Psychiatry
The effect of multiple adverse childhood experiences on health
10 Aug, 2017 | 19:39h | UTCThe effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis – The Lancet Public Health (free) (RT @equitylist see Tweet)
Invited commentary: Inequality and intergenerational transmission of complex adversity (free)
Editorial: Our greatest untapped resource (free)
What do hypnotics cost hospitals and healthcare?
10 Aug, 2017 | 17:16h | UTCWhat do hypnotics cost hospitals and healthcare? – F1000 Research (free)
Source: Hospital Medicine Virtual Journal Club
“A best estimate is that U.S. costs of hypnotic harms to healthcare systems are on the order of $55 billion, but conceivably might be as low as $10 billion or as high as $100 billion”.
Effect of marijuana use on cardiovascular and cerebrovascular mortality
10 Aug, 2017 | 17:13h | UTCCommentaries: Marijuana associated with three-fold risk of death from hypertension – European Society of Cardiology, via Science Daily (free) AND Marijuana use holds three-fold blood pressure death risk: study – Reuters (free) AND Marijuana Use Tied to Death from Hypertension, Study Suggests – Physician’s First Watch (free) AND Marijuana ‘may be worse than cigarettes for cardiovascular health’ – Medical News Today (free)
Free Online Course: Positive Psychiatry and Mental Health
7 Aug, 2017 | 00:58h | UTCStarts Today! Free Online Course: Positive Psychiatry and Mental Health – University of Sidney and Coursera
Have Smartphones Destroyed a Generation?
4 Aug, 2017 | 17:54h | UTCHave Smartphones Destroyed a Generation? – The Atlantic (free)
Long read… very interesting.
Mental Health Disorders in Adolescents
3 Aug, 2017 | 13:38h | UTCCommittee Opinion No. 705: Mental Health Disorders in Adolescents – Obstetrics & Gynecology (free)
Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes
3 Aug, 2017 | 13:37h | UTC
Internet Searches for Suicide Following the Release of “13 Reasons Why”
1 Aug, 2017 | 22:36h | UTCInternet Searches for Suicide Following the Release of “13 Reasons Why” – JAMA Internal Medicine (free)
Editorial: A Call for Social Responsibility and Suicide Risk Screening, Prevention, and Early Intervention Following the Release of the Netflix Series “13 Reasons Why” (free)
Commentaries: ‘13 Reasons Why’ might have triggered suicide searches online – STAT News (free) AND Is ’13 Reasons Why’ Helping Kids Kill Themselves? – MedPage Today (free registration required) AND Google Searches on Suicide Surge After ’13 Reasons Why’ Release: Study – Newsweek (free) Suicide-Related Internet Searches Elevated After Debut of “13 Reasons Why” – Physician’s First Watch (free)
Sugar intake from sweet food and beverages, common mental disorder and depression
28 Jul, 2017 | 16:09h | UTCCommentaries: Too much sugar could increase depression risk in men, study suggests – The Guardian (free) AND High sugar diets linked to heightened depression risk in men – The Independent (free)
Association does not imply causation, but this observational study suggests sugar intake has adverse effects on long-term psychological health.
Antipsychotics in Acute Schizophrenia
27 Jul, 2017 | 17:34h | UTCSixty Years of Placebo-Controlled Antipsychotic Drug Trials in Acute Schizophrenia: Systematic Review, Bayesian Meta-Analysis, and Meta-Regression of Efficacy Predictors – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Antipsychotic Response Rates Through the Prism of 60 Years – Psychiatric Times (free)
Source: EvidenceAlerts (free resource to find articles of interest)
Twice as many patients improved with antipsychotics as with placebo, confirming the benefits of antipsychotic drugs for the treatment of schizophrenia.
Abuse of online games
25 Jul, 2017 | 00:59h | UTCSee related articles and guidelines on recommended screen time for kids in our April 10th issue (see #6)
“Abuse of online games does not have to rot the brain to be a disorder worth investigating” (RT @NatureNews see Tweet)
Psychosis relapse, medication non-adherence, and cannabis
25 Jul, 2017 | 00:15h | UTCCommentaries: Psychosis relapse, medication non-adherence, and cannabis – The Lancet Psychiatry (free) AND Cannabis Use Directly Linked to Psychosis Relapse – Medscape (free registration required)
Why are doctors plagued by depression and suicide?
