Pediatrics (all articles)
AAP Policy Statement: The Use of Nonnutritive Sweeteners in Children
3 Nov, 2019 | 20:15h | UTCThe Use of Nonnutritive Sweeteners in Children – Pediatrics (free)
News Release: Nonnutritive sweetener use in children – American Academy of Pediatrics (free)
Commentary: AAP: Too Much Unknown About Sugar Substitutes’ Effects on Kids – MedPage Today (free registration required)
[Abstract Only] Randomized Trial: Triple Therapy Effective for the Treatment of Cystic Fibrosis
1 Nov, 2019 | 10:22h | UTCElexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)
Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)
Related Commentary on Twitter
Triple treatment of CF patients with one Phe508del allele and one minimal function allele with elexacaftor, tezacaftor and ivacaftor resulted in sustained improvement in FEV1, sweat chloride, and the number of pulmonary exacerbations. #NACFC https://t.co/ATeGlBUWCp
— NEJM (@NEJM) October 31, 2019
Research: Measles Virus Infection Diminishes Preexisting Antibodies that Offer Protection from Other Pathogens
1 Nov, 2019 | 08:45h | UTCMeasles virus infection diminishes preexisting antibodies that offer protection from other pathogens – Science (free for a limited period)
Related Research: Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles – Science Immunology (free for a limited period)
Commentaries: How measles infections can wipe away immunity to other diseases – STAT (free) AND Measles wipe immune system’s memory of other illnesses, studies find – CNN (free) AND Measles Virus May Wipe Out Immune Protection For Other Diseases – NPR (free) AND Measles vaccines protect against more than just measles. Here’s how. – National Geographic (free) AND Measles Infection Could Leave Kids Vulnerable to Other Diseases – Scientific American (free)
Related Commentary on Twitter
The measles infection can cripple long-term immunity against viruses and bacteria, creating a kind of “immune amnesia” that leaves individuals more vulnerable to future infections by other pathogens, according to two studies:
▶ https://t.co/te7kr7N7Ju
▶ https://t.co/tiSTrvyQob pic.twitter.com/taaN3KIMPk— Science Magazine (@ScienceMagazine) October 31, 2019
Global Burden, Risk Factors, and Interventions for Lower Respiratory Infections Among Children Younger than 5 Years
1 Nov, 2019 | 08:24h | UTCInvited Commentary: Trends in the global burden of paediatric lower respiratory infections (free)
News Release: New study finds one in seven child deaths result from pneumonia, the flu, and other lower respiratory infections – Institute for Health Metrics and Evaluation (free)
Related: Global Burden of Pneumonia in Children Younger than 5 Years (free)
Related Commentary on Twitter
New online: Quantifying risks and interventions that have affected
the burden of lower respiratory infections among children
younger than 5 years: an analysis for the Global Burden of
Disease Study 2017 https://t.co/m9eg8Kbhki #GBDStudy #influenza #pneumonia@IHME_UW pic.twitter.com/5yuzuLmE0c— The Lancet Infectious Diseases (@TheLancetInfDis) October 30, 2019
Global Burden, Risk Factors, and Interventions for Diarrhea Among Children Younger than 5 Years
1 Nov, 2019 | 08:09h | UTCInvited Commentary: Early childhood diarrhoea: from data to interventions (free)
Related Global Burden of Disease Report: Global Burden of Diarrhea (free)
Related Commentary on Twitter
Our study, "Quantifying risks and interventions that have affected the burden of diarrhoea among children younger than 5 years: an analysis of the Global Burden of Disease Study 2017" was published in @TheLancetInfDis. Read the open access study online: https://t.co/evz4CWyowu pic.twitter.com/9SSxebzPYm
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) October 31, 2019
Congenital Chagas Disease: Updated Recommendations
30 Oct, 2019 | 07:44h | UTC
Report on Advances for Pediatricians in 2018
30 Oct, 2019 | 07:51h | UTC
Systematic Review: Botulinum Toxin Type A in the Treatment of Lower Limb Spasticity in Children with Cerebral Palsy
30 Oct, 2019 | 07:42h | UTCBotulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy – Cochrane Library (free)
Summary: Botulinum toxin type A injections for the treatment of lower limb spasticity in cerebral palsy – Cochrane Library (free)
AAP Policy Statement: Pediatric Metabolic and Bariatric Surgery
28 Oct, 2019 | 00:48h | UTCPediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best Practices – Pediatrics (free)
Technical Report: Metabolic and Bariatric Surgery for Pediatric Patients With Severe Obesity – Pediatrics (free)
Commentary: More kids should get weight-loss surgery, even some preteens, pediatricians say – STAT / Associated Press (free)
Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis
27 Oct, 2019 | 23:39h | UTCSee other articles in the series: Choosing Wisely: Things We Do For No Reason (free)
Randomized Trial: Fluoxetine Does Not Improve Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders
24 Oct, 2019 | 08:43h | UTCEffect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Study finds little evidence on effectiveness of common antidepressant in autism spectrum disorders – News Medical (free) AND Prozac proves no better than a placebo in treating kids with autism – ScienceNews (free)
