Pharmacology/Pharmaceutical Industry
Review – Cardiotoxicity of cancer chemotherapy: identification, prevention and treatment
12 Oct, 2017 | 18:01h | UTCRelated Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free) AND Radiation Associated Cardiac Disease – American College of Cardiology, Latest in Cardiology (free) AND Cardiac Toxicity Of Cancer Chemotherapy – US Cardiology Review (free)
Review: The importance of immunization in cancer prevention, treatment, and survivorship
12 Oct, 2017 | 18:02h | UTC
Review: Renal Function Considerations for Stroke Prevention in Atrial Fibrillation
12 Oct, 2017 | 17:59h | UTC
Review: perioperative pain management in opioid-tolerant patients
12 Oct, 2017 | 17:59h | UTC
Guideline: Treatment for Acute Cough Associated With the Common Cold
11 Oct, 2017 | 01:43h | UTCSee also other recent CHEST guidelines on the management of cough in specific populations: Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough: CHEST Guideline and Expert Panel Report (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis: CHEST Guideline and Expert Panel Report (free)
Study links dental antibiotics to C diff cases
10 Oct, 2017 | 01:10h | UTCStudy links dental antibiotics to C diff cases – CIDRAP (free) AND Antibiotics for dental procedures linked to superbug infection – Infectious Diseases Society of America, via ScienceDaily (free)
Study Presented at #IDWeek2017
Research: Single-Tablet HIV Therapy
10 Oct, 2017 | 01:08h | UTCCommentaries: Towards a universal second-line fixed-dose combination ART – The Lancet HIV (free) AND Single-Tablet ART: New Hope in HIV Therapy? All-in-one fixed dose combo proves safe, effective in EMERALD trial – MedPage Today (free registration required) AND EMERALD Trial: Week 48 Results Demonstrate Efficacy in Single-Tablet HIV Therapy – Infectious Diseases Advisor (free)
Study Presented at #IDWeek2017
Research: Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada
10 Oct, 2017 | 01:05h | UTCCommentaries: Generic Blood Pressure Drugs May Be Tied to Increase in Adverse Events – Physician’s First Watch (free) AND Generic ARBs Linked to Increased Adverse Events – TCTMD (free)
As in any observational study, association does not necessarily imply causation.
Research: Antenatal nutritional supplementation and autism spectrum disorders
7 Oct, 2017 | 22:43h | UTCCommentaries: Multivitamins in pregnancy may be linked to lower autism risk in children – ScienceDaily (free) AND Could multivitamin use in pregnancy protect children from autism? – Medical News Today (free) AND Multivitamin Use in Pregnancy Might Be Tied to Lower Autism Risk in Offspring – Physician’s First Watch (free)
Research: Availability of evidence of benefits on overall survival and quality of life of cancer drugs
7 Oct, 2017 | 22:44h | UTCEditorials: Do cancer drugs improve survival or quality of life? (free) AND Cancer drugs: high price, uncertain value (free)
Commentaries: Over half of new cancer drugs ‘show no benefits’ for survival or wellbeing – The Guardian (free) AND Only half of new cancer drugs extend or improve life – OnMedica (free) AND Some cancer drugs approved in Europe might not have sufficient evidence of survival benefits, says study – Cancer Research UK (free)
Research: Use of Non–Vitamin K Oral Anticoagulants With and Without Concurrent Medications and Risk of Major Bleeding
7 Oct, 2017 | 22:37h | UTCAssociation Between Use of Non–Vitamin K Oral Anticoagulants With and Without Concurrent Medications and Risk of Major Bleeding in Nonvalvular Atrial Fibrillation – JAMA (link to abstract – $ for full-text)
Commentaries: Use of Non-Vitamin K Blood-Thinners with Certain Medications Associated With Increased Risk of Major Bleeding – The JAMA Network (free) AND Drug reactions with NOACs in AFib patients could result in major bleeding problems – Cardiovascular Business (free)
Research: Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine
7 Oct, 2017 | 22:27h | UTCCommentaries: First human trial of DNA-based Zika vaccine shows promise – CIDRAP (free) AND DNA-based Zika vaccine candidate found safe and effective at inducing immune response – University of Pennsylvania School of Medicine, via EurekAlert (free) AND Zika vaccine shows promise in early human trial – Reuters (free)
Research: Association Between Use of Antithrombotic Medication and Hematuria-Related Complications
