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Rheumatology

[Abstract Only] Randomized Trial: Ixekizumab for Patients with Non-radiographic Axial Spondyloarthritis

16 Jan, 2020 | 02:29h | UTC

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: #VisualAbstract: Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X) – 2 Minute Medicine (free)

 

https://twitter.com/TheLancet/status/1214872375822553088

 


Systematic Review: Surgery for Rotator Cuff Tears

15 Jan, 2020 | 00:55h | UTC

Surgery for rotator cuff tears – Cochrane Library (free)

Summary: Does repair of torn rotator cuff tendons work? – Cochrane Library (free)

Related: BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes (free guideline and other resources)

 

Related Commentary on Twitter

 


[Abstract Only] Meta-Analysis: Opioids Not Beneficial for Chronic Osteoarthritis Pain

14 Jan, 2020 | 00:23h | UTC

Opioids for chronic osteoarthritis pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration – European Journal of Pain (link to abstract – $ for full-text)

Related Systematic Review: Oral or transdermal opioids for osteoarthritis of the knee or hip – Cochrane Library (free)

 


Randomized Trial: A Head-to-head Comparison of the Efficacy and Safety of Ixekizumab and Adalimumab in Biological-naïve Patients with Active Psoriatic Arthritis

14 Jan, 2020 | 00:02h | UTC

A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial – Annals of Rheumatic Diseases (free)

Commentary: We Have a Winner: Head-to-Head Study Compares Biologics for PsA – MedPage Today (free registration required)

 


An Overview of Autoantibodies in Rheumatoid Arthritis

12 Jan, 2020 | 20:59h | UTC

An overview of autoantibodies in rheumatoid arthritis – Journal of Autoimmunity (free)

 


ACR Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

9 Jan, 2020 | 01:29h | UTC

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee – Arthritis & Rheumatology (free)

News Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)

 


[Abstract Only] Randomized Trial: Maintaining Low-dose Prednisone in SLE Patients with Inactive Disease Prevents Relapse

8 Jan, 2020 | 01:21h | UTC

Withdrawal of low-dose prednisone in SLE patients with a clinically quiescent disease for more than 1 year: a randomised clinical trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: Fewer Lupus Flares on Low Dose Steroids – RheumNow (free)

 


New ACR/EULAR Classification Criteria for IgG4‐Related Disease

6 Dec, 2019 | 10:26h | UTC

The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4‐Related Disease – Arthritis & Rheumatology (free)

Commentary: ACR and EULAR release new classification criteria for IgG4-related disease – American College of Rheumatology (free)

 


Study: Smoking Cessation is Associated with Lower Disease Activity in Rheumatoid Arthritis Patients

5 Dec, 2019 | 10:34h | UTC

Smoking cessation is associated with lower disease activity and predicts cardiovascular risk reduction in rheumatoid arthritis patients – Rheumatology (free)

Commentary: Smoking Cessation Lowers RA Disease Activity and CV Risks – RheumNow (free)

 


Meta-analysis: Exercise Treatment Effect Modifiers in Persistent Low Back Pain

1 Dec, 2019 | 21:47h | UTC

Exercise treatment effect modifiers in persistent low back pain: an individual participant data meta-analysis of 3514 participants from 27 randomised controlled trials – British Journal of Sports Medicine (free)

 


Systematic Review: Clinical Risk Factors for Achilles Tendinopathy

24 Nov, 2019 | 20:38h | UTC

Clinical risk factors for Achilles tendinopathy: a systematic review – British Journal of Sports Medicine (free)

 


Review: Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease

24 Nov, 2019 | 20:36h | UTC

Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease: Current Concepts for the Diagnosis and Treatment – Frontiers in Medicine (free)

 


#ACR19 – Randomized Trial: Low-Dose Corticosteroids for Short Periods Effective and Safe for Hand Osteoarthritis

12 Nov, 2019 | 11:23h | UTC

Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)

Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Randomized Trial: Methotrexate May Reduce Joint Damage Progression in Erosive Hand Osteoarthritis

