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Randomized Trial: Effectiveness of Text Message Based, Diabetes Self-management Support

24 May, 2018 | 22:19h | UTC

Effectiveness of text message based, diabetes self management support programme (SMS4BG): two arm, parallel randomised controlled trial – The BMJ (free)

Commentaries: The potential of mobile health—reaching those in need – The BMJ Opinion (free)

 


Research: Antibiotic Resistance Increases with Local Temperature

24 May, 2018 | 22:28h | UTC

Antibiotic resistance increases with local temperature – Nature Climate Change (free for a limited period)

Commentaries: A Warming Climate May Produce More Drug-Resistant Infections – Scientific American (free) AND Study finds antibiotic resistance rise tied to hotter temps – CIDRAP (free)

 


Introduction to Systematic Review and Meta-analysis

24 May, 2018 | 22:21h | UTC

Introduction to systematic review and meta-analysis – Korean Journal of Anesthesiology (free)

Source: Critical Care Reviews Newsletter

 


Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation

23 May, 2018 | 12:48h | UTC

Association of Burden of Atrial Fibrillation with Risk of Ischemic Stroke in Adults With Paroxysmal Atrial Fibrillation: The KP-RHYTHM Study – JAMA Cardiology (free)

Commentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)

 


Opinion: “Don’t Put That in My Heart Until You’re Sure It Really Works”

23 May, 2018 | 12:46h | UTC

Don’t Put That in My Heart Until You’re Sure It Really Works – The New York Times (10 articles per month are free)

Commentary: Cardiologist wants more rigorous testing before devices, techniques are adopted – Cardiovascular Business (free)

See also: commentaries (PRO and Con) on the CABANA Trial

 


Thu, May 24 – 10 Stories of The Day!

24 May, 2018 | 00:05h | UTC

 

1 – A Pragmatic Trial of E-Cigarettes, Incentives, and Drugs for Smoking Cessation – New England Journal of Medicine (free)

Commentaries: Money a better motivator to stop smoking than free e-cigs or quit aids – Reuters (free) AND E-cigarettes aren’t better at helping smokers quit than other strategies – Journalist’s Resource (free) AND For Smoking Cessation, Money Whispers Louder than Nicotine Replacement – MedPage Today (free registration required)

“Trial finds financial incentives most effective – but nothing very effective” (from MedPage Today)

 

2 – A Randomized Trial of a Family-Support Intervention in Intensive Care Units – New England Journal of Medicine (free)

Editorial: Nurse-Led Communication in the Intensive Care Unit (free)

Commentary: Team Approach to Support Families Improves ICU Patient-Centered Care and Lowers Costs – University of Pittsburg (free)

 

3 – Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology – Journal of Clinical Oncology (free)

 

4 – Advocating for Life Support Training of Children, Parents, Caregivers, School Personnel, and the Public – Pediatrics (free)

Summary: Advocating for Life Support Training of Children, Parents, Caregivers, School Personnel, and the Public (free)

News Release: AAP policy says more people need access to life support training, AEDs (free)

Commentary: AAP: Children can be educated in assisting those in cardiac arrest – Healio (free registration required)

 

5 – Estimating the Association of the 2017 and 2014 Hypertension Guidelines With Cardiovascular Events and Deaths in US Adults: An Analysis of National Data – JAMA Cardiology (free for a limited period)

Author Interview: Association of the 2014 and 2017 Hypertension Guidelines With Cardiovascular Events and Deaths in US Adults (free)

Commentary: Under 2017 Guideline, More Than 105 Million Americans Have Hypertension – AJMC (free)

The researchers estimated risk reductions of CVD and all-cause mortality, as well as associated harms from therapy, assuming the entire US adult population achieved guideline-recommended systolic BP treatment goals.

 

6 – Perspective: Ten dubious beliefs in neurocritical care – PulmCrit (free)

 

7 – A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill – Critical Care Medicine (free for a limited period)

Source: Critical Care Reviews Newsletter

 

8 – Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial – The Lancet (link to abstract – $ for full-text)

Related Article: Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial (link to abstract – $ for full-text)

Commentaries: Two Sham-Controlled Renal Denervation Studies Offer Hope in Hypertension – TCTMD (free) AND Renal denervation linked to significant drops in blood pressure – Cardiovascular Business (free) AND Novel Renal Denervation Catheters Showing Modest BP Reductions – MedPage Today (free registration required)

 

9 – Incidence and cost of medication harm in older adults following hospital discharge: A multicentre prospective study in the UK – British Journal of Clinical Pharmacy (free PDF)

