Rheumatology
[Abstract Only] Randomized Trial: Adverse Effects of Low-Dose Methotrexate
18 Feb, 2020 | 08:08h | UTCAdverse Effects of Low-Dose Methotrexate: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study investigates rates of adverse events for common rheumatoid arthritis drug – Brigham and Women’s Hospital (free) AND Low-dose methotrexate use ‘has inherent risks’ – Medicine Matters (free)
Immunization Strategies to Span the Spectrum of Immunocompromised Adults
16 Feb, 2020 | 20:43h | UTCImmunization Strategies to Span the Spectrum of Immunocompromised Adults – Mayo Clinic Proceedings (free)
[Abstract Only] Randomized Trial: Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis
13 Feb, 2020 | 08:00h | UTCPlasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Plasma Exchange and Glucocorticoids for ANCA-Associated Vasculitis (free)
Commentary: PEXIVAS: No benefit of plasma exchange in ANCA-associated vasculitis – Medicine Matters (free)
Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism
9 Feb, 2020 | 20:45h | UTCDiagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)
Related Commentary on Twitter
JAMA Insights: the presentation and diagnostic workup of primary #hyperparathyroidism, and indications for surgical vs surveillance management. https://t.co/kUg9WeCCsc
— JAMA (@JAMA_current) February 8, 2020
Randomized Trial: Very Early Etanercept + MTX vs. MTX with Delayed Etanercept in Rheumatoid Arthritis
7 Feb, 2020 | 08:12h | UTCCommentary: Start with Anti-TNF in RA? Not So Fast – RheumNow (free)
Sex Differences in Systemic Lupus Erythematosus: Epidemiology, Clinical Considerations, and Disease Pathogenesis
7 Feb, 2020 | 07:53h | UTC
EULAR Recommendations for the Management of Rheumatoid Arthritis with Synthetic and Biological Disease-modifying Antirheumatic Drugs
28 Jan, 2020 | 09:09h | UTC
BSR Guideline on Diagnosis and Treatment of Giant Cell Arteritis
26 Jan, 2020 | 22:54h | UTCExecutive Summary: British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis – Rheumatology (free)
Related: Giant Cell Arteritis: An Updated Review of an Old Disease (free review and guidelines)
Randomized Trial: Methotrexate Effect on Immunogenicity and Long-term Maintenance of Adalimumab in Axial Spondyloarthritis
22 Jan, 2020 | 09:10h | UTC
Editorial – Back to Basics: 10 Facts Every Person Should Know About Back Pain
21 Jan, 2020 | 03:04h | UTCCommentary: Myths may worsen low back pain and promote ineffective treatments – Reuters (free)
Recommendations for the Management of Psoriatic Arthritis in Resource-poor Settings
19 Jan, 2020 | 21:01h | UTC
Addendum to BSH Guidelines on Investigation and Management of Antiphospholipid Syndrome: Use of Direct Acting Oral Anticoagulants
19 Jan, 2020 | 20:55h | UTCRelated: Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome (link to abstract and commentaries)
[Abstract Only] Randomized Trial: Anifrolumab in Active Systemic Lupus Erythematosus
17 Jan, 2020 | 09:39h | UTCTrial of Anifrolumab in Active Systemic Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: TULIP2 – Anifrolumab Succeeds in Lupus – RheumNow (free)
Review: Periodic Fever Syndromes and the Autoinflammatory Diseases
17 Jan, 2020 | 02:06h | UTC
[Abstract Only] Randomized Trial: Ixekizumab for Patients with Non-radiographic Axial Spondyloarthritis
16 Jan, 2020 | 02:29h | UTCIxekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary: #VisualAbstract: Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X) – 2 Minute Medicine (free)
In this week's issue—Ixekizumab was superior to placebo for improving signs and symptoms in patients with non-radiographic axial spondyloarthritis at weeks 16 and 52: COAST-X, a randomised, placebo-controlled trial https://t.co/XuKDKGJns0 pic.twitter.com/bbuOReLCu2
— The Lancet (@TheLancet) January 8, 2020
Systematic Review: Surgery for Rotator Cuff Tears
15 Jan, 2020 | 00:55h | UTCSurgery for rotator cuff tears – Cochrane Library (free)
Summary: Does repair of torn rotator cuff tendons work? – Cochrane Library (free)
Related: BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes (free guideline and other resources)
Related Commentary on Twitter
Compared with non-surgical treatment, rotator cuff repair surgery may provide little or no clinically important benefits for patients in relation to important outcomes like pain, function, & overall quality of life: https://t.co/l0fuGRXNCk The latest evidence from @CochraneMSK pic.twitter.com/UXx2ij2rwf
— The Cochrane Library (@CochraneLibrary) December 18, 2019
[Abstract Only] Meta-Analysis: Opioids Not Beneficial for Chronic Osteoarthritis Pain
14 Jan, 2020 | 00:23h | UTCOpioids for chronic osteoarthritis pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration – European Journal of Pain (link to abstract – $ for full-text)
Related Systematic Review: Oral or transdermal opioids for osteoarthritis of the knee or hip – Cochrane Library (free)
Randomized Trial: A Head-to-head Comparison of the Efficacy and Safety of Ixekizumab and Adalimumab in Biological-naïve Patients with Active Psoriatic Arthritis
14 Jan, 2020 | 00:02h | UTCCommentary: We Have a Winner: Head-to-Head Study Compares Biologics for PsA – MedPage Today (free registration required)
An Overview of Autoantibodies in Rheumatoid Arthritis
12 Jan, 2020 | 20:59h | UTCAn overview of autoantibodies in rheumatoid arthritis – Journal of Autoimmunity (free)
ACR Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
9 Jan, 2020 | 01:29h | UTCNews Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)
[Abstract Only] Randomized Trial: Maintaining Low-dose Prednisone in SLE Patients with Inactive Disease Prevents Relapse
8 Jan, 2020 | 01:21h | UTCWithdrawal of low-dose prednisone in SLE patients with a clinically quiescent disease for more than 1 year: a randomised clinical trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: Fewer Lupus Flares on Low Dose Steroids – RheumNow (free)
New ACR/EULAR Classification Criteria for IgG4‐Related Disease
6 Dec, 2019 | 10:26h | UTCCommentary: ACR and EULAR release new classification criteria for IgG4-related disease – American College of Rheumatology (free)
Study: Smoking Cessation is Associated with Lower Disease Activity in Rheumatoid Arthritis Patients
5 Dec, 2019 | 10:34h | UTCCommentary: Smoking Cessation Lowers RA Disease Activity and CV Risks – RheumNow (free)
Meta-analysis: Exercise Treatment Effect Modifiers in Persistent Low Back Pain
1 Dec, 2019 | 21:47h | UTC
Systematic Review: Clinical Risk Factors for Achilles Tendinopathy
24 Nov, 2019 | 20:38h | UTC