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Pediatrics – Neurology

RCT: Effect of different corticosteroid dosing regimens on clinical outcomes in boys with Duchenne Muscular Dystrophy.

7 Apr, 2022 | 08:53h | UTC

Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial – JAMA (free for a limited period)

Related:

RCT: Routine lung volume recruitment is not beneficial for boys with Duchenne muscular dystrophy.

Phase 2 RCT: Repeated intravenous cardiosphere-derived cell therapy in late-stage Duchenne muscular dystrophy.

Research: Long-term effects of glucocorticoids in patients with Duchenne muscular dystrophy

 

Commentary on Twitter

 


Association of antipsychotic drug exposure in pregnancy with risk of neurodevelopmental disorders: a national birth cohort study.

29 Mar, 2022 | 08:46h | UTC

Association of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study – JAMA Internal Medicine (free for a limited period)

Commentary: Antipsychotic Use During Pregnancy Generally Not Associated With Neurodevelopmental Risks – Psychiatric News Alert

 


European clinical guidelines for Tourette syndrome and other tic disorders.

29 Mar, 2022 | 08:26h | UTC

Summary statement

Part I: assessment

Part II: psychological interventions

Part III: pharmacological treatment

Part IV: deep brain stimulation

Related: Guideline: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders

 


Cohort Study: Risk of mental health problems in children and youths following concussion.

25 Mar, 2022 | 08:29h | UTC

Risk of Mental Health Problems in Children and Youths Following Concussion – JAMA Network Open

Commentaries:

Contextual Considerations for the Increased Risk of Mental Health Problems Following Concussion in Youth – JAMA Network Open

Concussion Linked to Mental Health Issues Among Children Aged 5 to 18 Years – HealthDay

 


Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents.

22 Mar, 2022 | 08:34h | UTC

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Related: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

 


Observational Study: Comparison of intracranial pressure measurements before and after hypertonic saline or mannitol treatment in children with severe traumatic brain injury.

14 Mar, 2022 | 00:51h | UTC

Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury – JAMA Network Open

Invited Commentary: ADAPTing to a New Era of Comparative Effectiveness Research in Traumatic Brain Injury—Generating Evidence From Observational Data – JAMA Network Open

 

Commentary on Twitter

 


Association of acute respiratory failure in early childhood with long-term neurocognitive outcomes.

9 Mar, 2022 | 08:41h | UTC

Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link to abstract – $ for full-text)

Commentaries:

IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay

Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes – University of Pennsylvania School of Nursing

 


Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.

4 Mar, 2022 | 09:54h | UTC

Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children’s Study – JAMA Pediatrics

Commentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay

Related:

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

 


Mortality from congenital Zika Syndrome — nationwide cohort study in Brazil.

24 Feb, 2022 | 10:18h | UTC

Mortality from Congenital Zika Syndrome — Nationwide Cohort Study in Brazil – New England Journal of Medicine

 


Opinion | There’s no autism epidemic. But there is an autism diagnosis epidemic.

13 Feb, 2022 | 22:02h | UTC

There’s no autism epidemic. But there is an autism diagnosis epidemic – STAT

 


Study shows a lack of association of Group A Streptococcal infections and onset of tics.

13 Feb, 2022 | 22:04h | UTC

Lack of Association of Group A Streptococcal Infections and Onset of Tics: European Multicenter Tics in Children Study – Neurology (link to abstract – $ for full-text)

News Release: Does strep throat lead to the development of tics? – American Academy of Neurology

Commentaries:

Strep Does Not Lead to Tics, Study Finds – NeurologyToday

Group A Strep Infection Not Tied to Tics in Children With Family History – HealthDay

 

Commentary on Twitter

https://twitter.com/ChristosGanos/status/1491415406418231300

 


Babies born during pandemic’s first year score slightly lower on a developmental screening test.

