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Daily Archives: January 24, 2023

WHO | Five billion people unprotected from trans-fat leading to heart disease

24 Jan, 2023 | 14:44h | UTC

News Release: Five billion people unprotected from trans fat leading to heart disease – World Health Organization

Report: Countdown to 2023: WHO report on global trans-fat elimination 2022 – World Health Organization

Commentary: Five Billion People Exposed to Industrially Produced Trans Fats – Health Policy Watch

Related:

Brazil and Peru join growing number of countries in the Americas that are eliminating industrially produced trans fats – Pan American Health Association / World Health Organization

WHO: More than 3 billion people protected from harmful trans-fat in their food

Action Package: WHO Plan to Eliminate Trans-fatty Acids from Global Food Supply

WHO Draft Guideline: Saturated Fatty Acid and Trans-fatty Intake for Adults and Children

Banning trans fats in New York prevented thousands of heart attacks

 


AHA Statement | Surgical management and mechanical circulatory support in high-risk pulmonary embolisms

24 Jan, 2023 | 14:40h | UTC

Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association – Journal of the American Heart Association

News Release: New statement suggests more patients may benefit from surgery for pulmonary embolism – American Heart Association

 

Commentary from one of the authors on Twitter (thread – click for more)

 


ACP Guideline | Nonpharmacologic and pharmacologic treatments of adults in the acute phase of major depressive disorder

24 Jan, 2023 | 14:41h | UTC

Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

See also:

Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians – Annals of Internal Medicine

Cost-Effectiveness of First- and Second-Step Treatment Strategies for Major Depressive Disorder: A Rapid Review – Annals of Internal Medicine

Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments: A Rapid Review – Annals of Internal Medicine

Annals Video Summary – Nonpharmacologic and Pharmacologic Treatments for Adult Patients With Major Depressive Disorder – Annals of Internal Medicine

 


RCT | Outcomes not different with early restrictive vs. liberal fluid management in sepsis-induced hypotension

24 Jan, 2023 | 14:38h | UTC

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Study comparing early interventions for sepsis shows patients have identical outcomes – Vanderbilt University Medical Center

 

Commentary on Twitter

 


SR | Medication review in hospitalized patients to reduce morbidity and mortality

24 Jan, 2023 | 14:37h | UTC

Medication review in hospitalised patients to reduce morbidity and mortality – Cochrane Library

Summary: What are the benefits and risks of medication reviews for hospitalized adults? – Cochrane Library

 

Commentary on Twitter (thread – click for more)

 


ChatGPT listed as author on research papers: many scientists disapprove

24 Jan, 2023 | 14:36h | UTC

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Related: Abstracts written by ChatGPT fool scientists

 


RCT | 2 days of postoperative antibiotics is noninferior to 5 days in patients with complex appendicitis

24 Jan, 2023 | 14:33h | UTC

2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary: Trial supports shorter postoperative antibiotics for complex appendicitis – CIDRAP

 

Commentary on Twitter

 


Perspective | The case of statins, diabetes, and bias in observational studies

24 Jan, 2023 | 14:35h | UTC

The Case of Statins, Diabetes, and Bias in Observational Studies – Sensible Medicine

 


FDA no longer needs to require animal tests before human drug trials

24 Jan, 2023 | 14:32h | UTC

FDA no longer needs to require animal tests before human drug trials – Science

See also: The FDA no longer requires all drugs to be tested on animals before human trials – NPR

 


Cohort Study | The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity

24 Jan, 2023 | 14:31h | UTC

The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity: a UK primary care cohort study of disease burden over 10 years – The Lancet Psychiatry

Commentary: Severe mental illness and comorbid chronic physical illness: the clock’s ticking – The Mental Elf

 

Commentary on Twitter

 


2023 ACC expert consensus decision pathway on comprehensive multidisciplinary care for the patient with cardiac amyloidosis

24 Jan, 2023 | 14:29h | UTC

2023 ACC Expert Consensus Decision Pathway on Comprehensive Multidisciplinary Care for the Patient With Cardiac Amyloidosis: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Key Points: 2023 ACC Expert Consensus on Cardiac Amyloidosis – American College of Cardiology

News Release: ACC Expert Consensus Decision Pathway Focuses on Diagnosis and Management of Cardiac Amyloidosis – American College of Cardiology

 

Commentary on Twitter

 


ASCO Guideline | Management of fever and neutropenia in pediatric patients with cancer and hematopoietic cell transplantation recipients

24 Jan, 2023 | 14:28h | UTC

Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update – Journal of Clinical Oncology

 


RCT | Low-dose exercise provides similar benefits as high-dose exercise in patients with knee osteoarthritis

24 Jan, 2023 | 14:26h | UTC

High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis: A Randomized Controlled Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Low- vs High-Dose Exercise Programs Yielded Similar Benefits in Patients with Knee Osteoarthritis – HCP Live

 


Review | Common sleep disorders in children

24 Jan, 2023 | 14:22h | UTC

Common Sleep Disorders in Children – American Family Physician

Note: AFP provides superb review articles that are freely available one year after publication.

