Pediatrics (all articles)
Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care
1 Jun, 2023 | 11:58h | UTCCommentary: Use of CRP testing reduced antibiotics for respiratory infections, trial finds – CIDRAP
M-A | Labor induction at 39 weeks: improved outcomes but increased shoulder dystocia for nulliparous women
31 May, 2023 | 14:10h | UTC
Review | Invasive mold infections in children: navigating troubled waters with a broken compass
31 May, 2023 | 14:05h | UTC
M-A | Shorter vs. longer-term antibiotic treatments for community-acquired pneumonia in children
31 May, 2023 | 13:42h | UTCShorter Versus Longer-term Antibiotic Treatments for Community-Acquired Pneumonia in Children: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentary: Meta-analysis supports shorter antibiotic courses for kids’ pneumonia – CIDRAP
Related:
M-A | Examining shorter antibiotic treatment durations for community acquired pneumonia in adults
Current guidelines for perioperative management and transfusion decisions in sickle cell patients
30 May, 2023 | 11:57h | UTC
Review | Child and adolescent obesity
30 May, 2023 | 11:45h | UTCChild and adolescent obesity – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Commentary on Twitter
A Primer in @DiseasePrimers discusses the epidemiology, mechanisms, diagnosis, prevention and management of obesity in children and adolescents, highlighting patient quality of life and areas for further research. https://t.co/Zpcb4RbH2J pic.twitter.com/uneXxVyTDg
— Nature Portfolio (@NaturePortfolio) May 28, 2023
AHA Scientific Statement | Basic life support education for schoolchildren
25 May, 2023 | 11:37h | UTCNews Release: Learning to save lives can start as early as age 4, according to new scientific statement – American Heart Association
Top Things to Know: KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren – American Heart Association
WHO Report | Global progress in tackling maternal and newborn deaths stalls since 2015
25 May, 2023 | 11:36h | UTCNews Release: Global progress in tackling maternal and newborn deaths stalls since 2015: UN – World Health Organization
Current recommendations for the management of pediatric diabetic ketoacidosis
25 May, 2023 | 11:31h | UTC
Graves’ disease in children: an update
25 May, 2023 | 11:18h | UTCGraves’ Disease in Children: An Update – Clinical Medicine Insights: Endocrinology and Diabetes
SR | Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhea and severe dehydration in children
25 May, 2023 | 11:15h | UTC
SR | Videolaryngoscopy vs. direct laryngoscopy for tracheal intubation in neonates
24 May, 2023 | 13:11h | UTCVideolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates – Cochrane Library
Commentary on Twitter
Videolaryngoscopy:
– may increase the success of intubation on 1st attempt and result in fewer intubation attempts, but may not reduce the time required for successful intubation
– likely results in a reduced incidence of airway‐related adverse effectshttps://t.co/ney0pt8PnH pic.twitter.com/lc6bbDME7e— Cochrane Neonatal (@CochraneNeonate) May 12, 2023
WHO Report | 152 million babies born preterm in the last decade
23 May, 2023 | 13:15h | UTCNews Release: 152 million babies born preterm in the last decade – World Health Organization
Report: Born too soon: decade of action on preterm birth – World Health Organization
The Lancet Series | Small vulnerable newborns
23 May, 2023 | 13:13h | UTCNews Release: An estimated 1 million stillbirths and newborn baby deaths could be prevented each year with low-cost solutions – Lancet
Homepage: Small vulnerable newborns – The Lancet (free registration required for all articles)
Small vulnerable newborns—big potential for impact
Biological and pathological mechanisms leading to the birth of a small vulnerable newborn
RCT | Tonsillectomy shown to be clinically and cost-effective in adults with recurrent acute tonsillitis
23 May, 2023 | 13:06h | UTCSummary: The NATTINA trial, a pragmatic multicentre, open-label, randomized controlled study, sought to compare the clinical and cost-effectiveness of conservative management versus tonsillectomy in adults with recurrent acute tonsillitis. Conducted across 27 UK hospitals, 453 participants aged 16 or older were randomly assigned to either undergo immediate tonsillectomy or receive standard non-surgical care.
