Archives
Richard Lehman’s journal reviews – 3 April 2018
6 Apr, 2018 | 01:44h | UTCRichard Lehman’s journal reviews, 3 April 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Perspective: ‘faith healing’ and chest pain
6 Apr, 2018 | 01:48h | UTCRelated: More Controversy Over Major Cardiology Clinical Trial – Cardiobrief (free) AND Cardiology World Erupts Into Controversy Over Change In Major Clinical Trial – Cardiobrief (free) AND Moving the Goalposts Into Unblinded Territory – Circulation: Cardiovascular Quality and Outcomes (free)
Meta-analysis: acute chest pain evaluation using coronary CT angiography
6 Apr, 2018 | 01:43h | UTCAcute chest pain evaluation using coronary computed tomography angiography compared with standard of care: a meta-analysis of randomised clinical trials – Heart (link to abstract – $ for full-text)
See commentary in: Articles of the month (March 2018) – First10EM (free)
Se related meta-analysis published recently with similar results: Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials – The BMJ (free)
“Bottom line: In the RCTs we have to date, CCTA demonstrate no benefit, but leads to an increase in unnecessary invasive procedures” (from First10EM).
Meta-analysis: migraine and the risk of cardiovascular and cerebrovascular events
6 Apr, 2018 | 01:41h | UTCCommentary: Migraines tied to higher risk for stroke, MI in large meta-analysis – Univadis (free registration required)
Meta-analysis: effects of oxygen therapy in patients with suspected acute myocardial infarction
6 Apr, 2018 | 01:39h | UTCEffects of supplemental oxygen therapy in patients with suspected acute myocardial infarction: a meta-analysis of randomised clinical trials – Heart (link to abstract – $ for full-text)
Related guideline: BTS Guideline for oxygen use in healthcare and emergency settings – British Thoracic Society (free)
“These findings from eight RCTs support departing from the usual practice of administering oxygen in normoxaemic patients”.
Review: management of left main coronary artery disease
6 Apr, 2018 | 01:36h | UTCReview: Management of Left Main Coronary Artery Disease – Journal of the American Heart Association (free for a limited period)
Cohort study: socioeconomic status, non-communicable disease risk factors, and walking speed in older adults
6 Apr, 2018 | 01:37h | UTC“New work in @bmj_latest shows poverty increases ageing. Measured by walking speed. 60 y.o. men of lower social class walk like 66 y.o. men of higher social class. As important as physical inactivity, obesity or diabetes. Worse than smoking”. (via @astaines see Tweet)
Randomized trial: nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma
6 Apr, 2018 | 01:34h | UTCNivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma – NEJM (link to abstract – $ for full-text)
Quick Take Video Summary: Sunitinib or Nivolumab plus Ipilimumab for Renal-Cell Carcinoma (free)
“Overall survival and objective response rates were significantly higher with nivolumab plus ipilimumab”.
Research: postnatal Zika virus infection is associated with abnormalities in the brain of infant macaques
6 Apr, 2018 | 01:23h | UTCPostnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques – Science Translational Medicine (link to abstract – $ for full-text)
Commentaries: Monkey study suggests Zika infection in infancy could cause brain damage – STAT (free) AND Zika Exposure Even after Birth May Lead to Brain Damage – Scientific American (free)
Observational study: time to endovascular treatment and outcome in acute ischemic stroke
6 Apr, 2018 | 01:30h | UTCTime to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results – Circulation (link to abstract – $ for full-text)
Commentary: Time to endovascular therapy predicted functional outcome after stroke in registry study – ACP Hospitalist (free)
“Every hour of delay from stroke onset to the start of endovascular therapy resulted in a 5.3% decreased probability of functional independence” (from ACP Hospitalist)
Cohort study: change in overweight from childhood to early adulthood and risk of type 2 diabetes
6 Apr, 2018 | 01:32h | UTCChange in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Heavy kids who normalize weight in childhood can avoid extra diabetes risk – Reuters (free) AND Normalizing Weight By Puberty May Drop Diabetes Risk Later – Medscape (free registration required)
AHA scientific statement: assessment and promotion of physical activity in healthcare settings
6 Apr, 2018 | 01:20h | UTCCommentary: Promoting Physical Activity in Routine Health Care: Time to Walk the Talk (free)
Top Ten Things to Know: Routine Assessment and Promotion of Physical Activity in Healthcare Settings (free PDF)
Meta-analysis: safety of early discharge after primary angioplasty in low-risk patients with STEMI
6 Apr, 2018 | 01:13h | UTCSafety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction: A meta-analysis of randomised controlled trials – European Journal of Preventive Cardiology (link to abstract – $ for full-text)
“The findings of this meta-analysis suggested that the early discharge strategy after successful primary angioplasty is safe among selected low-risk STEMI patients. A shorter hospital stay could benefit both the patients and the healthcare systems”.
Cohort studies: associations of bariatric surgery with changes in interpersonal relationship status
6 Apr, 2018 | 01:28h | UTCAssociations of Bariatric Surgery With Changes in Interpersonal Relationship Status: Results From 2 Swedish Cohort Studies – JAMA Surgery (free for a limited period)
Invited commentary: Relationship Status After Bariatric Surgery: It’s Complicated (free for a limited period)
Commentaries: Relationship changes after bariatric surgery – University of Gothenburg, via EurekAlert (free) AND Big weight loss may bring big relationship changes – UPI (free)
Cohort study: preconception blood pressure levels and reproductive outcomes
6 Apr, 2018 | 01:21h | UTCPreconception Blood Pressure Levels and Reproductive Outcomes in a Prospective Cohort of Women Attempting Pregnancy – Hypertension (link to abstract – $ for full-text)
Commentaries: Higher blood pressure before pregnancy may increase miscarriage risk – American Heart Association, via ScienceDaily (free) AND High blood pressure before pregnancy linked to heightened miscarriage risk – OnMedica (free) AND Slightly high blood pressure before pregnancy tied to miscarriage risk – Reuters (free) AND Higher Blood Pressure Before Conception Tied to Miscarriage – MedPage Today (free registration required)
Guideline: presentation of surveillance data
6 Apr, 2018 | 01:11h | UTC
Guideline: management of uveitis associated with juvenile idiopathic arthritis
6 Apr, 2018 | 01:14h | UTC
Guideline: palliative thoracic radiation therapy for non-small cell lung cancer
6 Apr, 2018 | 01:10h | UTCCommentaries: Updated ASTRO guideline for palliative lung radiation now recommends concurrent chemotherapy for some stage III patients – eCancer News (free) AND ASTRO updates lung radiation guideline for non-small cell lung cancer patients – Health Imaging (free)
Guideline: irritable bowel syndrome
6 Apr, 2018 | 01:07h | UTC
WHO guideline: integrated care for older people
6 Apr, 2018 | 01:09h | UTC
ASCO guideline: anticancer therapy in metastatic non-castrate prostate cancer
6 Apr, 2018 | 01:05h | UTC
Perspective: time to sink the two-canoe argument
6 Apr, 2018 | 01:06h | UTCTime to Sink the Two-Canoe Argument – NEJM Catalyst (free)
Research: the opportunity cost of animal based diets exceeds all food losses
6 Apr, 2018 | 01:03h | UTC
Perspective: surgical care – an overlooked entity in health systems
6 Apr, 2018 | 01:04h | UTCSurgical care – an overlooked entity in health systems – The World Bank (free)
Review: Acromegalic cardiomyopathy
6 Apr, 2018 | 01:01h | UTCAcromegalic cardiomyopathy: Epidemiology, diagnosis, and management – Clinical Cardiology (free)