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Radiation Oncology

Non-inferiority randomized trial showed radiotherapy can be safely omitted in many children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma.

10 Dec, 2021 | 10:04h | UTC

Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded, multinational, non-inferiority, randomised controlled trial – The Lancet Oncology

 

Review | Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification.

5 Dec, 2021 | 23:40h | UTC

Past, Present, and Future of Radiation-Induced Cardiotoxicity: Refinements in Targeting, Surveillance, and Risk Stratification – JACC: CardioOncology

Video: Radiation Therapy and Cardiovascular Disease | JACC: CardioOncology Author Discussion

Related:

Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

Radiation‐induced cardiovascular disease: review of an underrecognized pathology.

Short review: How to diagnose and manage radiation therapy cardiotoxicity

Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer

 

Advances in Breast Cancer Radiotherapy: Implications for Current and Future Practice.

30 Nov, 2021 | 09:55h | UTC

Advances in Breast Cancer Radiotherapy: Implications for Current and Future Practice – JCO Oncology Practice

 

Commentary on Twitter

 

Long-term results of RCT: Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for patients with locally advanced rectal cancer.

19 Nov, 2021 | 10:15h | UTC

Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer: Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Author Interview: Chemoradiotherapy Plus Induction or Consolidation Chemotherapy for Locally Advanced Rectal Cancer – JAMA Oncology

 

Commentary on Twitter

 

M-A: Comparison of outcomes between neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy in patients with locally advanced esophageal cancer.

7 Nov, 2021 | 20:07h | UTC

Comparison of outcomes between neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy in patients with locally advanced esophageal cancer: A network meta-analysis – EClinicalMedicine

 

RCT: Elective internal mammary node irradiation does not increase disease-free survival or overall survival in most women with node-positive breast cancer.

27 Oct, 2021 | 01:28h | UTC

Effect of Elective Internal Mammary Node Irradiation on Disease-Free Survival in Women With Node-Positive Breast Cancer: A Randomized Phase 3 Clinical Trial – JAMA Oncology (free for a limited period)

Commentary: No Survival Benefit for Internal Mammary Node Irradiation in Breast Cancer — Women with medially or centrally located tumors may be candidates, however, says researcher – MedPage Today (free registration required)

 

Commentary on Twitter

 

Radiotherapy: Clinical pearls for primary care.

22 Oct, 2021 | 10:12h | UTC

Radiotherapy: Clinical pearls for primary care – Canadian Family Physician

 

Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

1 Oct, 2021 | 10:21h | UTC

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study – JACC: CardioOncology

Commentaries:

Left Breast Radiation Therapy Doubles CV Disease Risk vs. Right Breast Radiation Therapy in Young Women – American College of Cardiology

CAD in Young Women After Radiation Therapy for Breast Cancer – American College of Cardiology

 

Commentary on Twitter

 

Guidelines for the surveillance and survivorship care of patients after curative treatment of colon and rectal cancer.

16 Sep, 2021 | 09:52h | UTC

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surveillance and Survivorship Care of Patients After Curative Treatment of Colon and Rectal Cancer – Diseases of the Colon & Rectum

Related: Study: Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy

 

Commentary on Twitter

 

Systematic Review: Partial breast irradiation versus whole breast radiotherapy for early breast cancer.

15 Sep, 2021 | 08:46h | UTC

Partial breast irradiation versus whole breast radiotherapy for early breast cancer – Cochrane Library

 

Commentary on Twitter

 

Long-term report of study evaluating radiation following surgical excision for good-risk ductal carcinoma in situ.

14 Sep, 2021 | 08:44h | UTC

Randomized Phase III Trial Evaluating Radiation Following Surgical Excision for Good-Risk Ductal Carcinoma In Situ: Long-Term Report From NRG Oncology/RTOG 9804 – Journal of Clinical Oncology

 

Commentary on Twitter

 

Radiation‐induced cardiovascular disease: review of an underrecognized pathology.

9 Sep, 2021 | 08:54h | UTC

Radiation‐Induced Cardiovascular Disease: Review of an Underrecognized Pathology – Journal of the American Heart Association

 

Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis treatment and follow-up of patients with localized colon cancer.

26 Aug, 2021 | 08:33h | UTC

Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis treatment and follow-up of patients with localised colon cancer – Annals of Oncology

 

ASCO Guideline: Salivary gland hypofunction and/or xerostomia induced by nonsurgical cancer therapies.

19 Aug, 2021 | 08:50h | UTC

Salivary Gland Hypofunction and/or Xerostomia Induced by Nonsurgical Cancer Therapies: ISOO/MASCC/ASCO Guideline – Journal of Clinical Oncology

 

Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer – “This trial provides the first clinical evidence that sparing the hippocampus during PCI in patients with SCLC better preserves cognitive function”.

13 Aug, 2021 | 08:54h | UTC

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study – Journal of Clinical Oncology

 

RCT: Efficacy of concurrent chemoradiotherapy with S-1 vs. radiotherapy alone for older patients with esophageal cancer.

8 Aug, 2021 | 23:35h | UTC

Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer: A Multicenter Randomized Phase 3 Clinical Trial – JAMA Oncology (free for a limited period)

Editorial: Primary Chemoradiotherapy for Older Patients With Esophageal Cancer (free for a limited period)

Commentary: Concurrent CRT Effective for Esophageal Cancer in Older Patients — Overall survival at 2 years significantly better versus radiotherapy alone – MedPage Today (free registration required)

 

Commentary on Twitter

 

ASTRO Guideline: Radiation therapy for treatment of soft tissue sarcoma in adults.

29 Jul, 2021 | 10:54h | UTC

Radiation Therapy for Treatment of Soft Tissue Sarcoma in Adults: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

News release: Astro Issues Clinical Guideline on Radiation Therapy for Soft Tissue Sarcoma in Adults

 

ESMO Guidelines: Soft tissue and visceral sarcomas.

29 Jul, 2021 | 10:53h | UTC

Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Radiation therapy-associated toxicity: Etiology, management, and prevention.

15 Jul, 2021 | 09:13h | UTC

Radiation therapy-associated toxicity: Etiology, management, and prevention – CA: A Cancer Journal for Clinicians

 

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

1 Jul, 2021 | 09:44h | UTC

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Commentary on Twitter

 

Randomized trial long-term results confirm the benefits of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer

20 May, 2021 | 08:16h | UTC

Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial – Journal of Clinical Oncology

 

Commentaries on Twitter

 

RCT: Inclusion of 18F-fluciclovine-PET/CT imaging to guide postprostatectomy salvage radiotherapy in patients with prostate cancer may improve survival free from biochemical recurrence or persistence.

10 May, 2021 | 00:46h | UTC

18F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial – The Lancet (link to abstract – $ for full-text)

 

Population-based cohort study suggests increased survival after breast conservation surgery + radiotherapy compared to mastectomy with or without radiotherapy in women with breast cancer.

10 May, 2021 | 00:42h | UTC

Survival After Breast Conservation vs Mastectomy Adjusted for Comorbidity and Socioeconomic Status: A Swedish National 6-Year Follow-up of 48 986 Women – JAMA Surgery

Commentary: Breast-Conserving Surgery+RT Yields Significant Survival Benefits For Early-Stage Breast Cancer – Physician’s Weekly

 

Commentary on Twitter

 

Review: Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer

30 Apr, 2021 | 08:31h | UTC

Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer – JCO Oncology Practice

 

M-A: Chemotherapy and radiotherapy in locally advanced head and neck cancer

15 Apr, 2021 | 06:29h | UTC

Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis – The Lancet Oncology

 

Commentary on Twitter

 

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