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Rheumatology

Review: Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease

24 Nov, 2019 | 20:36h | UTC

Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease: Current Concepts for the Diagnosis and Treatment – Frontiers in Medicine (free)

 


#ACR19 – Randomized Trial: Low-Dose Corticosteroids for Short Periods Effective and Safe for Hand Osteoarthritis

12 Nov, 2019 | 11:23h | UTC

Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)

Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Randomized Trial: Methotrexate May Reduce Joint Damage Progression in Erosive Hand Osteoarthritis

12 Nov, 2019 | 10:49h | UTC

Methotrexate Significantly Reduces Joint Damage Progression Over Placebo in Erosive Hand OA, and May Facilitate Bone Remodeling – American College of Rheumatology (free)

Abstract: Methotrexate in Patients with Hand Erosive Osteoarthritis Refractory to Usual Treatments: A Randomized, Double-blind, Placebo-controlled Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Randomized Trial: Ultrasound to Guide Treatment Strategy Not Beneficial in Early Rheumatoid Arthritis

12 Nov, 2019 | 10:46h | UTC

Ultrasound to Guide Treatment Strategy Not Beneficial in Early RA – American College of Rheumatology (free)

Abstract: Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Study: Hydroxychloroquine May Reduce the Risk of Recurrent Congenital Heart Block in Subsequent Pregnancies of Women with Anti-SSA/Ro Antibodies

12 Nov, 2019 | 10:48h | UTC

Physicians Should Consider Hydroxychloroquine to Reduce the Risk of Recurrent Congenital Heart Block in Subsequent Pregnancies of Women with Anti-SSA/Ro Antibodies – American College of Rheumatology (free)

Abstract: The Prospective Open Label Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH) Study Demonstrates a Reduction in the Recurrence Rate of Advanced Block (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Study: Gadolinium-Enhanced MRI of Shoulders May Improve Diagnostic Accuracy and Predict Polymyalgia Rheumatica Recurrence

12 Nov, 2019 | 10:45h | UTC

Gadolinium-Enhanced MRI of Shoulders Improves Diagnostic Accuracy and Helps Predict Polymyalgia Rheumatica Recurrence – American College of Rheumatology (free)

Abstract: Gadolinium-Enhanced Magnetic Resonance Imaging in Shoulders Contributes Accurate Diagnosis and Predicting Recurrence to Patients with Polymyalgia Rheumatica (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Meta-Analysis: For People with Osteoarthritis, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit

12 Nov, 2019 | 10:48h | UTC

For People with OA, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit – American College of Rheumatology (free)

Abstract: Is There Any Role for Opioids in the Management of OA? (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Cohort Study: Half of People with Rheumatoid Arthritis Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment

12 Nov, 2019 | 10:45h | UTC

Half of People with RA Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment – American College of Rheumatology (free)

Abstract: Risk of Immunotherapy Related Toxicity in Patients with Rheumatoid Arthritis (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


A Systematic Review of Guidelines for Managing Rheumatoid Arthritis

5 Nov, 2019 | 08:52h | UTC

A systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)

Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)

 


EULAR Recommendations for the Management of Sjögren’s Syndrome

4 Nov, 2019 | 01:23h | UTC

EULAR recommendations for the management of Sjögren’s syndrome with topical and systemic therapies – Annals of Rheumatic Disease (free)

Related Guideline: The British Society for Rheumatology guideline for the management of adults with primary Sjögren’s Syndrome – Rheumatology (free)

 


Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?