 


M-A | Assessing the diagnostic performance of new commercial IGRAs for Mycobacterium tuberculosis infection

24 Jan, 2023 | 14:25h | UTC

Assessing the diagnostic performance of new commercial IGRAs for Mycobacterium tuberculosis infection: a systematic review and meta-analysis – Clinical Infectious Diseases

 

Commentary on Twitter

 


M-A | Diagnostic value of four biomarkers in detecting neonatal sepsis in low- and middle-income countries

24 Jan, 2023 | 14:21h | UTC

Systematic review and meta-analysis of the diagnostic value of four biomarkers in detecting neonatal sepsis in low- and middle-income countries – BMJ Paediatrics Open

 


M-A | Metabolic side effects in persons with schizophrenia during mid- to long-term treatment with antipsychotics

24 Jan, 2023 | 14:23h | UTC

Metabolic side effects in persons with schizophrenia during mid- to long-term treatment with antipsychotics: a network meta-analysis of randomized controlled trials – World Psychiatry

Commentary: Metabolic Side Effects of Antipsychotics Vary, Meta-Analysis Finds – Psychiatric News Alert

 


Single-arm phase 2 study | Neoadjuvant pembrolizumab in localized microsatellite instability high/deficient mismatch repair solid tumors

24 Jan, 2023 | 14:19h | UTC

Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors – Journal of Clinical Oncology (link to abstract – $ for full-text)

Editorial: Immunotherapy in Localized Microsatellite Instability–High/Mismatch Repair Deficient Solid Tumors: Are We Ready for a New Standard of Care? – Journal of Clinical Oncology

Commentary: Neoadjuvant Pembrolizumab in Localized MSI-H/dMMR Solid Tumors – The ASCO Post

 


M-A | Incidence of acute kidney injury in hospitalized children

24 Jan, 2023 | 14:18h | UTC

Incidence of Acute Kidney Injury in Hospitalized Children: A Meta-analysis – Pediatrics

 


RCT | Intracorporeal vs. extracorporeal anastomosis in robotic right colectomy

24 Jan, 2023 | 14:17h | UTC

Intracorporeal Versus Extracorporeal Anastomosis in Robotic Right Colectomy: A Multicenter, Triple-blind, Randomized Clinical Trial – Annals of Surgery (link to abstract – $ for full-text)

 


Cohort Study | Biomarker trends, incidence, and outcomes of immune checkpoint inhibitor–induced myocarditis

24 Jan, 2023 | 14:16h | UTC

Biomarker Trends, Incidence, and Outcomes of Immune Checkpoint Inhibitor–Induced Myocarditis – JACC: CardioOncology

Editorial: Biomarkers for Immune Checkpoint Inhibitor–Induced Myocarditis: Caution Needed – JACC: CardioOncology

News Release: New biomarker strategy devised to screen for, diagnose deadly heart complication from cancer treatment – University of Michigan

Commentary: Biomarker Trends of Immune Checkpoint Inhibitor–Induced Myocarditis – American College of Cardiology

 

Commentary from the author on Twitter

 


Cohort Study | Alcohol abstinence improves prognosis across all stages of portal hypertension in alcohol-related cirrhosis

24 Jan, 2023 | 14:14h | UTC

Alcohol abstinence improves prognosis across all stages of portal hypertension in alcohol-related cirrhosis – Clinical Gastroenterology and Hepatology

News Release: Scientists provide evidence of the positive effects of alcohol abstinence in advanced liver cirrhosis – University of Viena / News Medical

 


RCT | Breast-cancer–related lymphedema after reverse lymphatic mapping and selective axillary dissection vs. standard surgical treatment of axilla

24 Jan, 2023 | 14:15h | UTC

Occurrence of breast-cancer–related lymphedema after reverse lymphatic mapping and selective axillary dissection versus standard surgical treatment of axilla: A two-arm randomized clinical trial – Cancer

 

Commentary on Twitter

 


RCT | Effect of a multicomponent intervention delivered on a web-based platform on hypertension control

24 Jan, 2023 | 14:12h | UTC

Effect of a Multicomponent Intervention Delivered on a Web-Based Platform on Hypertension Control: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


Retrospective Study | Serial troponin-T and long-term outcomes in suspected acute coronary syndrome

24 Jan, 2023 | 14:09h | UTC

Serial troponin-T and long-term outcomes in suspected acute coronary syndrome – European Heart Journal

 

Commentary on Twitter

 


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