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Effect of a Baby-Led Approach to Complementary Feeding on Infant Growth and Overweight

11 Jul, 2017 | 17:42h | UTC

Effect of a Baby-Led Approach to Complementary Feeding on Infant Growth and Overweight: A Randomized Clinical Trial – JAMA Pediatrics (free)

Commentaries: Baby-led weaning doesn’t reduce chances of obesity – OnMedica (free) AND Self-Fed Weaning Babies Less Fussy: But no effect on weight in randomized trial – MedPage Today (free registration required) AND Infant Self-Feeding May Confer Some Benefits but Doesn’t Reduce Obesity Risk – Physician’s First Watch (free)

“Baby-led approaches to introducing solids neither improve nor reduce growth vs traditional spoon-feeding” (RT @JAMAPeds see Tweet)

 


RCT: Palliative Care in Heart Failure

11 Jul, 2017 | 17:07h | UTC

Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial (link to abstract – $ for full-text)

Commentaries: Palliative Care Intervention Improves Quality of Life in Advanced Heart Failure Patients – American College of Cardiology, Latest in Cardiology (free) AND Palliative Care Improves Heart Failure Quality-of-Life – MedPage Today (free registration required)

 


Are There Long-Term Risks to Egg Donors?

11 Jul, 2017 | 16:55h | UTC

Are There Long-Term Risks to Egg Donors? – New York Times (10 articles per month are free)

 


Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Risk Factors

11 Jul, 2017 | 17:12h | UTC

Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Risk Factors: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorial 1: Healthful Physical Activity and Diet Promotion—For the Many or the Few? (free)

Editorial 2: Cardiovascular Risk Factor Control for All (free)

Editorial 3: Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Risk Factors: Is Behavioral Counselling Necessary? (free)

The JAMA Network – For The Media: USPSTF Recommendation Regarding Behavioral Counseling for Cardiovascular Disease Prevention (free)

 


Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

11 Jul, 2017 | 16:54h | UTC

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation – New England Journal of Medicine (free)

Commentary: Adding Midostaurin to Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia With FLT3 Mutation – ASCO Post (free)

 


Shared Decision Making: The Importance of Diagnosing Preferences

11 Jul, 2017 | 16:46h | UTC

Shared Decision Making: The Importance of Diagnosing Preferences – JAMA Internal Medicine (free)

Related: Editorial: Sharing Medicine – A JAMA Internal Medicine Series (free) AND Sharing as the Future of Medicine – JAMA Internal Medicine (free)

 


Concordance of autoimmune disease in a systemic lupus erythematosus twin cohort

11 Jul, 2017 | 16:57h | UTC

Concordance of autoimmune disease in a nationwide danish systemic lupus erythematosus twin cohort – Seminars in Arthritis and Rheumatism (link to abstract – $ for full-text)

Commentary: SLE Concordance in Twins Lower than Previously Reported – MedPage Today (free registration required)

 


Post-Surgical Complications

11 Jul, 2017 | 16:45h | UTC

Post-Surgical Complications – emDocs (free)

Practical review of this common problem in the emergency department.

 


Tue, July 11 – 10 Stories of The Day!

11 Jul, 2017 | 00:04h | UTC

 

1 – Salt intake and Cardiovascular Disease – European Heart Journal (free)

Full report: The technical report on sodium intake and cardiovascular disease in low- and middle-income countries by the joint working group of the World Heart Federation, the European Society of Hypertension and the European Public Health Association (free)

Commentary: CardioBrief: Int’l Experts Call Sodium Guidelines Far Too Restrictive – MedPage Today (free registration required)

Summary of the technical report on sodium intake and cardiovascular disease with key recommendations for individuals and policymakers.

