Daily Archives: September 1, 2022
AHA Scientific Statement | Management of infective endocarditis in people who inject drugs.
1 Sep, 2022 | 12:00h | UTCNews Release: Addiction management is key to treating heart infection in people who inject drugs – American Heart Association
Top Things to Know: Infective Endocarditis in People Who Inject Drugs – American Heart Association
Video: Management of Infective Endocarditis in People who Inject Drugs – American Heart Association
Commentaries:
AHA Addresses Infective Endocarditis in Injection Drug Users – HealthDay
Related: Management of Infective Endocarditis in People Who Inject Drugs – American College of Cardiology (the original article is paywalled but has an informative infographic)
Review | Covid-19 vaccines — immunity, variants, boosters.
1 Sep, 2022 | 11:57h | UTCCovid-19 Vaccines — Immunity, Variants, Boosters – New England Journal of Medicine
After the genome—a brief history of proteomics.
1 Sep, 2022 | 11:58h | UTCAfter the Genome—A Brief History of Proteomics – JAMA (free for a limited period)
Video: Proteomics 101 – JAMA
Commentary on Twitter
With researchers touting recent success in sequencing the #humangenome’s remaining gaps, an emerging frontier is #proteomics: identifying and studying an entire set of expressed #proteins in the human body and other organisms. https://t.co/KIhBbWiYpx #proteomes #proteoforms
— JAMA (@JAMA_current) August 31, 2022
Risk of BA.5 infection among persons exposed to previous SARS-CoV-2 variants.
1 Sep, 2022 | 11:56h | UTC
Commentary on Twitter
Conventional wisdom is that previous infection with omicron subvariant BA.1 or BA.2 does notprotect against BA.5, but data from Portugal show considerable protection against BA.5 infection from previous BA.1 or BA.2 infection. https://t.co/1qXPAENSyn pic.twitter.com/qKpbuF2DDu
— NEJM (@NEJM) August 31, 2022
Cohort Study | Dolutegravir in pregnancy as compared with current HIV regimens.
1 Sep, 2022 | 11:55h | UTCDolutegravir in Pregnancy as Compared with Current HIV Regimens in the United States – New England Journal of Medicine (link to abstract – $ for full-text)
Related:
RCT | 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy.
WHO Recommends Dolutegravir as Preferred HIV Treatment Option in All Populations
RCT: Dolutegravir or Darunavir in combination with Zidovudine or Tenofovir to treat HIV.
Commentary on Twitter
In this study involving 1257 pregnancies among persons treated for HIV-1 infection during pregnancy, dolutegravir was better at suppressing viral loads than other regimens, without evident safety concerns. https://t.co/CnShoao995 pic.twitter.com/Qne24I1482
— NEJM (@NEJM) August 31, 2022
Reports of asymptomatic monkeypox suggest that, at the very least, some infections go unnoticed.
1 Sep, 2022 | 11:54h | UTC
Guideline | Patient preparation and radiation protection guidance for adult patients undergoing radioiodine treatment for thyroid cancer.
1 Sep, 2022 | 11:53h | UTC
RCT | Driving pressure-guided ventilation and postoperative pulmonary complications in thoracic surgery.
1 Sep, 2022 | 11:52h | UTC
RCT | Placement of an intrauterine device within 48 hours after early medical abortion.
1 Sep, 2022 | 11:51h | UTC
Cohort Study | Women have a lower incidence of ventricular fibrillation compared to men after an acute myocardial infarction.
1 Sep, 2022 | 11:49h | UTC
RCT | In patients with rheumatoid arthritis, Tofacitinib is associated with increased risk of infections compared to TNF inhibitors.
1 Sep, 2022 | 11:50h | UTC
Commentary on Twitter
Check out our latest paper on infections in #rheumatoid #arthritis patients from the ORAL Surveillance trial:
▶️ tofacitinib lead to higher infection rates (serious and non-serious) vs TNFi
▶️ increased rates more pronounced in patients aged > 65🔗 https://t.co/3pVrnzzFWD pic.twitter.com/Kf7p6D0jBD
— Annals of the Rheumatic Diseases (@eular_ARD) August 11, 2022
Multicenter, international retrospective audit of lower extremity open fractures.
