Pediatrics – Neurology | Page 4 of 5 | Links Medicus Content Curation & Alerts in Medicine

Observational Study: Comparison of intracranial pressure measurements before and after hypertonic saline or mannitol treatment in children with severe traumatic brain injury.

14 Mar, 2022 | 00:51h | UTC

Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury – JAMA Network Open

Invited Commentary: ADAPTing to a New Era of Comparative Effectiveness Research in Traumatic Brain Injury—Generating Evidence From Observational Data – JAMA Network Open

Commentary on Twitter

For children with severe TBI, hypertonic saline is recommended in published guidelines. However, mannitol is in wide-spread clinical use. In this comparative effectiveness, hypertonic saline was associated with improved ICP compared to mannitol. https://t.co/7JW224Dbio

— JAMA Network Open (@JAMANetworkOpen) March 10, 2022

Association of acute respiratory failure in early childhood with long-term neurocognitive outcomes.

9 Mar, 2022 | 08:41h | UTC

Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link to abstract – $ for full-text)

Commentaries:

IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay

Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes – University of Pennsylvania School of Nursing

Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.

4 Mar, 2022 | 09:54h | UTC

Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children’s Study – JAMA Pediatrics

Commentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

Mortality from congenital Zika Syndrome — nationwide cohort study in Brazil.

24 Feb, 2022 | 10:18h | UTC

Mortality from Congenital Zika Syndrome — Nationwide Cohort Study in Brazil – New England Journal of Medicine

Opinion | There’s no autism epidemic. But there is an autism diagnosis epidemic.

13 Feb, 2022 | 22:02h | UTC

There’s no autism epidemic. But there is an autism diagnosis epidemic – STAT

Study shows a lack of association of Group A Streptococcal infections and onset of tics.

13 Feb, 2022 | 22:04h | UTC

Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study – Neurology (link to abstract – $ for full-text)

News Release: Does strep throat lead to the development of tics? – American Academy of Neurology

Commentaries:

Strep Does Not Lead to Tics, Study Finds – NeurologyToday

Group A Strep Infection Not Tied to Tics in Children With Family History – HealthDay

Commentary on Twitter

Very important study to further remove us away from Group-A streptococcal infections and tics in families with primary tic disorders! https://t.co/HwHVrxNSqJ

— Christos Ganos (@ChristosGanos) February 9, 2022

Babies born during pandemic’s first year score slightly lower on a developmental screening test.

11 Feb, 2022 | 08:46h | UTC

News Release: Babies born during pandemic’s first year score slightly lower on a developmental screening test – Columbia University Irving Medical Center

Original Study: Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection – JAMA Pediatrics

Editorial: Understanding the Effects of the Pandemic on Infant Development—The Preterm Problem

Commentaries:

Covid-19: Babies born during the pandemic show slight development delays – The BMJ

Pandemic birth tied to poor development – CIDRAP

Concussion management is changing as more research suggests exercise is the best approach.

1 Feb, 2022 | 08:27h | UTC

Concussion management is changing as more research suggests exercise is best approach – The Conversation

Guideline: Nonpharmacological treatment of persistent postconcussion symptoms in adults.

RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

Cohort Study: Association of preeclampsia and perinatal complications with offspring neurodevelopmental and psychiatric disorders.

30 Jan, 2022 | 13:51h | UTC

Association of Preeclampsia and Perinatal Complications With Offspring Neurodevelopmental and Psychiatric Disorders – JAMA Network Open

WHO systematic review and meta-analysis: efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children.

28 Jan, 2022 | 08:27h | UTC

Efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children: a WHO systematic review and meta-analysis – Pain

5 years later, researchers assess how children exposed to Zika are developing.

14 Jan, 2022 | 07:53h | UTC

5 years later, researchers assess how children exposed to Zika are developing – NPR

The COVID generation: how is the pandemic affecting kids’ brains?

13 Jan, 2022 | 08:53h | UTC

The COVID generation: how is the pandemic affecting kids’ brains? – Nature

RCT: In full-term and near-term neonates, drug treatment of all clinically and electrographically detected seizures was not associated with reduced death rates or disability at 2 years compared with the treatment of only the clinically detected seizures.

