Archives
Thu, April 12 – 10 Stories of The Day!
12 Apr, 2018 | 00:02h | UTC
1 – Zika Virus Shedding in Semen of Symptomatic Infected Men – New England Journal of Medicine (free)
Editorial: Virus in Semen and the Risk of Sexual Transmission (free)
Commentaries: New findings on Zika virus in semen may alter CDC guidance – CIDRAP (free) AND Study suggests risk of sexual transmission of Zika may dissipate quickly – STAT (free)
Source: New Clinical Practice Guidelines, April 2018 Edition – Medscape (free registration required)
Related guideline: Clinical practice guideline: management of acute pancreatitis – Canadian Journal of Surgery (free)
3 – Guideline: Lyme disease – National Institute for Health and Care Excellence (free)
News release: New advice will help doctors spot and treat Lyme disease early, says NICE (free)
Commentaries: Don’t lose sleep over reports that one bad night can spark dementia – NHS Choices (free) AND One night of sleep deprivation leads to increase in Alzheimer’s protein – New Atlas (free) AND Expert reaction to study investigating sleep deprivation and amyloid build up – Science Media Centre (free)
5 – Long-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Study confirms link between traumatic brain injury and dementia – UW Medicine, via EurekAlert (free) AND Traumatic brain injury increases risk of dementia – OnMedica (free) AND Brain injury may increase dementia risk – NHS Choices (free)
Related articles: Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free) AND Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football – JAMA (free)
Commentaries: Scientists Push Plan To Change How Researchers Define Alzheimer’s – NPR (free) AND Researchers Propose New Alzheimer’s Definition Based on Biomarkers – MedPage Today (free registration required) AND New biological research framework for Alzheimer’s seeks to spur discovery – NIH / National Institute on Aging, via EurekAlert (fee)
7 – Guideline: Evaluation and Management of Testosterone Deficiency – American Urological Association (free)
Commentary: AUA: New Guidelines for Diagnosis, Management of Testosterone Deficiency – MPR (free)
Related Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Commentaries: FDA’s Proposed Sodium Reduction Plan Could Have a Big Impact, Analysis Suggests – TCTMD (free) AND US FDA sodium reformulation targets projected to save lives and costs – PLOS, via EurekAlert (free) AND Study highlights the health and economic benefits of a US salt reduction strategy – University of Liverpool (free)
9 – Investing in non-communicable disease prevention and management to advance the Sustainable Development Goals – The Lancet (free registration required)
See complete series: The Lancet Taskforce on NCDs and economics (free registration required for articles and commentaries)
“Economic case to #BeatNCDs: benefit-cost ratio of investing in prevention and treatment of #NCDs is 5.6 for economic returns – 10.9 if social returns are included” (via @TheLancet see Tweet)
10 – Effectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary: Preventive cognitive therapy is an effective alternative and addition to antidepressants for preventing depression relapse, study finds – ACP Internist (free) AND Preventive Cognitive Therapy Helps Limit Depression Recurrence – NEJM Physician’s First Watch (free) AND Depression: preventive cognitive therapy improves outcome in recurrent depression – Univadis (free registration required)
Review: management of patients with aortic valve stenosis
11 Apr, 2018 | 02:10h | UTCManagement of Patients With Aortic Valve Stenosis – Mayo Clinic Proceedings (free)
Cohort study: sleep deficiency and motor vehicle crash risk
11 Apr, 2018 | 02:07h | UTCCommentary: Sleep deficiency increases risk of a motor vehicle crash – Brigham and Women’s Hospital, via ScienceDaily (free)
“Study finds that sleep deficiency due to either sleep apnea or insufficient sleep duration is strongly associated with motor vehicle crashes, regardless of one’s self-reported sleepiness level” (from ScienceDaily)
Randomized, crossover trial: metabolic recovery from heavy exertion following banana compared to sugar beverage
11 Apr, 2018 | 02:09h | UTCCommentary: Bananas vs. Sports Drinks? Bananas Win in Study – The New York Times (10 articles per month are free)
Machine learning: identification of intracranial hemorrhage on CT scans of the head
11 Apr, 2018 | 01:48h | UTCAdvanced machine learning in action: identification of intracranial hemorrhage on computed tomography scans of the head with clinical workflow integration – NPJ Digital Medicine (free) (via @EricTopol see Tweet)
Longitudinal study: lasting cognitive gains from meditation
11 Apr, 2018 | 02:01h | UTCCommentary: Seven-year follow-up shows lasting cognitive gains from meditation – University of California, via ScienceDaily (free)
ACR guideline: breast cancer screening in women at higher-than-average risk
