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Pediatrics – Public Health

Randomized phase 1/2 trial: Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in children and adolescents aged 3–17 years.

23 Sep, 2021 | 10:16h | UTC

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial – The Lancet Infectious Diseases

Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

 

[Press release – not published yet] Pfizer announces COVID-19 vaccine in children 5 to 11 years produced strong neutralizing antibody responses.

21 Sep, 2021 | 09:57h | UTC

Pfizer and BioNTech Announce Positive Topline Results From Pivotal Trial of COVID-19 Vaccine in Children 5 to 11 Years – Pfizer and BioNTech

Commentaries:

Covid-19 vaccine for 5- to 11-year-olds is safe and shows ‘robust’ antibody response, Pfizer says – CNN

Pfizer says COVID-19 vaccine safe, effective in younger children – CIDRAP

Pfizer Covid-19 vaccine generates robust antibody response in children, without serious safety issues, company says – STAT

Expert reaction to press release giving topline results from Pfizer and BioNTech from their phase 2/3 trial looking at safety and antibody responses from their COVID-19 vaccine in children aged 5 to 11 – Science Media Centre

 

Commentaries on Twitter

(thread – click for more)

(thread – click for more)

 

An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy.

21 Sep, 2021 | 09:51h | UTC

An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy – American Journal of Obstetrics and Gynecology

 

Review: Long COVID symptoms in children rarely persist beyond three months.

19 Sep, 2021 | 23:47h | UTC

News release: Long COVID symptoms in children rarely persist beyond three months –  Murdoch Children’s Research Institute

Original study: How Common Is Long COVID in Children and Adolescents? – The Pediatric Infectious Disease Journal

Commentary: Long Covid in children and adolescents is less common than previously feared – The Guardian

Related:

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter (thread – click for more)

 

RCT: The addition of telemedicine to improve standard care for medically complex children was associated with improved clinical outcomes and reduced costs.

17 Sep, 2021 | 10:00h | UTC

Telemedicine for Children With Medical Complexity: A Randomized Clinical Trial – Pediatrics

 

Review | Prevention of unintentional injuries in children under five years.

17 Sep, 2021 | 09:58h | UTC

Prevention of unintentional injuries in children under five years – BMC Pediatrics

 

Perspective | Schools have begun mass testing for COVID-19. But hurdles and uncertainties remain.

16 Sep, 2021 | 10:06h | UTC

Schools have begun mass testing for COVID-19. But hurdles and uncertainties remain – Science

Related: Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

 

Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

15 Sep, 2021 | 10:01h | UTC

Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial – The Lancet

Invited commentary: Daily antigen testing to reduce disruption when schools return – The Lancet

 

Supplement: FIGO Working Group for Preterm Birth – Good Practice Recommendations.

15 Sep, 2021 | 08:56h | UTC

Homepage: FIGO Working Group for Preterm Birth – Good Practice Recommendations – International Journal of Gynecology & Obstetrics

Editorial: FIGO good practice recommendations for reducing preterm birth and improving child outcomes

FIGO good practice recommendations on the importance of registry data for monitoring rates and health systems performance in prevention and management of preterm birth

FIGO good practice recommendations on modifiable causes of iatrogenic preterm birth

FIGO good practice recommendations on reduction of preterm birth in pregnancies conceived by assisted reproductive technologies

FIGO good practice recommendations on progestogens for prevention of preterm delivery

FIGO good practice recommendations on cervical cerclage for prevention of preterm birth

FIGO good practice recommendations on the use of pessary for reducing the frequency and improving outcomes of preterm birth

FIGO good practice recommendations on the use of prenatal corticosteroids to improve outcomes and minimize harm in babies born preterm

FIGO good practice recommendations on magnesium sulfate administration for preterm fetal neuroprotection

FIGO good practice recommendations on delayed umbilical cord clamping

 

The Delta Covid variant and children: transmission in kids is low and only 2% hospitalized, report finds.

12 Sep, 2021 | 21:56h | UTC

The Delta Covid variant and children: transmission in kids is low and only 2% hospitalised, report finds – The Guardian

Report: COVID-19 Delta variant in schools and early childhood education and care services in NSW, Australia: 16 June to 31 July 2021 – NCIRS

News release: COVID-19 Delta variant in schools and early childhood education and care services in NSW, Australia: 16 June to 31 July 2021

 

Commentary on Twitter (thread – click for more)

 

Chile authorizes Sinovac vaccine for kids of 6 and older.

7 Sep, 2021 | 21:45h | UTC

Chile authorizes Sinovac vaccine for kids of 6 and older – Associated Press

 

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

7 Sep, 2021 | 21:48h | UTC

Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy – Nature Medicine

 

Commentaries on Twitter

 

AAP flu recommendations allow for coadministration with COVID-19 vaccine.

