Pharmacology/Pharmaceutical Industry
Observational Study Suggests Use of Acid-Suppressing Drugs May Increase the Risk of Allergies
1 Aug, 2019 | 07:37h | UTCCommentaries: Stomach-protecting medicines can trigger allergies – Medical University of Vienna (free) AND Acid-Suppressing Drugs Tied to Later Use of Anti-Allergy Drugs – NEJM Journal Watch (free) AND Your heartburn drugs may be giving you allergies, study suggests – CNN (free)
Prescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies
30 Jul, 2019 | 01:26h | UTCPrescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies – JAMA (free for a limited period)
Review: Pharmacologic Considerations Surrounding Sedation, Delirium, and Sleep in Critically Ill Adults
29 Jul, 2019 | 20:16h | UTC
FDA Safety Alert: Drug to Treat Ulcerative Colitis and Arthritis May Increase the Risk of Blood Clots and Death with Higher Dose
29 Jul, 2019 | 20:19h | UTCFDA Drug Safety Communication: FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR) – U.S. Food & Drug Administration (free)
Commentary: Boxed Warnings Added to Drug for Ulcerative Colitis, Arthritis – NEJM Journal Watch (free)
Someday, an Arm Implant May Prevent H.I.V. Infection for a Year
29 Jul, 2019 | 20:15h | UTCSomeday, an Arm Implant May Prevent H.I.V. Infection for a Year – The New York Times (10 articles per month are free)
See also: New implant could be ‘game changing’ for HIV prevention – Science (free)
[Abstract Only] Fluoroquinolones Linked to Serious Arrhythmias and Sudden Death in Large Observational Study
28 Jul, 2019 | 22:47h | UTCFluoroquinolone use and serious arrhythmias: A nationwide case-crossover study – Resuscitation (link to abstract – $ for full-text)
Commentary: Fluoroquinolones and Sudden Death – JournalFeed (free)
Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries) AND FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries) AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones (free report and commentaries)
Recommendations for the Safe Management of Antineoplastic Medication in Cancer Patients
27 Jul, 2019 | 19:59h | UTC
Guideline: Medication-Related Osteonecrosis of the Jaw
24 Jul, 2019 | 09:22h | UTC
Clinical Use of Lithium Salts: Guide for Users and Prescribers
24 Jul, 2019 | 08:34h | UTC
[Abstract Only] Study Shows Widespread Use of Aspirin for Primary Prevention of CV Disease Despite Few Benefits
24 Jul, 2019 | 07:49h | UTCPrevalence of Aspirin Use for Primary Prevention of Cardiovascular Disease in the United States: Results From the 2017 National Health Interview Survey – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Widespread aspirin use despite few benefits, high risks – Beth Israel Deaconess Medical Center (free) AND Many Americans mistakenly use aspirin to prevent heart disease – Reuters (free) AND Older Adults Should Reevaluate Daily Aspirin – MedicalResearch.com (free) AND Millions still take aspirin for their heart without a doctor’s recommendation, research suggests – CNN (free)
Related Commentary on Twitter (Thread – Click for More)
New pub out today in @AnnalsofIM. Our main finding: aspirin use for primary prevention is widespread among groups at risk for harm. https://t.co/s9h9BhjYgz
— Colin W. O'Brien (@ColinWOBrien) July 22, 2019
Diversion of Controlled Drugs in Hospitals: A Scoping Review of Contributors and Safeguards
24 Jul, 2019 | 01:04h | UTC
WHO Recommends Dolutegravir as Preferred HIV Treatment Option in All Populations
23 Jul, 2019 | 02:03h | UTC
Related Commentary on Twitter
WHO recommends the use of the #HIV drug #dolutegravir as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential, based on new evidence from two large clinical trials in Africa https://t.co/owoDyXIMeZ pic.twitter.com/9qjpMnKgcY
— World Health Organization (WHO) (@WHO) July 22, 2019
Opinion: A Bird’s-eye View of Clinical Trials Provides New Perspectives on Drug Research and Development
21 Jul, 2019 | 21:26h | UTC
Perspective: Common Medications Can Masquerade As Dementia In Seniors
21 Jul, 2019 | 20:49h | UTCCommon Medications Can Masquerade As Dementia In Seniors – Kaiser Health News (free)
Studies: Industry Payments and Physician Prescribing
14 Jul, 2019 | 19:50h | UTCIndustry Payments and Physician Prescribing – JAMA Internal Medicine (free for a limited period)
Original Studies: Association of Biologic Prescribing for Inflammatory Bowel Disease With Industry Payments to Physicians – JAMA Internal Medicine (free for a limited period) AND Association Between Industry Payments to Physicians and Gabapentinoid Prescribing – JAMA Internal Medicine (free for a limited period)
Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers
12 Jul, 2019 | 07:44h | UTCCommentaries: No link between flu vaccine in pregnancy and later health problems in children – The BMJ (free) AND Swine flu jab in pregnancy safe for children as well as mothers – OnMedica (free)
Perspective – New Drugs: Where Did We Go Wrong and What Can We do Better?