7 Oct, 2017 | 22:29h | UTCAssociation Between Use of Antithrombotic Medication and Hematuria-Related Complications – JAMA (link to abstract – $ for full-text)
Commentaries: Antithrombotics Associated with Gross Hematuria – Physician’s First Watch (free) AND Haematuria more common in people taking antithrombotics – OnMedica (free)
Opinion – The high price of anticancer drugs: origins, implications, barriers, solutions
7 Oct, 2017 | 22:30h | UTCOpinion: The high price of anticancer drugs: origins, implications, barriers, solutions – Nature Reviews: Clinical Oncology (free PDF)
Related: Cancer drugs are getting better and dearer – The Economist (a few articles per month are free) Financial toxicity: 1 in 3 cancer patients have to turn to friends or family to pay for care – STAT News (free) AND Not Just Nausea And Vomiting: Cancer Docs Now Worry About ‘Financial Toxicity’ – WBUR AND Financial Toxicity and Cancer Treatment (PDQ®) – National Institute of Cancer (free) AND Financial Toxicity: Cancer Supportive Care Professionals Consider the Side Effects of Soaring Costs – ASCO Post (free)
Review: Fluconazole resistance in Candida species
7 Oct, 2017 | 22:06h | UTCFluconazole resistance in Candida species: a current perspective – Infection and Drug Resistance (free)
Review: Perioperative management and monitoring of antiplatelet agents
7 Oct, 2017 | 21:58h | UTC
Meta-analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate for drinking disorder
7 Oct, 2017 | 21:43h | UTCCommentary: Pills prescribed for alcoholism might not work, study finds – The Guardian (free)
Research: Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events
7 Oct, 2017 | 21:41h | UTCPharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events – Diabetes Care (link to abstract – $ for full-text)
Commentary: Cardiac Risk the Same With All Sulfonylureas in Diabetes – Medscape (free registration required)
Guidelines of Insulin Pump Therapy and Continuous Glucose Monitor Management of Diabetes
7 Oct, 2017 | 21:17h | UTCKeeping Up with the Diabetes Technology: 2016 Endocrine Society Guidelines of Insulin Pump Therapy and Continuous Glucose Monitor Management of Diabetes – Current Diabetes Reports (free) – checar acesso
Research: D-dimer to guide the intensity of anticoagulation after mechanical heart valve replacement
1 Oct, 2017 | 16:24h | UTCD-dimer to guide the intensity of anticoagulation in Chinese patients after mechanical heart valve replacement: a randomized controlled trial – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
Research: Effect of a Community Health Worker–Led Multicomponent Intervention on Blood Pressure Control
1 Oct, 2017 | 16:13h | UTCEffect of a Community Health Worker–Led Multicomponent Intervention on Blood Pressure Control in Low-Income Patients in Argentina: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Community Intervention among Low-Income Patients Results in Improved Blood Pressure Control – The JAMA Network (free)
“The proportion of patients with controlled hypertension (BP <140/90 mm Hg) increased from 17 percent at baseline to 73 percent in the intervention group and from 18 percent to 52 percent in the usual care group”.
Guideline: Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups
1 Oct, 2017 | 16:07h | UTCNews release: WHO recommends large-scale deworming to improve children’s health and nutrition (free)
Infographic: WHO publishes recommendations for large-scale deworming to improve children’s health and nutrition (free)
See also: WHO intestinal worms website (free resources) AND Fact sheet: Soil-transmitted helminth infections (free)
Study Questions Use of Acid Suppressors To Curb Mild Infant Reflux
1 Oct, 2017 | 16:09h | UTCMedical News & Perspectives: Study Questions Use of Acid Suppressors To Curb Mild Infant Reflux – JAMA (free) (RT @DeeMangin see Tweet)
Study abstract presented at the Pediatric Academic Societies meeting: Infants prescribed antacids for reflux have increased risk of bone fractures (free)
Review: Chronic heart failure
1 Oct, 2017 | 15:06h | UTCChronic heart failure – Australian Prescriber (free)
Source: Cardiology Research Review Australia
Review: Lipid lowering in renal disease
1 Oct, 2017 | 15:06h | UTCLipid lowering in renal disease – Australian Prescriber (free)
Source: Cardiology Research Review Australia