Urology
Johns Hopkins Performs First Total Penis and Scrotum Transplant in the World
25 Apr, 2018 | 12:42h | UTCCommentaries: ‘Whole Again’: A Vet Maimed by an I.E.D. Receives a Transplanted Penis – The New York Times (10 articles per month are free) AND Veteran Receives Penis Transplant To Repair War Wound – NPR (free)
Randomized Trial: 5-Day Nitrofurantoin vs Single-Dose Fosfomycin in Uncomplicated Lower UTI
23 Apr, 2018 | 21:13h | UTCEditorial: Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis – JAMA (free)
Research: Low-Dose Abiraterone With Food vs Standard Dose Abiraterone In Prostate Cancer
20 Apr, 2018 | 01:44h | UTCCommentaries: Taking a Standard Prostate Cancer Drug with Food Boosts Impact, Lowers Cost – University of Chicago Medical Center, via NewsWise (free) AND Low-Dose Prostate Drug Can Match Standard Dose, Cut Costs – Medscape (free registration required)
Related: Tackling the High Cost of Cancer Care (free commentaries issued when this paper was first presented at the 2017 ASCO annual meeting)
“Savings per patient could reach as high as $300,000” (from NewsWise)
Guidelines for the antibiotic treatment of community-acquired urinary tract infections
13 Apr, 2018 | 01:40h | UTC
WHO recommendation on duration of bladder catheterization after surgical repair of simple obstetric urinary fistula
13 Apr, 2018 | 00:53h | UTCGuideline: WHO Recommendation on Duration of Bladder Catheterization After Surgical Repair of Simple Obstetric Urinary Fistula – World Health Organization (free)
Review of guidelines: surgical management of urolithiasis
13 Apr, 2018 | 00:49h | UTCSurgical management of urolithiasis – a systematic analysis of available guidelines – BMC Urology (free)
Guideline: evaluation and management of testosterone deficiency
12 Apr, 2018 | 02:29h | UTCGuideline: Evaluation and Management of Testosterone Deficiency – American Urological Association (free)
Commentary: AUA: New Guidelines for Diagnosis, Management of Testosterone Deficiency – MPR (free)
Related Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Systematic review: alpha-blockers as medical expulsive therapy for ureteral stones
12 Apr, 2018 | 01:56h | UTCAlpha-blockers as medical expulsive therapy for ureteral stones – Cochrane Library (link to abstract – $ for full-text)
Summary: Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease – Cochrane Library (free)
Randomized controlled trial: acupuncture versus titrated morphine in acute renal colic
11 Apr, 2018 | 01:19h | UTCSource: EvidenceAlerts
Randomized trial: nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma
6 Apr, 2018 | 01:34h | UTCNivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma – NEJM (link to abstract – $ for full-text)
Quick Take Video Summary: Sunitinib or Nivolumab plus Ipilimumab for Renal-Cell Carcinoma (free)
“Overall survival and objective response rates were significantly higher with nivolumab plus ipilimumab”.
ASCO guideline: anticancer therapy in metastatic non-castrate prostate cancer
6 Apr, 2018 | 01:05h | UTC
Effect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer
30 Mar, 2018 | 03:37h | UTCEffect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer: The NRG Oncology RTOG 0126 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentaries: Higher-dose RT lowers risk of recurrence but does not improve survival for men with prostate cancer – eCancer News (free) AND Higher doses of radiation don’t improve overall survival for prostate cancer patients – OnMedica (free) AND Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa – Renal & Urology News (free) AND Higher Doses of Radiation Don’t Improve Survival in Prostate Cancer – Washington University in St. Louis, via NewsWise (free)
Research: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis
23 Mar, 2018 | 01:53h | UTCMRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis – New England Journal of Medicine (free)
Commentaries: Prostate MRI reveals more treatable cancers, reduces overdiagnosis than standard biopsy – European Urology Association, via EurekAlert (free) AND MRI Before Biopsy Better Than TRUS in Prostate Cancer – Medscape (free registration required)
Research: Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients
23 Mar, 2018 | 01:52h | UTCCommentaries: HCV Prophylaxis Could Expand Kidney Availability – Renal & Urology News (free) AND HCV-infected kidney donors could save lives – 2 Minute Medicine (free) AND One year posttransplant, recipients of hepatitis C kidneys disease-free – Johns Hopkins Medicine, ScienceDaily (free)
Guideline: Testosterone Therapy in Men With Hypogonadism
23 Mar, 2018 | 01:47h | UTCClinical Guideline Synopsis: Evaluation and Treatment of Male Hypogonadism – JAMA (free)
Original Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Commentary: New Testosterone Treatment Guidelines ‘Useful but Not Gospel’ – Medscape (free registration required)
Research: Effect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer
22 Mar, 2018 | 23:48h | UTCEffect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer: The NRG Oncology RTOG 0126 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentaries: Higher doses of radiation don’t improve survival in prostate cancer: Side effects also a concern – Washington University School of Medicine, via ScienceDaily (free) AND Higher doses of radiation don’t improve overall survival for prostate cancer patients – OnMedica (free)
Meta-Analysis: Digital Rectal Examination for Prostate Cancer Screening in Primary Care
16 Mar, 2018 | 02:26h | UTCCommentaries: New analysis recommends against using digital rectal exam in primary care – American Academy of Family Physicians, vie EurekAlert (free) AND Little Evidence Supports Use of Digital Rectal Exam – Medscape (free registration required) AND Digital Rectal Exams for Routine Prostate Screening Discouraged – NEJM Physician’s First Watch (free)
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)
Are you ready for the ATLS 10th Edition Updates?
23 Feb, 2018 | 01:11h | UTCAre you ready for the ATLS 10th Edition Updates? – emDocs (free)
Related: Infographic: ATLS Trauma Update 2018
Research: Robot-assisted radical prostatectomy vs laparoscopic and open retropubic radical prostatectomy
22 Feb, 2018 | 23:36h | UTCCommentary: After-effects not necessarily reduced with robotic prostate surgery – Reuters (free)
Related Cochrane Review with similar results: Laparoscopic and robotic-assisted versus open radical prostatectomy for the treatment of localised prostate cancer – Cochrane Library (free)
Research: Potential Yield of Imminent Death Kidney Donation
22 Feb, 2018 | 22:47h | UTCPotential Yield of Imminent Death Kidney Donation – American Journal of Transplantation, via Medscape (free registration required)
Guidelines on Adult Testosterone Deficiency
22 Feb, 2018 | 21:53h | UTCSource: New Clinical Practice Guidelines, February 2018 – Medscape (free registration required)
Research: Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer
16 Feb, 2018 | 01:34h | UTC“Apalutamide improves castration resistant prostate CA survival compared with… placebo. Why wasn’t it compared w bicalutamide?” (via @RichardLehman1 see Tweet). See Richard Lehman’s point of view
Urothelial Carcinoma: The Evolving Landscape of Immunotherapy for Patients with Advanced Disease
16 Feb, 2018 | 00:32h | UTC
EAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence
9 Feb, 2018 | 12:20h | UTCEAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence – European Urology (free)