11 Apr, 2018 | 02:05h | UTCCommentaries: ACR Recommends More Aggressive Breast Cancer Screening for Higher-Than-Average-Risk Women – Imaging Technology News (free) AND New ACR/SBI Breast Cancer Screening Guidelines Call for Significant Changes to Screening Process – American College of Radiology, via NewsWise (free)
See related guideline with a more conservative approach: Breast Cancer: Screening – U.S. Preventive Services Task Force (free)
ECCO essential requirements for quality cancer care: Melanoma
11 Apr, 2018 | 01:39h | UTC
Consensus statement: endovascular therapy of acute ischemic stroke
11 Apr, 2018 | 02:03h | UTCRelated guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF)
ECCO essential requirements for quality cancer care: Oesophageal and gastric cancer
11 Apr, 2018 | 01:38h | UTC
Consensus: prevention and treatment of postoperative pulmonary infection in esophageal cancer patients
11 Apr, 2018 | 01:41h | UTC
ACC/AHA clinical performance and quality measures for cardiac rehabilitation
11 Apr, 2018 | 01:36h | UTCCommentary: New ACC/AHA Performance, Quality Measures for Cardiac Rehab – Medscape (free registration required)
Cross-sectional study: residential greenness and prevalence of major depressive disorders
11 Apr, 2018 | 01:24h | UTC
Randomized controlled trial: acupuncture versus titrated morphine in acute renal colic
11 Apr, 2018 | 01:19h | UTCSource: EvidenceAlerts
Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence
11 Apr, 2018 | 01:34h | UTCEffectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary: Preventive cognitive therapy is an effective alternative and addition to antidepressants for preventing depression relapse, study finds – ACP Internist (free) AND Preventive Cognitive Therapy Helps Limit Depression Recurrence – NEJM Physician’s First Watch (free) AND Depression: preventive cognitive therapy improves outcome in recurrent depression – Univadis (free registration required)
Retrospective longitudinal analysis: excess oxygen may increase mortality in ARDS
11 Apr, 2018 | 01:17h | UTCOxygen Exposure Resulting in Arterial Oxygen Tensions Above the Protocol Goal Was Associated With Worse Clinical Outcomesin Acute Respiratory Distress Syndrome – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: ARDS mortality rises with excess oxygen – Univadis (free registration required)
Tue, April 10 – 10 Stories of The Day!
10 Apr, 2018 | 00:02h | UTC
1 – Clinical Practice Guideline: Iron Deficient Anemia – Toward Optimized Practice (TOP) (free PDF)
See also: Summary and Algorithm (free PDF)
Related: see all TOP Clinical Practice Guidelines, a practical resource for Family Physicians at the point of care.
2 – Dialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs – JAMA Internal Medicine (free for a limited period)
Invited commentary: Appropriate Time for Chronic Dialysis Initiation: A Cause for Humility (free for a limited period)
Related articles: Treatment decisions for older adults with advanced chronic kidney disease – BMC Nephrology (free) AND Timing of Dialysis Initiation – What Has Changed Since IDEAL? – Seminars in Nephrology (free)
3 – Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related article: Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentaries: Three-quarters of COPD cases are linked to childhood risk factors that are exacerbated in adulthood – The Lancet, via ScienceDaily (free) AND Early intervention may minimise later lung problems – The Melbourne Newsroom (free) AND COPD Risk Factors Evident Early in Life – NEJM Physician’s First Watch (free)
4 – Seminar: Malaria – The Lancet (free registration required)
5 – Perspective: Many People Taking Antidepressants Discover They Cannot Quit – The New York Times (10 articles per month are free)
Commentaries: Quitting Facebook can reduce stress – University of Queensland (free) AND Giving up Facebook leads to a drop in the stress-related hormone cortisol, study finds – PsyPost (free) AND Does Quitting Facebook Really Make You Less Happy? Probably Not – Forbes (free) AND Want to de-stress? Delete Facebook, study suggests – Medical News Today (free)
7 – Alpha-blockers as medical expulsive therapy for ureteral stones – Cochrane Library (link to abstract – $ for full-text)
Summary: Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease – Cochrane Library (free)
9 – AHA Policy Statement: Projected Costs of Informal Caregiving for Cardiovascular Disease: 2015 to 2035 – Circulation (free)
Commentary: Skyrocketing Costs of CVD Will Be Amplified by Informal Caregiving: AHA – TCTMD (free)
10 – Pharmaceutical Industry Payments and Oncologists’ Selection of Targeted Cancer Therapies in Medicare Beneficiaries – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Payments to Doctors Linked to Prescription Practices for Two Cancer Types – University of North Carolina (free) AND Pharma Dollars Appear to Sway Oncologist Rx Habits – MedPage Today (free registration required)
Perspective: Patient Advocacy Groups Take In Millions From Drugmakers. Is There A Payback?