 

2 – Management of Small Renal Masses: American Society of Clinical Oncology Clinical Practice Guideline (free)

Summary: National Guideline Clearinghouse (free)

 

3 – Women with High-Risk Pregnancies Are More Likely To Develop Heart Disease – NPR (free)

Related review: Adverse Pregnancy Conditions, Infertility, and Future Cardiovascular Risk: Implications for Mother and Child – Cardiovascular Drugs and Therapy (free)

 

4 – Just Started! Free Online Course. Science of Exercise – University of Colorado Boulder and Coursera

 

5 – Just Started! Free Online Course. Health for All Through Primary Health Care – Johns Hopkins University and Coursera

 

6 – Effective Care for High-Need Patients: Opportunities for Improving Outcomes, Value, and Health (free PDF)

See also: News release (free) AND Executive summary (free PDF) AND Key Points (free PDF) AND Characteristics of Successful Care Models for High-Need Patients (free PDF)

Commentary: New NAM publication examines improving outcomes, reducing costs for ‘high-needs patients’ – National – National Academies of Sciences, Engineering, and Medicine, via EurekAlert (free)

See more resources on high-need, high-cost patients in our July 4th issue (see #2)

Source: STAT News Newsletter

“Nearly half of the nation’s spending on health care is driven by 5 percent of patients, and improving health outcomes and curbing spending in health care will require identifying who these high-needs patients are and providing coordinated services” (from EurekAlert)

 

7 – Richard Lehman’s journal review / 10 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

8 – Rivastigmine reviewed: doubts about dementia drug – Evidently Cochrane (free)

Related review: Rivastigmine for people with Alzheimer’s disease – Cochrane Library (link to abstract – $ for full-text)

“”Sadly, “small” and “of uncertain clinical importance” are the words chosen by the Cochrane reviewers to describe…” (RT @CochraneUK see Tweet)

 

9 – Cochrane Review: Gabapentin for chronic neuropathic pain in adults – Cochrane Library (link to abstract – $ for full-text)

Commentary: Analgesic Effects of Gabapentin Assessed in Chronic Neuropathic Pain – MPR (free)

“Gabapentin at doses of 1800 mg to 3600 mg daily (1200 mg to 3600 mg gabapentin enacarbil) can provide good levels of pain relief to some people with postherpetic neuralgia and peripheral diabetic neuropathy”.

 

10 – The rise of antibiotic-resistant infections threaten economies – Finantial Times (a few articles per month are free) (RT @greg_folkers see Tweet)

Related report: Drug-Resistant Infections: A Threat to Our Economic Future – World Bank (Free PDF) AND Infographic: Drug Resistant Infections: A Threat to Our Economic Future (free) AND News Release: By 2050, drug-resistant infections could cause global economic damage on par with 2008 financial crisis (free)

 


Deutetrabenazine for treatment of involuntary movements in patients with tardive dyskinesia

11 Jul, 2017 | 16:44h | UTC

Deutetrabenazine for treatment of involuntary movements in patients with tardive dyskinesia (AIM-TD): a double-blind, randomised, placebo-controlled, phase 3 trial – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: Drug Eases Tardive Dyskinesia Linked to Antipsychotic Use – Medscape (free registration required) AND Second Tardive Dyskinesia Drug Works – MedPage Today (free registration required)

 


Association of delay of urgent or emergency surgery with mortality and use of health care resources

10 Jul, 2017 | 15:09h | UTC

Association of delay of urgent or emergency surgery with mortality and use of health care resources: a propensity score–matched observational cohort study – Canadian Medical Association Journal (free)

Commentary: Patients whose emergency surgery is delayed are at higher risk of death – Canadian Medical Association Journal, via EurekAlert (free)

Source: STAT News Newsletter

“Delayed operating room access for emergency surgery was associated with increased risk of inhospital mortality, longer length of stay and higher costs”.

 


The relationship between eosinophilic esophagitis and esophageal cancer

11 Jul, 2017 | 16:44h | UTC

The relationship between eosinophilic esophagitis and esophageal cancer – Diseases of The Esophagus (free)

An analysis of a large database of de-identified electronic medical records (EMRs) with over 40.000.000 patients found no association.

