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Rheumatology

Recommended musculoskeletal and sports ultrasound terminology: a Delphi-based consensus statement.

4 Feb, 2022 | 08:51h | UTC

Recommended musculoskeletal and sports ultrasound terminology: a Delphi-based consensus statement – British Journal of Sports Medicine

News Release: Multiple Societies Provide Support for New Consensus Statement on Musculoskeletal and Sports Ultrasound Terminology – American Medical Society for Sports Medicine

 

Commentary on Twitter

 


Hyaluronic acid injections have increased for knee arthritis in the US, despite guideline recommendations against their use.

4 Feb, 2022 | 08:32h | UTC

Hyaluronic Acid Injections for Knee Osteoarthritis: Has Utilization Among Medicare Beneficiaries Changed Between 2012 and 2018? – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

News Release: Hyaluronic acid injections have increased for knee arthritis – despite recommendations against their use

Related Guideline: Treatment of Osteoarthritis of the Knee: Evidence-Based Guideline, 2nd Edition – Journal of the American Academy of Orthopaedic Surgeons

 


An observational study including 15.670 people using methotrexate and 2.689 using leflunomide showed the incidences of discontinuation related to cytopenia, liver enzyme elevation, or kidney function decline.

4 Feb, 2022 | 08:21h | UTC

What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline? – Rheumatology

 


Psychosis in systemic lupus erythematosus (SLE): a 40-year experience of a specialist center showed most patients (66.7%) had full remission with a combination of antipsychotics and immunosuppressive therapy.

4 Feb, 2022 | 08:20h | UTC

Psychosis in systemic lupus erythematosus (SLE): 40-year experience of a specialist centre – Rheumatology

 


Review: Behçet syndrome.

3 Feb, 2022 | 08:29h | UTC

Behçet syndrome – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Behçet syndrome (if the link is paywalled, try this one)

Related: EULAR recommendations for the management of Behçet’s syndrome

 


RCT: Efficacy and safety of Risankizumab for active psoriatic arthritis.

2 Feb, 2022 | 08:23h | UTC

Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 1 trial – Annals of Rheumatic Diseases

 


Recommendations on the everyday management of patients with spondyloarthritis, including psoriatic arthritis.

1 Feb, 2022 | 08:44h | UTC

2022 French Society for Rheumatology (SFR) recommendations on the everyday management of patients with spondyloarthritis, including psoriatic arthritis – Joint Bone Spine

 


RCT: In patients with rheumatoid arthritis, treatment with oral drug Tofacitinib increases cardiovascular and cancer risk compared to treatment with subcutaneous TNF inhibitors.

1 Feb, 2022 | 08:35h | UTC

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)

Video: CV and Cancer Risk with Tofacitinib in RA – New England Journal of Medicine

Commentary: CV, Cancer Risk Up With Tofacitinib for Rheumatoid Arthritis – HealthDay

 


Systematic Review: Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases.

1 Feb, 2022 | 08:20h | UTC

Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider – RMD Open

 

Commentary on Twitter

 


RCT: Vitamin D supplementation for older adults (mean age 67 years) for 5 years reduced the risk of autoimmune diseases by 22%. Absolute risk in the treatment group was 0.95% vs. 1.19% in the placebo group.

30 Jan, 2022 | 14:30h | UTC

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial – The BMJ

Commentary: Vitamin D and fish oil supplements may help prevent autoimmune disease, study says – CNN

Related:

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

 


The 2021 EULAR and ACR points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS.

30 Jan, 2022 | 14:19h | UTC

The 2021 EULAR and ACR points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS – Annals of Rheumatic Diseases

 


Guideline Summary: Management of the top 10 most common immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.

30 Jan, 2022 | 14:11h | UTC

Management of the Top 10 Most Common Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy – JCO Oncology Practice

Original Article: ASCO Guideline Update: Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.

Related:

Clinical practice guideline on immune checkpoint inhibitor-related adverse events.

NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (several resources on the subject)

 


The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life.

28 Jan, 2022 | 08:30h | UTC

The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life – Clinical Rheumatology

 


Review: Juvenile idiopathic arthritis.

28 Jan, 2022 | 08:13h | UTC

Juvenile idiopathic arthritis – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Juvenile idiopathic arthritis (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Short-term glucocorticoid-related side effects and adverse reactions: a narrative review and practical approach.

27 Jan, 2022 | 09:18h | UTC

Short-term glucocorticoid-related side effects and adverse reactions: a narrative review and practical approach – Swiss Medical Weekly

 


Cohort Study: Among patients with resolved Hepatitis B infections and concomitant autoimmune disease, exposure to prednisone doses greater than 20 mg/day were associated with a high risk for HBV reactivation or hepatitis flare.

21 Jan, 2022 | 09:39h | UTC

Average corticosteroid dose and risk for HBV reactivation and hepatitis flare in patients with resolved hepatitis B infection – Annals of Rheumatic Disease (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Systematic Review: Comparison of clinical manifestations in rheumatoid arthritis vs. spondyloarthritis.

21 Jan, 2022 | 09:24h | UTC

Comparison of Clinical Manifestations in Rheumatoid Arthritis vs. Spondyloarthritis: A Systematic Literature Review – Rheumatology and Therapy

 


Consensus statements for the assessment and management of non-radiographic axial spondyloarthritis.

21 Jan, 2022 | 09:26h | UTC

Australian Consensus Statements for the Assessment and Management of Non-radiographic Axial Spondyloarthritis – Rheumatology and Therapy

 


Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis.

20 Jan, 2022 | 08:52h | UTC

Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis – Medicine

 


In a study with 1110 children with prolonged fever, MRP8/14 serum levels were validated as a diagnostic marker for systemic juvenile idiopathic arthritis.

14 Jan, 2022 | 08:07h | UTC

MRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever – Rheumatology (link to abstract – $ for full-text)

Commentary: It is about time: the first validated biomarker for early diagnosis of sJIA – Rheumatology

 


Phase 2 RCT: In patients with generalized pustular psoriasis, Spesolimab improved lesions at one week but was associated with infections and systemic drug reactions.

14 Jan, 2022 | 08:01h | UTC

Trial of Spesolimab for Generalized Pustular Psoriasis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Trial of Spesolimab for Generalized Pustular Psoriasis – Mount Sinai

 


RCT: In patients with immune-mediated inflammatory diseases (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn disease, or psoriasis) treated with Infliximab, a proactive therapeutic drug monitoring protocol was more likely to lead to sustained disease control.

14 Jan, 2022 | 07:57h | UTC

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach.

8 Jan, 2022 | 22:45h | UTC

Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach – Nature Reviews Rheumatology (if the link is paywalled, try this one)

 


Review: Large-vessel vasculitis.

8 Jan, 2022 | 22:50h | UTC

Large-vessel vasculitis – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Large-vessel vasculitis (if the link is paywalled, try this one)

 


Management of patellar tendinopathy: a systematic review and network meta-analysis of randomized studies.

16 Dec, 2021 | 08:35h | UTC

Management of patellar tendinopathy: a systematic review and network meta-analysis of randomised studies – BMJ Open Sport & Exercise Medicine

 


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