Commentaries: Medication-related harm is common in older adults after hospital discharge – OnMedica (free) AND Medication-related harm found to be common among older adults, but preventable  – News Medical (free)

 

10 – Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality – Heart (free)

Commentaries: Avoiding the car for travel could significantly lower risk of illness and death – BMJ, via EurekAlert (free) AND Ditching the car may reduce your risk of dying from heart disease and stroke by almost a third – The Conversation (free)

 


Review: Managing Depression in Patients with CAD

23 May, 2018 | 12:47h | UTC

Identifying and managing depression in patients with coronary artery disease – Journal of the American Academy of Pas (free)

Commentaries: Depression in Patients With CAD – American College of Cardiology (free) AND Early Depression Diagnosis is Deadly Serious for Patients with Coronary Artery Disease – Florida State University, via NewsWise (free)

 


Disease Outbreak News: WHO Supports Ebola Vaccination of High Risk Populations in the DRC

23 May, 2018 | 12:44h | UTC

WHO supports Ebola vaccination of high risk populations in the Democratic Republic of the Congo – World Health Organization (free)

Commentaries: Experimental Ebola Vaccinations, Considered ‘Paradigm Shift,’ Begin In Congo – NPR (free) AND Ebola vaccine drive launches in DRC as cases rise to 49 – CIDRAP (free) AND Congo begins giving experimental Ebola vaccine to medics – Reuters (free)

See also: Frequently asked questions on Ebola virus disease vaccine – World Health Organization (free)

“Health workers operating in affected areas in the Democratic Republic of the Congo are being vaccinated today and community outreach has started to prepare for the ring vaccination” (via @WHO see Tweet)

 


Review: Autism Spectrum Disorder

23 May, 2018 | 12:46h | UTC

Autism spectrum disorder: advances in diagnosis and evaluation – The BMJ (free for a limited period)

 


Richard Lehman’s weekly journal review – 21 May 2018

23 May, 2018 | 12:45h | UTC

Richard Lehman’s weekly journal review, 21 May 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Randomized Trial: Procalcitonin-Guided Therapy Did Not Reduce the Use of Antibiotics

23 May, 2018 | 12:43h | UTC

Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection – New England Journal of Medicine (free)

Commentaries: Procalcitonin-Guided Care Doesn’t Reduce Antibiotics for Lower Respiratory Tract Infection – NEJM Journal Watch (free) AND Infection blood test of limited value in reducing antibiotic use – MedicalXpress (free)

 


Guideline: Clinical use of Resuscitative Endovascular Balloon Occlusion of the Aorta

23 May, 2018 | 12:44h | UTC

Joint statement from the American College of Surgeons Committee on Trauma (ACS COT) and the American College of Emergency Physicians (ACEP) regarding the clinical use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) (free)

Commentary: EMCrit Guest Post – The good, the bad, and the ugly of the Joint Statement on REBOA by Zaffer Qasim (free)

Source: Critical Care Reviews Newsletter

 


Randomized Controlled Trial: Dupilumab in Glucocorticoid-Dependent Severe Asthma

23 May, 2018 | 12:39h | UTC

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma – New England Journal of Medicine (free)

Related Article: Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma – New England Journal of Medicine (free)

Editorial: New Biologics for Asthma (free)

Commentary: Dupilumab Improves Severe Asthma – NEJM Physician’s First Watch (free)


Comparative Effectiveness Trial: Chiropractic Care Improves Disability in Low Back Pain

23 May, 2018 | 12:38h | UTC

Effect of Usual Medical Care Plus Chiropractic Care vs Usual Medical Care Alone on Pain and Disability Among US Service Members With Low Back Pain: A Comparative Effectiveness Clinical Trial – JAMA Network Open (free)

Commentaries: Innovating to Improve Care for Low Back Pain in the Military: Chiropractic Care Passes Muster – JAMA Network Open (free) AND Chiropractic Care Improves Usual Management for Low Back Pain – Medscape (free registration required) AND Adding chiropractic to back pain care may reduce disability – Reuters (free)

 


Cohort Study: Grip Strength and All-Cause Mortality

23 May, 2018 | 12:37h | UTC

Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants – The BMJ (free)

Commentary: Strong grip may predict longer life at all ages – Reuters (free)

 


New BMJ Series: Universal Health Coverage

23 May, 2018 | 12:35h | UTC

“The BMJ in partnership with The Harvard Global Health Institute are launching a collection of articles that will explore how to achieve effective Universal Health Coverage (UHC)”

