Daily Archives: March 2, 2021
Another study shows higher antibody titer responses to a single dose of mRNA vaccine among patients with previous COVID-19 infection
2 Mar, 2021 | 02:13h | UTCRelated: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary)
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
2 Mar, 2021 | 02:15h | UTC
Commentary on Twitter
Wonderful guidance from @WHO on ventilation. Here are a couple of pages for non-residential settings. All the things we've been talking about: minimum 10 L/s/person, open doors & windows for cross-ventilation, use exhaust fans, filtration. https://t.co/umMzhiqKza pic.twitter.com/UEZLahi87v
— Linsey Marr (@linseymarr) March 1, 2021
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
2 Mar, 2021 | 02:11h | UTCAcute covid-19 and multisystem inflammatory syndrome in children – The BMJ
Commentary on Twitter
The most common symptoms in children with acute SARS-CoV-2 infection are fever and cough. This Clinical Update looks at the presentation of SARS-CoV-2 infection in children, transmission dynamics, and multisystem inflammatory disease @asicksamuelshttps://t.co/XrDtAhJUb9
— The BMJ (@bmj_latest) March 1, 2021
Studies: Secondary infections in patients with severe COVID-19
2 Mar, 2021 | 02:05h | UTCSecondary Infections in Patients with Severe COVID-19 – NEJM Journal Watch
Scaling up COVID-19 rapid antigen tests: promises and challenges
2 Mar, 2021 | 02:09h | UTCScaling up COVID-19 rapid antigen tests: promises and challenges – The Lancet Infectious Diseases
Review: Cardiovascular biomarkers in patients with COVID-19
2 Mar, 2021 | 02:07h | UTC
Commentary on Twitter
Cardiovascular #biomarkers in patients with #COVID19 – review article by @escardio Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association #ACVC_ESC https://t.co/9Mcx24fX8y#EHJACVC #cardiotwitter #medtwitter pic.twitter.com/y7kD2Oylrj
— European Society of Cardiology Journals (@ESC_Journals) March 1, 2021
Serious bradycardia and Remdesivir for COVID-19: a new safety concern
2 Mar, 2021 | 02:06h | UTC
Commentary on Twitter
⛔A new safety concern⛔
New ? post-marketing study @CMIJournal suggests that the use of remdesivir is significantly associated with an increased risk of reporting serious bradycardia compared with HCQ,LPV/RTV, tocilizumab or glucocorticoids #IDTwitter https://t.co/npLMchifEM— Antibiotic Steward? Bassam Ghanem (@ABsteward) February 27, 2021
Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19
2 Mar, 2021 | 01:54h | UTCSummary: Can symptoms and medical examination accurately diagnose COVID-19? – Cochrane Library
We’ve updated our review on signs and symptoms for diagnosing Covid-19. Now includes evidence on loss of smell or taste #redflag @deeksj @leeflang_m @devymaye @SabineDittrich @jacdinnes https://t.co/P4hBbuL0x9
— Ann Van den Bruel (@annvdbruel) February 24, 2021
Consensus Document: Venous thromboembolism prophylaxis in the trauma intensive care unit
2 Mar, 2021 | 01:52h | UTC
Vaccinating the oldest against COVID-19 saves both the most lives and most years of life
2 Mar, 2021 | 02:04h | UTCCommentary: Vaccinating Oldest First for COVID Saves the Most Lives: Study – HealthDay
Commentary on Twitter
The policy of vaccinating the oldest vs covid-19:
Most lives saved and most years of life saved, the latter representing an unexpected extent of life expectancy gainhttps://t.co/KgLrl1j2xt @PNASNews by @jrgoldstein1 and colleagues pic.twitter.com/4MWZRa1i11— Eric Topol (@EricTopol) February 25, 2021
Guideline: Treatment of methicillin-resistant Staphylococcus aureus (MRSA)
2 Mar, 2021 | 01:50h | UTC
Commentary on Twitter
We're delighted to publish the first update of UK #MRSA guidelines in more than a decade. Please share with your contacts & colleagues .
Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UKhttps://t.co/3o3OVIdLuB #JACAMRNews #IDtwitter pic.twitter.com/GGlv1C1T1g
— JAC-AMR (@jac_amr) February 4, 2021
Who gets a COVID-19 vaccine and who pays? The need for economic analysis
2 Mar, 2021 | 02:02h | UTC
Commentary on Twitter
NEW from @CGDev and @idsihealth — experts look at the potential of Health Technology Assessment (HTA) on informing how much #COVID19 vaccine countries should buy, who should pay, and how vaccines can be most effectively delivered.
Read: https://t.co/KuMZSARSEF #GlobalHealth
— Center for Global Development (@CGDev) February 24, 2021
Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies
2 Mar, 2021 | 01:44h | UTCNews release: The right ‘5-a-day’ mix is 2 fruit and 3 vegetable servings for longer life – American Heart Association
Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge
2 Mar, 2021 | 01:46h | UTC
Commentary on Twitter
“Direct oral challenge safe & effective for de-labelling patients at low risk for true allergy. Important for optimizing patient care and tackling #AMR” https://t.co/S3VL8JXyFJ #JACAMRNews #AMR #AMS @SAPGAbx @lac_cooper @jenny_harbour @raseaton66 @jacquisneddons pic.twitter.com/SwE1yyVr8d
— JAC-AMR (@jac_amr) February 23, 2021
RCT: Similar outcomes with intermittent vs. continuous pulse oximetry in hospitalized infants with stabilized bronchiolitis
2 Mar, 2021 | 01:42h | UTCIntermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Editorial: Should We Prioritize Deimplementation of Continuous Pulse Oximetry in Bronchiolitis Care?
M-A: Glue vs. mechanical mesh fixation in laparoscopic inguinal hernia repair
2 Mar, 2021 | 01:29h | UTC
Cohort study: Recovery of consciousness and functional outcome in moderate and severe traumatic brain injury
2 Mar, 2021 | 01:34h | UTCRecovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury – JAMA Neurology (free for a limited period)
Editorial: Holding Out Hope After Traumatic Brain Injury (free for a limited period)
Commentary on Twitter
In this study in @JAMANeuro:
most individuals who became comatose after moderate/severe traumatic brain injury recovered consciousness and ~50% regained functional independence, cautioning early decisions to withdraw/withhold treatment in these patients. https://t.co/jIz38AwCXO— Saleh Almenawer, MD (@SAlmenawer) March 1, 2021
Cohort study: Association between preterm-birth phenotypes and differential morbidity, growth, and neurodevelopment at age 2 years
2 Mar, 2021 | 01:41h | UTC
Teleneurology-enabled determination of death by neurologic criteria after cardiac arrest or severe neurologic injury
2 Mar, 2021 | 01:32h | UTCTeleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury – Neurology (link to abstract – $ for full-text)
RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury
2 Mar, 2021 | 01:30h | UTCA randomized trial comparing prescribed light exercise to standard management for emergency department patients with acute mild traumatic brain injury – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentary: Exercise After Concussion in Adults? – Journal Feed
Laparoscopic Roux-en-Y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials
2 Mar, 2021 | 01:27h | UTCVisual abstract: Merged SLEEVEPASS and SM-BOSS trials
M-A: Umbilical cord management at term and late preterm birth
2 Mar, 2021 | 01:25h | UTCUmbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
To beta-amyloid or not to beta-amyloid? An innovative meta-analysis offers new insight into Alzheimer’s drugs
2 Mar, 2021 | 01:18h | UTCOriginal study: Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis – The BMJ
Commentary on Twitter
Anti-amyloid therapy is unlikely to be effective in #Alzheimer’s disease.
Meta-analysis of 14 RCTs found that reducing amyloid levels is associated with little, if any, improvement in cognition.
It’s time for a new paradigm.#GeriTwitter
https://t.co/ZlL39Ondkp— Art Walaszek (@artwalaszek) February 26, 2021
Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis
2 Mar, 2021 | 01:24h | UTCPhase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
The tubulin polymerization and Src kinase inhibitor tirbanibulin was superior to placebo ointment in clearing actinic keratoses on the face and scalp at 2 months. As is typical of the disorder, lesions recurred in 47% of patients at 1 year.
— NEJM (@NEJM) February 17, 2021
RCT: 3-Year outcomes of transcatheter mitral valve repair in patients with heart failure
2 Mar, 2021 | 01:20h | UTC3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: 3-Year Outcomes of Transcatheter Mitral Valve Repair in Heart Failure – American College of Cardiology