Systematic Reviews & Meta-analysis
Meta-Analysis: Infection Rate Among Nutritional Therapies for Acute Pancreatitis
31 Jul, 2019 | 01:15h | UTCRelated Meta-Analysis: Efficacy comparisons of enteral nutrition and parenteral nutrition in patients with severe acute pancreatitis: a meta-analysis from randomized controlled trials – Bioscience Reports (free) AND Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta-analysis – Medicine (free)
Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
Systematic Review: Early Enteral Nutrition Within 24 hours of Lower Gastrointestinal Surgery May Reduce the Length of Hospital Stay
30 Jul, 2019 | 01:20h | UTCEarly enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications – Cochrane Library (free)
Related Guidelines: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free) AND Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 (free) AND Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices – World Journal of Gastrointestinal Surgery (free)
“This review suggests that early enteral feeding may lead to a reduced postoperative length of stay, however cautious interpretation must be taken due to substantial heterogeneity and low-quality evidence.”
[Abstract Only] Meta-Analysis: Safety and Efficacy of Testosterone for Postmenopausal Women with Low Sexual Desire Causing Distress
29 Jul, 2019 | 20:45h | UTCSafety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Testosterone may significantly improve sexual function and sexual well-being in postmenopausal women – The Lancet (free) AND Testosterone can enhance libido in postmenopausal women, new research says – CNN (free)
Related Commentary on Twitter
Just online: Safety and efficacy of #testosterone for #women: a systematic review and meta-analysis of randomised controlled trial data https://t.co/xKp6RCKd0g #postmenopausal #menopause #sexual desire pic.twitter.com/wqfMGHL37T
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) July 26, 2019
Meta-Analysis: Very Early Mobilization After Stroke Does Not Improve Outcomes
29 Jul, 2019 | 20:32h | UTCVery Early Versus Delayed Mobilization After Stroke: Systematic Review and Meta-Analysis – Stroke (free PDF)
[Abstract Only] Meta-Analysis: Effect of Extending the Interval After Long‐course Chemoradiotherapy Before Surgery in Locally Advanced Rectal Cancer
27 Jul, 2019 | 20:03h | UTCMeta‐analysis of the effect of extending the interval after long‐course chemoradiotherapy before surgery in locally advanced rectal cancer – British Journal of Surgery (link to abstract – $ for full-text)
Source: EvidenceAlerts
Meta-analysis: Diagnosis of Elevated Intracranial Pressure in Critically Ill Adults
26 Jul, 2019 | 01:08h | UTCCommentary: Review examines methods for diagnosis of elevated ICP in critically ill – MedicalXpress (free)
Related Guidelines: Management of severe traumatic brain injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free) AND Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)
Related Reviews: Emergency Neurological Life Support: Intracranial Hypertension and Herniation – Neurocritical Care (free) AND Acute Management of Traumatic Brain Injury – Surgical Clinics of North America (free)
Related Commentary on Twitter
A question we often ask in the ED/ICU: Does this patient have increased ICP?
Our @bmj_latest study found that traditional physical exam and CT signs had poor accuracy for elevated ICP. If suspected, consider treatment & transfer for invasive monitoring.https://t.co/1Eb8PtYLFJ pic.twitter.com/bQFIgWnuur
— Shannon Fernando (@shanfernands) July 25, 2019
Meta-Analysis: Risk of Recurrent Thromboembolism after Discontinuation of Anticoagulant Treatment for First Unprovoked Venous Thromboembolism Event
26 Jul, 2019 | 01:06h | UTCCommentary: Long-Term Risk for Recurrent VTE Significant After Stopping Anticoagulation – NEJM Journal Watch (free)
“the risk of recurrent VTE was 10% in the first year after treatment, 16% at two years, 25% at five years, and 36% at 10 years, with 4% of recurrent VTE events resulting in death.”