Study: Prevalence and Factors Associated with Safe Infant Sleep Practices
24 Oct, 2019 | 08:45h | UTCPrevalence and Factors Associated with Safe Infant Sleep Practices – Pediatrics (free)
Commentaries: Doctors still need to tell parents about safe infant sleep practices – Reuters (free) AND Safe infant sleep practices remain underutilized – 2 Minute Medicine (free)
Study: Heavier Social Media Use Associated with Poorer Sleep Patterns
24 Oct, 2019 | 07:22h | UTCCommentaries: More LOLs, Fewer Zzzs: Teens May Be Losing Sleep Over Social Media – NPR (free) AND High social media use linked to poor sleep in teens – OnMedica (free) AND Heavy social media use linked to poor sleep – BBC (free)
Mapping 123 Million Neonatal, Infant and Child Deaths Between 2000 and 2017
23 Oct, 2019 | 08:25h | UTCMapping 123 million neonatal, infant and child deaths between 2000 and 2017 – Nature (free)
Commentaries: Tackling inequality could save millions of children – Institute for Health Metrics and Evaluation (free) AND Where You’re Born Even Within A Country Still Matters – NPR (free)
Related Commentary on Twitter
A map of death rates in children under 5 years old from low- and middle-income countries estimates that 123 million died between 2000 and 2017, according to a Nature report. The study explores how a child’s risk of dying depends on where they are born. https://t.co/IzjvO43bVz pic.twitter.com/p6LNIp54tB
— Nature Portfolio (@NaturePortfolio) October 22, 2019
Study: Prevalence of Survival Without Major Comorbidities Among Adults Born Prematurely
23 Oct, 2019 | 08:04h | UTCPrevalence of Survival Without Major Comorbidities Among Adults Born Prematurely – JAMA (free for a limited period)
Commentary: Researchers Find That Most Adults Born Prematurely Survive Without Major Comorbidities – Mount Sinai Health System (free)
[Abstract Only] Study: Pan-viral Serology Implicates Enteroviruses in Acute Flaccid Myelitis
22 Oct, 2019 | 08:08h | UTCPan-viral serology implicates enteroviruses in acute flaccid myelitis – Nature (link to abstract – $ for full-text)
Commentaries: ‘Missing’ Virus Detected in Dozens of Children Paralyzed by Polio-Like Illness – UC San Francisco (free) AND What Causes a Mysterious Paralysis in Children? Researchers Find Viral Clues – The New York Times (10 articles per month are free) AND Virus could be the cause of mysterious polio-like illness AFM, study says – CNN (free)
Review: Eosinophilic Gastrointestinal Diseases in Childhood
22 Oct, 2019 | 07:18h | UTCEosinophilic Gastrointestinal Diseases in Childhood – Annals of Nutrition & Metabolism (free)
Urinary Tract Infections in Children: An Overview of Diagnosis and Management
18 Oct, 2019 | 08:19h | UTCUrinary tract infections in children: an overview of diagnosis and management – BMJ Paediatrics Open (free)
[Abstract Only] Study: 20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia
17 Oct, 2019 | 08:27h | UTC20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: For Kids With Genetic Condition, Statins May Be Lifesavers – U.S. News (free) AND Starting Statin in Childhood Protects FH Hearts – MedPage Today (free registration required) AND Making the Case for Early Statins in Familial Hypercholesterolemia – Medscape (free registration required)
Study: Youth Suicide Attempts Often Involve Over-the-counter Painkillers
15 Oct, 2019 | 10:16h | UTCYouth suicide attempts often involve over-the-counter painkillers – Reuters (free)
Original Study: Suicide attempts by self-poisoning in the United States among 10–25 year olds from 2000 to 2018: substances used, temporal changes and demographics – Journal of Clinical Toxicology (free)
Special Issue: Neonatal ECMO in 2019
15 Oct, 2019 | 10:11h | UTCHomepage: Neonatal ECMO in 2019: Where Are We Now? Where Next? – Frontiers in Pediatrics (free articles)
– Anticoagulation in Neonatal ECMO: An Enigma Despite a Lot of Effort!
– Drug Disposition and Pharmacotherapy in Neonatal ECMO: From Fragmented Data to Integrated Knowledge
– Neonatal Cardiac ECMO in 2019 and Beyond
– Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia
Guideline: Management of Severe Asthma Exacerbation
11 Oct, 2019 | 09:47h | UTC
AAP Policy Statement: Recommendations for Prevention and Control of Influenza in Children, 2019–2020
14 Oct, 2019 | 08:05h | UTCRecommendations for Prevention and Control of Influenza in Children, 2019–2020 – Pediatrics (free)
News Release: Recommendations for Prevention and Control of Influenza in Children, 2019-2020 – American Academy of Pediatrics (free)
[Abstract Only] Randomized Trial: Controlled Trial of Two Incremental Milk-Feeding Rates in Preterm Infants
10 Oct, 2019 | 09:32h | UTCControlled Trial of Two Incremental Milk-Feeding Rates in Preterm Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Speed of increasing milk feeds does not affect neurodevelopmental outcomes in preterm infants – Healio (free registration required)
NICE Guideline: Gastroesophageal Reflux Disease in Children and Young People
9 Oct, 2019 | 10:46h | UTC