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Research: Extrafine Inhaled Triple Therapy Versus Dual Bronchodilator Therapy in COPD

16 Feb, 2018 | 01:05h | UTC

Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

“Steroid-containing fine-mist triple inhaler comp with dry powder double inhaler resulting in 0.09 fewer exacerbations per year. Yup.” (via @RichardLehman1 see Tweet) See Richard Lehman’s point of view

 


Uncertain benefits of BNP blood tests to monitor heart failure treatment

16 Feb, 2018 | 01:08h | UTC

Uncertain benefits of BNP blood tests to monitor heart failure treatment – NIHR Signal (free)

Original article: Effectiveness and cost-effectiveness of serum B-type natriuretic peptide testing and monitoring in patients with heart failure in primary and secondary care: an evidence synthesis, cohort study and cost-effectiveness model – Health Technology Assessment (free)

 


Being overweight or having diabetes are both linked to cancer

16 Feb, 2018 | 01:03h | UTC

Being overweight or having diabetes are both linked to cancer – NIHR Signal (free)

Original article: Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment – The Lancet Diabetes & Endocrinology (free) AND Commentary: Diabetes and adiposity: a heavy load for cancer (free)

 


Evidence Review: Pulmonary Rehabilitation for People with COPD

16 Feb, 2018 | 01:06h | UTC

Pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD): evidence review – Evidently Cochrane (free)

 


Research – Electroconvulsive therapy and age: Age-related clinical features and effectiveness in treatment resistant major depressive episode

16 Feb, 2018 | 01:02h | UTC

Electroconvulsive therapy and age: Age-related clinical features and effectiveness in treatment resistant major depressive episode – Journal of Affective Disorders (link to abstract – $ for full-text)

“Short-term ECT outcome in the treatment of depression in elderly is equivalent to that of young patients in efficacy and tolerability. Old patients reported faster ECT response than younger ones and required less sessions to achieve response and remission” (via @psychopharmacol see Tweet)

 


Perspective: Catheter-Directed Management in Acute Pulmonary Embolism

16 Feb, 2018 | 00:59h | UTC

Catheter-Directed Management in Acute Pulmonary Embolism – American College of Cardiology, Latest in Cardiology (free)

 


Perspective: Your Future Doctor May Not be Human

16 Feb, 2018 | 00:59h | UTC

Perspective: Your Future Doctor May Not be Human. This Is the Rise of AI in Medicine – Futurism (free)

 


Atypical Antipsychotics, Insulin Resistance and Weight; a Meta-Analysis of Healthy Volunteer Studies

16 Feb, 2018 | 01:01h | UTC

Atypical antipsychotics, insulin resistance and weight; a meta-analysis of healthy volunteer studies – Progress in Neuro-Psychopharmacology and Biological Psychiatry (link to abstract – $ for full-text) (via @psychopharmacol see Tweet)

“These findings provide preliminary evidence that atypical antipsychotics cause insulin resistance and weight gain directly, independent of psychiatric disease and may be associated with length of treatment”.

 


Choosing Wisely: American Society for Blood and Marrow Transplantation and the Canadian Blood and Marrow Transplant Group

16 Feb, 2018 | 00:54h | UTC

Choosing Wisely: American Society for Blood and Marrow Transplantation and the Canadian Blood and Marrow Transplant Group – Five Things Physicians and Patients Should Question (free)

News release: ASBMT and CBMTG Release Choosing Wisely BMT Recommendations (free)

 


CEPI, a year in: How can we get ready for the next pandemic?