12 Nov, 2019 | 10:49h | UTC

Methotrexate Significantly Reduces Joint Damage Progression Over Placebo in Erosive Hand OA, and May Facilitate Bone Remodeling – American College of Rheumatology (free)

Abstract: Methotrexate in Patients with Hand Erosive Osteoarthritis Refractory to Usual Treatments: A Randomized, Double-blind, Placebo-controlled Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Randomized Trial: Ultrasound to Guide Treatment Strategy Not Beneficial in Early Rheumatoid Arthritis

12 Nov, 2019 | 10:46h | UTC

Ultrasound to Guide Treatment Strategy Not Beneficial in Early RA – American College of Rheumatology (free)

Abstract: Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Study: Hydroxychloroquine May Reduce the Risk of Recurrent Congenital Heart Block in Subsequent Pregnancies of Women with Anti-SSA/Ro Antibodies

12 Nov, 2019 | 10:48h | UTC

Physicians Should Consider Hydroxychloroquine to Reduce the Risk of Recurrent Congenital Heart Block in Subsequent Pregnancies of Women with Anti-SSA/Ro Antibodies – American College of Rheumatology (free)

Abstract: The Prospective Open Label Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH) Study Demonstrates a Reduction in the Recurrence Rate of Advanced Block (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Study: Gadolinium-Enhanced MRI of Shoulders May Improve Diagnostic Accuracy and Predict Polymyalgia Rheumatica Recurrence

12 Nov, 2019 | 10:45h | UTC

Gadolinium-Enhanced MRI of Shoulders Improves Diagnostic Accuracy and Helps Predict Polymyalgia Rheumatica Recurrence – American College of Rheumatology (free)

Abstract: Gadolinium-Enhanced Magnetic Resonance Imaging in Shoulders Contributes Accurate Diagnosis and Predicting Recurrence to Patients with Polymyalgia Rheumatica (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Meta-Analysis: For People with Osteoarthritis, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit

12 Nov, 2019 | 10:48h | UTC

For People with OA, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit – American College of Rheumatology (free)

Abstract: Is There Any Role for Opioids in the Management of OA? (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


#ACR19 – [Not Published Yet] Cohort Study: Half of People with Rheumatoid Arthritis Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment

12 Nov, 2019 | 10:45h | UTC

Half of People with RA Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment – American College of Rheumatology (free)

Abstract: Risk of Immunotherapy Related Toxicity in Patients with Rheumatoid Arthritis (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

 


A Systematic Review of Guidelines for Managing Rheumatoid Arthritis

5 Nov, 2019 | 08:52h | UTC

A systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)

Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)

 


EULAR Recommendations for the Management of Sjögren’s Syndrome

4 Nov, 2019 | 01:23h | UTC

EULAR recommendations for the management of Sjögren’s syndrome with topical and systemic therapies – Annals of Rheumatic Disease (free)

Related Guideline: The British Society for Rheumatology guideline for the management of adults with primary Sjögren’s Syndrome – Rheumatology (free)

 


Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?

4 Nov, 2019 | 01:19h | UTC

Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis – British Journal of Sports Medicine (free)

 

Related Commentary on Twitter

 


Randomized Trial: Naproxen vs. Colchicine for the Treatment of Gout Flares in Primary Care

4 Nov, 2019 | 01:13h | UTC

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care – Annals of Rheumatic Diseases (free)

 

Related Commentary on Twitter

 


Randomized Trial: Severe Energy Restriction Associated with Increased Bone Loss when Compared with Moderate Energy Restriction

3 Nov, 2019 | 19:48h | UTC

Effect of Weight Loss via Severe vs Moderate Energy Restriction on Lean Mass and Body Composition Among Postmenopausal Women With Obesity: The TEMPO Diet Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)

 


Meta-Analysis: Calcium Supplementation May Increase the Risk of Myocardial Infarction

1 Nov, 2019 | 07:42h | UTC

The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials – Journal of the American College of Nutrition (free)

Related Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)

See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)

 


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