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Daily Archives: February 10, 2022

RCT: In patients 60 years of age or older with an intracapsular hip fracture, cemented hemiarthroplasty resulted in better quality of life and lower risk of periprosthetic fracture than uncemented hemiarthroplasty.

10 Feb, 2022 | 10:19h | UTC

Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture – New England Journal of Medicine

 

Commentary on Twitter

 


M-A: The prevalence of loneliness across 113 countries.

10 Feb, 2022 | 10:08h | UTC

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Editorial: We need a public health approach to loneliness

News Release: Problematic levels of loneliness widespread in many countries – BMJ

 

Commentary on Twitter

 


Clinical Review: Advances in the management of cardioembolic stroke associated with patent foramen ovale.

10 Feb, 2022 | 10:17h | UTC

Advances in the management of cardioembolic stroke associated with patent foramen ovale – The BMJ

Related:

Patent Foramen Ovale (PFO) After Stroke: Meta-analysis suggests the application of a multivariable causal classification system may better distinguish patient subgroups who may benefit from PFO closure from those unlikely to receive benefit.

Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases

Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology – Neurology

 


AHA Scientific Statement: Identifying best practices to improve evaluation and management of in-hospital stroke.

10 Feb, 2022 | 10:13h | UTC

Identifying Best Practices to Improve Evaluation and Management of In-Hospital Stroke: A Scientific Statement From the American Heart Association – Stroke

News Release: Five elements to optimize treatment of in-hospital stroke – American Heart Association

 

Commentary on Twitter

 


Sweden ends COVID-19 testing as pandemic restrictions lifted – “only health care and elderly care workers and the most vulnerable will be entitled to free PCR testing if they are symptomatic, while the rest of the population will simply be asked to stay home if they show symptoms that could be COVID-19”.

10 Feb, 2022 | 10:07h | UTC

Sweden ends COVID-19 testing as pandemic restrictions lifted – Associated Press

Related:

How Denmark Decided COVID Isn’t a Critical Threat to Society – “The country became the first in the EU to lift all COVID restrictions despite leading the world in per capita infections”.

Covid: Europe set for ‘long period of tranquillity’ in pandemic, says WHO.

As Denmark scraps COVID restrictions, WHO urges caution.

Despite the ongoing spread of Omicron, some European countries have decided to lift Covid-19 restrictions.

 


Clinical practice guideline on tympanostomy tubes in children.

10 Feb, 2022 | 10:10h | UTC

Executive Summary of Clinical Practice Guideline on Tympanostomy Tubes in Children (Update) – Otolaryngology–Head and Neck Surgery

 


A population-based study in Qatar showed previous infection provided robust protection against reinfection with the alpha, beta, and delta variants of SARS-CoV-2 (approximately 90%). However, protection against reinfection with the omicron variant was lower (around 60%).

10 Feb, 2022 | 10:04h | UTC

Protection against the Omicron Variant from Previous SARS-CoV-2 Infection – New England Journal of Medicine

 

Commentary on Twitter

 


RCT: Final analysis of efficacy and safety of single-dose J&J vaccine.

10 Feb, 2022 | 10:03h | UTC

Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S – New England Journal of Medicine

 

Commentary on Twitter

 


Vaccine effectiveness of heterologous CoronaVac plus Pfizer in Brazil.

10 Feb, 2022 | 10:01h | UTC

Vaccine effectiveness of heterologous CoronaVac plus BNT162b2 in Brazil – Nature Medicine

 

Commentary on Twitter

 


RCT: Subcutaneous Tirzepatide added to titrated Insulin Glargine improves glycemic control in patients with Type 2 Diabetes.

10 Feb, 2022 | 10:00h | UTC

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Tirzepatide for Patients With Type 2 Diabetes – JAMA

Commentary: SURPASS-5 Data: Tirzepatide Plus Insulin Glargine Improve Glycemic Control in T2D – AJMC

Related:

RCT: In patients with Type 2 Diabetes, Tirzepatide is associated with reduced weight, improved glycemic control, and lower risk of hypoglycemia compared to insulin glargine.

RCT: Once-weekly tirzepatide vs. once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes.

RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.

RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.