11 Feb, 2022 | 08:46h | UTC

News Release: Babies born during pandemic’s first year score slightly lower on a developmental screening test – Columbia University Irving Medical Center

Original Study: Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection – JAMA Pediatrics

Editorial: Understanding the Effects of the Pandemic on Infant Development—The Preterm Problem

Commentaries:

Covid-19: Babies born during the pandemic show slight development delays – The BMJ

Pandemic birth tied to poor development – CIDRAP

 


Concussion management is changing as more research suggests exercise is the best approach.

1 Feb, 2022 | 08:27h | UTC

Concussion management is changing as more research suggests exercise is best approach – The Conversation

Related:

Guideline: Nonpharmacological treatment of persistent postconcussion symptoms in adults.

RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

 


Cohort Study: Association of preeclampsia and perinatal complications with offspring neurodevelopmental and psychiatric disorders.

30 Jan, 2022 | 13:51h | UTC

Association of Preeclampsia and Perinatal Complications With Offspring Neurodevelopmental and Psychiatric Disorders – JAMA Network Open

 


WHO systematic review and meta-analysis: efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children.

28 Jan, 2022 | 08:27h | UTC

Efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children: a WHO systematic review and meta-analysis – Pain

 


5 years later, researchers assess how children exposed to Zika are developing.

14 Jan, 2022 | 07:53h | UTC

5 years later, researchers assess how children exposed to Zika are developing – NPR

Related: Study: Neurodevelopmental Abnormalities in Children with in Utero Zika Virus Exposure Without Congenital Zika Syndrome

 


The COVID generation: how is the pandemic affecting kids’ brains?

13 Jan, 2022 | 08:53h | UTC

The COVID generation: how is the pandemic affecting kids’ brains? – Nature

 


RCT: In full-term and near-term neonates, drug treatment of all clinically and electrographically detected seizures was not associated with reduced death rates or disability at 2 years compared with the treatment of only the clinically detected seizures.

13 Jan, 2022 | 08:24h | UTC

Effect of Treatment of Clinical Seizures vs Electrographic Seizures in Full-Term and Near-Term Neonates: A Randomized Clinical Trial – JAMA Network Open

Commentaries:

Should we treat electrographic seizures? – Neonatal Research

Subclinical Electrographic Seizures in the Newborn—Is More Treatment Better? – JAMA Network Open

Neonatal Seizures: Little Difference Between EEG/Clinical Treatment – Physician’s Weekly

 

Commentary on Twitter

 


RCT: Oxytocin does not improve social functioning in children with autism spectrum disorder.

14 Oct, 2021 | 09:52h | UTC

News release: Oxytocin does not improve social functioning in children with autism spectrum disorder, NIH-funded study suggests – National Institutes of Health

Original study: Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder – New England Journal of Medicine

 


RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

11 Oct, 2021 | 23:58h | UTC

Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial – The Lancet Child & Adolescent Health

News release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo

Related:

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

 

Commentaries on Twitter

 


Neurological Effects of COVID-19 in Children.

1 Oct, 2021 | 10:40h | UTC

Neurological Effects of COVID-19 in Children – Pediatric Clinics of North America

 


RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.

21 Sep, 2021 | 09:01h | UTC

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)

Commentaries:

Intervening Before 18 Months May Reduce Odds of Autism Diagnosis in Babies Identified at High Risk – Psychiatric News Alert

Expert reaction to trial looking at the effect of a pre-emptive intervention in children showing early signs of autism on developmental outcomes – Science Media Centre

Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian

 

Commentary on Twitter

 


RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

12 Sep, 2021 | 21:38h | UTC

News release: Limiting screen time for young adults after concussion results in shorter duration of symptoms – University of Massachusetts Medical School

Original study: Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

 

Commentary on Twitter

 


[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.

16 Aug, 2021 | 01:11h | UTC

Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Health – medRxiv

Commentary: Children born during pandemic have lower IQs, US study finds – Researchers blame lack of stimulation as parents balanced childcare with working from home – The Guardian

 

Commentary on Twitter (thread – click for more)

 


European guideline and expert statements on the management of narcolepsy in adults and children.

13 Aug, 2021 | 09:02h | UTC

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

 


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