Systematic Reviews & Meta-analysis
M-A of randomized trials: proton pump inhibitors for gastro-esophageal reflux disease does not improve outcomes in patients with asthma.
13 Aug, 2021 | 08:53h | UTC
Systematic Review: Non-invasive ventilation used at night by people with COPD.
10 Aug, 2021 | 08:53h | UTCOriginal review: Chronic non‐invasive ventilation for chronic obstructive pulmonary disease – Cochrane Library
M-A: Effect of low glycemic index or load dietary patterns on glycemic control and cardiometabolic risk factors in diabetes.
8 Aug, 2021 | 23:42h | UTCCommentary: Low glycaemic diet shows meaningful improvements for people with diabetes – The British Medical Journal
Commentary on Twitter
New #BMJResearch finds that low glycaemic index/glycaemic load dietary patterns provide small important benefits for glycaemic control and other established cardiometabolic risk factors in adults with moderately controlled type 1 and type 2 diabeteshttps://t.co/EIMXUhICee
— The BMJ (@bmj_latest) August 7, 2021
M-A: Colchicine in patients with coronary artery disease – “colchicine reduces the risk of myocardial infarction and stroke, but has a higher rate of gastrointestinal upset with no influence on all‐cause mortality”.
8 Aug, 2021 | 23:40h | UTCRelated:
Review: Colchicine and the heart.
M-A: Colchicine administration for percutaneous coronary intervention
M-A: Efficacy and safety of low-dose colchicine in patients with coronary disease
Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease
Expert analysis: Efficacy and safety of colchicine in patients with chronic stable coronary disease
#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome
Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome
Endometrial scratching: what’s the latest evidence? – “we are uncertain whether endometrial injury has an effect on the probability of getting pregnant and having a baby”.
8 Aug, 2021 | 23:33h | UTCEndometrial scratching: what’s the latest evidence? – Cochrane Library
Original Review: Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination – Cochrane Library
Commentary on Twitter
Endometrial scratching is a procedure that is sometimes done with the aim of increasing the chance of pregnancy, but its use is debated. @SarahLensen of @CochraenCGF explains the latest Cochrane evidence in this new @CochraneUK blog: https://t.co/IFyYlXvS6v pic.twitter.com/PDEWRx4JPA
— Cochrane (@cochranecollab) August 6, 2021
Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks – “Given often-temporary improvements, unfavorable effects on dietary intake, and inadequate data demonstrating long-term safety, for most individuals, the risks of ketogenic diets may outweigh the benefits.”
4 Aug, 2021 | 08:53h | UTC
Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.
29 Jul, 2021 | 11:38h | UTCIvermectin for preventing and treating COVID‐19 – Cochrane Library
Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library
Commentary: Ivermectin treatment in humans for COVID-19 – Liverpool School of Tropical Medicine
Related:
Why was a major study on ivermectin for covid-19 just retracted?
RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.
RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
M-A of randomized trials: Conservative oxygen therapy for critically ill patients.
28 Jul, 2021 | 09:41h | UTC
M-A: Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications.
26 Jul, 2021 | 02:24h | UTC
Sodium-glucose cotransporter-2 inhibitors for type 2 diabetes mellitus in adults: An overview of 46 systematic reviews.
26 Jul, 2021 | 02:14h | UTC
M-A: Non-steroidal anti-inflammatory drugs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis.
16 Jul, 2021 | 10:28h | UTCNon-steroidal anti-inflammatory drugs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Akshintala et al – NSAIDs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-ERCP #pancreatitis: a systematic review and network meta-analysishttps://t.co/2Sh8WhqZRD#GITwitter #endoscopy #ERCP pic.twitter.com/nvAKXyPv13
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 30, 2021
Severe hearing loss in adults: finding out whether cochlear implants or hearing aids are better.