11 Apr, 2018 | 01:13h | UTCPatient Advocacy Groups Take In Millions From Drugmakers. Is There A Payback? – Kaiser Health News (free)
Wed, April 11 – 10 Stories of The Day!
11 Apr, 2018 | 00:07h | UTC
Editorial: Toward a United States of Health: Implications of Understanding the US Burden of Disease (free)
Author interview: US Burden of Diseases, Injuries, and Disease Risk Factors, 1990-2016 (free)
Commentaries: Warning Signs: New US Health Study Reveals ‘Dangerous Disparities’ among States – Institute for Health Metrics and Evaluation (free) AND The states where disease and death are highest: A visual guide – CNN (free)
“NEW global burden of disease study on US health is most comprehensive state-by-state health assessment ever undertaken & includes estimates for all 50 states & Washington DC & the nation overall” (via @IHME_UW see Tweet)
2 – Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study – Circulation (free PDF for a limited period)
Commentaries: Outrunning Your Genes: Exercise Offsets CVD Events Among High-Risk Subjects – TCTMD (free) AND When heart disease runs in the family, exercise tied to lower risk – Reuters (free)
3 – Honey for acute cough in children – Cochrane Library (link to abstract – $ for full-text)
Summary: Honey for acute cough in children – Cochrane Library (free)
“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”
Commentary: Pasta unlikely to cause weight gain as part of a healthy diet – NHS Choices (free)
Commentaries: Weight loss is an important predictor of cancer – University of Oxford (free)
Source: Global Health NOW Newsletter
9 – EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
10 – Associations Between Brain Structure and Connectivity in Infants and Exposure to Selective Serotonin Reuptake Inhibitors During Pregnancy – JAMA Pediatrics (free for a limited period)
Author interview: Associations Between SSRI Exposure During Pregnancy and MRI-Assessed Brain Structure and Connectivity in Infants (free)
Commentaries: We’re beginning to learn how moms’ antidepressants can affect fetuses – VOX (free) AND MRI study finds prenatal exposure to certain antidepressants may alter brain development – Health Imaging (free) AND SSRI use in pregnancy may affect fetal brain development – OnMedica (free) AND Antidepressants in pregnancy tied to changes in babies’ brains – Reuters (free)
Perspective: the scientific paper is obsolete
11 Apr, 2018 | 01:18h | UTCThe Scientific Paper Is Obsolete – The Atlantic (free)
Fri, April 6 – 10 Stories of The Day!
6 Apr, 2018 | 02:34h | UTC
Commentary: New guidance for safe opioid prescribing for hospitalized patients with acute pain – Beth Israel Deaconess Medical Center, via EurekAlert (free)
2 – Guideline: Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine (free)
3 – Guideline: Interventional Spine and Pain Procedures in Patients on Antiplatelet and Anticoagulant Medications – American Society of Regional Anesthesia and Pain Medicine (free)
4 – Meta-analysis: Nasal vs Oronasal CPAP for OSA Treatment – CHEST (free)
Source: EvidenceAlerts
5 – Management of Patients With Aortic Valve Stenosis – Mayo Clinic Proceedings (free)
Commentary: Bananas vs. Sports Drinks? Bananas Win in Study – The New York Times (10 articles per month are free)
Commentary: Sleep deficiency increases risk of a motor vehicle crash – Brigham and Women’s Hospital, via ScienceDaily (free)
“Study finds that sleep deficiency due to either sleep apnea or insufficient sleep duration is strongly associated with motor vehicle crashes, regardless of one’s self-reported sleepiness level” (from ScienceDaily)
Commentaries: ACR Recommends More Aggressive Breast Cancer Screening for Higher-Than-Average-Risk Women – Imaging Technology News (free) AND New ACR/SBI Breast Cancer Screening Guidelines Call for Significant Changes to Screening Process – American College of Radiology, via NewsWise (free)
See related guideline with a more conservative approach: Breast Cancer: Screening – U.S. Preventive Services Task Force (free)
Related guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF)
Commentary: Seven-year follow-up shows lasting cognitive gains from meditation – University of California, via ScienceDaily (free)
Mon, April 9 – 10 Stories of The Day!
