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Pediatrics (all articles)

Guideline | Prevention and therapy of preterm birth

12 Jun, 2023 | 13:45h | UTC

Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG

Part 1: Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth – Geburtshilfe und Frauenheilkunde

Part 2: Recommendations on the Tertiary Prevention of Preterm Birth and on the Management of Preterm Premature Rupture of Membranes – Geburtshilfe und Frauenheilkunde

 


Guideline | Managing chemotherapy-induced nausea and vomiting in pediatric cancer

7 Jun, 2023 | 13:43h | UTC

Treatment of breakthrough and prevention of refractory chemotherapy-induced nausea and vomiting in pediatric cancer patients: Clinical practice guideline update – Pediatric Blood & Cancer

 


Adrenaline auto-injector prescription for patients at risk of anaphylaxis: BSACI guidance for primary care

6 Jun, 2023 | 14:28h | UTC

Adrenaline auto-injector prescription for patients at risk of anaphylaxis: BSACI guidance for primary care – Clinical & Experimental Allergy

 


Podcast | Hypopigmented and depigmented skin lesions in pediatrics

6 Jun, 2023 | 14:24h | UTC

#84: Hypopigmented & Depigmented Skin Lesions: An En-LIGHT-ening Review – The Cribsiders

 


Podcast | Ascend your understanding of pelvic inflammatory disease

6 Jun, 2023 | 14:23h | UTC

#83: Ascend Your Understanding of Pelvic Inflammatory Disease (PID) – The Cribsiders

 


Cohort Study | Cannabis use disorder linked to increased risk of depression and bipolar disorder

5 Jun, 2023 | 13:26h | UTC

Cannabis Use Disorder and Subsequent Risk of Psychotic and Nonpsychotic Unipolar Depression and Bipolar Disorder – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Cannabis Use Disorder and Subsequent Risk of Unipolar Depression and Bipolar Disorder

Commentary: Expert reaction to study of cannabis use disorder, bipolar disorder, and depression – Science Media Centre

 


Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care

1 Jun, 2023 | 11:58h | UTC

Implementation of point-of-care testing of C-reactive protein concentrations to improve antibiotic targeting in respiratory illness in Vietnamese primary care: a pragmatic cluster-randomised controlled trial – The Lancet Infectious Diseases

Commentary: Use of CRP testing reduced antibiotics for respiratory infections, trial finds – CIDRAP

 


M-A | Labor induction at 39 weeks: improved outcomes but increased shoulder dystocia for nulliparous women

31 May, 2023 | 14:10h | UTC

Comparison of Maternal Labor-Related Complications and Neonatal Outcomes Following Elective Induction of Labor at 39 Weeks of Gestation vs Expectant Management: A Systematic Review and Meta-analysis – JAMA Network Open

 


Review | Invasive mold infections in children: navigating troubled waters with a broken compass

31 May, 2023 | 14:05h | UTC

Invasive Mold Infections in Children: Navigating Troubled Waters with a Broken Compass – Infectious Diseases and Therapy

 


M-A | Shorter vs. longer-term antibiotic treatments for community-acquired pneumonia in children

31 May, 2023 | 13:42h | UTC

Shorter Versus Longer-term Antibiotic Treatments for Community-Acquired Pneumonia in Children: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)

Commentary: Meta-analysis supports shorter antibiotic courses for kids’ pneumonia – CIDRAP

Related:

M-A | Examining shorter antibiotic treatment durations for community acquired pneumonia in adults

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

Short-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis – JAMA Pediatrics

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

 


Current guidelines for perioperative management and transfusion decisions in sickle cell patients

30 May, 2023 | 11:57h | UTC

Current Evidence and Rationale to Guide Perioperative Management, Including Transfusion Decisions, in Patients With Sickle Cell Disease – Anesthesia & Analgesia

 


Review | Child and adolescent obesity

30 May, 2023 | 11:45h | UTC

Child and adolescent obesity – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 


AHA Scientific Statement | Basic life support education for schoolchildren

25 May, 2023 | 11:37h | UTC

KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren: A Narrative Review and Scientific Statement From the International Liaison Committee on Resuscitation – Circulation

News Release: Learning to save lives can start as early as age 4, according to new scientific statement – American Heart Association

Top Things to Know: KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren – American Heart Association

 


WHO Report | Global progress in tackling maternal and newborn deaths stalls since 2015

25 May, 2023 | 11:36h | UTC

News Release: Global progress in tackling maternal and newborn deaths stalls since 2015: UN – World Health Organization