16 Jul, 2021 | 10:27h | UTC
Commentary on Twitter
Severe hearing loss in adults: finding out whether #CochlearImplants or #HearingAids are better: https://t.co/II0l1G74ny In a new @CochraneUK blog, Dr Adele Horobin from @NottmBRC discusses @COACH_trial, a new clinical trial seeking to find an answer. #LivingWithLTCs #HearingLoss pic.twitter.com/4Tx4jUC1KO
— The Cochrane Library (@CochraneLibrary) July 7, 2021
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
9 Jul, 2021 | 10:02h | UTCCommentary: New analysis finds muscle relaxant drugs to be largely ineffective for low back pain – News Medical
Related studies: M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain AND RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain AND M-A: Little benefit from antidepressants for low back pain AND Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis AND ACP/AAFP Guideline: Nonpharmacologic and pharmacologic management of acute pain from non–low back, musculoskeletal injuries in adults
Commentaries on Twitter
Muscle relaxants are largely ineffective for #lowback #pain. They might increase the risk of side effects.
Published today in @bmj_latest ⬇️
Proud to be a part of this excellent team led by @AidanCashin
Paper: https://t.co/4p7gd7PJIe pic.twitter.com/3CLvL7JUfI
— Hayley Leake (@HayleyLeake) July 8, 2021
This systematic review found very low certainty evidence that muscle relaxant drugs for the treatment of acute low back pain might provide a small and not clinically meaningful improvement in pain intensity at two weeks or less @Pain_NeuRa https://t.co/HGwN4Oekrq
— The BMJ (@bmj_latest) July 8, 2021
Systematic Review: Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.
9 Jul, 2021 | 09:50h | UTC
Systematic Review: Altered dietary salt intake for people with chronic kidney disease.
9 Jul, 2021 | 09:52h | UTCAltered dietary salt intake for people with chronic kidney disease – Cochrane Library
Summary: Altered dietary salt intake for adults with chronic kidney disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1410873135709278210
Systematic review: Prophylactic drug management for febrile seizures in children.
9 Jul, 2021 | 09:51h | UTCProphylactic drug management for febrile seizures in children – Cochrane Library
Summary: Prophylactic drug management for febrile seizures in children
M-A: Are antimicrobial stewardship interventions effective and safe in long-term care facilities?
8 Jul, 2021 | 08:52h | UTC
Systematic review: Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.
8 Jul, 2021 | 08:48h | UTC
M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.
8 Jul, 2021 | 08:50h | UTCContinuation of Antidepressants vs Sequential Psychological Interventions to Prevent Relapse in Depression: An Individual Participant Data Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Cognitive Therapy While Tapering Antidepressants May Be Alternative to Maintenance Medication – Psychiatric News Alert AND Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants – Mad in America
Commentary on Twitter
Sequential delivery of a psychological intervention while tapering antidepressants may be a potential alternative to long-term medication use in recurrent #depression, regardless of clinical risk factors @JosefienUMH, @Claudib123 https://t.co/UURRmv6qQO
— JAMA Psychiatry (@JAMAPsych) May 19, 2021
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
7 Jul, 2021 | 08:52h | UTC
M-A: The efficacy of systemic glucocorticosteroids for pain in rheumatoid arthritis.
6 Jul, 2021 | 09:54h | UTC
M-A: Pregnancy After Breast Cancer – “These results provide reassuring evidence on the safety of conceiving in BC survivors”.
6 Jul, 2021 | 09:55h | UTCPregnancy After Breast Cancer: A Systematic Review and Meta-Analysis – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Honored and excited to share our large #metanalysis presented at #SABCS20 now published in @ASCO_pubs #JCO providing solid and reassuring evidence on fetal and maternal safety of #pregnancy after prior #BreastCancer history@OncoAlert #SurvOnc #bcsm
Link: https://t.co/lgKQDeB2VS pic.twitter.com/rTpFKsrpMc— Matteo Lambertini, MD PhD (@matteolambe) July 1, 2021
Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations.
5 Jul, 2021 | 01:30h | UTCAntipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations – Drugs
M-A: Decision-making authority during Tele-ICU care reduces mortality and length of stay.
5 Jul, 2021 | 01:18h | UTCDecision-Making Authority During Tele-ICU Care Reduces Mortality and Length of Stay—A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Systematic review: Border controls, restricted entry, quarantine essential for curbing COVID-19 and future pandemics.
1 Jul, 2021 | 09:53h | UTCNews release: Border controls, restricted entry, quarantine essential for curbing COVID-19 and future pandemics – British Medical Journal
Commentary: Strategies ID’d Than Can Interrupt Spread of Infectious Disease – HealthDay