12 Jul, 2019 | 07:13h | UTCNew drugs: where did we go wrong and what can we do better? – The BMJ (free)
Commentary: No evidence of added benefit for most new drugs entering German healthcare system – The BMJ (free)
Related Commentary on Twitter
https://twitter.com/bmj_latest/status/1149181569321623552
Drug-induced Endocrinopathies and Diabetes
11 Jul, 2019 | 10:27h | UTC
HPV Vaccine Could Prevent over 100,000 Cancers in the UK
11 Jul, 2019 | 09:41h | UTCPress Release: HPV vaccine could prevent over 100,000 cancers – Public Health England (free)
Commentaries: HPV vaccine for boys ‘will prevent thousands of cancers’ – BBC (free) AND Expert reaction to HPV vaccine, modelling of cancer prevention, and introduction in September of vaccine programme for boys – Science Media Centre (free) AND UK offers HPV vaccines to boys, aims to stop 100,000 cancer cases – Reuters (free)
WHO Updates Global Guidance on Medicines and Diagnostic Tests
10 Jul, 2019 | 10:25h | UTCGuidance: World Health Organization model list of essential medicines: 21st list 2019 (free PDF) AND Executive summary: the selection and use of essential medicines 2019 (free PDF) AND World Health Organization model list of essential medicines for children: 7th list 2019 (free PDF) AND Second WHO Model List of Essential In Vitro Diagnostics (free PDF)
Commentaries: WHO List of Essential Tests Gets An Upgrade – Forbes (free) AND WHO adds new antibiotics to essential medicines list – CIDRAP (free)
Androgen Deprivation Therapy Linked to Increased Risk of Dementia in Men with Prostate Cancer
10 Jul, 2019 | 09:30h | UTCCommentaries: Hormone therapy for prostate cancer may raise risk of Alzheimer’s, Dementia – Penn Medicine (free) AND Prostate cancer treatment linked to heightened Alzheimer’s risk – UPI (free) AND Men’s dementia risk higher after androgen deprivation therapy – OnMedica (free) AND Risk of dementia rises with prostate cancer hormone-blocking therapy – Reuters (free)
[Abstract Only] Little Evidence for Nutritional Supplements to Improve Cardiovascular Outcomes
9 Jul, 2019 | 10:19h | UTCEffects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Little evidence supports nutritional supplements for protection against cardiovascular disease, death – ACP Internist (free) AND Nutritional supplements and diets not always protective, WVU research suggests – West Virginia University (free) AND Supplements and Diets for Heart Health Show Limited Proof of Benefit – The New York Times (10 articles per month are free)
Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
[Abstract Only] Cohort Study: Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized with Pneumonia
9 Jul, 2019 | 10:13h | UTCExcess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized With Pneumonia: A Multihospital Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Pneumonia patients get too many antibiotics – especially as they leave the hospital – University of Michigan (free)
Related Commentary on Twitter
https://twitter.com/ABsteward/status/1148384237499899904
Guideline for the Antibiotic Use in Acute Gastroenteritis
8 Jul, 2019 | 10:18h | UTCGuideline for the Antibiotic Use in Acute Gastroenteritis – Infection & Chemotherapy (free)
Related: ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults – American Journal of Gastroenterology (free)
Recommendations for the Use of Opioids in Children During the Perioperative Period
8 Jul, 2019 | 10:05h | UTC