Psychiatry
RCT: Comparison of intranasal vs. intramuscular naloxone in opioid overdoses managed by ambulance staff.
14 Apr, 2022 | 08:23h | UTC
Economic evaluation: cost-effectiveness of installing barriers at bridge and cliff sites for suicide prevention in Australia.
14 Apr, 2022 | 08:01h | UTCInvited Commentary: Rethinking Suicide Prevention as a Public Health Issue – JAMA Network Open
Commentary on Twitter
This economic evaluation found that barriers installed at multiple bridge sites – but not cliffs – in Australia were a cost-effective measure in reducing suicide rates at bridges. https://t.co/5D0MIzLZ1Y
— JAMA Network Open (@JAMANetworkOpen) April 5, 2022
USPSTF draft statement recommends screening for anxiety and depression in children and adolescents ages 8 to 18 years.
13 Apr, 2022 | 11:05h | UTCDraft Statements:
Screening for Anxiety in Children and Adolescents – US Preventive Services Task Force
Commentary:
USPSTF Recommends Anxiety, Depression Screening for Children – HealthDay
The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019.
13 Apr, 2022 | 11:03h | UTCInvited Commentary: The burden of young people’s mental health conditions in Europe: No cause for complacency – The Lancet Regional Health Europe
Related:
Commentary on Twitter
See our new @IHME_UW analysis from on the #burden of #mentaldisorders, substance use disorders & self-harm among young people in Europe. In 2019 there were 16,983 MDs cases/100.000. In last 30 yrs YLD for eating disorders & drug use disorders increased. https://t.co/hMbHDlPuur pic.twitter.com/Rt4Iq4tpAA
— Maciej Banach (@maciejbanach) April 2, 2022
(Article and images under a CC BY 4.0 license)
RCT: Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis.
13 Apr, 2022 | 10:31h | UTCNews Release: Breakthrough success in provision of automated psychological therapy using virtual reality – University of Oxford
Commentary from the author on Twitter
gameChange results are out! Six sessions of automated VR therapy reduced agoraphobic avoidance and distress for patients with psychosis. People who were mainly housebound had large benefits maintained at 6mths. @OxPsychiatry @NIHRresearch @TheLancetPsych https://t.co/VE9oxsa5cf pic.twitter.com/KAvuLqHtiI
— Daniel Freeman (@ProfDFreeman) April 6, 2022
Systematic Review: Control interventions in randomized trials among people with mental health disorders.
13 Apr, 2022 | 09:38h | UTCFeatured review: Control interventions in randomized trials among people with mental health disorders
Perspective: Supervised consumption sites—a tool for reducing risk of overdose deaths and infectious diseases in people who use illicit drugs.
11 Apr, 2022 | 00:59h | UTCSupervised Consumption Sites—A Tool for Reducing Risk of Overdose Deaths and Infectious Diseases in People Who Use Illicit Drugs – JAMA (free for a limited period)
Commentary on Twitter
NYC last fall opened the first 2 US supervised consumption sites, where people can use illicit drugs under the watchful eye of staff trained to reverse overdoses, but such centers have operated elsewhere—sometimes under the radar—for decades. https://t.co/mS7wLZd164
— JAMA (@JAMA_current) April 6, 2022
Autistic people are six times more likely to attempt suicide – poor mental health support may be to blame.
8 Apr, 2022 | 10:02h | UTC
Cohort Study: Comparison of rates of Type 2 Diabetes in adults and children treated with anticonvulsant mood stabilizers.
7 Apr, 2022 | 08:32h | UTC
Commentary on Twitter
This cohort study found that the choice of which anticonvulsant mood stabilizer to initiate may have meaningful reductions in type 2 diabetes incidence; valproate was associated with the highest risk and lamotrigine the lowest. https://t.co/pyME0G25wt
— JAMA Network Open (@JAMANetworkOpen) April 6, 2022
M-A: Immediate and sustained outcomes and moderators associated with metacognitive training for psychosis.
7 Apr, 2022 | 08:10h | UTC
Global, regional, and national trends in opioid analgesic consumption from 2015 to 2019.
6 Apr, 2022 | 10:49h | UTCNews Release: Global disparities persist in opioid painkiller access – University College London
Invited Commentary: Closing the global pain divide: balancing access and excess – The Lancet Public Health
Commentary on Twitter (article and images under a Creative Commons Attribution (CC BY 4.0 license)
Just Out @TheLancetPH 🚨
Global #opioids consumption increased from 2015 to 2019‼️#Disparities in opioid💊consumption remained, indicating potential inadequate access to essential pain relief in countries with low consumption🌐https://t.co/bkcdgLy3ZP pic.twitter.com/RUGl1gbiTw— Gil Morgan, MD (@weoncologists) April 1, 2022
Opinion | Medicinal cannabis for chronic pain: the Bermuda triangle of low-quality studies, countless meta-analyses and conflicting recommendations.
5 Apr, 2022 | 08:52h | UTCRelated:
M-A: Birth outcomes of neonates exposed to marijuana in utero.
Cannabis-related allergies: an international overview and consensus recommendations.
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Review: Considerations for cannabinoids in perioperative care by anesthesiologists.
Review: Cannabis-based Medicines and the Perioperative Physician
Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know
WHO’s training for caregivers of children with autism goes online.
