Systematic Reviews & Meta-analysis
SR | Chest physiotherapy for acute bronchiolitis in pediatric patients between 0 and 24 months old
10 Apr, 2023 | 13:32h | UTC
SR | Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years
6 Apr, 2023 | 13:06h | UTC
SR | Insufficient evidence on skin-sparing mastectomy efficacy and safety for breast cancer
6 Apr, 2023 | 13:04h | UTCSkin‐sparing mastectomy for the treatment of breast cancer – Cochrane Database of Systematic Reviews
SR | Induction of labor at or near term for suspected fetal macrosomia
6 Apr, 2023 | 12:55h | UTC
ACC/AHA blood pressure categories | Systematic review of adverse pregnancy outcomes in early pregnancy
6 Apr, 2023 | 12:53h | UTC
Commentary on Twitter
American College of Cardiology and American Heart Association blood pressure categories—a systematic review of the relationship with adverse pregnancy outcomes in the first half of pregnancy https://t.co/n3jWFLVYg5 pic.twitter.com/QzaWRyY4n5
— AJOG (@AJOG_thegray) March 31, 2023
M-A | Impact of antihypertensive therapy on maternal & neonatal outcomes in mild-moderate pregnancy hypertension
6 Apr, 2023 | 12:51h | UTC
M-A | Vaginal swab outperforms urine for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis
5 Apr, 2023 | 13:23h | UTC
M-A | The efficacy of topical prostaglandin analogs for hair loss
5 Apr, 2023 | 13:20h | UTC
SR | Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa
5 Apr, 2023 | 12:48h | UTC
M-A | Efficacy of flash glucose monitoring in type 1 and type 2 diabetes
5 Apr, 2023 | 12:46h | UTC
M-A | Efficacy of atropine for myopia control in children
5 Apr, 2023 | 12:45h | UTCRelated:
RCT | Effect of low-concentration atropine eyedrops vs. placebo on myopia incidence in children
Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.
RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.
RCT | Myopia control effect of repeated low-level red-light therapy in children.
M-A | No significant health benefits found for low-volume alcohol intake
4 Apr, 2023 | 13:48h | UTCSummary: This systematic review and meta-analysis aimed to investigate the association between alcohol use and all-cause mortality, taking into account potential sources of bias. The study analyzed data from 107 cohort studies published between January 1980 and July 2021, which included 4,838,825 participants and 425,564 deaths.
The study found no significant reductions in all-cause mortality risk for drinkers who consumed less than 25 grams of ethanol per day compared to lifetime nondrinkers. However, there was a significantly increased risk of all-cause mortality among female drinkers who drank 25 or more grams per day and male drinkers who drank 45 or more grams per day.
The analysis highlighted the importance of controlling for former drinker bias and misclassification errors and found sex differences in the risk of all-cause mortality.
In conclusion, the updated meta-analysis found no significantly reduced risk of all-cause mortality associated with low-volume alcohol consumption after adjusting for potential confounding factors. The study recommends that future longitudinal studies in this field should attempt to minimize lifetime selection biases by not including former and occasional drinkers in the reference group and by using younger cohorts at baseline.
Commentary: Drinking Alcohol Brings No Health Benefits, Study Finds – HealthDay
Related:
Prioritising action on alcohol for health and development – The BMJ
M-A | Evolution and refinement of magnetically guided sentinel lymph node detection in breast cancer
4 Apr, 2023 | 13:30h | UTC
M-A | Mediterranean & low-fat diets may reduce mortality and non-fatal MI in patients with high cardiovascular risk
3 Apr, 2023 | 13:59h | UTCSummary: This systematic review and network meta-analysis aimed to determine the relative efficacy of different diets for preventing mortality and major cardiovascular events in patients at increased risk of cardiovascular disease. The study identified 40 randomized trials with 35,548 participants across seven dietary programs.
Moderate certainty evidence showed that Mediterranean and low-fat diets, with or without physical activity or other interventions, reduced all-cause mortality and non-fatal myocardial infarction in patients with increased cardiovascular risk. Mediterranean diet programs were also likely to reduce stroke risk.
Other dietary programs generally were not superior to minimal intervention. When compared with one another, no convincing evidence was found that the Mediterranean diet was superior to the low-fat diets in preventing mortality or non-fatal myocardial infarction.
News Release: Benefits of Mediterranean and low fat diet programmes in patients at risk of cardiovascular disease – BMJ Newsroom
Commentary: Mediterranean, Low-Fat Diets Both Good for Health: Network Meta-analysis – TCTMD
SR | Risk factors for length of NICU stay of newborns
3 Apr, 2023 | 13:23h | UTCRisk factors for length of NICU stay of newborns: A systematic review – Frontiers in Pediatrics
M-A | Coronary vasospasm in ANOCA patients: Prevalence, clinical features and prognosis
3 Apr, 2023 | 13:21h | UTC
M-A | Effects of statin therapy on glycemic control and insulin resistance
31 Mar, 2023 | 13:45h | UTCRelated:
Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.
Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes
Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
M-A | Incidence and prognostic role of pleural effusion in patients with pulmonary embolism
31 Mar, 2023 | 13:40h | UTC
M-A | Impact of axillary lymph node dissection and sentinel lymph node biopsy on upper limb morbidity in breast cancer patients
31 Mar, 2023 | 13:30h | UTC
M-A | Test characteristics of ultrasound for the diagnosis of peritonsillar abscess
30 Mar, 2023 | 14:19h | UTC
Improving cascade outcomes for active TB | A global systematic review and meta-analysis of TB interventions
30 Mar, 2023 | 14:17h | UTC
M-A | Aggressive IV hydration may increase mortality risk in severe acute pancreatitis
29 Mar, 2023 | 13:26h | UTCSummary: This systematic review and meta-analysis investigated the outcomes of aggressive and non-aggressive intravenous hydration in patients with severe and non-severe acute pancreatitis (AP). The study included nine randomized controlled trials with a total of 953 participants.
The findings revealed that aggressive intravenous hydration significantly increased mortality risk in severe AP cases, and fluid-related complication risk in both severe and non-severe AP cases. However, the study has some limitations, as only one study with 249 participants was judged to have a low risk of bias in all domains, while the remaining eight studies had non-low risk of bias, raising concerns about the reliability of the findings.
Despite these concerns, the findings still suggest that more conservative intravenous fluid resuscitation protocols for AP may be preferable. Further research with more rigorous study designs is needed to provide robust evidence on the effectiveness of different intravenous hydration strategies in treating acute pancreatitis.
SR | Diagnostic accuracy of heart auscultation for detecting valve disease
29 Mar, 2023 | 13:23h | UTC
SR | Effect of antenatal corticosteroid administration-to-birth interval on maternal and newborn outcomes
29 Mar, 2023 | 13:22h | UTC
M-A | Effects of dexmedetomidine on postoperative sleep quality
29 Mar, 2023 | 13:17h | UTC