25 Jul, 2017 | 00:09h | UTCWhy are doctors plagued by depression and suicide? A crisis comes into focus – STAT News (free)
Related: Protecting interns and other physicians from depression and suicide – STAT News (free)
Study: Alcohol Misuse Prevention Programme
23 Jul, 2017 | 19:47h | UTCIntervention delivered in Northern Irish and Scottish schools reduces binge drinking – NIHR Signal (free)
Original study: Steps Towards Alcohol Misuse Prevention Programme (STAMPP): a school- and community-based cluster randomised controlled trial – Public Health Research (free)
Report: Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use
23 Jul, 2017 | 16:32h | UTCNews Release: National Strategy to Reduce Opioid Epidemic, an Urgent Public Health Priority, Presented in New Report (free)
Commentary: National Academies Recommend Steps to Address Opioid Crisis – Physician’s First Watch (free)
Three psychological therapies are effective for adolescent depression
22 Jul, 2017 | 22:30h | UTCThree psychological therapies are effective for adolescent depression – NIHR Signal (free)
Original article: Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial – The Lancet Psychiatry (free) AND Commentaries: From efficacy to pragmatic trials: does the dodo bird verdict apply? – The Lancet Psychiatry? (free) AND New ways to treat depression in teenagers – The Conversation (free)
“Three psychological therapies equally effective for adolescent depression” (RT @NIHR_DC see Tweet)
Simultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression
22 Jul, 2017 | 19:19h | UTCSimultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression, United States, 2001-2014 – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Benzodiazepines With Antidepressants May Spark Long-term Use – Medscape (free registration required) AND Antidepressants plus benzos: Is it worth the risk? – Pharmacy News (free)
In this large cohort, patients who were treated with benzodiazepine associated with antidepressants in the beginning of the treatment for depression didn’t seem to have a clinical benefit, and 12.3% of patients who began treatment with both agents had long-term (6-month) benzodiazepine use. Due to the observational nature of this study, it may be that these patients had more severe depression, but caution is advised nonetheless.
Risk of Irritability With Psychostimulant Treatment in Children With ADHD
22 Jul, 2017 | 18:08h | UTCRisk of Irritability With Psychostimulant Treatment in Children With ADHD: A Meta-Analysis – Journal of Clinical Psychiatry (link to abstract – $ for full-text)
“MPH decreased risk of irritability vs PLA (RR=0.89), whereas amphetamines increased the risk (RR=2.90)” (RT @psychopharmacol see Tweet)
The Regulation of Alcohol Marketing: From Research to Public Health Policy
22 Jul, 2017 | 16:25h | UTCSupplement: The Regulation of Alcohol Marketing: From Research to Public Health Policy – Addiction (free articles)
Commentaries: Evidence Growing of Link Between Youth Exposure to Alcohol Marketing and Youth Drinking – Johns Hopkins Bloomberg School of Public Health, via NewsWise (free) AND Alcohol advertising is aggressive and linked to youth drinking, research finds – The Guardian (free) (RT @pash22 see Tweet)
Helping Those Who Hoard
22 Jul, 2017 | 16:38h | UTCHelping Those Who Hoard – The New York Times (10 articles per month are free)
Mental health should be a priority for WHO’s new director-general
22 Jul, 2017 | 14:15h | UTCOpinion: Mental health should be a priority for WHO’s new director-general – STAT News (free)
Antidepressants during pregnancy and autism in offspring
21 Jul, 2017 | 17:49h | UTCAntidepressants during pregnancy and autism in offspring: population based cohort study – The BMJ (free)
Editorial: Prenatal antidepressant use and risk of autism (free)
Commentaries: Antidepressants and pregnancy: study didn’t find they actually cause autism – The Conversation (free) AND Antidepressant use in pregnancy linked to autism in children – OnMedica (free) AND Study finds slight autism risk link to antidepressants in pregnancy – Reuters (free)
Patient Outcomes in Dose Reduction or Discontinuation of Long-Term Opioid Therapy
20 Jul, 2017 | 00:04h | UTCPatient Outcomes in Dose Reduction or Discontinuation of Long-Term Opioid Therapy: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Tapering long-term opioid therapy may improve outcomes in chronic pain, review finds – ACP Internist (free) AND Opioid Reduction Therapy Offers Some Benefits to Patients with Chronic Pain – Physician’s First Watch (free) AND How tapering off opioids can help people with chronic pain – CNN (free)
“Opioid tapering:
– less pain: 8 of 8 studies
– Improved function: 5 of 5 studies
– Improved QOL: 3 of 3 studies” (RT @DavidJuurlink see Tweet)
Efficacy of Tramadol Extended-Release for Opioid Withdrawal
13 Jul, 2017 | 20:52h | UTCCommentaries: Extended-Release Tramadol May Ease Opioid Withdrawal Symptoms – Physician’s First Watch (free)
Antidepressant Switching vs Augmentation in Resistent Depression?
12 Jul, 2017 | 15:24h | UTCEffect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Study Compares Switching Meds vs an Additional Med for Patients Unresponsive to an Antidepressant – The Jama Network (free) AND For Treatment-Resistant Depression, Add an Antipsychotic or Switch Antidepressants? – Physician’s First Watch (free)
Augmentation with aripiprazole led to a modestly increased likelihood of remission, but with more adverse effects. “Given the small effect size and adverse effects associated with aripiprazole, further analysis including cost-effectiveness is needed to understand the net utility of this approach”.