4 Apr, 2022 | 00:59h | UTCNews Release: WHO’s training for caregivers of children with autism goes online – World Health Organization
Online Course: WHO eLearning Caregiver Skills Training for Families of Children with Developmental Delays or Disabilities – OpenWHO
RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.
1 Apr, 2022 | 10:07h | UTCCommentaries:
Study raises questions about risks of using medical marijuana for mood and anxiety disorders – CNN
Medical Marijuana Rx Ups Odds for Overuse, With No Benefit to Health: Study – HealthDay
Commentary on Twitter
RCT finds medical marijuana cards (MMC) are linked to an increase in cannabis use disorder, with no improvements in pain, depression, and anxiety for adults using medical marijuana but improvements in sleep. https://t.co/0gtGFi1RQ9
— JAMA Network Open (@JAMANetworkOpen) March 18, 2022
RCT: Amisulpride and olanzapine combination treatment versus each monotherapy in acutely ill patients with schizophrenia.
1 Apr, 2022 | 09:47h | UTCAmisulpride and olanzapine combination treatment versus each monotherapy in acutely ill patients with schizophrenia in Germany (COMBINE): a double-blind randomised controlled trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
RCT: At 8 weeks, PANSS total score improved more with amisulpride + olanzapine (−29·6) than with olanzapine + placebo (−24·1, p=0·049, d=0·396), but not vs. amisulpride + placebo (−25·2, p=0·095, d=0·29) in acutely ill patients with schizophrenia https://t.co/Se75PJ3a0N
— P𝘧OL (@psychopharmacol) March 18, 2022
M-A: Psychological interventions for chronic, non-specific low back pain.
31 Mar, 2022 | 08:20h | UTCNews Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal
Cohort Study: Mortality associated with mental disorders and comorbid general medical conditions.
31 Mar, 2022 | 08:15h | UTCMortality Associated With Mental Disorders and Comorbid General Medical Conditions – JAMA Psychiatry
Commentary: People with Mental Disorders, General Comorbid Conditions Have 11-Year Reduced Life Expectancy – HCP Live
Systematic Review: The global gap in treatment coverage for major depressive disorder in 84 countries from 2000–2019.
30 Mar, 2022 | 09:49h | UTC
M-A: Effectiveness of cognitive–behavioral therapies of varying complexity in reducing depression in adults.
30 Mar, 2022 | 09:46h | UTCEffectiveness of cognitive–behavioural therapies of varying complexity in reducing depression in adults: systematic review and network meta-analysis – British Journal of Psychiatry (link to abstract – $ for full-text)
News Release: Enhanced CBT can radically reduce long-term depression, finds study – University of Manchester
Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers.
29 Mar, 2022 | 09:58h | UTCCumulative burden of psychiatric disorders and self-harm across 26 adult cancers – Nature Medicine
See also: Suicide risk and mortality among patients with cancer – Nature Medicine (if the link is paywalled, try this one)
Invited Commentary: Shining a light on the psychological burden of cancer – Nature Medicine
Commentary on Twitter
Patients with cancer who are diagnosed with a psychiatric disorder had a higher incidence of mortality and are at greater risk of self-harm compared with other patients with cancer, according to a paper published in @NatureMedicine. https://t.co/U5b7ODKSNd pic.twitter.com/816N6ZCfms
— Nature Portfolio (@NaturePortfolio) March 28, 2022
Scientists find that the impact of social media on wellbeing varies across adolescence.
29 Mar, 2022 | 09:56h | UTCNews Release: Scientists find that the impact of social media on wellbeing varies across adolescence – University of Cambridge
Original Study: Windows of developmental sensitivity to social media – Nature Communications
Commentaries:
Teenage social media use linked to less life-satisfaction for some – BBC
Social media may affect girls’ mental health earlier than boys’, study finds – The Guardian
Expert reaction to study on social media use and wellbeing over adolescence – Science Media Centre
Association of antipsychotic drug exposure in pregnancy with risk of neurodevelopmental disorders: a national birth cohort study.
29 Mar, 2022 | 08:46h | UTCAssociation of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study – JAMA Internal Medicine (free for a limited period)
European clinical guidelines for Tourette syndrome and other tic disorders.
29 Mar, 2022 | 08:26h | UTCPart I: assessment
Part II: psychological interventions
Part III: pharmacological treatment
Part IV: deep brain stimulation
Related: Guideline: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders
Study challenges the theory that light alcohol consumption benefits heart health.
28 Mar, 2022 | 10:09h | UTCNews Release: Large study challenges the theory that light alcohol consumption benefits heart health – Massachusetts General Hospital
Original Study: Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease – JAMA Network Open
Related: No amount of alcohol is good for the heart, says World Heart Federation.
Commentary on Twitter
Cohort study found confounding factors mediate the J-shaped association between alcohol intake & CVD. Genetic epidemiology suggests any amount of alcohol is associated with increased CVD risk, with exponential risk increases at heavier consumption levels. https://t.co/PrPDmyt87q
— JAMA Network Open (@JAMANetworkOpen) March 25, 2022
Cohort study: Long-term treatment with clozapine is associated with increased risk of hematological malignancies.
28 Mar, 2022 | 08:43h | UTCLong-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter
Clozapine associated with an increased risk of haematological malignancies with a dose-response effect.
More deaths than from agranulocytosis, but absolute risk small compared to overall mortality benefit with clozapine.https://t.co/BK3P7GgPiv
@TheLancetPsych— Jonathan Rogers (@drjprogers) March 24, 2022