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Systematic Reviews & Meta-analysis

M-A | Risk of cardiovascular diseases associated with medications used in ADHD.

25 Nov, 2022 | 12:16h | UTC

Risk of Cardiovascular Diseases Associated With Medications Used in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: 

Paying Attention to Attention-Deficit/Hyperactivity Disorder Medications and Cardiovascular Risk – JAMA Network Open

Meta-Analysis Finds ADHD Drugs Not Linked To Risk Of Cardiovascular Disease – Reporter Health

 


SR | Surgical decompression for malignant cerebral edema after ischemic stroke.

24 Nov, 2022 | 13:25h | UTC

Surgical decompression for malignant cerebral oedema after ischaemic stroke – Cochrane Library

Summary: Surgical decompression for people with severe brain swelling after stroke – Cochrane Library

 


SR | Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery.

24 Nov, 2022 | 13:21h | UTC

Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery – Cochrane Library

 


SR | Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding.

24 Nov, 2022 | 13:24h | UTC

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding – Cochrane Library

Summary: Prothrombin complex concentrate in the treatment of bleeding that occurs with heart surgery – Cochrane Library

 


M-A | Optimal timing of anterior cruciate ligament reconstruction in patients with anterior cruciate ligament tear.

23 Nov, 2022 | 13:43h | UTC

Optimal Timing of Anterior Cruciate Ligament Reconstruction in Patients With Anterior Cruciate Ligament Tear: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


SR | Follicular flushing during oocyte retrieval in assisted reproductive techniques.

23 Nov, 2022 | 13:46h | UTC

Follicular flushing during oocyte retrieval in assisted reproductive techniques – Cochrane Library

 

Commentary on Twitter

 


SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.

22 Nov, 2022 | 13:39h | UTC

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease – Cochrane Library 

Summary: Blood pressure targets in people with cardiovascular disease – Cochrane Library 

 

Commentary on Twitter 

 


M-A | Balloon catheters vs. vaginal prostaglandins for labor induction.

22 Nov, 2022 | 13:35h | UTC

Balloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text) 

Commentary: Balloon labor induction safer for babies, researchers find – Monash University 

 

Commentary on Twitter (thread – click for more) 

 

 


M-A | Bioresorbable scaffolds vs. drug-eluting stents for patients with myocardial infarction.

22 Nov, 2022 | 13:29h | UTC

Bioresorbable scaffolds vs. drug-eluting stents for patients with myocardial infarction: A systematic review and meta-analysis of randomized clinical trials – Frontiers in Cardiovascular Medicine 

Related: M-A | Bioresorbable vascular scaffolds are inferior compared to conventional drug-eluting stents across time. 

 


M-A | Indocyanine green fluorescence in patients undergoing laparoscopic colorectal cancer surgery.

22 Nov, 2022 | 13:25h | UTC

Meta analysis of indocyanine green fluorescence in patients undergoing laparoscopic colorectal cancer surgery – Frontiers in Oncology 

 


SR | Early vitrectomy for exogenous endophthalmitis following surgery.

22 Nov, 2022 | 13:20h | UTC

Early vitrectomy for exogenous endophthalmitis following surgery – Cochrane Library 

Summary: Is the outcome of severe postoperative eye infection improved by early surgery to remove the vitreous gel? – Cochrane Library 

 


M-A | Cardiac and kidney adverse effects of HIF Prolyl-Hydroxylase inhibitors for anemia in patients with CKD not receiving dialysis.

22 Nov, 2022 | 13:22h | UTC

Cardiac and Kidney Adverse Effects of HIF Prolyl-Hydroxylase Inhibitors for Anemia in Patients With CKD Not Receiving Dialysis: A Systematic Review and Meta-analysis – American Journal of Kidney Diseases 

 


M-A | Effects of Tai Chi and Qigong on the mobility of stroke survivors.

22 Nov, 2022 | 13:10h | UTC

Effects of Tai Chi and Qigong on the mobility of stroke survivors: A systematic review and meta-analysis of randomized trials – PLOS One 

 


M-A | Burden of respiratory syncytial virus infection in older and high-risk adults in developed countries.

