Systematic Reviews & Meta-analysis
M-A | Comparison of continuous versus intermittent enteral feeding in critically ill patients.
31 Oct, 2022 | 13:48h | UTC
M-A of RCT | Combination of ulinastatin and somatostatin evaluated in acute pancreatitis.
31 Oct, 2022 | 13:44h | UTC
M-A | Selective decontamination of the GI tract may reduce in-hospital mortality in ICU patients receiving mechanical ventilation.
27 Oct, 2022 | 12:39h | UTCAssociation Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Related Study: Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
M-A of RCT | Sleep deprivation is not effective as a treatment for major depressive episodes.
26 Oct, 2022 | 14:29h | UTC
M-A | Non-affective psychotic disorders and risk of dementia.
26 Oct, 2022 | 14:30h | UTCCommentaries:
Psychotic Disorders May Raise Risk for Later Dementia – HealthDay
M-A | Non-pharmacologic and pharmacologic treatments for anxiety in long-term care.
26 Oct, 2022 | 14:26h | UTC
Systematic Review | Point-of-care ultrasound in dyspnea, nontraumatic hypotension, and shock.
25 Oct, 2022 | 13:16h | UTC
Systematic Review | Mu‐opioid antagonists for opioid‐induced bowel dysfunction in palliative care and people with cancer.
25 Oct, 2022 | 13:13h | UTC
Systematic Review | Antipsychotic polypharmacy reduction vs. polypharmacy continuation for people with schizophrenia.
25 Oct, 2022 | 13:12h | UTCSummary: Reduction in the number of antipsychotics for people with schizophrenia – Cochrane Library
Related: Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations – Drugs
M-A of RCT | Analgesic efficacy and risk of low-to-medium dose intrathecal morphine in patients undergoing cardiac surgery.
25 Oct, 2022 | 13:10h | UTC
Conservative interventions for treating urinary incontinence in women: an overview of Cochrane systematic reviews.
24 Oct, 2022 | 14:13h | UTC
Systematic Review | Systemic corticosteroids for radicular and non‐radicular low back pain.
24 Oct, 2022 | 14:03h | UTCSystemic corticosteroids for radicular and non‐radicular low back pain – Cochrane Library
Systematic Review | Topical corticosteroids for dry eye.
24 Oct, 2022 | 14:02h | UTCTopical corticosteroids for dry eye – Cochrane Library
Systematic Review | TNF inhibitors for juvenile idiopathic arthritis‐associated uveitis.
21 Oct, 2022 | 12:55h | UTC
M-A | Safety and efficacy of tyrosine kinase inhibitors for the treatment of multiple sclerosis.
21 Oct, 2022 | 12:53h | UTC
M-A | The optimal timing for non-culprit PCI in patients with multivessel coronary artery disease.
21 Oct, 2022 | 12:52h | UTC
M-A | Scalp block for postoperative pain after craniotomy.
21 Oct, 2022 | 12:51h | UTC
M-A | Efficacy and safety of ketamine vs. electroconvulsive therapy among patients with major depressive episode.
20 Oct, 2022 | 12:30h | UTCEfficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
Commentary on Twitter
While #ElectroconvulsiveTherapy may be more efficacious than #ketamine for #depression severity in the acute phase, treatment options should be individualized and patient-centered. https://t.co/4poayVgsTG
— JAMA Psychiatry (@JAMAPsych) October 19, 2022
M-A of RCT | Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis.
20 Oct, 2022 | 12:25h | UTCCarvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis – Journal of Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
#Carvedilol
➡️non-selective #βblocker
✅associated with reduced risk of decompensating events
➡️improved survival in patients with #cirrhosis & #portalhypertensionRead it here👉https://t.co/yy8DIJBhfL#LiverTwitter pic.twitter.com/XxmrB7gff8
— Journal of Hepatology (@JHepatology) October 13, 2022
M-A | Interventions associated with reduced loneliness and social isolation in older adults.
19 Oct, 2022 | 14:22h | UTCRelated:
Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)
The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ
Social Isolation and Loneliness – World Health Organization
Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA
M-A | Endothelin receptor antagonists do not improve outcomes in idiopathic pulmonary fibrosis.
19 Oct, 2022 | 14:14h | UTC
M-A | Safety of sotagliflozin in diabetes mellitus type 1 and type 2.
19 Oct, 2022 | 14:12h | UTC
M-A | Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes.
19 Oct, 2022 | 14:11h | UTC
Systematic Review | Conservative vs. surgical management for femoro-acetabular impingement.
19 Oct, 2022 | 14:09h | UTCRelated:
Systematic Review | Reconstructive surgery for treating pressure ulcers – little evidence to guide recommendations.
18 Oct, 2022 | 12:46h | UTCReconstructive surgery for treating pressure ulcers – Cochrane Library