Psychiatry
Systematic Review | Organizational changes likely decrease physical restraint usage in long-term care
31 Jul, 2023 | 13:53h | UTC
Phase 2 Trial | Oral orexin receptor 2 agonist shows promise in narcolepsy type 1, but raises hepatotoxic concerns
28 Jul, 2023 | 14:09h | UTCOral Orexin Receptor 2 Agonist in Narcolepsy Type 1 – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In a randomized trial involving patients with narcolepsy, an oral orexin receptor 2 agonist reduced sleepiness and cataplexy but had liver toxic effects. Read the full trial results: https://t.co/Go7lmQTu62
— NEJM (@NEJM) July 26, 2023
RCT | Zuranolone, a potential rapid-acting oral treatment for severe postpartum depression
27 Jul, 2023 | 13:00h | UTCZuranolone for the Treatment of Postpartum Depression – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Postpartum Depression Pill Zuralonone Shows Promise in Women With Severe Symptoms – Psychiatric News Alert
Related: RCT | Zuranolone outperforms placebo in major depressive disorder treatment
Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness
26 Jul, 2023 | 13:28h | UTC
Systematic Review | Existing research on post-stroke depression interventions lacks conclusive results
25 Jul, 2023 | 13:37h | UTC
Cohort Study | Increased risk of depression and suicide among people with HIV, especially in the first two years post-diagnosis
24 Jul, 2023 | 13:01h | UTC
Commentary on Twitter
Risk of Depression in People With HIV: A nationwide population-based matched cohort study
✅ Just Accepted
? Freely Availablehttps://t.co/nyrzPqRRqw— Clinical Infectious Diseases (@CIDJournal) July 22, 2023
RCT | Online emotion regulation therapy yields significant reduction in adolescent self-injury
24 Jul, 2023 | 12:39h | UTCSee also: Visual Abstract
News Release: Internet-based therapy effective against self-harm in adolescents – Karolinska Institutes
Cohort Study | Bipolar disorder associated with a 6-fold higher mortality risk from external causes
21 Jul, 2023 | 13:29h | UTCNews Release: Bipolar disorder linked to 6-fold heightened risk of early death from external causes – BMJ Newsroom
M-A | Adverse effects of antipsychotics on sleep in patients with schizophrenia
18 Jul, 2023 | 13:45h | UTC
RCT | Placebo equally effective as cognitive-behavioral therapy and aripiprazole in preventing psychosis transition
18 Jul, 2023 | 13:37h | UTCPrevention of First-Episode Psychosis in People at Clinical High Risk: A Randomized Controlled, Multicentre Trial Comparing Cognitive-Behavioral Therapy and Clinical Management Plus Low-Dose Aripiprazole or Placebo (PREVENT) – Schizophrenia Bulletin (link to abstract – $ for full-text)
Meta-Analysis | Nearly 6% of first-episode psychosis patients exhibit clinically relevant MRI abnormalities
17 Jul, 2023 | 13:32h | UTCNews Release: Routine brain scanning may improve clinical care for people with psychosis – University of Oxford
Cohort Study | Mental disorders linked to increased cardiovascular events in young patients
17 Jul, 2023 | 13:20h | UTCIncreased cardiovascular events in young patients with mental disorders: a nationwide cohort study – European Journal of Preventive Cardiology (free for a limited period)
News Release: Under 40s with mental health problems have elevated risks of heart attack and stroke – European Society of Cardiology
RCT | 4-week course of subcutaneous ketamine shows efficacy in treatment-resistant depression
17 Jul, 2023 | 13:17h | UTCNews Release: Ketamine effective for treatment-resistant depression: Clinical trial – University of New South Wales
Related:
RCT | Ketamine non-Inferiority to ECT for nonpsychotic resistant depression
Clinical practice guideline for deprescribing opioid analgesics
12 Jul, 2023 | 13:58h | UTCRelated:
RCT | Opioids not more effective than placebo for acute low back and neck pain
RCT | A deprescribing intervention reduced medication burden among older adults in post-acute care
Deprescribing proton pump inhibitors – Australian Journal of General Practice
Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports
Deprescribing in Palliative Cancer Care – Life
Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan – Lown Institute
Common ED Medication Errors: Polypharmacy – emDocs
Current and future perspectives on the management of polypharmacy – BMC Family Practice
Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international
Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety
USPSTF | Routine depression screening recommended for adults including pregnant and postpartum women
11 Jul, 2023 | 14:09h | UTCEvidence Report: Depression and Suicide Risk Screening: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Patient Page: Screening for Depression and Suicide Risk in Adults – JAMA
Editorials:
Reframing the Key Questions Regarding Screening for Suicide Risk – JAMA
Suicidality Screening Guidelines Highlight the Need for Intervention Studies – JAMA Network Open
Related:
Health advisory on social media use in adolescence
11 Jul, 2023 | 14:03h | UTCHealth advisory on social media use in adolescence – American Psychological Association
News Release: APA panel issues recommendations for adolescent social media use – American Psychological Association
New tool OxSATS may accurately predict 12-month suicide risk after self-harm
11 Jul, 2023 | 13:39h | UTCNews Release: Newly developed scoring system can correctly predict suicide risk after self harm – BMJ Newsroom
M-A | Efficacy of varenicline versus bupropion for smoking cessation
10 Jul, 2023 | 13:23h | UTC
Podcast | Updates in addiction medicine
10 Jul, 2023 | 13:17h | UTC#401 Updates in Addiction Medicine – SGIM 2023 – The Curbsiders
RCT | Transcranial direct current stimulation fails to outperform sham in major depressive disorder treatment
5 Jul, 2023 | 01:12h | UTCTranscranial direct current stimulation as an additional treatment to selective serotonin reuptake inhibitors in adults with major depressive disorder in Germany (DepressionDC): a triple-blind, randomised, sham-controlled, multicentre trial – The Lancet (link to abstract – $ for full-text)
USPSTF Recommendations | Screen for anxiety disorders in adults, including pregnant and postpartum women
30 Jun, 2023 | 15:03h | UTCEditorial: Are There Reasons to Fear Anxiety Screening? – JAMA
Evidence Report: Anxiety Screening: Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Patient Page: Screening for Anxiety Disorders in Adults – JAMA
Author Interview: USPSTF Recommendations: Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults – JAMA
M-A | Comparing the efficacy of different types of exercise for the treatment and prevention of depression in youths
30 Jun, 2023 | 14:40h | UTC
Consensus Paper | Care for older forensic mental health patients
29 Jun, 2023 | 13:54h | UTCCare for older forensic mental health patients: A consensus guidance document – European Psychiatry
Perspective | Psychedelic treatments for mental health conditions pose challenges for informed consent
28 Jun, 2023 | 13:17h | UTC
M-A | Lifetime burden of psychological symptoms, disorders, and suicide due to cancer in childhood, adolescent, and young adult years
26 Jun, 2023 | 00:39h | UTCLifetime Burden of Psychological Symptoms, Disorders, and Suicide Due to Cancer in Childhood, Adolescent, and Young Adult Years: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: Poor Mental Health Among Survivors of Childhood Cancer—Risk Factors and a Call for Intervention – JAMA Pediatrics (free for a limited period)