16 Feb, 2018 | 00:49h | UTC

CEPI, a year in: How can we get ready for the next pandemic? – Devex (free)

Source: International Health Policies Newsletter

 


Research: Intravenous and Topical Tranexamic Acid Alone vs Tourniquet Use for Primary Total Knee Arthroplasty

16 Feb, 2018 | 00:51h | UTC

Intravenous and Topical Tranexamic Acid Alone Are Superior to Tourniquet Use for Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial –  The Journal of Bone and Joint Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


Research: Public Transport Policy, Social Engagement and Mental Health in Older Age

16 Feb, 2018 | 00:50h | UTC

Public transport policy, social engagement and mental health in older age: a quasi-experimental evaluation of free bus passes in England – Journal of Epidemiology and Community Health (free)

Commentary: Free public transport for older adults tied to less depression – Reuters (free)

 


Research: Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults

16 Feb, 2018 | 00:52h | UTC

Prognostic effects of delirium motor subtypes in hospitalized older adults: A prospective cohort study – PLOS One (free) (via @DrMeganHoseyPhD)

“One in three acutely ill hospitalized older adults who suffered hypoactive or mixed delirium died in the hospital”

 


Meta-Analysis: Transcatheter Versus Surgical Aortic Valve Replacement in Patients at Low Surgical Risk

16 Feb, 2018 | 00:48h | UTC

Transcatheter versus surgical aortic valve replacement in patients at low surgical risk: A meta-analysis of randomized trials and propensity score matched observational studies – Catheterization Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: Meta-Analysis Raises ‘Red Flag’ on TAVR in Low-Risk Patients – TCTMD (free)

“Data from six studies show that while short-term mortality is similar between TAVR and SAVR, more low-risk TAVR patients die by 2 years” (from TCTMD)

 


This Startup Makes End-Of-Life Planning A Piece Of Cake

16 Feb, 2018 | 00:41h | UTC

This Startup Makes End-Of-Life Planning A Piece Of Cake – Forbes (free)

 


Consistently High Turnover in the Group of Top Health Care Spenders

16 Feb, 2018 | 00:44h | UTC

Consistently High Turnover in the Group of Top Health Care Spenders – NEJM Catalyst (free)

“Within a given year, most health spending is done by a small group of individuals. However, most of those people are new each year” (via @nejmcatalyst see Tweet)

 


Research: Congenital Zika Virus Brain Damage May Go Undetected in Pregnancy

16 Feb, 2018 | 00:38h | UTC

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain – Nature Medicine (link to abstract – $ for full-text)

Commentary: Zika brain damage may go undetected in pregnancy – Outbreak News Today (free)

 


Review: Permanent pacemaker insertion in patients with conduction abnormalities post transcatheter aortic valve replacement

16 Feb, 2018 | 00:42h | UTC

Permanent pacemaker insertion in patients with conduction abnormalities post transcatheter aortic valve replacement: a review and proposed guidelines – Annals of Translational Medicine (free)

 


Why A Gene Therapy Pioneer Is Raising Concerns About Treatments He Championed

16 Feb, 2018 | 00:40h | UTC

Why A Gene Therapy Pioneer Is Raising Concerns About Treatments He Championed – Forbes (free)

 


Urothelial Carcinoma: The Evolving Landscape of Immunotherapy for Patients with Advanced Disease

16 Feb, 2018 | 00:32h | UTC

Urothelial carcinoma: the evolving landscape of immunotherapy for patients with advanced disease – Research and Reports in Urology (free)

 


Paediatric schistosomiasis: What we know and what we need to know

16 Feb, 2018 | 00:35h | UTC

Paediatric schistosomiasis: What we know and what we need to know – PLOS Neglected Tropical Diseases (free)

 


Obstructive Sleep Apnea: Current Perspectives

16 Feb, 2018 | 00:30h | UTC

Obstructive sleep apnea: current perspectives – Nature and Science of Sleep (free)

 


Review: Congenital Insensitivity to Pain Overview

16 Feb, 2018 | 00:36h | UTC

Congenital Insensitivity to Pain Overview – GeneReviews (free)

 


Review: The Dawn of the Liquid Biopsy in the Fight Against Cancer

16 Feb, 2018 | 00:31h | UTC

The dawn of the liquid biopsy in the fight against cancer – Oncotarget (free)

 


Total Knee Arthroplasty: Improving Outcomes with a Multidisciplinary Approach

16 Feb, 2018 | 00:27h | UTC

Total knee arthroplasty: improving outcomes with a multidisciplinary approach – Journal of Multidisciplinary Healthcare (free)

 


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