Daily Archives: April 14, 2021
RCT: Low-dose aspirin safely suppresses the recurrence of colorectal polyps in patients with familial adenomatous polyposis
14 Apr, 2021 | 01:49h | UTCChemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Ishikawa et al – Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a randomised, 2×2 factorial trialhttps://t.co/NJ4b77p591#gitwitter #FAP #crcsm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) April 2, 2021
USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening
14 Apr, 2021 | 01:47h | UTCVitamin D Deficiency in Adults: Screening – U.S. Preventive Services Task Force
Evidence Report: Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Editorial: The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues – JAMA AND Why USPSTF Still Finds Insufficient Evidence to Support Screening for Vitamin D Deficiency – JAMA Network Open
JAMA Patient Page: Screening for Vitamin D Deficiency in Adults
Study shows practitioners overestimate the probability of disease before and after testing
14 Apr, 2021 | 01:44h | UTCAccuracy of Practitioner Estimates of Probability of Diagnosis Before and After Testing – JAMA Internal Medicine (free for a limited period)
Commentary: Physicians, Probabilities, and Populations—Estimating the Likelihood of Disease for Common Clinical Scenarios – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
How good are doctors at diagnosis?
This is the most relevant paper I have written. Not perfect but addresses a huge issue I think could change medicine if acknowledged
…it has changed how I think about diagnosishttps://t.co/4ZtoD3F4rF @JAMAInternalMed @drjohnm
1/n— Dan Morgan (@dr_dmorgan) April 12, 2021
M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain
14 Apr, 2021 | 01:39h | UTC
Commentary on Twitter
Just published in BJSM ???
Effectiveness of treatments for acute and subacute mechanical non-specific low back pain: a systematic review with network meta-analysis
?????https://t.co/bx06RPLTbT pic.twitter.com/RzHkwN2nTp
— Physio Meets Science (@PhysioMeScience) April 13, 2021
New studies suggest SARS-CoV-2 variant B.1.1.7 is not more deadly, just more transmissible
14 Apr, 2021 | 02:12h | UTCCommentaries: Expert reaction to two papers looking at the transmissibility and severity of the B.1.1.7 variant – Science Media Centre AND UK coronavirus variant not more deadly, just spreads more easily, studies find – LiveScience
ESC Position Statement: Management of secondary mitral regurgitation in patients with heart failure
14 Apr, 2021 | 01:34h | UTC
Commentary on Twitter
Position statement on the management of secondary mitral regurgitation in patients with #HeartFailure (#HFA_ESC, #EACVI, #EHRA_ESC, #EAPCI) https://t.co/gZ8WtQu6vG @escardio #EHJ #ESCYoung @ehj_ed @rladeiraslopes pic.twitter.com/QKaFnbTVT0
— European Society of Cardiology Journals (@ESC_Journals) March 24, 2021
Viewpoint | Industry-Sponsored Speaker Programs—End of the Line?
14 Apr, 2021 | 01:36h | UTCIndustry-Sponsored Speaker Programs—End of the Line? – JAMA
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
14 Apr, 2021 | 01:27h | UTC
Diagnosis and management of leukocytoclastic vasculitis
14 Apr, 2021 | 01:26h | UTCDiagnosis and management of leukocytoclastic vasculitis – Internal and Emergency Medicine
Why would a Covid vaccine cause rare blood clots? Researchers have found clues
14 Apr, 2021 | 02:14h | UTCWhy would a Covid vaccine cause rare blood clots? Researchers have found clues – STAT
Related: How could a COVID vaccine cause blood clots? Scientists race to investigate – Nature
U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots
14 Apr, 2021 | 02:16h | UTCJoint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine – U.S. Food & Drug Administration
Commentaries: Covid-19: US suspends Johnson and Johnson vaccine rollout over blood clots – BMJ AND CDC and FDA recommend US pause use of Johnson & Johnson’s Covid-19 vaccine over blood clot concerns – CNN AND US halts J&J COVID vaccine after reports of blood clots – CIDRAP AND U.S. urges pause on use of Johnson & Johnson Covid-19 vaccine after rare blood clotting cases – CIDRAP
Long-term mortality of elderly patients after intensive care unit admission for COVID-19
14 Apr, 2021 | 02:09h | UTC
Commentary on Twitter
Long-term outcome of elderly (≥ 80y) #COVID19 pts admitted to #ICU: 6-month mortality ➡️ 72% (likely underestimated) at upper end of recent literature on older critical pts. Data supporting more informed goals-of-care decisions for this #SARSCoV2 cohort?https://t.co/mIKNxNpdC8 pic.twitter.com/OQS5SN5FXR
— Intens Care Med (@yourICM) April 13, 2021
WHO, agencies urge countries to suspend sale of live wild mammals at markets
14 Apr, 2021 | 02:06h | UTCWHO, agencies urge countries to suspend sale of live wild mammals at markets – Reuters
Original Guidance: Reducing public health risks associated with the sale of live wild animals of mammalian species in traditional food markets – World Health Organization
Review: Vaccine development for emerging infectious diseases
14 Apr, 2021 | 02:01h | UTCVaccine development for emerging infectious diseases – Nature
Opinion | Coronavirus Variants Don’t Have to Be Scary. Still, Mask Up.
14 Apr, 2021 | 02:05h | UTCCoronavirus Variants Don’t Have to Be Scary. Still, Mask Up. – The New York Times
Commentary on Twitter
"Viruses undergo mutations frequently, both within infected people and as they travel from one person to another," @EricTopol writes. "That’s why it’s important to remember this (modified) adage: All variants are innocent until proven guilty." https://t.co/Ju60zb5gST
— New York Times Opinion (@nytopinion) April 13, 2021
Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19
14 Apr, 2021 | 01:59h | UTCCommentary: CDC: 1 in 3 children hospitalized with COVID-19 requires treatment in ICU – UPI AND 12% of Children with COVID Are Hospitalized: Study – WebMD
Commentary on Twitter
Of 2430 pediatric patients who were hospitalized with COVID-19, 756 (31.1%) experienced severe COVID-19. Severe disease was more common in patients with chronic conditions, in male patients, and in children aged 2-11 years vs children aged 12-18 years. https://t.co/3fmlCFsmo8
— COVID Reference (@CovidReference) April 10, 2021