 | 00:25h | UTC

Standard versus extralevator abdominoperineal excision and oncologic outcomes for patients with distal rectal cancer: A meta-analysis – Medicine (free)

Fri, February 16 – 10 Stories of The Day!

16 Feb, 2018 | 00:01h | UTC

1 – WHO recommendations: intrapartum care for a positive childbirth experience – World Health Organization (free)

News release: Individualized, supportive care key to positive childbirth experience, says WHO (free)

Commentary: Give women more time to give birth, make choices – WHO – Reuters (free)

2 – Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) (free)

Commentary: Fecal transplants move into the mainstream to treat difficult infection – STAT (free)

3 – Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The PRESERVE trial – 2 Minute Medicine (free) AND Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – NEJM Resident 360 (free)

“Among patients at high risk for renal complications who were undergoing angiography, there was no benefit of intravenous sodium bicarbonate over intravenous sodium chloride or of oral acetylcysteine over placebo for the prevention of death, need for dialysis, or persistent decline in kidney function at 90 days or for the prevention of contrast-associated acute kidney injury”.

4 – Review: Physical Activity in the Prevention and Treatment of Coronary Artery Disease – Journal of the American Heart Association (free for a limited period)

5 – Consumption of ultra-processed foods and cancer risk: results from NutriNet-Santé prospective cohort – The BMJ (free)

Editorial: Ultra-processed foods and cancer (free)

Commentaries: ‘Ultra-processed’ foods and cancer: Headlines show the right way, and the wrong way, to frame results from an observational study – HealthNewsReview (free) AND Expert reaction to study looking at highly processed foods and cancer – Science Media Centre (free)

6 – Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Edoxaban for Cancer-Associated Venous Thromboembolism (free)

Commentaries: Edoxaban Noninferior to Dalteparin for Cancer-Associated VTE – Physician’s First Watch (free) AND Oral Edoxaban Noninferior to Dalteparin for Cancer-Related Venous Thromboembolism – Cardiology Advisor (free)

7 – Mortality in single fathers compared with single mothers and partnered parents: a population-based cohort study – The Lancet Public Health (free)

Commentaries: Premature mortality in single fathers – The Lancet Public Health (free) AND Single fathers have highest risk of early death – OnMedica (free) AND Single Fathers Are More Likely to Die Early, Study Says – TIME (free)

8 – Risk of Dementia in Adults With Congenital Heart Disease: Population-Based Cohort Study – Circulation (free PDF)

Commentaries: Congenital heart defects linked to increased risk of dementia – American Heart Association News (free) AND Adult Survivors of Congenital Heart Disease at Increased Risk of Dementia – TCTMD (free)

9 – Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease – Circulation: Genomic and Precision Medicine (free)

Commentary: Genetic Risk Score May Best FH Variant for Predicting Early-Onset CAD – Medscape (free registration required)

“Another study suggests CAD will soon be predicted not by 1 gene (like FH) but groups of genes that can be combined into risk scores” (via @drjohnm see Tweet)

10 – Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes: A Systematic Review and Meta-analysis – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries: Could NOACs Have a Role for Secondary Prevention After STEMI? – TCTMD (free) AND Meta-Analysis: ACS Type Matters for DOAC Use in Secondary Prevention – MedPage Today (free registration required) AND Adding DOACs Beneficial for STEMI — Not Non-STEMI — But with Bleeding Risk – Physician’s First Watch (free)

“63 STEMI patients would need to receive a DOAC to prevent one cardiovascular event, while 96 would need to be treated to cause one major bleeding event”. (from Physician’s First Watch)