 


Women with High-Risk Pregnancies Are More Likely To Develop Heart Disease

10 Jul, 2017 | 14:59h | UTC

Women with High-Risk Pregnancies Are More Likely To Develop Heart Disease – NPR (free)

Related review: Adverse Pregnancy Conditions, Infertility, and Future Cardiovascular Risk: Implications for Mother and Child – Cardiovascular Drugs and Therapy (free)

 


Richard Lehman’s journal review / 10 July 2017

10 Jul, 2017 | 14:59h | UTC

Richard Lehman’s journal review / 10 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals

 


Free Online Course – Science of Exercise

10 Jul, 2017 | 22:09h | UTC

Just Started! Free Online Course. Science of Exercise – University of Colorado Boulder and Coursera

 


Management of Small Renal Masses

10 Jul, 2017 | 14:54h | UTC

Management of Small Renal Masses: American Society of Clinical Oncology Clinical Practice Guideline (free)

Summary: National Guideline Clearinghouse (free)

 


Beware of conflicting interests

10 Jul, 2017 | 14:58h | UTC

Beware of conflicting interests – Students 4 Best Evidence (free)

This is the sixth in a series of 34 blogs based on a list of ‘Key Concepts’ developed by an Informed Health Choices project team.

 


The rise of antibiotic-resistant infections threaten economies

10 Jul, 2017 | 14:55h | UTC

The rise of antibiotic-resistant infections threaten economies – Finantial Times (a few articles per month are free) (RT @greg_folkers see Tweet)

Related report: Drug-Resistant Infections: A Threat to Our Economic Future – World Bank (Free PDF) AND Infographic: Drug Resistant Infections: A Threat to Our Economic Future (free) AND News Release: By 2050, drug-resistant infections could cause global economic damage on par with 2008 financial crisis (free)

 


Mon, July 10 – 10 Stories of The Day!

10 Jul, 2017 | 00:01h | UTC

 

1 – Scientists warn that antibiotic-resistant gonorrhoea is on the rise – World Health Organization (free)

News Release: Antibiotic-resistant gonorrhoea on the rise, new drugs needed – Word Health Organization (free)

Commentaries: Untreatable gonorrhoea on the rise worldwide – Nature News (free) AND New data show gonorrhea increasingly resistant to antibiotics  STAT News (free) AND WHO warns of imminent spread of untreatable superbug gonorrhea – Reuters (free) AND Untreatable gonorrhoea ‘superbug’ spreading around world, WHO warns – The Guardian (free)

Related guideline: WHO guidelines for the treatment of Neisseria gonorrhoeae (free)

 

2 – Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study – The Lancet (free)

Invited commentary: Determining the burden of respiratory syncytial virus disease: the known and the unknown (free)

Commentary: Experts urge action to cut child deaths from deadly lung virus – University of Edinburgh, via EurekAlert (free)

“We estimated that globally in 2015, 33.1 million episodes of RSV-ALRI, resulted in about 3.2 million hospital admissions, and 59 600 in-hospital deaths in children younger than 5 years”. (RT @greg_folkers see Tweet)

 

3 – Breaking multiple unhealthy habits all at once has modest impact, but not always… – NIHR Signal (free)

Original article: Multiple Risk Behavior Interventions: Meta-analyses of RCTs – American Journal of Preventive Medicine (free)

“Review suggests it might be sensible to tackle smoking and diet separately, rather than at the same time” (RT @NIHR_DC see Tweet)

 

4 – Diabetes in sub-Saharan Africa: from clinical care to health policy – The Lancet Diabetes & Endocrinology (free registration required)

Invited commentary: The crisis of diabetes in sub-Saharan Africa (free registration required)

Commentaries: Alarm Bells Sound on Diabetes in Sub-Saharan Africa – Medscape (free registration required) AND Increasing diabetes burden in sub-Saharan Africa has potential to reverse health gains of recent years – News Medical (free)

“The growing burden of diabetes in sub-Saharan Africa will have huge consequences” (RT @Medscape see Tweet)

 

5 – Declining Risk of Sudden Death in Heart Failure – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Has Effective Medical Therapy Made The Benefit of ICDs Uncertain? – University of Glasgow News (free) AND Net value of pacemakers/defibrillators may no longer be so clear-cut – OnMedica (free) AND Sudden Death Declining in Heart Failure – Does the trend mean that ICDs are indicated less often? – CardioBrief (free)

 

6 – The Changing Face of Clinical Trials: Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both – New England Journal of Medicine (free)