1 Sep, 2022 | 11:48h | UTC
Severity of Esophageal Anastomotic Leak in patients after esophagectomy: the SEAL score.
1 Sep, 2022 | 11:47h | UTC
Commentary on Twitter (thread – click for more)
1/3 This week our SEAL Score manuscript was published in @BJSurgery:https://t.co/MUNmaf7l6B
A major milestone for TENTACLE – Esophagus, and first step towards finding evidence for treatment of anastomotic leak. More to come!— TENTACLE study (@tentaclestudy) July 2, 2022
Single-arm phase 2 study | Neoadjuvant Nivolumab plus Ipilimumab and Adjuvant Nivolumab in localized deficient mismatch repair/microsatellite instability-high gastric or esophagogastric junction adenocarcinoma.
1 Sep, 2022 | 11:47h | UTC
Study Commentary | Zinc for the prevention or treatment of respiratory tract infections: a new systematic review.
1 Sep, 2022 | 11:46h | UTC
Meta-analysis of observational studies | Leisure activities and the risk of dementia.
1 Sep, 2022 | 11:44h | UTCLeisure Activities and the Risk of Dementia: A Systematic Review and Meta-Analysis – Neurology
News Release: Which Leisure Activities Are Linked to Lower Risk of Dementia? – American Academy of Neurology
Incorporating productivity loss in health economic evaluations: a review of guidelines and practices worldwide.
1 Sep, 2022 | 11:41h | UTC
Study shows dentists should give antibiotics to high-risk patients to help prevent infectious endocarditis.
1 Sep, 2022 | 11:43h | UTCOriginal Study: Antibiotic Prophylaxis Against Infective Endocarditis Before Invasive Dental Procedures – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: UK dentists should give antibiotics to patients at risk of heart infection – study – The Guardian
Characteristics and outcomes of anterior mediastinal cystic lesions diagnosed on chest MRI: implications for management of cystic lesions.
1 Sep, 2022 | 11:41h | UTC
Meta-analysis of randomized trials | Antibiotic therapy vs. appendicectomy for uncomplicated acute appendicitis.
1 Sep, 2022 | 11:40h | UTCRelated:
Review: Diagnosis of uncomplicated and complicated appendicitis in adults.
A Randomized trial comparing antibiotics with appendectomy for appendicitis
Commentary on Twitter
👼 The reborn of surgery for uncomplicated acute appendicitis ?!
🧐 RCT comparing antibiotic 🤜🤛 appendicectomy: meta analysis of > 3000 patients
💊 No benefit on complications and LOS
🏥 Antibiotics 6X increase in hospital readmission!
🆓 full text https://t.co/VhL9u0Weua pic.twitter.com/SdyK0rKS3f
— Giovanni Marchegiani (@Gio_Marchegiani) August 17, 2022
Why it’s not safe to shower during a thunderstorm.
1 Sep, 2022 | 11:38h | UTCWhy it’s not safe to shower during a thunderstorm – The Conversation
Perspective | Ensuring an accurate scientific record in an era of pre-print servers.
1 Sep, 2022 | 11:38h | UTC
RCT | The effect of a liberal approach to glucose control in critically ill patients with type 2 diabetes.
1 Sep, 2022 | 11:37h | UTCThe Effect of a Liberal Approach to Glucose Control in Critically Ill Patients with Type 2 Diabetes: A multicenter, parallel-group, open-label, randomized clinical trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentary from the author on Twitter
Excited to share results of the LUCID trial! A liberal approach to blood glucose targets reduced incidence hypoglycemia but did not improve patient-centered outcomes. https://t.co/HO53nzfBQT@MelbourneICU @CRENutrition @BellomoRinaldo @icurah @DogICUma @Eastwoodgm @MACHAustralia
— Alex Poole (@AlexPPoole) May 25, 2022
Systematic Review | The effect of heparin and its preparations on disseminated intravascular coagulation mortality and hospitalization.
1 Sep, 2022 | 11:34h | UTC
Systematic Review | Duplex ultrasound for diagnosing symptomatic carotid stenosis in the extracranial segments.
1 Sep, 2022 | 11:36h | UTC