Daily Archives: February 9, 2022 | LinksMedicus Free Medical News & Perspectives

Opinion: Development of clinical practice guidelines ‘is a mess’.

9 Feb, 2022 | 10:16h | UTC

Development of clinical practice guidelines ‘is a mess’ – STAT

IDSA Updated Covid-19 Guideline now supports the use of convalescent plasma in ambulatory patients with mild to moderate COVID-19 at high risk for progression to severe disease.

9 Feb, 2022 | 10:15h | UTC

IDSA Guidelines on the Treatment and Management of Patients with COVID-19 – Infectious Diseases Society of America

Commentary on Twitter

Update Alert: Revised recommendation on the use of #convalescentplasma in ambulatory patients w/ COVID-19 at high risk of progression to severe disease w/ no other treatment options.

📄: https://t.co/YRCxtdilXT #COVID19Guidelines @JGPharmD @adarsh_bhimraj @RMKGandhi @ShohamTxID pic.twitter.com/KpXnywH362

— IDSA (@IDSAInfo) February 8, 2022

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

9 Feb, 2022 | 10:18h | UTC

European Society of clinical microbiology and infectious diseases (ESCMID) guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli (endorsed by ESICM –European Society of intensive care Medicine) – Clinical Microbiology and Infection

WHO: Two years into COVID pandemic, most countries still face significant health service disruptions.

9 Feb, 2022 | 10:13h | UTC

Two Years into COVID Pandemic, Most Countries Still Face Significant Health Service Disruptions – Health Policy Watch

Original Report: Third round of the global pulse survey on continuity of essential health services during the COVID-19 pandemic – World Health Organization

Cohort Study: Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England.

9 Feb, 2022 | 10:12h | UTC

Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study – The Lancet Child & Adolescent Health

Editorial: Assessing the impact of the pandemic in children and adolescents: SARS-CoV-2 infection and beyond – The Lancet Child & Adolescent Health

Commentary: Long COVID and kids: more research is urgently needed – Nature

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

E ditorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Commentary on Twitter (thread – click for more)

NEW RESEARCH: free! Two studies on adolescent #LongCovid. Both found high symptom burden in COVID positive and negative participants; very heterogenous symptom profile. Pandemic has had profound impact on all adolescents. https://t.co/YzU3ogXZrw pic.twitter.com/ina0DgPxBf

— The Lancet Child & Adolescent Health (@LancetChildAdol) February 8, 2022

Though rare, Moderna Covid vaccine recipients have higher risk of heart inflammation than Pfizer.

9 Feb, 2022 | 10:06h | UTC

Though rare, Moderna Covid vaccine recipients have higher risk of heart inflammation than Pfizer – CNBC

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

9 Feb, 2022 | 10:08h | UTC

Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy: a multi-database, self-controlled case series study -medRxiv

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

Commentary on Twitter

The incidence of mRNA vaccine myocarditis or pericarditis in Italy in ~3 million vaccinees age 12-39. Excess cases per 100,000; orange is 2nd dose, blue 1st dose. https://t.co/xvdV4qSdHw
Pfizer:~1/100,000 age 12-39, all 2nd dose
Moderna,: >5/100,000, age 12-39, and some 1st dose pic.twitter.com/Y1jfGrU53v

— Eric Topol (@EricTopol) February 9, 2022

Australasian Consensus Guidelines for the use of antifungal agents in the hematology-oncology setting.

9 Feb, 2022 | 08:49h | UTC

Introduction to the updated Australasian consensus guidelines for the management of invasive fungal disease and use of antifungal agents in the haematology/oncology setting, 2021

Consensus guidelines for antifungal stewardship, surveillance and infection prevention, 2021

Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy and haemopoietic stem cell transplant recipients, 2021

Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2021

Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021

Consensus guidelines for the diagnosis and management of cryptococcosis and rare yeast infections in the haematology/oncology setting, 2021

Consensus guidelines for the diagnosis and management of invasive aspergillosis, 2021

Consensus guidelines for the diagnosis and management of invasive fungal disease due to moulds other than Aspergillus in the haematology/oncology setting, 2021

Consensus guidelines for improving patients’ understanding of invasive fungal disease and related risk prevention in the haematology/oncology setting, 2021

Study suggests routine cardiac screening is not needed before return to play in junior competitive athletes with mild or asymptomatic SARS-CoV-2.

