Pharmacology/Pharmaceutical Industry | Page 17 of 172 | Links Medicus Content Curation & Alerts in Medicine

New from @ISMPP: new updated guidelines for publishing company-sponsored biomedical research include guidance on transparency and accountability, two increasingly high priorities for these studies: https://t.co/zcjIn40Uki pic.twitter.com/ygOv0nBMLn

— Annals of Int Med (@AnnalsofIM) August 30, 2022

Review | Direct-acting oral anticoagulant prescriptions in the emergency department.

27 Sep, 2022 | 13:08h | UTC

Direct-Acting Oral Anticoagulant Prescriptions in the ED – emDocs

Chimeric antigen receptor T cell therapy for cancer: clinical applications and practical considerations.

23 Sep, 2022 | 13:07h | UTC

Chimeric antigen receptor T cell therapy for cancer: clinical applications and practical considerations – The BMJ

Commentary on Twitter

Chimeric antigen receptor T cells have revolutionised the treatment of hematological malignancies.

What practical aspects of a patient’s journey through this treatment should clinicians know about and what are current best practices to manage toxicities?https://t.co/idlA2Lv9uR

— The BMJ (@bmj_latest) September 4, 2022

M-A of the association between new hypoglycemic agents and digestive diseases.

22 Sep, 2022 | 13:16h | UTC

Meta-analysis of the association between new hypoglycemic agents and digestive diseases – Medicine

Commentary: Spotlight on digestive risks of newer diabetes drugs – ACP Gastroenterology

A quality improvement study showed that a clinic–based aspirin deimplementation intervention can reduce inappropriate aspirin prescribing and bleeding in patients receiving warfarin for anticoagulation.

22 Sep, 2022 | 13:14h | UTC

Assessment of an Intervention to Reduce Aspirin Prescribing for Patients Receiving Warfarin for Anticoagulation – JAMA Network Open

News Release: Stopping aspirin when on a blood thinner lowers risk of bleeding, study finds – Michigan Medicine

Commentary on Twitter

An anticoagulation clinic–based #aspirin deimplementation intervention was associated with improved guideline-concordant aspirin use and fewer bleeding complications. https://t.co/kxKFZOdhae #Research

— JAMA Network Open (@JAMANetworkOpen) September 19, 2022

Observational study suggests an increased risk of adverse events with the use of perioperative Gabapentin for pain management.

21 Sep, 2022 | 13:20h | UTC

Perioperative Gabapentin Use and In-Hospital Adverse Clinical Events Among Older Adults After Major Surgery – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Perioperative Gabapentin Use in Older Adults: Revisiting Multimodal Pain Management – JAMA Internal Medicine (free for a limited period)

Commentary on Twitter

Study suggests that careful risk-benefit assessment is needed before prescribing #gabapentin for perioperative #PainManagement to older patients. https://t.co/GDxupdEjeT #Research

— JAMA Internal Medicine (@JAMAInternalMed) September 19, 2022

Review | Obesity and contraceptive use: impact on cardiovascular risk.

16 Sep, 2022 | 12:53h | UTC

Obesity and contraceptive use: impact on cardiovascular risk – ESC Heart Failure

News Release: Combined birth control pill linked with increased risk of blood clots in obese women – European Society of Cardiology

Study | Vitamin D3 and omega-3 fatty acids not helpful in reducing the risk of frailty.

14 Sep, 2022 | 13:20h | UTC

News Release: Vitamin D3 and omega-3 fatty acids not helpful in reducing risk of frailty – Brigham and Women’s Hospital

Original Study: Effect of Vitamin D₃ and Omega-3 Fatty Acid Supplementation on Risk of Frailty: An Ancillary Study of a Randomized Clinical Trial – JAMA Network Open

Invited Commentary: There Is No Magic Pill to Prevent Frailty—You Still Have to Eat Your Vegetables – JAMA Network Open

Commentary on Twitter

New findings from the VITAL trial do not support the routine use of vitamin D3 or omega-3 fatty acid supplementation in community-dwelling older adults for the prevention of frailty. #OAResearch https://t.co/LIJO8bJ0Wk #OAResearch

— JAMA Network Open (@JAMANetworkOpen) September 13, 2022

Network M-A | Comparative efficacy of lipid‐lowering therapies added to maximally tolerated statins for the reduction of LDL cholesterol.

11 Sep, 2022 | 22:38h | UTC

Network Meta‐Analysis of Randomized Trials Evaluating the Comparative Efficacy of Lipid‐Lowering Therapies Added to Maximally Tolerated Statins for the Reduction of Low‐Density Lipoprotein Cholesterol – Journal of the American Heart Association

Nonadherence was revealed through measurements of serum concentrations of antihypertensive drugs in one-third of patients with resistant hypertension previously evaluated as adherent.

11 Sep, 2022 | 22:35h | UTC

Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7‐Year Follow‐Up of Patients Considered Adherent by Directly Observed Therapy – Journal of the American Heart Association

Guideline Summary | Management of patients with suspected or confirmed antibiotic allergy.

8 Sep, 2022 | 14:42h | UTC

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

Perspective | Psychedelic drugs take on depression.

8 Sep, 2022 | 14:32h | UTC

Psychedelic drugs take on depression – Nature

Systematic Review | Probiotics for preventing acute upper respiratory tract infections.

6 Sep, 2022 | 14:40h | UTC

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

Commentary on Twitter

#probiotics for preventing colds? @CochraneARI looked at 24 studies w 6,950 people.
👍 may be beneficial in preventing at least 1 occurrence of acute upper respiratory tract infection #URTI & likely beneficial in preventing 3 occurrences of URTIs.https://t.co/A6XxrjKKcI pic.twitter.com/mDR3NYLLzQ

— The Cochrane Library (@CochraneLibrary) August 24, 2022

Study raises concerns about the effectiveness of the monkeypox vaccine.

6 Sep, 2022 | 14:39h | UTC

Study raises concerns about the effectiveness of the monkeypox vaccine – STAT

Original Study (Preprint): Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals – medRxiv

Systematic Review | Opioid agonist treatment for people who are dependent on pharmaceutical opioids.

6 Sep, 2022 | 14:31h | UTC

Opioid agonist treatment for people who are dependent on pharmaceutical opioids – Cochrane Library

Summary: Opioid maintenance medicines for the treatment of dependence on opioid pain medicines – Cochrane Library

Review | Cardiovascular complications of immune checkpoint inhibitors for cancer.

6 Sep, 2022 | 14:20h | UTC

Cardiovascular complications of immune checkpoint inhibitors for cancer – European Heart Journal

Major Adverse Cardiac Events With Immune Checkpoint Inhibitors: A Pooled Analysis of Trials Sponsored by the National Cancer Institute—Cancer Therapy Evaluation Program – Journal of Clinical Oncology

Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment – Journal of the American Heart Association

Cardiotoxicity of immune checkpoint inhibitors – ESMO Open

Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature

Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association

Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology

Commentary on Twitter

Must read state-of-the-art review: Cardiovascular complications of immune checkpoint inhibitors for cancer https://t.co/0lr7g6s8g0
#EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/jORaTzP7GD

— European Society of Cardiology Journals (@ESC_Journals) September 5, 2022