22 Nov, 2022 | 13:05h | UTC

Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries – European Respiratory Review 

 


SR | Exercise for acutely hospitalized older medical patients.

21 Nov, 2022 | 14:28h | UTC

Exercise for acutely hospitalised older medical patients – Cochrane Library 

Summary: Exercise for older patients during unplanned hospital stays – Cochrane Library 

 

Commentary on Twitter 

https://twitter.com/CochraneUK/status/1593169319881756672 

 


M-A | Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders.

21 Nov, 2022 | 14:11h | UTC

Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis – BJOG 

 

Commentary on Twitter 

https://twitter.com/BJOGTweets/status/1578676322095742977 

 


M-A | Cardiac and kidney adverse effects of HIF Prolyl-Hydroxylase inhibitors for anemia in patients with CKD not receiving dialysis.

21 Nov, 2022 | 14:03h | UTC

Cardiac and Kidney Adverse Effects of HIF Prolyl-Hydroxylase Inhibitors for Anemia in Patients With CKD Not Receiving Dialysis: A Systematic Review and Meta-analysis – American Journal of Kidney Diseases 

 


M-A | Prophylactic platelet transfusions vs. no prophylaxis in hospitalized patients with thrombocytopenia.

21 Nov, 2022 | 13:59h | UTC

Prophylactic platelet transfusions versus no prophylaxis in hospitalized patients with thrombocytopenia: A systematic review with meta-analysis – Transfusion 

 


M-A | Epidemiology of persistent postoperative opioid use after cardiac surgery.

21 Nov, 2022 | 13:36h | UTC

Epidemiology of persistent postoperative opioid use after cardiac surgery: a systematic review and meta-analysis – British Journal of Anaesthesia 

 


SR | There is insufficient evidence to recommend Ginkgo biloba for tinnitus.

18 Nov, 2022 | 13:19h | UTC

Ginkgo biloba for tinnitus – Cochrane Library

Summary: Ginkgo biloba herbal supplement for tinnitus – Cochrane Library

 


M-A | Effect of pharmacological treatment on outcomes of heart failure with preserved ejection fraction.

18 Nov, 2022 | 13:14h | UTC

Effect of pharmacological treatment on outcomes of heart failure with preserved ejection fraction: an updated systematic review and network meta-analysis of randomized controlled trials – Cardiovascular Diabetology

 


M-A | Long-term outcomes of turbinate surgery in patients with allergic rhinitis.

18 Nov, 2022 | 13:09h | UTC

Long-term Outcomes of Turbinate Surgery in Patients With Allergic Rhinitis: A Systematic Review and Meta-analysis  – JAMA Otolaryngology—Head & Neck Surgery (free for a limited period) 

 


SR | Mosquito aquatic habitat modification and manipulation interventions to control malaria.

17 Nov, 2022 | 12:06h | UTC

Mosquito aquatic habitat modification and manipulation interventions to control malaria – Cochrane Library

 


M-A | A short course of antibiotics is noninferior to long-course therapy in children with nonsevere pneumonia.

16 Nov, 2022 | 13:43h | UTC

Short-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)

Commentary: Review: Shorter antibiotic course sufficient for kids with pneumonia – CIDRAP

Related:

RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).

RCT: In children with community-acquired pneumonia, outpatient antibiotic therapy for 5 days resulted in similar clinical response rates compared to a standard 10-day strategy.

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia

RCT: Among children with community-acquired pneumonia discharged within 48 hours from the ED or hospital, lower-dose outpatient oral amoxicillin was noninferior to a higher dose, and a 3-day duration course was noninferior to 7 days.

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review – short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

 


SR | Immunostimulants vs. placebo for preventing exacerbations in adults with chronic bronchitis or COPD.

16 Nov, 2022 | 13:34h | UTC

Immunostimulants versus placebo for preventing exacerbations in adults with chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library

Summary: Is taking an immunostimulant on top of standard medications beneficial for people with chronic obstructive pulmonary disease, chronic bronchitis, or both? – Cochrane Library

 


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