Pharmacology/Pharmaceutical Industry
Preliminary study suggests chemotherapy delivery in the afternoon may improve outcomes in patients with DLBC lymphoma
1 Feb, 2023 | 13:27h | UTCCommentaries:
Chemotherapy schedule affects treatment outcomes in female DLBCL patients – News Medical
Review | Safety and effectiveness of NMDA receptor antagonists for depression
1 Feb, 2023 | 13:05h | UTC
M-A | Vancomycin area under the curve vs. trough only guided dosing and the risk of acute kidney injury
31 Jan, 2023 | 13:32h | UTC
A new study provides insights into the emotional ‘blunting’ caused by common antidepressants
30 Jan, 2023 | 01:05h | UTCNews Release: Scientists explain emotional ‘blunting’ caused by common antidepressants – University of Cambridge
Commentary from the authors: Emotional ‘blunting’ and antidepressants – new research suggests why this is happening – The Conversation
Commentary on Twitter
One of our top rated articles on @altmetric this week was published in @npp_journal. Read 'Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study' here: https://t.co/4W8XGoyYMn pic.twitter.com/C1XKcglGtW
— Springer Nature (@SpringerNature) January 27, 2023
FDA panel eyes shift to annual COVID shots
30 Jan, 2023 | 01:03h | UTCFDA panel eyes shift to annual COVID shots – CIDRAP
See also:
FDA advisers recommend updating Covid vaccines – STAT
U.S. Proposes to Make COVID Shot Annual, Much Like Flu Shot – HealthDay
Case Series | Higher Troponin was associated with persistent cardiac MRI lesions in children with myocarditis after mRNA-based COVID-19 vaccination
30 Jan, 2023 | 01:01h | UTC
Evaluation of systemic medications associated with surgically treated cataract among US adults
30 Jan, 2023 | 00:38h | UTCCommentary: Some systemic medications may be associated with increased cataract risk – 2 Minute Medicine
Overuse of medications in low- and middle-income countries: a scoping review
27 Jan, 2023 | 12:31h | UTC
Perspective | Were bivalent boosters worth it? The biggest questions about the newest Covid-19 vaccines are still unanswered
27 Jan, 2023 | 12:19h | UTC
SR | Barriers and facilitators to deprescribing of cardiovascular medications
27 Jan, 2023 | 12:09h | UTCRelated:
Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults
27 Jan, 2023 | 11:55h | UTC
Essential medicines for mental disorders: comparison of 121 national lists with WHO recommendations
26 Jan, 2023 | 12:55h | UTC
SR | Medication review in hospitalized patients to reduce morbidity and mortality
24 Jan, 2023 | 14:37h | UTCMedication review in hospitalised patients to reduce morbidity and mortality – Cochrane Library
Summary: What are the benefits and risks of medication reviews for hospitalized adults? – Cochrane Library
Commentary on Twitter (thread – click for more)
https://twitter.com/tlassers/status/1617499045005758467
FDA no longer needs to require animal tests before human drug trials
24 Jan, 2023 | 14:32h | UTCFDA no longer needs to require animal tests before human drug trials – Science
See also: The FDA no longer requires all drugs to be tested on animals before human trials – NPR
AHA Statement | Cancer therapy-related hypertension
23 Jan, 2023 | 13:46h | UTCTop Things to Know: Cancer Therapy-Related HTN – American Heart Association
Prescribing cascades: how to detect them, prevent them, and use them appropriately
23 Jan, 2023 | 13:41h | UTCRelated:
Evidence of a gabapentinoid and diuretic prescribing cascade among older adults with lower back pain – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Are you the victim of a prescribing cascade?
Prescribing Cascade in a Cardiology Practice
Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
18 Jan, 2023 | 14:37h | UTCSee calculator: https://vtepredict.com/
Commentary on Twitter
The effect of extended anticoagulant treatment for individual patients with venous thromboembolism: the results from the VTE-PREDICT risk score! #venous #thromboembolism #anticoagulant #bleeding #score#EHJ #cardiotwitter @ESC_Journals @escardio
https://t.co/u3NHWyB9rv pic.twitter.com/ifOFxaXV1I— EHJ Editor-in-Chief (@ehj_ed) January 17, 2023
Cohort Study | Proton pump inhibitors are unlikely to be major teratogens during pregnancy
18 Jan, 2023 | 14:14h | UTC
Commentary on Twitter
This large nationwide cohort study of 2.7 million pregnancies suggested that maternal proton pump inhibitor use during pregnancy is not associated with an increased risk of congenital malformations. https://t.co/fvgthhIYa7
— JAMA Network Open (@JAMANetworkOpen) January 10, 2023
Cohort Study | Safety and effects of buprenorphine-naloxone, buprenorphine, and methadone throughout pregnancy in maternal opioid use disorder
18 Jan, 2023 | 14:10h | UTCCommentary: Buprenorphine-Naloxone Appears Safe for Maternal Opioid Use Disorder – HealthDay
Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease
13 Jan, 2023 | 13:25h | UTCNews Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom
Commentaries:
Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP
Antibiotic Exposure Positively Linked to IBD Development – HealthDay
Commentary on Twitter
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al
"Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" viahttps://t.co/zc9bG3CpSm#GUTInTheNews pic.twitter.com/xra8wfEgnr
— Gut Journal (@Gut_BMJ) January 9, 2023
RCT | A 24-week, all-oral regimen for rifampin-resistant tuberculosis
12 Jan, 2023 | 13:27h | UTCA 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis – New England Journal of Medicine
Commentary: Trial results show superiority of shorter, all-oral treatment for drug-resistant TB – CIDRAP
Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis
11 Jan, 2023 | 14:30h | UTCCirculating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis – Circulation
Commentary: Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine – News Medical
RCT | Effect of prescriber notifications of patient’s fatal overdose on opioid prescribing at 4 to 12 months
10 Jan, 2023 | 14:50h | UTC
Commentary on Twitter
Letters notifying clinicians of a patient's fatal overdose reduced opioid prescribing up to one year after receiving the letter. https://t.co/cEU1inH9lE
— JAMA Network Open (@JAMANetworkOpen) January 6, 2023
Consensus Paper | Antipsychotic medication deprescribing among adult patients with critical illness
10 Jan, 2023 | 14:37h | UTC
Commentary on Twitter
#CritCareExplore @SCCM Prescribing recommendations in ICU patients: limit antipsychotics to those with hyperactive delirium, at risk of harm to self/others or w/ care impacts. @n_jaworska@kiramakuk@KarlaKrewulak@dan_niven@lisa_burry@geetamehta0 @kmfiest https://t.co/73GUvrfJls pic.twitter.com/TbjbnGxD8Y
— Critical Care Explorations (@CritCareExplore) December 4, 2022
ACP Guideline | Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults
9 Jan, 2023 | 14:59h | UTCSummary for Patients: Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults


