Pediatrics (all articles)
Antenatal interventions for preventing stillbirth, fetal loss and perinatal death: an overview of Cochrane systematic reviews
21 Jan, 2021 | 00:59h | UTCCommentary: What are the most effective interventions during pregnancy for preventing stillbirth? – Cochrane Library
Commentary on Twitter
@CochranePCG overview of Cochrane systematic reviews included 43 Cochrane reviews that assessed 61 different ways of preventing stillbirth during pregnancy, or infant deaths around the time of birth. Read the feature https://t.co/ijf9Id8jjO & full review https://t.co/tMZsCVhs3m
— Cochrane Neonatal (@CochraneNeonate) January 7, 2021
Randomized trial: Dabigatran non-inferior to standard of care for children with acute venous thromboembolism
21 Jan, 2021 | 00:35h | UTCDabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial – The Lancet Haematology (link to abstract – $ for full-text)
WHO urges governments to promote healthy food in public facilities
19 Jan, 2021 | 01:40h | UTCWHO urges governments to promote healthy food in public facilities – World Health Organization
Original Report: Action framework for developing and implementing public food procurement and service policies for a healthy diet – World Health Organization
Commentary on Twitter
Governments worldwide have a responsibility to serve and sell food that improves the health of their people. @WHO's new action framework is an opportunity to make healthy food choices the default choices in public settings. https://t.co/NdUtXBNSL1
— Dr. Tom Frieden (@DrTomFrieden) January 18, 2021
Systematic review: Little evidence of benefit from vitamin D supplementation on linear growth and other health outcomes among children under five years of age
19 Jan, 2021 | 01:11h | UTC
Randomized trial: Vitamin D does not improve growth or reduce rickets in stunted children
19 Jan, 2021 | 01:07h | UTCVitamin D for Growth and Rickets in Stunted Children: A Randomized Trial – Pediatrics
Progression of myopia in school-aged children after COVID-19 home confinement
15 Jan, 2021 | 08:55h | UTCProgression of Myopia in School-Aged Children After COVID-19 Home Confinement – JAMA Ophthalmology
Commentaries: 2020 as the Year of Quarantine Myopia – JAMA Ophthalmology AND How Does Home Confinement Impact Children’s Eyesight? – AJMC AND COVID-19: Home Quarantine Linked to Increase in Myopia Among Younger Children – NEJM Journal Watch AND Vision problems arise in young school kids in COVID-19 quarantine – CIDRAP
Interview: 2020 as the Year of Quarantine Myopia
Randomized trial: Cannula with long and narrow tubing noninferior to short binasal prongs for noninvasive ventilation in preterm infants
15 Jan, 2021 | 08:15h | UTCCannula With Long and Narrow Tubing vs Short Binasal Prongs for Noninvasive Ventilation in Preterm Infants: Noninferiority Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Israeli study finds effective, less invasive way to treat preterm babies – The Jerusalem Post
Commentary on Twitter
New RCT on @JAMAPediatrics shows cannulas with long and narrow tubing (CLNT) to be noninferior to short binasal prongs and masks (SPM) in providing NIPPV for preterm infants, while causing significantly less nasal trauma: https://t.co/zdW6zcM7NY #neoEBM #ebneoalerts pic.twitter.com/Q9qBQLxdwT
— Evidence-Based Neo (@EBNEO) November 15, 2020
Three studies highlight low COVID risk of in-person school
14 Jan, 2021 | 02:06h | UTCThree studies highlight low COVID risk of in-person school – CIDRAP
Study 1: Open Schools, Covid-19, and Child and Teacher Morbidity in Sweden – New England Journal of Medicine
Study 2: Incidence and Secondary Transmission of SARS-CoV-2 Infections in Schools – Pediatrics
Randomized trial: First-line treatment with infliximab vs. conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease
14 Jan, 2021 | 01:27h | UTC
AAP: COVID-19 Guidance for Safe Schools
12 Jan, 2021 | 01:56h | UTCCOVID-19 Guidance for Safe Schools – American Academy of Pediatrics
Commentary: AAP updates guidance for in-school education – Contemporary Pediatrics
Three-year follow-up of 2-dose versus 3-dose HPV vaccine
12 Jan, 2021 | 01:26h | UTCThree-Year Follow-up of 2-Dose Versus 3-Dose HPV Vaccine – Pediatrics (link to abstract – $ for full-text)
Systematic review: Prevention of childhood unintentional injuries in low- and middle-income countries
12 Jan, 2021 | 01:23h | UTCRelated: World report on child injury prevention – World Health Organization
Randomized trial: In extremely-low-birth-weight infants, a higher hemoglobin threshold for red-cell transfusion does not improve outcomes
10 Jan, 2021 | 20:36h | UTCHigher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Higher red cell transfusion threshold offers no advantage for treating preterm infants – NIH News Releases
AAP Guideline: Identification and management of eating disorders in children and adolescents
10 Jan, 2021 | 20:30h | UTCIdentification and Management of Eating Disorders in Children and Adolescents – Pediatrics
Commentary: Pediatrics Group Offers Guidance on Managing Eating Disorders in Youth – NEJM Journal Watch
Systematic review: Effectiveness of hospital clowns for symptom management in pediatrics
10 Jan, 2021 | 20:24h | UTCCommentaries: Clowns may help children cope with the pain and anxiety of hospital treatment – The BMJ AND Clowns Make Hospitals Less Scary For Young Patients – Forbes AND Laughter As Medicine: Clowns Help Hospitalized Kids Cope – U.S News
Commentary on Twitter
As a gift 🎁 to children everywhere, a @bmj_latest study shows that sending in the clowns – in pediatric hospital settings – may reduce children's stress, fatigue, #pain, and distress during a range of medical procedures"
By @lopesjr_phd, @Naramata4 et al#bioethics #ChronicPain pic.twitter.com/hmnXRv3J8Q— Sandra Woods, CIPP/C; she/her (@SandraWoodsMtl) December 25, 2020
Observational study: Childhood growth hormone treatment linked to increased risks of cardiovascular events in early adulthood
10 Jan, 2021 | 20:27h | UTCAssociation of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Childhood Tx with Growth Hormone May Up Cardiovascular Risks Later – Physician’s Weekly AND Growth Hormones in Childhood Tied to Heart Problems Later On – MedPage Today (free registration required)
Medical errors in the pediatric emergency department: Don’t make these mistakes!