9 Apr, 2018 | 01:25h | UTC
1 – World Health Day (7 April 2018) – World Health Organization (free resources)
See also: Campaign Essentials / Key Messages / and WHO’s Universal Health Coverage Website
WHO’s theme for this year world health day is Universal Health Coverage. “Health is a human right. It’s time for Universal Health Coverage for everyone, everywhere”. (via @WHO see Tweet)
2 – New Series from The Lancet Journals: The Lancet Taskforce on NCDs and economics (free registration required for all articles and commentaries)
Commentaries: Tax sugar, alcohol and tobacco to help the poor, say experts – The Guardian (free) AND Taxes on soft drinks, alcohol and tobacco are of most benefit to the poor – Imperial College London (free)
See also: To Improve Global Health, Tax the Things that are Killing Us (free policies, articles and commentaries)
4 – Physiotherapy education before major abdominal surgery reduces lung complications – NIHR Signal (free)
See original article: Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)
5 – Guideline summaries: 2018 ESC Guidelines for Diagnosis and Management of Syncope – American College of Cardiology (free) AND Practical Instructions for the 2018 ESC Syncope Guidelines – American College of Cardiology (free)
Original Documents: 2018 ESC Guidelines for the diagnosis and management of syncope (free) AND Practical Instructions for the 2018 ESC Guidelines for the diagnosis and management of syncope (free)
6 – “A Guide to Gutsy Living”: Patient-Driven Development of a Pediatric Ostomy Toolkit – Pediatrics (free)
Commentary: New guide helps kids, adolescents living with ostomies – Reuters (free)
7 – Percutaneous vertebroplasty for osteoporotic vertebral compression fracture – Cochrane Library (link to abstract – $ for full-text)
Summary: Featured Review: Vertebroplasty for treating spinal fractures due to osteoporosis – Cochrane Library (free)
“High quality evidence shows that vertebroplasty does not provide more clinically important benefits than placebo but may cause people harm”.
8 – EASL Clinical Practice Guidelines on hepatitis E virus infection – Journal of Hepatology (free)
10 – Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion – New England Journal of Medicine (link to abstract – $ for full-text) (see Visual Abstract)
Commentary: Outpatient talc administration improves malignant effusion outcomes – Chest Physician (free)
Observational study: characteristics of infant deaths during sleep while under nonparental supervision
6 Apr, 2018 | 01:52h | UTCCommentaries: Babies At Risk Of Being Put In Unsafe Sleep Positions By Babysitters And Relatives, Study Suggests – HuffPost (free) AND Infant death study reveals dangerous sleep practices among babysitters, relatives, others – University of Virginia Health System, via ScienceDaily (free)
Related Guideline: SIDS and Other Sleep-Related Infant Deaths: Updated 2016 Recommendations for a Safe Infant Sleeping Environment – Task Force on Sudden Infant Death Syndrome, American Academy of Pediatrics (free)
Perspective: some acutely ill patients are getting treated at home
6 Apr, 2018 | 01:49h | UTCHospitals are germy, noisy places. Some acutely ill patients are getting treated at home instead – The Washington Post (a few articles per month are free)
Source: STAT Newsletter
Research: negative wealth shock associated with increased all-cause mortality
6 Apr, 2018 | 01:47h | UTCAssociation of a Negative Wealth Shock With All-Cause Mortality in Middle-aged and Older Adults in the United States – JAMA (free for a limited period)
Commentaries: Financial Ruin Can Be Hazardous To Your Health – NPR (free) AND Losing your nest egg can kill you – Northwestern University, via ScienceDaily (free)
“People have a 50 percent higher risk of death if they suffer a shocking financial loss” (via ScienceDaily)