Related Commentary on Twitter
Excited to share my first study published today in @bmj_latest on recurrence risk after stopping #anticoagulation for unprovoked #VTE. Big thanks to the MARVELOUS collaborators, @CIHR_IRSC for funding/support & @RodgerMarc for continued mentorship https://t.co/jnT86dRzHK#phdlife pic.twitter.com/SSVTYwkXth
— Faizan Khan (@FaizanK91) July 25, 2019
Meta-Analysis: Impact of Furosemide on Mortality and the Requirement for Renal Replacement Therapy in Acute Kidney Injury
26 Jul, 2019 | 00:45h | UTC
Systematic Review: Interventions for Preventing Obesity in Children
26 Jul, 2019 | 00:32h | UTCInterventions for preventing obesity in children – Cochrane Library (free)
Summary: Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? – Cochrane Library (free)
Systematic Review: Palliative Care for People with Dementia Living at Home
25 Jul, 2019 | 01:32h | UTC
Meta-Analysis: Plant-Based Dietary Patterns Linked to Lower Risk of Type 2 Diabetes
23 Jul, 2019 | 01:45h | UTCAssociation Between Plant-Based Dietary Patterns and Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Following a healthy plant-based diet may lower type 2 diabetes risk – JAMA Internal Medicine (free) Eating a plant-based diet might help prevent type 2 diabetes, study suggests – CNN (free) AND Healthy plant-based diets could reduce diabetes risk, study says – UPI (free) AND Expert reaction to study on the vegetarian diet and diabetes risk – Science Media Centre (free)
Meta-Analysis: Diagnostic Performance of PET or PET/CT Using 18F-FDG Labeled White Blood Cells in Infectious Diseases
23 Jul, 2019 | 01:22h | UTC
Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline
20 Jul, 2019 | 18:35h | UTCBuffered solutions versus 0.9% saline for resuscitation in critically ill adults and children – Cochrane Library (free)
Summary: Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children – Cochrane Library (free)
Related Meta-Analysis: Choice of Intravenous Crystalloid Fluid and Mortality in Critically Ill Adult Patients – Southern Medical Journal (link to abstract – $ for full-text)
Related Randomized Trials: Balanced Crystalloids vs Saline in Hospitalized Patients (free studies and commentary)
“The three ongoing studies once published and assessed may alter the conclusions of the review.”
Systematic Review: Incentives for Smoking Cessation
19 Jul, 2019 | 09:47h | UTCIncentives for smoking cessation – Cochrane Library (free)
Summaries: Can rewards help smokers to quit in the long term? – Cochrane Library (free) AND Featured Review: Incentives for smoking cessation – Cochrane Library (free)
Commentaries: Helping smokers quit: financial incentives work – The Conversation (free) AND NHS could save billions by offering cash reward to quit smoking – The Guardian (free)
Related Commentary on Twitter
Financial incentives for quitting smoking.
Read the latest Cochrane evidence from @CochraneTAG here: https://t.co/NzG2A2frcX pic.twitter.com/cqgBeKkeJf— Cochrane UK (@CochraneUK) July 18, 2019
Meta-Analysis: Preventable Patient Harm Across Medical Care Settings
18 Jul, 2019 | 10:54h | UTCEditorial: Preventable harm: getting the measure right (free)
Commentaries: One in 20 patients exposed to preventable harm in medical care – OnMedica (free) AND Half of All Patient Harms ‘Preventable’ – Medscape (free registration required)
Related Commentary on Twitter
Around one in 20 patients are affected by preventable harm in medical care, of which around 12% causes permanent disability or death, finds a study published by @bmj_latest today – take a look at the research https://t.co/oHxTBlh4s1 and linked editorial https://t.co/MBW6moT3pE pic.twitter.com/gxoL4V435w
— BMJ (@bmj_company) July 18, 2019
Meta-Analysis: Menstrual Cup Use, Leakage, Acceptability, Safety, and Availability
18 Jul, 2019 | 10:05h | UTCCommentaries: Inserting informed choice into global menstrual product use and provision – The Lancet Public Health (free) AND Menstrual Cups: Study Finds They’re Safe To Use — And People Like Them – NPR (free) AND Menstrual cups ‘as reliable as tampons’ – BBC (free) AND A Better Way to Manage Your Period? Try the Menstrual Cup, Scientists Say – The New York Times (free)
Meta-Analysis: Antiplatelet Therapy After Noncardioembolic Stroke
17 Jul, 2019 | 10:47h | UTCSource: EvidenceAlerts
“Results favor clopidogrel and aspirin/dipyridamole combination for long-term secondary prevention after noncardioembolic stroke or transient ischemic attack”.