9 Feb, 2022 | 10:01h | UTC

SARS-CoV-2 infection and return to play in junior competitive athletes: is systematic cardiac screening needed? – British Journal of Sports Medicine

Perspective | Tracking COVID-19 infections: time for change.

9 Feb, 2022 | 10:03h | UTC

Tracking COVID-19 infections: time for change – Nature

German Guidelines for Teledermatology.

9 Feb, 2022 | 08:47h | UTC

S2k-Guideline for Teledermatology – Journal of the German Society of Dermatology

Systematic Review: Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations.

9 Feb, 2022 | 10:02h | UTC

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review – Clinical Microbiology and Infection

The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022.

9 Feb, 2022 | 08:46h | UTC

The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022 – American Journal of Kidney Diseases

Expert Consensus: Treatment algorithm in cancer-associated thrombosis.

9 Feb, 2022 | 08:42h | UTC

Treatment Algorithm in Cancer-Associated Thrombosis: Updated Canadian Expert Consensus – Current Oncology

Randomized trial suggests it is safe to withhold antimicrobial prophylaxis in patients undergoing transurethral resection of the prostate without preoperative pyuria or preoperative indwelling catheter.

9 Feb, 2022 | 08:41h | UTC

Antimicrobial Prophylaxis in Transurethral Resection of the Prostate: Results of a Randomized Trial – The Journal of Urology (link to abstract – $ for full-text)

British guidelines for the management of HIV-2.

9 Feb, 2022 | 08:43h | UTC

British HIV Association guidelines for the management of HIV-2 2021 – HIV Medicine

Review: Supraventricular arrhythmia in pregnancy.

9 Feb, 2022 | 08:38h | UTC

Supraventricular arrhythmia in pregnancy – Heart

Systematic Review: Video-observed therapy vs. directly observed therapy in patients with tuberculosis.

9 Feb, 2022 | 08:35h | UTC

Video-Observed Therapy Versus Directly Observed Therapy in Patients With Tuberculosis – American Journal of Preventive Medicine (link to abstract – $ for full-text)

Commentary on Twitter

Our latest publication on @AmJPrevMed : Video-Observed Therapy Versus Directly Observed Therapy in Patients With Tuberculosis. Implementation of VOT improved medication adherence and bacteriological resolution compared with that of DOT in TB patients.https://t.co/xcWzrxLbHB? pic.twitter.com/4ldYJ2umd7

— Bang Truong (@bangphd_epi) December 13, 2021

M-A: Efficacy and safety of first-line systemic therapy for metastatic renal cell carcinoma.

9 Feb, 2022 | 08:39h | UTC

Efficacy and Safety of First-line Systemic Therapy for Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-analysis – European Urology Open Science

Podcast: Constipation Pearls.

9 Feb, 2022 | 08:37h | UTC

#314 When the Flow Won’t Go: Constipation with Dr. Iris Wang – The Curbsiders

Systematic Review: Magnetic resonance imaging for diagnosis of acute appendicitis.

9 Feb, 2022 | 08:32h | UTC

Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis – Cochrane Library

Summary: Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis – Cochrane Library

Commentary on Twitter

#Appendicitis is a common condition that is usually treated w emergency surgery, but can be difficult to diagnose. Can Tools MRI can help diagnose quickly & early? https://t.co/hsolsjB3A8 New systematic review looks at evidence from 58 studies. @mrnigeldsouza

— The Cochrane Library (@CochraneLibrary) December 22, 2021