7 Sep, 2021 | 21:44h | UTC

News release: AAP flu recommendations allow for coadministration with COVID-19 vaccine – American Academy of Pediatrics

Guidance: Recommendations for Prevention and Control of Influenza in Children, 2021–2022 – American Academy of Pediatrics

Technical report: Recommendations for Prevention and Control of Influenza in Children, 2021–2022 – American Academy of Pediatrics

Related: New CDC Guidance says influenza and Covid vaccines can be given together – “COVID-19 vaccines and other vaccines may now be administered without regard to timing”

 

Commentary on Twitter

 

CDC report: Hospitalization rates for Covid-19 were 10 times higher among unvaccinated than among fully vaccinated adolescents.

7 Sep, 2021 | 10:52h | UTC

Hospitalizations Associated with COVID-19 Among Children and Adolescents — COVID-NET, 14 States, March 1, 2020–August 14, 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

More kids hospitalized with Covid-19 in states with lower vaccination rates, CDC report finds – CNN

The hospitalization rate among teens who are unvaccinated is 10 times higher than teens who are vaccinated, new CDC data shows – Insider

Child COVID hospital cases up in low-vaccination states – CIDRAP

 

Commentary on Twitter

 

Opinion | “The downsides of masking young students are real”.

3 Sep, 2021 | 10:24h | UTC

The Downsides of Masking Young Students Are Real – The Atlantic

 

Commentary with a rebuttal on Twitter (thread – click for more)

 

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

2 Sep, 2021 | 10:10h | UTC

Long COVID – the physical and mental health of children and non-hospitalised young people 3 months after SARS-CoV-2 infection; a national matched cohort study (The CLoCk) Study.

Commentaries:

Long Covid in children ‘nowhere near scale feared’ – BBC

Long covid: One in seven children may still have symptoms 15 weeks after infection, data show – The BMJ

Related:

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter (thread – click for more)

 

Global, regional, and national estimates and trends in stillbirths from 2000 to 2019: a systematic assessment.

1 Sep, 2021 | 08:56h | UTC

Global, regional, and national estimates and trends in stillbirths from 2000 to 2019: a systematic assessment – The Lancet

 

RCT: Severe malaria among young African children dramatically reduced through seasonal vaccination and preventative drug combination.

1 Sep, 2021 | 09:02h | UTC

News release: Severe malaria among young African children dramatically reduced through seasonal vaccination and preventative drug combination – London School of Hygiene & Tropical Medicine

Original article: Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention – New England Journal of Medicine

Commentary: Malaria trial shows ‘striking’ 70% reduction in severe illness in children – The Guardian

Related: Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

 

Study shows young children gained weight during the pandemic.

31 Aug, 2021 | 08:59h | UTC

News release: Young children gained weight during the pandemic – Kaiser Permanente

Original study: Changes in Body Mass Index Among Children and Adolescents During the COVID-19 Pandemic – JAMA

 

Commentary on Twitter

 

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

31 Aug, 2021 | 08:57h | UTC

Do kids get long COVID? And how often? A paediatrician looks at the data – The Conversation

Related:

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 

Many predicted some kind of ‘Covid slide’ in learning. Test results show how bad it is.

29 Aug, 2021 | 18:55h | UTC

Many predicted some kind of ‘Covid slide’ in learning. Test results show how bad it is – CNN

Report: Learning during COVID-19: Reading and math achievement in the 2020-21 school year – NWEA

Related:

[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.

 

Unvaccinated, unmasked teacher infected more than half of students in class with Covid-19, CDC reports.

29 Aug, 2021 | 18:52h | UTC

Unvaccinated, unmasked teacher infected more than half of students in class with Covid-19, CDC reports – CNN

Original study: Outbreak Associated with SARS-CoV-2 B.1.617.2 (Delta) Variant in an Elementary School — Marin County, California, May–June 2021 – CDC Morbidity and Mortality Weekly Report

 

Systematic review: The impact of COVID-19 lockdown on child and adolescent mental health.

25 Aug, 2021 | 08:58h | UTC

The impact of COVID-19 lockdown on child and adolescent mental health: systematic review – European Child & Adolescent Psychiatry

Related: M-A: Child and youth mental health problems have doubled during COVID-19. (several articles on the subject)

 

Thirty-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – “Despite negligible fatality, complications including hospitalization, hypoxemia, and pneumonia were more frequent in children and adolescents with COVID-19 than with influenza”.

24 Aug, 2021 | 09:51h | UTC

Thirty-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics

Related:

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

AAP Guidance: Post-COVID-19 conditions in children and adolescents.

Cohort study: Risk factors for long covid in previously hospitalized children.

Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Deaths from COVID ‘incredibly rare’ among children.

[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

 

Perspective | How should schools and daycare treat colds in the covid age? It’s complicated. – “Will every sniffle and cough be treated as potential Covid until proven otherwise?”.

24 Aug, 2021 | 09:53h | UTC

How Should Schools And Daycare Treat Colds In The Covid Age? It’s Complicated. – Romper

 

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