– Home

– Analysis: Rethinking assumptions about delivery of healthcare: implications for universal health coverage (free)

– Opinion: Non-communicable diseases must be part of Universal Health Coverage (free)

– Opinion: Ensuring effective investments in Universal Health Coverage at the national level

– Opinion: Paying and investing in community health workers accelerates universal health coverage

 


Perspective: How PrEP to Prevent HIV May be Fueling a Rise in Other STDs

23 May, 2018 | 12:36h | UTC

How PrEP, the pill to prevent HIV, may be fueling a rise in other STDs – Vox (free)

Original Meta-Analysis: Effects of Pre-exposure Prophylaxis for the Prevention of Human Immunodeficiency Virus Infection on Sexual Risk Behavior in Men Who Have Sex With Men: A Systematic Review and Meta-analysis – Clinical Infectious Diseases (link to abstract – $ for full-text)

See also: Guidelines on HIV Pre-exposure Prophylaxis (all free)

 


Cohort Study: Egg Consumption and Cardiovascular Disease

23 May, 2018 | 12:32h | UTC

Associations of egg consumption with cardiovascular disease in a cohort study of 0.5 million Chinese adults – Heart (free)

Commentaries: BMJ’s scrambled message on eggs and heart disease: a recipe for rotten news coverage – Health News Review (free) AND Expert reaction to eggs and CVD – Science Media Centre (free) AND No, Eating Eggs Will NOT Protect You From Cardiovascular Death – The Methods Man (free)

 


Pro/Con Debate: CTA as the Initial Test in Stable Angina

23 May, 2018 | 12:33h | UTC

Pro: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)

Con: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)

 


Meta-Analysis: Corticosteroids for Patients with Septic Shock

23 May, 2018 | 12:28h | UTC

Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis – Critical Care Medicine (free for a limited period)

Source: Critical Care Reviews Newsletter

“In adults with septic shock treated with low dose corticosteroids, short- and longer-term mortality are unaffected, adverse events increase, but duration of shock, mechanical ventilation and ICU stay are reduced”.

 


Guideline: Use of Atraumatic Needles in All Patients Undergoing Lumbar Puncture

23 May, 2018 | 12:32h | UTC

Rapid Recommendations: Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline – The BMJ (free)

“We issue a strong recommendation for use of atraumatic needles in all patients (adults and children) undergoing lumbar puncture because they decrease complications and are no less likely to work than conventional needles”

 


Studies: More vs Less Frequent Follow-up Testing and Colorectal Cancer Outcomes

23 May, 2018 | 12:31h | UTC

Effect of More vs Less Frequent Follow-up Testing on Overall and Colorectal Cancer–Specific Mortality in Patients With Stage II or III Colorectal Cancer: The COLOFOL Randomized Clinical Trial – JAMA (free for a limited period)

Related Study: Association Between Intensity of Posttreatment Surveillance Testing and Detection of Recurrence in Patients With Colorectal Cancer (free for a limited period)

Commentaries: Surveillance intensity not associated with earlier detection of recurrence or improved survival in colorectal cancer – MedicalXpress (free) AND CRC: No Increase in Survival with Stepped-Up Surveillance – MedPage Today (free registration required) AND CRC recurrence surveillance studies: No benefit to high-intensity strategy – Oncology Practice (free)

 


Meta-Analysis: Aldosterone Antagonists for ST-Segment Elevation Myocardial Infarction Without Heart Failure

23 May, 2018 | 12:28h | UTC

Aldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Mineralocorticoid Receptor Antagonists in ST-Segment Elevation Myocardial Infarction – JAMA Internal Medicine (free for a limited period)

Aldosterone antagonists are beneficial for patients with STEMI and reduced ejection fraction. This meta-analysis suggests that patients with STEMI and LVEF greater than 40% or without heart failure also have improved outcomes with aldosterone antagonists.

 


Research: Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection

23 May, 2018 | 12:23h | UTC

Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016 – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Study: GBS symptoms more severe when caused by Zika – CIDRAP (free)

 


Randomized Trial: Five-Year Outcomes with PCI Guided by FFR

23 May, 2018 | 12:27h | UTC

Five-Year Outcomes with PCI Guided by Fractional Flow Reserve – New England Journal of Medicine (free)

Commentary: FFR in PCI for Stable CAD: Lasting Benefit Shown by FAME 2, SCAAR Data – TCTMD (free)

 


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