See also: The Changing Face of Clinical Trials Series (free)

 

7 – Diabetes and Ramadan: Practical guidelines – Diabetes Research and Clinical Practice (free)

 

8 – Pretreatment fasting plasma glucose and insulin modify dietary weight loss success: results from 3 randomized clinical trials – American Journal of Clinical Nutrition (link to abstract – $ for full-text)

Commentaries: Fasting blood sugar, fasting insulin identified as new biomarkers for weight loss – University of Copenhagen, via ScienceDaily (free) AND Low-Fat or Low Carb for Weight Loss? It Depends on Your Glucose Metabolism – EbioMedicine (free)

Individuals with diabetes or pre-diabetes seem to have better results with low-carb diets.

 

9 – The Machines Are Getting Ready to Play Doctor – MIT Technology Review (free) (RT @EricTopol see Tweet 1 and Tweet 2)

Original article: Cardiologist-Level Arrhythmia Detection with Convolutional Neural Networks – Cornell University Library (free PDF)

In this study, a machine learning algorithm was better at diagnosing arrhythmias than cardiologists.

 

10 – Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review – Blood (link to abstract – $ for full-text)

Source: Direct Oral Anticoagulants for Heparin-Induced Thrombocytopenia – Journal Watch ($)

This literature review and observational study suggest direct oral anticoagulants (rivaroxaban, apixaban, dabigatran) are safe and effective for the treatment of Heparin-Induced Thrombocytopenia.

 


Free Online Course. Health for All Through Primary Health Care

9 Jul, 2017 | 00:52h | UTC

Just Started! Free Online Course. Health for All Through Primary Health Care – Johns Hopkins University and Coursera

 


Effective Care for High-Need Patients

10 Jul, 2017 | 14:53h | UTC

Effective Care for High-Need Patients: Opportunities for Improving Outcomes, Value, and Health (free PDF)

See also: News release (free) AND Executive summary (free PDF) AND Key Points (free PDF) AND Characteristics of Successful Care Models for High-Need Patients (free PDF)

Commentary: New NAM publication examines improving outcomes, reducing costs for ‘high-needs patients’ – National – National Academies of Sciences, Engineering, and Medicine, via EurekAlert (free)

See more resources on high-need, high-cost patients in our July 4th issue (see #2)

Source: STAT News Newsletter

“Nearly half of the nation’s spending on health care is driven by 5 percent of patients, and improving health outcomes and curbing spending in health care will require identifying who these high-needs patients are and providing coordinated services” (from EurekAlert)

 


The weird power of the placebo effect, explained

9 Jul, 2017 | 00:47h | UTC

The weird power of the placebo effect, explained – VOX (free)

Related: Placebos can work even when patients know what they are – World Economic Forum (free)

 


How to make global universal healthcare a reality

9 Jul, 2017 | 00:49h | UTC

Viewpoint: How to make global universal healthcare a reality – The Guardian (free)

“What is the best model to bring healthcare to all? Our experts offer 11 ideas for increasing access to health services around the world”

 


Breaking multiple unhealthy habits all at once has modest impact

9 Jul, 2017 | 00:41h | UTC

3 – Breaking multiple unhealthy habits all at once has modest impact, but not always… – NIHR Signal (free)

Original article: Multiple Risk Behavior Interventions: Meta-analyses of RCTs – American Journal of Preventive Medicine (free)

“Review suggests it might be sensible to tackle smoking and diet separately, rather than at the same time” (RT @NIHR_DC see Tweet)

 


Global burden of respiratory syncytial virus in young children

9 Jul, 2017 | 00:42h | UTC

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study – The Lancet (free)

Invited commentary: Determining the burden of respiratory syncytial virus disease: the known and the unknown (free)

Commentary: Experts urge action to cut child deaths from deadly lung virus – University of Edinburgh, via EurekAlert (free)

“We estimated that globally in 2015, 33.1 million episodes of RSV-ALRI, resulted in about 3.2 million hospital admissions, and 59 600 in-hospital deaths in children younger than 5 years”. (RT @greg_folkers see Tweet)

 


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