Report: Improving maternal and newborn health and survival and reducing stillbirth – Progress report 2023 – World Health Organization

 


Current recommendations for the management of pediatric diabetic ketoacidosis

25 May, 2023 | 11:31h | UTC

Current recommendations for management of paediatric diabetic ketoacidosis – Paediatrics & Child Health

 


Graves’ disease in children: an update

25 May, 2023 | 11:18h | UTC

Graves’ Disease in Children: An Update – Clinical Medicine Insights: Endocrinology and Diabetes

 


SR | Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhea and severe dehydration in children

25 May, 2023 | 11:15h | UTC

Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children – Cochrane Library

Summary: Balanced crystalloid solutions versus 0.9% saline for severely dehydrated children with acute diarrhoea – Cochrane Library

 


SR | Videolaryngoscopy vs. direct laryngoscopy for tracheal intubation in neonates

24 May, 2023 | 13:11h | UTC

Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates – Cochrane Library

 

Commentary on Twitter

 


WHO Report | 152 million babies born preterm in the last decade

23 May, 2023 | 13:15h | UTC

News Release: 152 million babies born preterm in the last decade – World Health Organization

Report: Born too soon: decade of action on preterm birth – World Health Organization

 


The Lancet Series | Small vulnerable newborns

23 May, 2023 | 13:13h | UTC

News Release: An estimated 1 million stillbirths and newborn baby deaths could be prevented each year with low-cost solutions – Lancet

Homepage: Small vulnerable newborns – The Lancet (free registration required for all articles)

Small vulnerable newborns—big potential for impact

Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting

Biological and pathological mechanisms leading to the birth of a small vulnerable newborn

Evidence-based antenatal interventions to reduce the incidence of small vulnerable newborns and their associated poor outcomes

The ethical, economic, and developmental imperative to prevent small vulnerable newborns and stillbirths: essential actions to improve the country and global response

 


RCT | Tonsillectomy shown to be clinically and cost-effective in adults with recurrent acute tonsillitis

23 May, 2023 | 13:06h | UTC

Summary: The NATTINA trial, a pragmatic multicentre, open-label, randomized controlled study, sought to compare the clinical and cost-effectiveness of conservative management versus tonsillectomy in adults with recurrent acute tonsillitis. Conducted across 27 UK hospitals, 453 participants aged 16 or older were randomly assigned to either undergo immediate tonsillectomy or receive standard non-surgical care.

The main finding was that participants in the immediate tonsillectomy group had fewer days of sore throat over a 24-month period than those in the conservative management group (median 23 vs. 30 days). After adjusting for site and baseline severity, the incident rate ratio of total sore throat days in the immediate tonsillectomy group was significantly lower than in the conservative management group (0.53, 95% CI 0.43 to 0.65, p < 0.0001). The most common adverse event related to tonsillectomy was bleeding, which occurred in 19% of participants.

The NATTINA trial is the largest to date assessing the clinical and cost-effectiveness of tonsillectomy in adults. The results indicate that immediate tonsillectomy is clinically effective and cost-effective for recurrent acute tonsillitis. However, patients should weigh the benefits of fewer sore throat days against the risks of surgery.

Article: Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial – The Lancet

News Release: Tonsillectomy both clinically and cost effective for adults – Newcastle University

 

Commentary on Twitter

 


M-A | Inhaled nitrous oxide for painful procedures in children and youth

22 May, 2023 | 13:29h | UTC

Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis – Canadian Journal of Emergency Medicine

 


RCT | Peanut patch therapy is effective in desensitizing young children with allergies, but raises risk of serious adverse events

15 May, 2023 | 13:10h | UTC

Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


SR | Nasal high flow therapy for primary respiratory support in preterm infants

12 May, 2023 | 13:31h | UTC

Nasal high flow therapy for primary respiratory support in preterm infants – Cochrane Library

Summary: Nasal high flow therapy for breathing support in preterm babies – Cochrane Library

 

Commentary on Twitter

 


FDA warns of use of selective androgen receptor modulators (SARMs) among teens, young adults

10 May, 2023 | 16:00h | UTC

FDA Warns of Use of Selective Androgen Receptor Modulators (SARMs) Among Teens, Young Adults – U.S. Food & Drug Administration

Commentaries:

FDA issues warning for bodybuilding products marketed to teens, young adults – AAP News

Young Men Are Using Banned ‘SARM’ Supplements to Bulk Up, With Harmful Results – HealthDay


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