4 Nov, 2019 | 01:19h | UTC

Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis – British Journal of Sports Medicine (free)

 

Related Commentary on Twitter

 


Randomized Trial: Naproxen vs. Colchicine for the Treatment of Gout Flares in Primary Care

4 Nov, 2019 | 01:13h | UTC

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care – Annals of Rheumatic Diseases (free)

 

Related Commentary on Twitter

 


Randomized Trial: Severe Energy Restriction Associated with Increased Bone Loss when Compared with Moderate Energy Restriction

3 Nov, 2019 | 19:48h | UTC

Effect of Weight Loss via Severe vs Moderate Energy Restriction on Lean Mass and Body Composition Among Postmenopausal Women With Obesity: The TEMPO Diet Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)

 


Meta-Analysis: Calcium Supplementation May Increase the Risk of Myocardial Infarction

1 Nov, 2019 | 07:42h | UTC

The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials – Journal of the American College of Nutrition (free)

Related Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)

See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)

 


Rheumatology – One Year in Review 2019

29 Oct, 2019 | 02:20h | UTC

One Year in Review 2019 – Clinical and Experimental Rheumatology (free PDF articles)

– Systemic sclerosis

– Sjögren’s syndrome

– Systemic lupus erythematosus

– Pathogenesis of rheumatoid arthritis

– Vasculitis

– Novelties in the treatment of rheumatoid arthritis

– Fibromyalgia

 


Cohort Study: Association of Physical Activity and Fracture Risk Among Postmenopausal Women

29 Oct, 2019 | 02:12h | UTC

Association of Physical Activity and Fracture Risk Among Postmenopausal Women – JAMA Network Open (free)

Invited Commentary: Analyses of Physical Activity and Health—Are Our Methods Too Sedentary? – JAMA Network Open (free)

 


Review: Ocular Manifestations of Rheumatic Diseases

25 Oct, 2019 | 08:08h | UTC

Ocular manifestations of rheumatic diseases – International Ophthalmology (free)

 


Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures

23 Oct, 2019 | 08:18h | UTC

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open (free)

Commentary: Network meta-analysis nixes bone benefit from vitamin D, calcium – Univadis (free registration required)

Related Meta-Analysis: Calcium or Vitamin D Supplementation and Fracture Incidence in Older Adults – JAMA (free study and commentaries)

 


[Abstract Only] Study: Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy

23 Oct, 2019 | 07:22h | UTC

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy – Arthritis & Rheumatology (link to abstract – $ for full-text)

Commentaries: Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus – Physician’s Weekly (free) AND Monitoring blood hydroxychloroquine levels beneficial in SLE – Medwire News (free)

 


Meta-Analysis: Interleukin Inhibitors Increase the Risk of Infections and Cancer in Patients with Rheumatologic Diseases

22 Oct, 2019 | 07:38h | UTC

Risk of Infections and Cancer in Patients with Rheumatologic Diseases Receiving Interleukin Inhibitors: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentary: Interleukin Targeted Biologics Increase Risks of Infection – RheumNow (free)

 


Recommendations on Investigation and Diagnosis of Systemic Autoimmune Myopathies

22 Oct, 2019 | 07:33h | UTC

The Brazilian Society of Rheumatology recommendations on investigation and diagnosis of systemic autoimmune myopathies – Advances in Rheumatology (free)

Related: Polymyositis and Dermatomyositis – Challenges in Diagnosis and Management (free reviews and guidelines)

 


The Global Burden of Musculoskeletal Pain—Where to From Here?

22 Oct, 2019 | 07:25h | UTC

The Global Burden of Musculoskeletal Pain—Where to From Here? – American Journal of Public Health (free)

Related: Study: Musculoskeletal Conditions are Now the Second Global Cause of Years Lived with Disability (link to abstract and commentary)

 


Randomized Trial: Antibiotics Not Effective for the Treatment of Chronic Low Back Pain and Modic Changes

20 Oct, 2019 | 22:29h | UTC

Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial – The BMJ (free)

Commentary: Amoxicillin for Chronic Low Back Pain? Are You Kidding Me? In Defense of a Controversial Clinical Trial – HIV and ID Observations (free)

 


Short Review: Bisphosphonates for Postmenopausal Osteoporosis

20 Oct, 2019 | 22:23h | UTC

Bisphosphonates for Postmenopausal Osteoporosis – JAMA (free for a limited period)

 


Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought?

17 Oct, 2019 | 08:21h | UTC

Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought? – Radiology (free)

Commentary: New evidence that hip and knee steroid injections more dangerous than thought – Boston University School of Medicine (free)

 


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