Pharmacology/Pharmaceutical Industry | Page 140 of 172 | Links Medicus Content Curation & Alerts in Medicine

“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)

Randomized Trial: Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults

16 Nov, 2018 | 02:24h | UTC

Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial – JAMA (free for a limited period)

Video Summary: Effect of a Pharmacist-Led Intervention on Inappropriate Prescriptions in Older Adults (free)

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

16 Nov, 2018 | 01:08h | UTC

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease – New England Journal of Medicine (free)

Editorial: VITAL Signs for Dietary Supplementation to Prevent Cancer and Heart Disease (free)

Commentaries: Vitamin D And Fish Oil Supplements Mostly Disappoint In Long-Awaited Research Results – NPR (free) AND Fish Oil And Vitamin D Pills No Guard Against Cancer Or Serious Heart Trouble – Kaiser Health News (free)

Systematic Review: Supplements for Preventing Cognitive Decline in People with Mild Cognitive Impairment

9 Nov, 2018 | 01:59h | UTC

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)

Summary: Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)

“The evidence on vitamin and mineral supplements as treatments for MCI is very limited. “

Deprescribing: The Fightback Against Polypharmacy Has Begun

5 Nov, 2018 | 12:11h | UTC

Deprescribing: the fightback against polypharmacy has begun – The Pharmaceutical Journal (free) (via @Deprescribing)

Meta-Analysis: Comparative Efficacy of Inhaled Medications for COPD

5 Nov, 2018 | 11:48h | UTC

Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis – International Journal of Chronic Obstructive Pulmonary Disease (free)

NICE Antimicrobial Prescribing Guidelines

2 Nov, 2018 | 03:51h | UTC

Antimicrobial prescribing guidelines – National Institute for Health and Care Excellence (free resources)

Just Published Guidelines: Urinary tract infection (lower): antimicrobial prescribing (free) AND Urinary tract infection (recurrent): antimicrobial prescribing (free) AND Pyelonephritis (acute): antimicrobial prescribing (free) AND Prostatitis (acute): antimicrobial prescribing (free)

Review: Side Effects of Long‐Term Proton Pump Inhibitor Use

2 Nov, 2018 | 03:40h | UTC

Side Effects of Long‐Term Proton Pump Inhibitor Use: A Review – Basic & Clinical Pharmacology & Toxicology (free)

Systematic Review: Prophylactic Antibiotic Therapy for COPD

2 Nov, 2018 | 03:36h | UTC

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)

Summary: Preventative antibiotic therapy for people with COPD – Cochrane Library (free)

“Use of continuous and intermittent prophylactic antibiotics results in a clinically significant benefit in reducing exacerbations in COPD patients.”

Study: Antibiotic and Acid-Suppression Medications During Early Childhood are Associated with Obesity

2 Nov, 2018 | 03:32h | UTC

Antibiotic and acid-suppression medications during early childhood are associated with obesity – Gut (free)

Commentaries: Expert reaction to antibiotic and antacid use in early childhood and risk of obesity – Science Media Centre (free) AND Antibiotic Exposure in Early Life Tied to Slightly Higher Obesity Risk – NEJM Journal Watch (free) AND Antibiotics, H2RAs and PPIs linked to child obesity – OnMedica (free) AND Two studies tie early antibiotic exposure to increased obesity risk – CIDRAP (free)

Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions

2 Nov, 2018 | 03:29h | UTC

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies – Pain (free)

“It seems unlikely that cannabinoids are highly effective medicines for chronic noncancer pain conditions.”

Randomized Trial: Oral Curcumin in Elective Abdominal Aortic Aneurysm Repair

2 Nov, 2018 | 03:19h | UTC

Oral curcumin in elective abdominal aortic aneurysm repair: a multicentre randomized controlled trial – Canadian Medical Association Journal (free)

Editorial: Take turmeric with a grain of salt (free)

Commentary: Oral curcumin shows no benefit in reducing inflammation following vascular surgery – Canadian Medical Association Journal (free)

Systematic Review: Drug-Induced Interstitial Lung Disease

2 Nov, 2018 | 02:54h | UTC

Drug-Induced Interstitial Lung Disease: A Systematic Review – Journal of Clinical Medicine (free)

Commentary: Drugs’ side effects in lungs ‘more widespread than thought’ – The University of Manchester (free)

Guideline: Antiplatelet Therapy in Patients Undergoing Elective Invasive Procedures

26 Oct, 2018 | 02:58h | UTC

Management of antiplatelet therapy in patients undergoing elective invasive procedures. Proposals from the French Working Group on perioperative haemostasis (GIHP) and the French Study Group on thrombosis and haemostasis (GFHT). In collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR) (free)

Randomized Trial: Proton-Pump Inhibitors Prophylaxis of Little Benefit in the ICU

26 Oct, 2018 | 02:41h | UTC

Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU – New England Journal of Medicine (free for a limited period)

Editorial: Proton-Pump Inhibitor Prophylaxis in the ICU — Benefits Worth the Risks? (free for a limited period)

“Proton pump inhibitors are minimally effective to reduce GI bleeding among the critically ill folks at high risk for stress ulcers. Takeaways: no role for routine PPI for any patients on the WARDS, and shouldn’t be considered ‘routine’ in the ICU” (via @AnilMakam see Tweet)

Cohort Study: Angiotensin Converting Enzyme Inhibitors and Risk of Lung Cancer

26 Oct, 2018 | 02:43h | UTC

Angiotensin converting enzyme inhibitors and risk of lung cancer: population based cohort study – The BMJ (free)

Editorial: Angiotensin converting enzyme inhibitors and lung cancer (free)

Commentaries: Blood pressure drug linked to possible small increased risk of lung cancer – NHS Choices (free) AND Expert reaction to study looking at blood pressure drugs and lung cancer risk – Science Media Centre (free)

Meta-Analysis: Efficacy, Effectiveness, and Safety of Herpes Zoster Vaccines

26 Oct, 2018 | 02:42h | UTC

Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis – The BMJ (free)

“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”

Meta-Analysis: Cefazolin vs. Antistaphylococcal Penicillins for MSSA Bacteremia

26 Oct, 2018 | 02:27h | UTC

Efficacy and safety of cefazolin versus antistaphylococcal penicillins for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia: a systematic review and meta-analysis – BMC Infectious Diseases (free)

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