10 Jan, 2021 | 20:21h | UTC
Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicenter collaborative study
18 Dec, 2020 | 09:50h | UTCCommentary: Study highlights neurological impact of COVID-19 on children – University of Manchester
Commentary on Twitter (thread – click for more)
New #COVID19 Research: An international call for cases identified 38 children with neurological disease related to #SARSCoV2 infection
Recurring patterns of disease were identified, with #neuroimaging abnormalities ranging from mild to severehttps://t.co/a3bjPlOY0z pic.twitter.com/W0lxLP4aAh
— The Lancet Child & Adolescent Health (@LancetChildAdol) December 16, 2020
Randomized trial: In small infants, orotracheal intubation assisted with video laryngoscopy improves first-attempt success rate and reduces complications
17 Dec, 2020 | 08:56h | UTCFirst-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Fascinating paediatric VL study
VL
-improved FPS (esp <6.5kg)
& reduced
-attempts
-failures
-manipulations
-complications
-severe complicationsThe evidence grows that VL is simply better
Everywherehttps://t.co/f9nj6l2zk3— Tim Cook (@doctimcook) December 11, 2020
Systematic review: “Early or very early pharmacotherapeutic treatment of a hemodynamically significant patent ductus arteriosus probably does not reduce mortality in preterm infants”
17 Dec, 2020 | 08:58h | UTC
Commentary on Twitter (thread – click for more)
So @CochraneNeonate evidence suggest no benefit of early (<7 days) PDA Rx, possible harm: https://t.co/oRc5HlCQ5l
Would our #neoEBM community apply this to <26 wk infants? 113 from across the 🌏 responded (39🇨🇦, 23🇺🇸, 13🇸🇦, 8🇬🇧), and the results are striking! A thread.. @EBNEO— Souvik Mitra (@souvik_neo) December 11, 2020
Study shows rise in childhood depression symptoms during the COVID-19 lockdown
16 Dec, 2020 | 09:41h | UTCCommentaries: Steep rise in depressive symptoms among 7-12 year olds during UK-wide lockdown – British Medical Journal AND Children’s Depression Symptoms Up During U.K. Lockdown – Physician’s Weekly AND Expert reaction to longitudinal study of depression symptoms in children during the COVID-19 lockdown – Science Media Centre
ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2
16 Dec, 2020 | 09:32h | UTC
A meta-analysis on the role of children in SARS-CoV-2 in household transmission clusters
15 Dec, 2020 | 01:34h | UTCCommentary: Kids likely not driving household COVID-19 outbreaks – CIDRAP
Study: Children and adults equally susceptible to in-home COVID-19 spread, but children generally had less frequent and severe symptoms
15 Dec, 2020 | 01:36h | UTCCommentaries: Study: Kids, adults equally susceptible to in-home COVID-19 spread – CIDRAP AND COVID-19 in Children: Looking Forward, Not Back
Randomized trial: In acutely ill children, the risk of electrolyte disorders is markedly increased with plasmalike isotonic fluid therapy compared with moderately hypotonic fluid therapy containing 20 mmol/L of potassium
15 Dec, 2020 | 01:25h | UTCRisk of Electrolyte Disorders in Acutely Ill Children Receiving Commercially Available Plasmalike Isotonic Fluids: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Isotonic Fluids Without Potassium Could Be Harmful for Some Acutely Ill Kids – Medscape (free registration required)
Commentary on Twitter
A randomized pragmatic clinical trial shows a high risk of #hypokalemia and a small risk of #hypernatremia in acutely ill children receiving plasma-like fluid therapy https://t.co/FOoJeaSSes @TerhiTapiainen
— JAMA Pediatrics (@JAMAPediatrics) October 27, 2020