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Daily Archives: November 17, 2021

Case-control study: sleep disorders linked to more severe outcomes from COVID-19, study suggests.

17 Nov, 2021 | 08:50h | UTC

News Release: Sleep disorders linked with more severe outcomes from COVID-19, study suggests – Cleveland Clinic

Original Study: Association of Sleep-Related Hypoxia With Risk of COVID-19 Hospitalizations and Mortality in a Large Integrated Health System – JAMA Network Open

Commentary: Some sleep disorders may lead to worse COVID-19 outcomes – CIDRAP

 

Commentary on Twitter

 

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic.

17 Nov, 2021 | 08:56h | UTC

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic – European Heart Journal

Part 1—epidemiology, pathophysiology, and diagnosis

Part 2—care pathways, treatment, and follow-up

News release: European Society of Cardiology COVID-19 guidance launched – European Society of Cardiology

 

Commentaries on Twitter

 

Observational study found monitoring outpatients with Covid-19 using text messages that allowed the report of worsening symptoms was associated with improved outcomes.

17 Nov, 2021 | 08:53h | UTC

Comparative Effectiveness of an Automated Text Messaging Service for Monitoring COVID-19 at Home – Annals of Internal Medicine

News Release: Automated Texting System Saved Lives Weekly During First COVID Surge – Penn Medicine

Commentaries:

Monitoring outpatients by text appeared to reduce mortality from COVID-19 – ACP Internist

Texting saved lives during Covid. What does that mean for health care’s future? – STAT

 

Commentary from the author on Twitter (thread – click for more)

 

The big questions about Covid-19 booster shots – “From the why to the who, we still need a lot of answers about booster shots”.

17 Nov, 2021 | 08:48h | UTC

The big questions about Covid-19 booster shots – Vox

 

Commentary on Twitter

 

Pfizer COVID Pill to Be Made, Sold Cheaply in 95 Poor Countries.

17 Nov, 2021 | 08:40h | UTC

Pfizer COVID Pill to Be Made, Sold Cheaply in 95 Poor Countries – HealthDay

See also:

Pfizer agrees to license generic versions of its COVID-19 pill — in some countries – NPR

Pfizer and Medicines Patent Pool Reach ‘Ground-breaking’ Voluntary Licensing Deal for New COVID-19 Treatment Pill – Health Policy Watch

Pfizer Will Allow Its Covid Pill to Be Made and Sold Cheaply in Poor Countries – The New York Times (a few articles per month are free)

 

AAN Guideline: Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease.

17 Nov, 2021 | 08:32h | UTC

Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease Practice Guideline Summary – Neurology

News Release: AAN Issues Guideline for Treatment of Early Parkinson’s Disease – American Academy of Neurology

 

MSF responds to Pfizer and Medicines Patent Pool license for new Covid-19 treatment – “The deal, however, only covers 53 percent of the world’s population and excludes people in several upper-middle-income countries, leaving this promising medicine out of reach for millions”.

17 Nov, 2021 | 08:38h | UTC

MSF responds to Pfizer and Medicines Patent Pool license for new Covid-19 treatment – Médecins Sans Frontières

 

Commentary on Twitter

 

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.

17 Nov, 2021 | 08:42h | UTC

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians – The Journal of the American Board of Family Medicine

Related:

Global surveillance, research, and collaboration needed to improve understanding and management of long COVID.

Provocative study suggests that persistent physical symptoms after COVID-19 infection may be associated more with the belief in having been infected with SARS-CoV-2 than with having laboratory-confirmed COVID-19 infection.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)

 

Individual participant data meta-analysis of major randomized trials showed that treatment of hypertension with ACEIs or ARBs reduced the risk of new-onset type 2 diabetes compared to other drugs.

17 Nov, 2021 | 08:29h | UTC

Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis – The Lancet

Commentaries:

Expert reaction to an individual participant data meta-analysis on blood pressure lowering and risk of onset of type-2 diabetes – Science Media Centre

Blood pressure drugs could prevent type 2 diabetes, study finds – The Guardian

 

Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.

17 Nov, 2021 | 08:33h | UTC

Preoperative Care for Cataract Surgery: The Society for Ambulatory Anesthesia Position Statement – Anesthesia & Analgesia

 

Commentary on Twitter

 

Randomized, crossover clinical trial: In patients with heart failure with preserved ejection fraction and chronotropic incompetence, betablocker withdrawal improved maximal functional capacity.

17 Nov, 2021 | 08:27h | UTC

Effect of β-Blocker Withdrawal on Functional Capacity in Heart Failure and Preserved Ejection Fraction – Journal of the American College of Cardiology

Commentary: Peak VO2 Improved After Beta-Blocker Withdrawal in Some HFpEF Patients: Beta-blockers may not benefit HFpEF patients with chronotropic incompetence – MedPage Today (free registration required)

 

Nursing care for oncologic patients undergoing surgery using an enhanced recovery approach.

17 Nov, 2021 | 08:22h | UTC

Oncologic Surgical Care Using an Enhanced Recovery Approach – AACN Advanced Critical Care

News release: Enhanced Recovery Approach Changes Care for Surgical Oncology Patients – American Association of Critical-Care Nurses

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

 

Phase 2 RCT: Once-weekly cagrilintide is effective for weight management in people with overweight and obesity.

17 Nov, 2021 | 08:23h | UTC

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial – The Lancet (link to abstract – $ for full-text)

 

RCT: Adjustable intragastric balloon resulted in significant weight loss at 32 weeks, but intolerance caused early removal of the device in 17% of patients, and device-related serious adverse events were observed in 4% of patients.

17 Nov, 2021 | 08:26h | UTC

Adjustable intragastric balloon for treatment of obesity: a multicentre, open-label, randomised clinical trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.

17 Nov, 2021 | 08:19h | UTC

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps – Nature Medicine

 

Commentary on Twitter

 

Long-term follow up of randomized trials found that children who were given nutrient or supplement enriched formula milk as babies didn’t have higher academic performances as adolescents.

17 Nov, 2021 | 08:14h | UTC

News release: Study finds no benefit of enriched formula milks on later academic performance – British Medical Journal

Original Study: Effect of nutritionally modified infant formula on academic performance: linkage of seven dormant randomised controlled trials to national education data – The BMJ

Editorial: Enriched formula milks and academic performance in later childhood – The BMJ

 

Commentary on Twitter

 

A billion-dollar donation: estimating the cost of researchers’ time spent on peer review.

17 Nov, 2021 | 08:16h | UTC

A billion-dollar donation: estimating the cost of researchers’ time spent on peer review – Research Integrity and Peer Review

Related:

M-A: Effects of experimental interventions to improve the peer‐review process – “Modifications of the traditional peer‐review process at reviewer‐level are associated with improved quality, at the price of longer duration.”

The $450 question: Should journals pay peer reviewers?

Opinion: Peer reviewers—time for mass rebellion?

5 things we learned about peer review in 2020

Editorial: Evaluation and Peer Review During a Pandemic

 

Commentary on Twitter

 

Real-world ethics in palliative care: A systematic review of the ethical challenges reported by specialist palliative care practitioners in their clinical practice.

17 Nov, 2021 | 08:18h | UTC

Real-world ethics in palliative care: A systematic review of the ethical challenges reported by specialist palliative care practitioners in their clinical practice – Palliative Medicine

 

Commentary on Twitter

 

Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomized controlled trials.

17 Nov, 2021 | 08:12h | UTC

Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials – PLOS Medicine

 

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