Pharmacology/Pharmaceutical Industry
Randomized Trial: Atezolizumab, Vemurafenib, and Cobimetinib for Advanced BRAFV600 Mutation-positive Melanoma
16 Jun, 2020 | 07:48h | UTC
Perspective: COVID-19 Vaccines for All?
15 Jun, 2020 | 03:24h | UTCCOVID-19 vaccines for all? – The Lancet
Medication Management and Pharmacokinetic Changes after Bariatric Surgery
15 Jun, 2020 | 03:12h | UTC
Position Statement: A Disease State Approach to the Pharmacological Management of Type 2 Diabetes in Primary Care
12 Jun, 2020 | 09:02h | UTC
Opinion: Collective Intelligence, Not Market Competition, Will Deliver the Best Covid-19 Vaccine
11 Jun, 2020 | 09:35h | UTCCollective intelligence, not market competition, will deliver the best Covid-19 vaccine – STAT
Coronavirus Vaccine Tracker
11 Jun, 2020 | 09:37h | UTCCoronavirus Vaccine Tracker – The New York Times
Reporting of Financial Conflicts of Interest by Canadian Clinical Practice Guideline Producers
11 Jun, 2020 | 09:22h | UTC
Covid-19: Three Big Studies Say Hydroxychloroquine Does Not Help
10 Jun, 2020 | 04:58h | UTCThree big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19 – Science
Original Studies: No Benefit From the Use of Hydroxychloroquine in Hospitalized Patients with COVID-19 AND Hydroxychloroquine Not Effective as Postexposure Prophylaxis for Covid-19
Related Commentary on Twitter
There's a 3rd new, negative randomized trial of hydroxychloroquine from Spain in 2,300 patients w/ #COVID19. Now what? https://t.co/QTApLuAfDp by @kakape @ScienceMagazine
— Eric Topol (@EricTopol) June 9, 2020
AGA Guideline: Probiotics Not Recommended for Most Digestive Conditions
10 Jun, 2020 | 04:48h | UTCNews Release: AGA does not recommend the use of probiotics for most digestive conditions
Risk of Hospitalization with Hemorrhage Among Older Adults Taking Clarithromycin vs. Azithromycin and Direct Oral Anticoagulants
9 Jun, 2020 | 04:33h | UTC
Randomized Trial: No Benefit From the Use of Hydroxychloroquine in Hospitalized Patients with COVID-19
8 Jun, 2020 | 04:42h | UTCStatement from the Chief Investigators of the Recovery Study: No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19
CHEST Guideline: Prevention, Diagnosis and Treatment of Venous Thromboembolism in Patients with COVID-19
8 Jun, 2020 | 04:39h | UTC
Meta-Analysis: Efficacy and Safety of Antiviral Treatment for COVID-19 from Evidence in Studies of SARSCoV-2 and Other Acute Viral Infections
8 Jun, 2020 | 04:56h | UTC
What Helps Older People Take Their Medication Correctly?
8 Jun, 2020 | 04:22h | UTCWhat helps older people take their medication correctly? – Evidently Cochrane
Original Review: Interventions for improving medication‐taking ability and adherence in older adults prescribed multiple medications – Cochrane Library
Lancet, New England Journal Retract Covid-19 Studies, Including one That Raised Safety Concerns About Malaria Drugs
5 Jun, 2020 | 05:07h | UTCScience: Two elite medical journals retract coronavirus papers over data integrity questions
Observational Study: Association of Hypertension and Antihypertensive Treatment with COVID-19 Mortality
5 Jun, 2020 | 05:05h | UTCEditorial: Renin–angiotensin system inhibitors in the COVID-19 pandemic: consequences of antihypertensive drugs
Commentaries: Expert reaction to study looking at link between high blood pressure and risk of dying from COVID-19 – Science Media Centre AND Blood pressure drugs linked to lower COVID-19 mortality: study – Reuters
COVID-19 Vaccine Development Pipeline Gears Up
5 Jun, 2020 | 04:59h | UTCCOVID-19 vaccine development pipeline gears up – The Lancet
Challenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development?
5 Jun, 2020 | 05:01h | UTCChallenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development? – JAMA
Related: Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development (other commentaries on the subject)
Case Series: Preliminary Study Evaluates the use of Famotidine for COVID-19 in Non-hospitalized Patients
5 Jun, 2020 | 04:57h | UTC
The Coronavirus Outbreak Could Make It Quicker and Easier to Trial Drugs
5 Jun, 2020 | 04:54h | UTCThe coronavirus outbreak could make it quicker and easier to trial drugs – Nature
Meta-Analysis: Effect of Low‐dose Aspirin on Health Outcomes
5 Jun, 2020 | 04:35h | UTCCommentary: Healthy people shouldn’t take daily aspirin to prevent heart disease, review finds – CNN
Randomized Trial: Hydroxychloroquine Not Effective as Postexposure Prophylaxis for Covid-19
4 Jun, 2020 | 05:12h | UTCEditorial: Hydroxychloroquine for the Prevention of Covid-19 — Searching for Evidence
Commentaries: Hydroxychloroquine does not prevent Covid-19 infection if exposed, study says – STAT AND The first high-quality study of malaria pill hydroxychloroquine just found it doesn’t help prevent coronavirus infections – Business Insider AND No Evidence Hydroxychloroquine Is Helpful In Preventing COVID-19, Study Finds – NPR
Perspective: Why a Vaccine May Not be Enough to End the Pandemic
4 Jun, 2020 | 04:54h | UTCWhy a vaccine may not be enough to end the pandemic – Vox
Randomized Trial: CPR–Guided Short Antibiotic Treatment Duration for Uncomplicated Gram-Negative Bacteremia
3 Jun, 2020 | 03:35h | UTCEffect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)
Cohort Study: Fexofenadine use During Pregnancy Does Not Appear to Be Associated with Increased Risk of Adverse Fetal Outcomes
3 Jun, 2020 | 03:31h | UTCAssociation Between Fexofenadine Use During Pregnancy and Fetal Outcomes – JAMA Pediatrics (free for a limited period)