 


2021 Brazilian Thoracic Association recommendations for the management of severe asthma.

10 Feb, 2022 | 08:52h | UTC

2021 Brazilian Thoracic Association recommendations for the management of severe asthma – Jornal Brasileiro de Pneumologia

 


Position statement on the care of the athlete and athletic person with diabetes.

10 Feb, 2022 | 08:49h | UTC

American Medical Society for Sports Medicine Position Statement on the Care of the Athlete and Athletic Person With Diabetes – Clinical Journal of Sport Medicine

 


M-A: In patients with acute coronary syndrome undergoing percutaneous coronary intervention, short duration of dual antiplatelet therapy (DAPT) was comparable to de-escalation regarding all-cause death. De-escalation reduced the risk for adverse cardiovascular events, while short DAPT decreased major bleeding.

10 Feb, 2022 | 08:46h | UTC

Short Duration of DAPT Versus De-Escalation After Percutaneous Coronary Intervention for Acute Coronary Syndromes – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: Short Duration of DAPT vs. De-Escalation After PCI for ACS – American College of Cardiology

 


GOLD Report 2022: Global strategy for prevention, diagnosis and management of COPD.

10 Feb, 2022 | 08:53h | UTC

GOLD Report 2022: Global strategy for prevention, diagnosis and management of COPD

 


Systematic Review: Overuse of diagnostic testing in healthcare.

10 Feb, 2022 | 08:47h | UTC

Overuse of diagnostic testing in healthcare: a systematic review – BMJ Quality & Safety

 


Culprit medications and risk factors associated with Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A population-based nested case–control study.

10 Feb, 2022 | 08:42h | UTC

Culprit Medications and Risk Factors Associated with Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Population-Based Nested Case–Control Study – American Journal of Clinical Dermatology

 


M-A: Time to benefit for stroke reduction after blood pressure treatment in older adults.

10 Feb, 2022 | 08:44h | UTC

Time to benefit for stroke reduction after blood pressure treatment in older adults: A meta-analysis – Journal of the American Geriatrics Society

News Release: New research finds more intensive blood pressure treatment may prevent strokes in older adults – Wiley

 


Primer for artificial intelligence in primary care.

10 Feb, 2022 | 08:36h | UTC

Primer for artificial intelligence in primary care – Canadian Family Physician

Editorial: Artificial intelligence and the family physician

 


Medication management for heart failure with reduced ejection fraction: Clinical pearls for optimizing evidenced-informed therapy.

10 Feb, 2022 | 08:41h | UTC

Medication management for heart failure with reduced ejection fraction – Canadian Family Physician

 


Guide to writing and publishing a scientific manuscript: Part 1—The structure.

10 Feb, 2022 | 08:35h | UTC

Guide to writing and publishing a scientific manuscript: Part 1—The structure – Canadian Journal of Emergency Medicine

 


Short Review: Biologics for episodic and chronic migraines.

10 Feb, 2022 | 08:40h | UTC

Biologics for episodic and chronic migraines – Canadian Family Physician

 


Perioperative approach to precapillary pulmonary hypertension in non-cardiac non-obstetric surgery.

10 Feb, 2022 | 08:34h | UTC

Perioperative approach to precapillary pulmonary hypertension in non-cardiac non-obstetric surgery – European Respiratory Review

 


Review: Cognitive-behavioural therapy for children with irritable bowel syndrome.

10 Feb, 2022 | 08:38h | UTC

Cognitive-behavioural therapy for children with irritable bowel syndrome – Canadian Family Physician

 


Abemaciclib with endocrine therapy in the treatment of high-risk early breast cancer: ASCO optimal adjuvant chemotherapy and targeted therapy guideline rapid recommendation update.

10 Feb, 2022 | 08:33h | UTC

Abemaciclib With Endocrine Therapy in the Treatment of High-Risk Early Breast Cancer: ASCO Optimal Adjuvant Chemotherapy and Targeted Therapy Guideline Rapid Recommendation Update – Journal of Clinical Oncology

 


Interstitial pneumonia with autoimmune features: challenges and controversies.

10 Feb, 2022 | 08:33h | UTC

Interstitial pneumonia with autoimmune features: challenges and controversies – European Respiratory Review

 


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