13 Jan, 2022 | 08:24h | UTC

Effect of Treatment of Clinical Seizures vs Electrographic Seizures in Full-Term and Near-Term Neonates: A Randomized Clinical Trial – JAMA Network Open

Commentaries:

Should we treat electrographic seizures? – Neonatal Research

Subclinical Electrographic Seizures in the Newborn—Is More Treatment Better? – JAMA Network Open

Neonatal Seizures: Little Difference Between EEG/Clinical Treatment – Physician’s Weekly

Commentary on Twitter

NEST trial in @JAMANetworkOpen by @rodwhunt explores if treatment of EEG + clinical seizures compared with only treating clinical seizures in encephalopathic infants decreased odds of severe disability at 2 years of age. https://t.co/s3yYi6R3fV #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/xoxVKC2a5z

— Evidence-Based Neo (@EBNEO) December 29, 2021

RCT: Oxytocin does not improve social functioning in children with autism spectrum disorder.

14 Oct, 2021 | 09:52h | UTC

News release: Oxytocin does not improve social functioning in children with autism spectrum disorder, NIH-funded study suggests – National Institutes of Health

Original study: Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder – New England Journal of Medicine

RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

11 Oct, 2021 | 23:58h | UTC

Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial – The Lancet Child & Adolescent Health

News release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

Commentaries on Twitter

RCT study in @TheLancet shows adolescents who sub-threshold aerobic exercise 20 mins/ day for 4 weeks starting within 10 days of a concussion are 48% less likely to get prolonged symptoms. https://t.co/1tafsQHrXt

— Dr Ademola Adejuwon (@SmileySportyDoc) October 2, 2021

Sport-related #concussion is a major public health issue in US adolescents

This new RCT of aerobic exercise vs stretching found exercise sped up recovery and reduced risk for persistent post-concussive symptomshttps://t.co/jP30N1eJEQ pic.twitter.com/ux42VSMfSr

— The Lancet Child & Adolescent Health (@LancetChildAdol) October 1, 2021

Neurological Effects of COVID-19 in Children.

1 Oct, 2021 | 10:40h | UTC

Neurological Effects of COVID-19 in Children – Pediatric Clinics of North America

RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.

21 Sep, 2021 | 09:01h | UTC

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)

Commentaries:

Intervening Before 18 Months May Reduce Odds of Autism Diagnosis in Babies Identified at High Risk – Psychiatric News Alert

Expert reaction to trial looking at the effect of a pre-emptive intervention in children showing early signs of autism on developmental outcomes – Science Media Centre

Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian

Commentary on Twitter

An Australian randomized clinical trial found that ‘pre-emptive’ therapy during infancy reduced #autism diagnostic behaviors and improved language ability across early childhood https://t.co/Sybbu4hRWL

— JAMA Pediatrics (@JAMAPediatrics) September 20, 2021

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

12 Sep, 2021 | 21:38h | UTC

News release: Limiting screen time for young adults after concussion results in shorter duration of symptoms – University of Massachusetts Medical School

Original study: Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Commentary on Twitter

The use of electronic screen time in the first 48 hours after sustaining a concussion is associated with a longer time to recovery, a single-center randomized-clinical trial reports https://t.co/PFAj5OoqNc

— JAMA Pediatrics (@JAMAPediatrics) September 7, 2021

[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.

16 Aug, 2021 | 01:11h | UTC

Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Health – medRxiv

Commentary: Children born during pandemic have lower IQs, US study finds – Researchers blame lack of stimulation as parents balanced childcare with working from home – The Guardian

Commentary on Twitter (thread – click for more)

Preprint on the development of children born before and during the pandemic in the US.

"We find that children born during the pandemic have significantly reduced verbal, motor, and overall cognitive performance compared to children born pre-pandemic."
1/https://t.co/NInexSUDAi

— Prof Francois Balloux (@BallouxFrancois) August 15, 2021

European guideline and expert statements on the management of narcolepsy in adults and children.

13 Aug, 2021 | 09:02h | UTC

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

RCT: Therapeutic hypothermia may cause harm in moderate or severe neonatal encephalopathy in low-income and middle-income countries.

5 Aug, 2021 | 08:43h | UTC

Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh – The Lancet Global Health

News release: Brain injury treatment may cause harm in low and middle income nations – Imperial College London

Commentary: Hypoxic ischaemic encephalopathy in low resource settings—time to stop cooling? – The Lancet Global Health

Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.

26 Jul, 2021 | 02:58h | UTC

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study – The Lancet Child & Adolescent Health

Commentaries:

Neuroinflammation triggered by SARS-CoV-2 infection: syndromes and therapies – The Lancet Child & Adolescent Health

New UK study reveals extent of brain complications in children hospitalized with COVID-19 – University of Liverpool

Commentary on Twitter

A UK national prospective study of brain involvement in children hospitalized with covid: wide range of neurologic complications in 51 kidshttps://t.co/4JvjbthgH4 @LancetChildAdol pic.twitter.com/IiXF9bVmKz

— Eric Topol (@EricTopol) July 14, 2021