The main finding was that participants in the immediate tonsillectomy group had fewer days of sore throat over a 24-month period than those in the conservative management group (median 23 vs. 30 days). After adjusting for site and baseline severity, the incident rate ratio of total sore throat days in the immediate tonsillectomy group was significantly lower than in the conservative management group (0.53, 95% CI 0.43 to 0.65, p < 0.0001). The most common adverse event related to tonsillectomy was bleeding, which occurred in 19% of participants.
The NATTINA trial is the largest to date assessing the clinical and cost-effectiveness of tonsillectomy in adults. The results indicate that immediate tonsillectomy is clinically effective and cost-effective for recurrent acute tonsillitis. However, patients should weigh the benefits of fewer sore throat days against the risks of surgery.
News Release: Tonsillectomy both clinically and cost effective for adults – Newcastle University
Commentary on Twitter
Compared with conservative management, immediate tonsillectomy is clinically effective and cost-effective in adults with recurrent acute #tonsillitis, suggests trial. https://t.co/LvSjn6XUx0 pic.twitter.com/yKzH9RqY5J
— The Lancet (@TheLancet) May 18, 2023
M-A | Inhaled nitrous oxide for painful procedures in children and youth
22 May, 2023 | 13:29h | UTC
RCT | Peanut patch therapy is effective in desensitizing young children with allergies, but raises risk of serious adverse events
15 May, 2023 | 13:10h | UTCPhase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In the phase 3 EPITOPE trial involving children 1 to 3 years of age with peanut allergy, epicutaneous immunotherapy by means of a peanut patch was superior to placebo in desensitizing children to peanut. https://t.co/USk6HBI9Qh#pediatrics
— NEJM (@NEJM) May 10, 2023
SR | Nasal high flow therapy for primary respiratory support in preterm infants
12 May, 2023 | 13:31h | UTCNasal high flow therapy for primary respiratory support in preterm infants – Cochrane Library
Summary: Nasal high flow therapy for breathing support in preterm babies – Cochrane Library
Commentary on Twitter
Nasal high flow therapy for primary respiratory support in preterm infants – 2023 updatehttps://t.co/6UEnZ8fJRS @AmerAcadPeds @ESPR_ESN pic.twitter.com/yLBcQPPPvS
— Cochrane Neonatal (@CochraneNeonate) May 6, 2023
FDA warns of use of selective androgen receptor modulators (SARMs) among teens, young adults
10 May, 2023 | 16:00h | UTCCommentaries:
FDA issues warning for bodybuilding products marketed to teens, young adults – AAP News
Young Men Are Using Banned ‘SARM’ Supplements to Bulk Up, With Harmful Results – HealthDay
RCT | Effect of repeated low-level red light on myopia prevention among children in China with premyopia
10 May, 2023 | 15:52h | UTCCommentary: Repeated Low-Level Red-Light Intervention Prevents Myopia in Children – HealthDay
Related:
RCT | Effect of low-concentration atropine eyedrops vs. placebo on myopia incidence in children
Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.
RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.
RCT | Myopia control effect of repeated low-level red-light therapy in children.
Commentary on Twitter
RCT: Repeated low-level red-light (RLRL) is a novel and effective intervention for myopia prevention in children with premyopia, up to 54% reduction in incident myopia within 12 months, with good user acceptability and safety. https://t.co/geMajH5ms8
— JAMA Network Open (@JAMANetworkOpen) April 26, 2023
Guideline | Assessment and treatment of children and adolescents with major and persistent depressive disorders
10 May, 2023 | 15:37h | UTC
M-A | Impact on childhood mortality of interventions to improve drinking water, sanitation, and hygiene to households
10 May, 2023 | 15:28h | UTC
Review | Pediatric pericarditis
9 May, 2023 | 14:42h | UTCPediatric Pericarditis: Update – Current Cardiology Reports
Cohort Study | Long-term risk of epilepsy following invasive Group B Streptococcus disease in neonates
9 May, 2023 | 14:25h | UTC
4 or more CT scans in childhood correlate with elevated cancer risk
4 May, 2023 | 13:59h | UTCNews Release: Single CT scan in kids low risk for cancers, but 4 or more CTs increases risk – Canadian Medical Association Journal