Meta-Analysis: Risks of Stillbirth and Neonatal Death with Advancing Gestation at Term
16 Jul, 2019 | 09:46h | UTCCommentaries: New stillbirth risk figures help women’s decisions on timing delivery – Queen Mary University of London (free) AND Higher risk of stillbirth in longer pregnancies, study finds – PLOS (free) AND Expert reaction to study on longer pregnancies and risk of stillbirth – Science Media Centre (free)
Related Cochrane Review: Induction of Labor for Improving Birth Outcomes for Women at or Beyond Term (free)
Related Randomized Trials: Labor Induction vs. Expectant Management in Low-Risk Nulliparous Women (free) AND Induction of Labor at 41 Weeks vs. Expectant Management Until 42 Weeks (free)
Related WHO Recommendations: Induction of Labor at or Beyond Term (free)
[Abstract Only] Little Evidence for Nutritional Supplements to Improve Cardiovascular Outcomes
9 Jul, 2019 | 10:19h | UTCEffects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Little evidence supports nutritional supplements for protection against cardiovascular disease, death – ACP Internist (free) AND Nutritional supplements and diets not always protective, WVU research suggests – West Virginia University (free) AND Supplements and Diets for Heart Health Show Limited Proof of Benefit – The New York Times (10 articles per month are free)
Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
Meta-Analysis: Quadruple vs. Triple Combination Antiretroviral Therapies for Treatment-Naive People with HIV
9 Jul, 2019 | 09:41h | UTC
Cochrane Review: Pay for Performance for Hospitals
8 Jul, 2019 | 10:10h | UTCPay for performance for hospitals – Cochrane Library (free)
Summary: Pay for performance (payment or penalty methods to encourage hospitals to increase quality of care) – Cochrane Library (free)
Related Systematic Review: The Effects of Pay-for-Performance Programs on Health, Health Care Use, and Processes of Care: A Systematic Review – Annals of Internal Medicine (free)
See also: Impact of Financial Incentives on Early and Late Adopters among US Hospitals – The BMJ (free study and commentaries) AND Research: Pay-for-performance fails to perform (link to abstract and commentaries) AND Value-Based Purchasing: Time for Reboot or Time to Move On? – The JAMA Forum (free)
“We found either no difference at all or only a very slight effect for most P4P programs.”
Meta-Analysis: Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-eluting Stent
30 Jun, 2019 | 17:52h | UTCRelated Randomized Trials: Shorter Duration of Dual Antiplatelet Therapy May be an Option for Patients Undergoing Percutaneous Coronary Intervention (free studies and commentaries)
Meta-Analysis: Routine Urinary Screening Not Indicated Prior To Elective Total Joint Arthroplasty
30 Jun, 2019 | 17:14h | UTCIs Routine Urinary Screening Indicated Prior To Elective Total Joint Arthroplasty? A Systematic Review and Meta-Analysis – The Journal of Arthroplasty (free for a limited period)
Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake
27 Jun, 2019 | 09:05h | UTCRelated: Cochrane Review: Environmental Interventions to Reduce the Consumption of Sugar‐sweetened Beverages and Their Effects on Health (free study and commentaries) AND Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption (link to abstract and several resources on the subject) AND AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free statement and commentaries) AND Taxes on Sugar-Sweetened Beverages Associated with Reduced Consumption (link to abstract and commentaries)
Meta-Analysis: Incidence of New Onset Diabetes Mellitus Secondary to Acute Pancreatitis
26 Jun, 2019 | 01:07h | UTC